This structure is derived from MolecularDefinition.

Summary

to do

Mandatory: 2 elements
Prohibited: 1 element

Structures

This structure refers to these other structures:

• http://hl7.org/fhir/StructureDefinition/sequence

This indicates the differences between this profile and the base MolecularDefinition structure.

Name	Flags	Card.	Type	Description & Constraints
MolecularDefinition		0..*	MolecularDefinition	FHIR Allele Profile
type		1..1	code	Sequence type, e.g., aa, dna, or rna
location		1..1	BackboneElement	Location of this molecule
memberState		0..0
representation
extracted
startingMolecule		1..1	Reference(Molecular Definition as Sequence Profile)	Starting sequence
repeated
sequenceMotif		1..1	Reference(Molecular Definition as Sequence Profile)	The sequence that defines the repeated motif
concatenated
sequenceElement
sequence		1..1	Reference(Molecular Definition as Sequence Profile)	The Molecular Sequence corresponding to this element
relative
startingMolecule		1..1	Reference(Molecular Definition as Sequence Profile)	The Molecular Sequence that serves as the starting sequence, on which edits will be applied
edit
replacementMolecule		1..1	Reference(Molecular Definition as Sequence Profile)	The sequence that defines the replacement sequence used in the edit operation
replacedMolecule		0..1	Reference(Molecular Definition as Sequence Profile)	The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit
Documentation for this format

This provides the consolidated view (aka snapshot) of the profile after applying the changes in this profile to the base MolecularDefinition structure.

Name	Flags	Card.	Type	Description & Constraints
MolecularDefinition		0..*	MolecularDefinition	FHIR Allele Profile
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: All Languages (required): IETF language tag for a human language Additional Bindings Purpose Common Languages Starter Set
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	Unique ID for this particular resource
type	Σ	1..1	code	Sequence type, e.g., aa, dna, or rna Binding: sequence Type (required): Type of a molecule -- DNA, RNA, or amino acid sequence.
location	Σ	1..1	BackboneElement	Location of this molecule
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequenceLocation	Σ	0..1	BackboneElement	Location of this molecule in context of a sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequenceContext	Σ	1..1	Reference(MolecularDefinition)	Reference sequence
coordinateInterval	Σ	0..1	BackboneElement	Coordinate Interval for this location
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
numberingSystem	Σ	0..1	CodeableConcept	Coordinate System
start[x]	Σ	0..1		Start
startQuantity			Quantity
startRange			Range
end[x]	Σ	0..1		End
endQuantity			Quantity
endRange			Range
strand		0..1	CodeableConcept	Forward or Reverse
cytobandLocation	Σ	0..1	BackboneElement	Location of this molecule in context of a cytoband
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
genomeAssembly	Σ	1..1	BackboneElement	Reference Genome
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
organism		0..1	CodeableConcept	Species of the organism
build		0..1	CodeableConcept	Build number
accession		0..1	CodeableConcept	Accession
description[x]		0..1		Genome assemble description
descriptionMarkdown			markdown
descriptionString			string
cytobandInterval	Σ	1..1	BackboneElement	Cytoband Interval
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
chromosome	Σ	1..1	CodeableConcept	Chromosome
startCytoband	Σ	0..1	BackboneElement	Start
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
arm[x]		0..1		Arm
armCode			code
armString			string
region[x]		0..1		Region
regionCode			code
regionString			string
band[x]		0..1		Band
bandCode			code
bandString			string
subBand[x]		0..1		Sub-band
subBandCode			code
subBandString			string
endCytoband	Σ	0..1	BackboneElement	End
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
arm[x]		0..1		Arm
