Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Example Evidence: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Courcoulas 2015

Active as of 2022-05-29

Generated Narrative: Evidence 47768

version: 11; Last updated: 2023-12-06 18:55:48+0000

Profiles: ComparativeEvidence, SingleStudyEvidence

url: Evidence ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Courcoulas 2015

identifier: FEvIR Object Identifier/47768, Uniform Resource Identifier (URI)/urn:oid:2.16.840.1.113883.4.642.40.44.22.22

version: 2.0.0-ballot

name: ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Courcoulas_2015

title: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Courcoulas 2015

status: Active

date: 2022-05-29 10:56:54+0000

publisher: HL7 International / Clinical Decision Support

contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss

author: Brian S. Alper:

UseContexts

-CodeValue[x]
*Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence CommunicationComparativeEvidence
*Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence CommunicationSingleStudyEvidence

copyright:

https://creativecommons.org/licenses/by-nc-sa/4.0/

relatedArtifact

type: Derived From

label: data source

display: Figure 2C

citation:

Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations [Journal Article]. Contributors: Francesco Rubino, David M Nathan, Robert H Eckel, Philip R Schauer, K George M M Alberti, Paul Z Zimmet, Stefano Del Prato, Linong Ji, Shaukat M Sadikot, William H Herman, Stephanie A Amiel, Lee M Kaplan, Gaspar Taroncher-Oldenburg, David E Cummings, Delegates of the 2nd Diabetes Surgery Summit. In: Diabetes care, PMID 27222544. Published June 2016. Available at: https://pubmed.ncbi.nlm.nih.gov/27222544/.

Documents

-Url
*https://diabetesjournals.org/care/article/39/6/861/29305/Metabolic-Surgery-in-the-Treatment-Algorithm-for

relatedArtifact

type: Cite As

citation:

ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Courcoulas 2015 [Evidence]. Contributors: In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 47768. Revised 2022-05-29. Available at: https://fevir.net/resources/Evidence/47768. Computable resource at: https://fevir.net/resources/Evidence/47768.

description:

Mean HbA1c at 36 months in Courcoulas 2015 was 7.1% in Surgery group (n = 38) and 7.2% in Medical/Lifestyle group (n = 14), mean difference -0.10% (95% CI -0.35% to 0.15%)

variableDefinition

org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: population

description:

61 obese patients aged 25 to 55 years with T2DM

note: population

observed: Courcoulas 2015 Trial Enrollment Group

variableDefinition

org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: exposure

org/fhir/uv/ebm/StructureDefinition/variable-definition-comparator-category: no bariatric surgery

description:

Roux-en-Y Gastric Bypass, Laparoscopic Adjustable Gastric Banding vs. medical treatment (Medical Weight Management MWM)

note: exposure

observed: GroupAssignment: Bariatric Surgery vs. no bariatric surgery

variableDefinition

org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: outcome

description:

HbA1c at 36 months

note: outcome

observed: OutcomeVariable: HbA1c at 36 months

synthesisType: not applicable

studyDesign: randomized assignment

statistic

description:

mean difference -0.10% (95% CI -0.35% to 0.15%)

note: Mean HbA1c at 36 months in Courcoulas 2015 was 7.1% in Surgery group (n = 38) and 7.2% in Medical/Lifestyle group (n = 14)

statisticType: Mean Difference

quantity: -0.1 % (Details: UCUM code% = '%')

SampleSizes

-NumberOfParticipantsKnownDataCount
*6161

AttributeEstimates

-DescriptionTypeLevelRange
*

95% CI -0.35% to 0.15%

Confidence interval0.95-0.35-0.15 %