Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot - ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Example Evidence: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Ikramuddin 2013

Active as of 2022-05-29

Generated Narrative: Evidence

Resource Evidence "47751" Version "18" Updated "2023-12-06 17:47:29+0000"

Profiles: ComparativeEvidence, SingleStudyEvidence

url: https://fevir.net/resources/Evidence/47751

identifier: FEvIR Object Identifier/47751

version: 1.0.0-ballot

name: ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Ikramuddin_2013

title: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Ikramuddin 2013

status: active

date: 2022-05-29 11:03:23+0000

publisher: HL7 International / Clinical Decision Support

contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss

author: Brian S. Alper:

UseContexts

-CodeValue[x]
*Evidence Communication (Details: https://fevir.net/resources/CodeSystem/179423 code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')ComparativeEvidence (Evidence Based Medicine on FHIR Implementation Guide Code System#ComparativeEvidence)
*Evidence Communication (Details: https://fevir.net/resources/CodeSystem/179423 code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')SingleStudyEvidence (Evidence Based Medicine on FHIR Implementation Guide Code System#SingleStudyEvidence)

copyright: https://creativecommons.org/licenses/by-nc-sa/4.0/

relatedArtifact

type: derived-from

label: data source

display: Figure 2C

citation: Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations [Journal Article]. Contributors: Francesco Rubino, David M Nathan, Robert H Eckel, Philip R Schauer, K George M M Alberti, Paul Z Zimmet, Stefano Del Prato, Linong Ji, Shaukat M Sadikot, William H Herman, Stephanie A Amiel, Lee M Kaplan, Gaspar Taroncher-Oldenburg, David E Cummings, Delegates of the 2nd Diabetes Surgery Summit. In: Diabetes care, PMID 27222544. Published June 2016. Available at: https://pubmed.ncbi.nlm.nih.gov/27222544/.

document

relatedArtifact

type: cite-as

citation: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Ikramuddin 2013 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 47751. Revised 2022-05-29. Available at: https://fevir.net/resources/Evidence/47751. Computable resource at: https://fevir.net/resources/Evidence/47751.

description: Mean HbA1c at 12 months in Ikramuddin 2013 was 6.3 % in Surgery group (n = 57) and 7.8% in Medical/Lifestyle group (n = 19), mean difference -1.50% (95% CI -1.95% to -1.05%)

variableDefinition

VariableDefinitionVariableRoleCode: population

description: 114 patients with T2DM and BMI 30 to 39.9 and HbA1c >= 8.0

note: population

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#population "population")

observed: : Ikramuddin 2013 Trial Enrollment Group

variableDefinition

VariableDefinitionVariableRoleCode: exposure

VariableDefinitionComparatorCategory: Lifestyle-intensive medical management intervention based on the Diabetes Prevention Program and LookAHEAD trials for 2 years

description: Roux-en-Y Gastric Bypass vs. medical treatment (Lifestyle-intensive medical management intervention LS/IMM)

note: exposure

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#exposure "exposure")

observed: EvidenceVariable/172481: GroupAssignment: Roux-en-Y gastric bypass surgery vs. Lifestyle-intensive medical management intervention alone "GroupAssignment_Roux_en_Y_gastric_bypass_surgery_vs_Lifestyle_intensive_medical_management_intervention_alone"

variableDefinition

VariableDefinitionVariableRoleCode: outcome

description: HbA1c at 12 months

note: outcome

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#measuredVariable "measured variable")

observed: EvidenceVariable/173243: OutcomeVariable: HbA1c at 12 months "OutcomeVariable_HbA1c_at_12_months"

synthesisType: not applicable (StatisticSynthesisType#NotApplicable)

studyDesign: randomized assignment (Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide#SEVCO:01003)

statistic

description: mean difference -1.50% (95% CI -1.95% to -1.05%)

note: Mean HbA1c at 12 months in Ikramuddin 2013 was 6.3 % in Surgery group (n = 57) and 7.8% in Medical/Lifestyle group (n = 57)

statisticType: Mean Difference (StatisticStatisticType#0000457)

quantity: -1.5 % (Details: UCUM code % = '%')

SampleSizes

-NumberOfParticipantsKnownDataCount
*114114

AttributeEstimates

-DescriptionTypeLevelRange
*95% CI -1.95% to -1.05%Confidence interval (StatisticAttribute Estimate Type#C53324)0.95-1.95--1.05 %