armCode			code
armString			string
region[x]		0..1		Region
regionCode			code
regionString			string
band[x]		0..1		Band
bandCode			code
bandString			string
subBand[x]		0..1		SuBand
subBandCode			code
subBandString			string
featureLocation	Σ	0..*	BackboneElement	Location in context of a feature
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
geneId	Σ	0..*	CodeableConcept	Gene Id
representation	Σ	0..*	BackboneElement	Representation
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
focus	Σ	0..1	CodeableConcept	The focus of the representation
code	Σ	0..*	CodeableConcept	A code of the representation
literal	Σ	0..1	BackboneElement	A literal representation
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
encoding	Σ	0..1	CodeableConcept	The encoding used for the expression of the primary sequence
value	Σ	1..1	string	The primary (linear) sequence, expressed as a literal string
resolvable	Σ	0..1	Attachment	A resolvable representation of a molecule that optionally contains formatting in addition to the specification of the primary sequence itself
extracted	Σ	0..1	BackboneElement	A Molecular Sequence that is represented as an extracted portion of a different Molecular Sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
startingMolecule	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	Starting sequence
start	Σ	1..1	integer	The start coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted
end	Σ	1..1	integer	The end coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted
coordinateSystem	Σ	1..1	CodeableConcept	The coordinate system used to define the interval that defines the subsequence to be extracted. Coordinate systems are usually 0- or 1-based
reverseComplement	Σ	0..1	boolean	A flag that indicates whether the extracted sequence should be reverse complemented
repeated	Σ	0..1	BackboneElement	A Molecular Sequence that is represented as a repeated sequence motif
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequenceMotif	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	The sequence that defines the repeated motif
copyCount	Σ	1..1	integer	The number of repeats (copies) of the sequence motif
concatenated	Σ	0..1	BackboneElement	A Molecular Sequence that is represented as an ordered concatenation of two or more Molecular Sequences
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequenceElement	Σ	1..*	BackboneElement	One element of a concatenated Molecular Sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	The Molecular Sequence corresponding to this element
ordinalIndex	Σ	1..1	integer	The ordinal position of this sequence element within the concatenated Molecular Sequence
relative	Σ	0..1	BackboneElement	A Molecular Definition that is represented as an ordered series of edits on a specified starting sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
startingMolecule	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	The Molecular Sequence that serves as the starting sequence, on which edits will be applied
edit	Σ	0..*	BackboneElement	An edit (change) made to a sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
editOrder		0..1	integer	The order of this edit, relative to other edits on the starting sequence
coordinateSystem	Σ	1..1	CodeableConcept	The coordinate system used to define the edited intervals on the starting sequence. Coordinate systems are usually 0- or 1-based Binding: Genomic coordinate system. (extensible): Genomic coordinate system.
start	Σ	1..1	integer	The start coordinate of the interval that will be edited
end	Σ	1..1	integer	The end coordinate of the interval that will be edited
replacementMolecule	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	The sequence that defines the replacement sequence used in the edit operation
replacedMolecule	Σ	0..1	Reference(Molecular Definition as Sequence Profile)	The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit
Documentation for this format

