Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
Active as of 2024-11-01 |
Generated Narrative: Evidence 236960
version: 61; Last updated: 2024-10-03 13:11:20+0000
Profile: ComparativeEvidence
identifier: FEvIR Object Identifier/236960, outcomeId/313958, picoId/85798, sectionId/73215, Uniform Resource Identifier (URI)/urn:oid:2.16.840.1.113883.4.642.40.44.22.62
version: 2.0.0-ballot
name: Nonfatal_myocardial_infarctionfrom_MAGICapp_313958
title: MAGIC-derived Evidence: Nonfatal myocardial infarction with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes
status: Active
date: 2024-11-01 10:20:00+0000
publisher: HL7 International / Clinical Decision Support
contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss
author: Computable Publishing®: MAGIC-to-FEvIR Converter:
Code | Value[x] |
Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence Communication | ComparativeEvidence |
copyright:
https://creativecommons.org/licenses/by-nc-sa/4.0/
Type | ResourceReference |
Part Of | MAGICapp Conversion Report: SGLT2 inhibitors and GLP-1 RA for type 2 diabetes (Identifier: FEvIR Linking Identifier/MAGIC-5288-j1Wqrn-conversion-report) |
description:
This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.
assertion:
There is no important difference between SGLT2 inhibitors and GLP-1 receptor agonists on the risk of nonfatal myocardial infarction.
variableDefinition
org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: population
description:
Adults with type 2 diabetes
note: population
variableDefinition
org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: exposure
org/fhir/uv/ebm/StructureDefinition/variable-definition-comparator-category: GLP-1 RA
description:
GroupAssignment: SGLT2 inhibitors vs. GLP-1 RA
note: exposure
variableDefinition
org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: outcome
description:
Nonfatal myocardial infarction
note: outcome
observed: Nonfatal myocardial infarction
synthesisType: SYSTEMATIC_REVIEW
studyDesign: NOTSET
statistic
description:
Risk Difference -0.7% (CI95 -2.4% to 1.1%)
statisticType: Risk Difference
quantity: -0.007
SampleSizes
NumberOfStudies NumberOfParticipants 1 463 AttributeEstimates
Type Range CI95 -0.024-0.011
statistic
description:
OR 0.95 (CI95 0.84 to 1.08)
statisticType: Odds Ratio
quantity: 0.95
SampleSizes
NumberOfStudies NumberOfParticipants 1 463 AttributeEstimates
Type Range CI95 0.84-1.08
certainty
description:
Due to serious imprecision
type: Overall certainty
rating: Moderate certainty
Subcomponents
Type Rating Risk of Bias NOTSET Inconsistency NOTSET Indirectness NOTSET Imprecision NOTSET Publication Bias NOTSET