Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot - ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Example Evidence: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Cummings 2016

Active as of 2022-05-29

Generated Narrative: Evidence

Resource Evidence "47759" Version "12" Updated "2023-12-06 16:50:59+0000"

Profiles: ComparativeEvidence, SingleStudyEvidence

url: https://fevir.net/resources/Evidence/47759

identifier: FEvIR Object Identifier/47759

version: 1.0.0-ballot

name: ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Cummings_2016

title: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Cummings 2016

status: active

date: 2022-05-29 11:01:56+0000

publisher: HL7 International / Clinical Decision Support

contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss

author: Brian S. Alper:

UseContexts

-CodeValue[x]
*Evidence Communication (Details: https://fevir.net/resources/CodeSystem/179423 code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')ComparativeEvidence (Evidence Based Medicine on FHIR Implementation Guide Code System#ComparativeEvidence)
*Evidence Communication (Details: https://fevir.net/resources/CodeSystem/179423 code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')SingleStudyEvidence (Evidence Based Medicine on FHIR Implementation Guide Code System#SingleStudyEvidence)

copyright: https://creativecommons.org/licenses/by-nc-sa/4.0/

relatedArtifact

type: derived-from

label: data source

display: Figure 2C

citation: Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations [Journal Article]. Contributors: Francesco Rubino, David M Nathan, Robert H Eckel, Philip R Schauer, K George M M Alberti, Paul Z Zimmet, Stefano Del Prato, Linong Ji, Shaukat M Sadikot, William H Herman, Stephanie A Amiel, Lee M Kaplan, Gaspar Taroncher-Oldenburg, David E Cummings, Delegates of the 2nd Diabetes Surgery Summit. In: Diabetes care, PMID 27222544. Published June 2016. Available at: https://pubmed.ncbi.nlm.nih.gov/27222544/.

document

relatedArtifact

type: cite-as

citation: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Cummings 2016 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 47759. Revised 2022-05-29. Available at: https://fevir.net/resources/Evidence/47759. Computable resource at: https://fevir.net/resources/Evidence/47759.

description: Mean HbA1c at 12 months in Cummings 2016 was 6.4% in Surgery group (n = 15) and 6.9% in Medical/Lifestyle group (n = 17), mean difference -0.50% (95% CI -1.52% to 0.52%)

variableDefinition

VariableDefinitionVariableRoleCode: population

description: 32 patients aged 25 to 64 with T2DM and BMI between 30-45

note: population

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#population "population")

observed: : Cummings 2016 Trial Enrollment Group

variableDefinition

VariableDefinitionVariableRoleCode: exposure

VariableDefinitionComparatorCategory: medical treatment

description: Roux-en-Y Gastric Bypass vs. medical treatment (Intensive lifestyle and medical intervention ILMI)

note: exposure

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#exposure "exposure")

observed: EvidenceVariable/172478: GroupAssignment: Roux-en-Y gastric bypass vs. medical treatment "GroupAssignment_Roux_en_Y_gastric_bypass_vs_medical_treatment"

variableDefinition

VariableDefinitionVariableRoleCode: outcome

description: HbA1c at 12 months

note: outcome

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#measuredVariable "measured variable")

observed: EvidenceVariable/173243: OutcomeVariable: HbA1c at 12 months "OutcomeVariable_HbA1c_at_12_months"

synthesisType: not applicable (StatisticSynthesisType#NotApplicable)

studyDesign: randomized assignment (Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide#SEVCO:01003)

statistic

description: mean difference -0.50% (95% CI -1.52% to 0.52%)

note: Mean HbA1c at 12 months in Cummings 2016 was 6.4% in Surgery group (n = 15) and 6.9% in Medical/Lifestyle group (n = 17)

statisticType: Mean Difference (StatisticStatisticType#0000457)

quantity: -1 % (Details: UCUM code % = '%')

SampleSizes

-NumberOfParticipantsKnownDataCount
*3232

AttributeEstimates

-DescriptionTypeLevelRange
*95% CI -1.52% to 0.52%Confidence interval (StatisticAttribute Estimate Type#C53324)0.95-1.52-0.52 %