<!-- MolecularDefinitionAllele -->

<MolecularDefinition xmlns="http://hl7.org/fhir"
>
  <!-- from Element: extension -->
 <id value="[id]"/><!-- 0..1 Logical id of this artifact -->
 <meta><!-- I 0..1 Meta Metadata about the resource --></meta>
 <implicitRules value="[uri]"/><!-- I 0..1 A set of rules under which this content was created -->
 <language value="[code]"/><!-- I 0..1 Language of the resource content   -->
 <text><!-- I 0..1 Narrative 
     Text summary of the resource, for human interpretation --></text>
 <contained><!-- 0..* Resource 
     Contained, inline Resources --></contained>
 <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored  --></modifierExtension>
 <identifier><!-- I 0..* Identifier 
     Unique ID for this particular resource --></identifier>
 <type value="[code]"/><!-- I 1..1 Sequence type, e.g., aa, dna, or rna   -->
 <location> I 1..1 BackboneElement  <!-- I 1..1 Location of this molecule -->
  <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
  <sequenceLocation> I 0..1 BackboneElement  <!-- I 0..1 Location of this molecule in context of a sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceContext><!-- I 1..1 
     Reference(MolecularDefinition) Reference sequence --></sequenceContext>
   <coordinateInterval> I 0..1 
     BackboneElement  <!-- I 0..1 Coordinate Interval for this location -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <numberingSystem><!-- I 0..1 
      CodeableConcept 
        Coordinate System --></numberingSystem>
    <start[x]><!-- I 0..1 
      Quantity|Range 
        Start --></start[x]>
    <end[x]><!-- I 0..1 
      Quantity|Range End --></end[x]>
   </coordinateInterval>
   <strand><!-- I 0..1 
     CodeableConcept Forward or Reverse --></strand>
  </sequenceLocation>
  <cytobandLocation> I 0..1 BackboneElement  <!-- I 0..1 Location of this molecule in context of a cytoband -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <genomeAssembly> I 1..1 
     BackboneElement  <!-- I 1..1 Reference Genome -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <organism><!-- I 0..1 
      CodeableConcept 
        Species of the organism --></organism>
    <build><!-- I 0..1 
      CodeableConcept 
        Build number --></build>
    <accession><!-- I 0..1 
      CodeableConcept 
        Accession --></accession>
    <description[x]><!-- I 0..1 
      markdown|string 
        Genome assemble description --></description[x]>
   </genomeAssembly>
   <cytobandInterval> I 1..1 
     BackboneElement  <!-- I 1..1 Cytoband Interval -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <chromosome><!-- I 1..1 
      CodeableConcept 
        Chromosome --></chromosome>
    <startCytoband> I 0..1 
      BackboneElement  <!-- I 0..1 Start -->
     <modifierExtension><!-- I 0..* 
       Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
     <arm[x]><!-- I 0..1 
       code|string 
         Arm --></arm[x]>
     <region[x]><!-- I 0..1 
       code|string 
         Region --></region[x]>
     <band[x]><!-- I 0..1 
       code|string 
         Band --></band[x]>
     <subBand[x]><!-- I 0..1 
       code|string 
         Sub-band --></subBand[x]>
    </startCytoband>
    <endCytoband> I 0..1 
      BackboneElement  <!-- I 0..1 End -->
     <modifierExtension><!-- I 0..* 
       Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
     <arm[x]><!-- I 0..1 
       code|string 
         Arm --></arm[x]>
     <region[x]><!-- I 0..1 
       code|string 
         Region --></region[x]>
     <band[x]><!-- I 0..1 
       code|string 
         Band --></band[x]>
     <subBand[x]><!-- I 0..1 
       code|string 
         SuBand --></subBand[x]>
    </endCytoband>
   </cytobandInterval>
  </cytobandLocation>
  <featureLocation> I 0..* BackboneElement  <!-- I 0..* Location in context of a feature -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <geneId><!-- I 0..* 
     CodeableConcept Gene Id --></geneId>
  </featureLocation>
 </location>
 <memberState><!-- I 0..0 Reference(MolecularDefinition) Member --></memberState>
 <representation> I 0..* BackboneElement  <!-- I 0..* Representation -->
  <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
  <focus><!-- I 0..1 CodeableConcept 
