Generated Narrative: Citation 33399

url: Citation 35243488 Bariatric surgery and cardiovascular disease: a systematic review and meta-analysis.

identifier: FEvIR Object Identifier/33399, https://pubmed.ncbi.nlm.nih.gov/35243488, Uniform Resource Identifier (URI)/urn:oid:2.16.840.1.113883.4.642.40.44.15.10

version: 2.0.0-ballot

title: 35243488 Bariatric surgery and cardiovascular disease: a systematic review and meta-analysis.

status: Active

date: 2024-11-01 10:20:00+0000

publisher: HL7 International / Clinical Decision Support

contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss

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jurisdiction: World

copyright:

approvalDate: 2022-05-24

lastReviewDate: 2022-07-24

author: Computable Publishing®: MEDLINE-to-FEvIR Converter:

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type: Citation Source

classifier: MEDLINE

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type: MEDLINE Citation Owner

classifier: National Library of Medicine, Index Section

currentState: Medline Citation Status of Medline, PubMed PublicationStatus of ppublish

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activity: PubMed Pubstatus of Received

period: ?? --> 2021-05-24

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activity: PubMed Pubstatus of Revised

period: ?? --> 2022-02-02

statusDate

activity: PubMed Pubstatus of Accepted

period: ?? --> 2022-02-03

statusDate

activity: PubMed Pubstatus of Pubmed

period: ?? --> 2022-03-05 06:00:00+0000

statusDate

activity: PubMed Pubstatus of Medline

period: ?? --> 2022-05-25 06:00:00+0000

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activity: PubMed Pubstatus of Entrez

period: ?? --> 2022-03-04 05:44:00+0000

statusDate

activity: PubMed Pubstatus of PMC release

period: ?? --> 2022-03-04

citedArtifact

identifier: https://pubmed.ncbi.nlm.nih.gov/35243488, https://www.ncbi.nlm.nih.gov/pmc//PMC9123239, https://doi.org/10.1093/eurheartj/ehac071, pii/6542137

Titles

-	Type	Language	Text
*	Primary title	English	Bariatric surgery and cardiovascular disease: a systematic review and meta-analysis.

Abstracts

-	Text	Copyright
*	AIMS: Obesity is a global health problem, associated with significant morbidity and mortality, often due to cardiovascular (CV) diseases. While bariatric surgery is increasingly performed in patients with obesity and reduces CV risk factors, its effect on CV disease is not established. We conducted a systematic review and meta-analysis to evaluate the effect of bariatric surgery on CV outcomes, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. METHODS AND RESULTS: PubMed and Embase were searched for literature until August 2021 which compared bariatric surgery patients to non-surgical controls. Outcomes of interest were all-cause and CV mortality, atrial fibrillation (AF), heart failure (HF), myocardial infarction, and stroke. We included 39 studies, all prospective or retrospective cohort studies, but randomized outcome trials were not available. Bariatric surgery was associated with a beneficial effect on all-cause mortality [pooled hazard ratio (HR) of 0.55; 95% confidence interval (CI) 0.49-0.62, P < 0.001 vs. controls], and CV mortality (HR 0.59, 95% CI 0.47-0.73, P < 0.001). In addition, bariatric surgery was also associated with a reduced incidence of HF (HR 0.50, 95% CI 0.38-0.66, P < 0.001), myocardial infarction (HR 0.58, 95% CI 0.43-0.76, P < 0.001), and stroke (HR 0.64, 95% CI 0.53-0.77, P < 0.001), while its association with AF was not statistically significant (HR 0.82, 95% CI 0.64-1.06, P = 0.12). CONCLUSION: The present systematic review and meta-analysis suggests that bariatric surgery is associated with reduced all-cause and CV mortality, and lowered incidence of several CV diseases in patients with obesity. Bariatric surgery should therefore be considered in these patients.	© The Author(s) 2022. Published by Oxford University Press on behalf of European Society of Cardiology.

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Arterburn  DE, Telem  DA, Kushner  RF, Courcoulas  AP. Benefits and risks of bariatric surgery in adults: a review. JAMA  2020;324:879–887.

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Yoshino  M, Kayser  BD, Yoshino  J, Stein  RI, Reeds  D, Eagon  JC, et al.  Effects of diet versus gastric bypass on metabolic function in diabetes. N Engl J Med  2020;383:721–732.

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Aminian  A, Zajichek  A, Tu  C, Wolski  KE, Brethauer  SA, Schauer  PR, et al.  How much weight loss is required for cardiovascular benefits? Insights from a metabolic surgery matched-cohort study. Ann Surg  2020;272:639–645.

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Schauer  PR, Bhatt  DL, Kirwan  JP, Wolski  K, Aminian  A, Brethauer  SA, et al.  Bariatric surgery versus intensive medical therapy for diabetes – 5-year outcomes. N Engl J Med  2017;376:641–651.

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Rubino  F, Nathan  DM, Eckel  RH, Schauer  PR, Alberti  KG, Zimmet  PZ, et al.  Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations. Diabetes Care  2016;39:861–877.

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classifier: is Major topic

component

type: qualifier

classifier: complications

Components

-	Type	Classifier
*	is Major topic	No

component

type: qualifier

classifier: epidemiology

Components

-	Type	Classifier
*	is Major topic	No