      The focus of the representation --></focus>
  <code><!-- I 0..* CodeableConcept 
      A code of the representation --></code>
  <literal> I 0..1 BackboneElement  <!-- I 0..1 A literal representation -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <encoding><!-- I 0..1 
     CodeableConcept 
       The encoding used for the expression of the primary sequence --></encoding>
   <value value="[string]"/><!-- I 1..1 
       The primary (linear) sequence, expressed as a literal string -->
  </literal>
  <resolvable><!-- I 0..1 Attachment 
      A resolvable representation of a molecule that optionally contains formatting in addition to the specification of the primary sequence itself --></resolvable>
  <extracted> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as an extracted portion of a different Molecular Sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <startingMolecule><!-- I 1..1 
     Reference(MolecularDefinitionSequence) Starting sequence --></startingMolecule>
   <start value="[integer]"/><!-- I 1..1 
       The start coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted -->
   <end value="[integer]"/><!-- I 1..1 
       The end coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted -->
   <coordinateSystem><!-- I 1..1 
     CodeableConcept 
       The coordinate system used to define the interval that defines the subsequence to be extracted. Coordinate systems are usually 0- or 1-based --></coordinateSystem>
   <reverseComplement value="[boolean]"/><!-- I 0..1 
       A flag that indicates whether the extracted sequence should be reverse complemented -->
  </extracted>
  <repeated> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as a repeated sequence motif -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceMotif><!-- I 1..1 
     Reference(MolecularDefinitionSequence) 
       The sequence that defines the repeated motif --></sequenceMotif>
   <copyCount value="[integer]"/><!-- I 1..1 
       The number of repeats (copies) of the sequence motif -->
  </repeated>
  <concatenated> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as an ordered concatenation of two or more Molecular Sequences -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceElement> I 1..* 
     BackboneElement  <!-- I 1..* One element of a concatenated Molecular Sequence -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <sequence><!-- I 1..1 
      Reference(MolecularDefinitionSequence) 
        The Molecular Sequence corresponding to this element --></sequence>
    <ordinalIndex value="[integer]"/><!-- I 1..1 
        The ordinal position of this sequence element within the concatenated Molecular Sequence -->
   </sequenceElement>
  </concatenated>
  <relative> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Definition that is represented as an ordered series of edits on a specified starting sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <startingMolecule><!-- I 1..1 
     Reference(MolecularDefinitionSequence) 
       The Molecular Sequence that serves as the starting sequence, on which edits will be applied --></startingMolecule>
   <edit> I 0..* BackboneElement  <!-- I 0..* An edit (change) made to a sequence -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <editOrder value="[integer]"/><!-- I 0..1 
        The order of this edit, relative to other edits on the starting sequence -->
    <coordinateSystem><!-- I 1..1 
      CodeableConcept The coordinate system used to define the edited intervals on the starting sequence. Coordinate systems are usually 0- or 1-based    --></coordinateSystem>
    <start value="[integer]"/><!-- I 1..1 
        The start coordinate of the interval that will be edited -->
    <end value="[integer]"/><!-- I 1..1 
        The end coordinate of the interval that will be edited -->
    <replacementMolecule><!-- I 1..1 
      Reference(MolecularDefinitionSequence) 
        The sequence that defines the replacement sequence used in the edit operation --></replacementMolecule>
    <replacedMolecule><!-- I 0..1 
      Reference(MolecularDefinitionSequence) 
        The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit --></replacedMolecule>
   </edit>
  </relative>
 </representation>
</MolecularDefinition>

{ // MolecularDefinitionAllele
  // from Element: extension
    "meta" : { Meta }, // IMetadata about the resource
    "implicitRules" : "<uri>", // IA set of rules under which this content was created
    "language" : "<code>", // ILanguage of the resource content
    "text" : { Narrative }, // IText summary of the resource, for human interpretation
    "contained" : [{ Resource }], //Contained, inline Resources
    "modifierExtension" : [{ Extension }], // IExtensions that cannot be ignored
    "identifier" : [{ Identifier }], // IUnique ID for this particular resource
    "type" : "<code>", // I R! Sequence type, e.g., aa, dna, or rna
    "location" : { BackboneElement }, // I R! Location of this molecule
    "representation" : [{ BackboneElement }] // IRepresentation
  }

Summary

to do

Mandatory: 2 elements
Prohibited: 1 element

Structures

This structure refers to these other structures:

• http://hl7.org/fhir/StructureDefinition/sequence

This provides the consolidated view (aka snapshot) of the profile after applying the changes in this profile to the base MolecularDefinition structure.

Name	Flags	Card.	Type	Description & Constraints
MolecularDefinition		0..*	MolecularDefinition	FHIR Allele Profile
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: All Languages (required): IETF language tag for a human language Additional Bindings Purpose Common Languages Starter Set
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	Unique ID for this particular resource
type	Σ	1..1	code	Sequence type, e.g., aa, dna, or rna Binding: sequence Type (required): Type of a molecule -- DNA, RNA, or amino acid sequence.
location	Σ	1..1	BackboneElement	Location of this molecule
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequenceLocation	Σ	0..1	BackboneElement	Location of this molecule in context of a sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequenceContext	Σ	1..1	Reference(MolecularDefinition)	Reference sequence
coordinateInterval	Σ	0..1	BackboneElement	Coordinate Interval for this location
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
numberingSystem	Σ	0..1	CodeableConcept	Coordinate System
start[x]	Σ	0..1		Start
startQuantity			Quantity
startRange			Range
end[x]	Σ	0..1		End
endQuantity			Quantity
endRange			Range
strand		0..1	CodeableConcept	Forward or Reverse
cytobandLocation	Σ	0..1	BackboneElement	Location of this molecule in context of a cytoband
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
genomeAssembly	Σ	1..1	BackboneElement	Reference Genome
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
organism		0..1	CodeableConcept	Species of the organism
build		0..1	CodeableConcept	Build number
accession		0..1	CodeableConcept	Accession
description[x]		0..1		Genome assemble description
descriptionMarkdown			markdown
descriptionString			string
cytobandInterval	Σ	1..1	BackboneElement	Cytoband Interval
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
chromosome	Σ	1..1	CodeableConcept	Chromosome
startCytoband	Σ	0..1	BackboneElement	Start
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
arm[x]		0..1		Arm
armCode			code
armString			string
region[x]		0..1		Region
regionCode			code
regionString			string
band[x]		0..1		Band
bandCode			code
bandString			string
subBand[x]		0..1		Sub-band
subBandCode			code
subBandString			string
endCytoband	Σ	0..1	BackboneElement	End
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
arm[x]		0..1		Arm
armCode			code
armString			string
region[x]		0..1		Region
regionCode			code
regionString			string
band[x]		0..1		Band
bandCode			code
bandString			string
subBand[x]		0..1		SuBand
subBandCode			code
subBandString			string
featureLocation	Σ	0..*	BackboneElement	Location in context of a feature
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
geneId	Σ	0..*	CodeableConcept	Gene Id
representation	Σ	0..*	BackboneElement	Representation
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
focus	Σ	0..1	CodeableConcept	The focus of the representation
code	Σ	0..*	CodeableConcept	A code of the representation
literal	Σ	0..1	BackboneElement	A literal representation
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
encoding	Σ	0..1	CodeableConcept	The encoding used for the expression of the primary sequence
value	Σ	1..1	string	The primary (linear) sequence, expressed as a literal string
resolvable	Σ	0..1	Attachment	A resolvable representation of a molecule that optionally contains formatting in addition to the specification of the primary sequence itself
extracted	Σ	0..1	BackboneElement	A Molecular Sequence that is represented as an extracted portion of a different Molecular Sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
startingMolecule	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	Starting sequence
start	Σ	1..1	integer	The start coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted
end	Σ	1..1	integer	The end coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted
coordinateSystem	Σ	1..1	CodeableConcept	The coordinate system used to define the interval that defines the subsequence to be extracted. Coordinate systems are usually 0- or 1-based
reverseComplement	Σ	0..1	boolean	A flag that indicates whether the extracted sequence should be reverse complemented
repeated	Σ	0..1	BackboneElement	A Molecular Sequence that is represented as a repeated sequence motif
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequenceMotif	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	The sequence that defines the repeated motif
copyCount	Σ	1..1	integer	The number of repeats (copies) of the sequence motif
concatenated	Σ	0..1	BackboneElement	A Molecular Sequence that is represented as an ordered concatenation of two or more Molecular Sequences
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequenceElement	Σ	1..*	BackboneElement	One element of a concatenated Molecular Sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	The Molecular Sequence corresponding to this element
ordinalIndex	Σ	1..1	integer	The ordinal position of this sequence element within the concatenated Molecular Sequence
relative	Σ	0..1	BackboneElement	A Molecular Definition that is represented as an ordered series of edits on a specified starting sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
startingMolecule	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	The Molecular Sequence that serves as the starting sequence, on which edits will be applied
edit	Σ	0..*	BackboneElement	An edit (change) made to a sequence
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
editOrder		0..1	integer	The order of this edit, relative to other edits on the starting sequence
coordinateSystem	Σ	1..1	CodeableConcept	The coordinate system used to define the edited intervals on the starting sequence. Coordinate systems are usually 0- or 1-based Binding: Genomic coordinate system. (extensible): Genomic coordinate system.
start	Σ	1..1	integer	The start coordinate of the interval that will be edited
end	Σ	1..1	integer	The end coordinate of the interval that will be edited
replacementMolecule	Σ	1..1	Reference(Molecular Definition as Sequence Profile)	The sequence that defines the replacement sequence used in the edit operation
replacedMolecule	Σ	0..1	Reference(Molecular Definition as Sequence Profile)	The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit
Documentation for this format

<!-- MolecularDefinitionAllele -->

<MolecularDefinition xmlns="http://hl7.org/fhir"
>
  <!-- from Element: extension -->
 <id value="[id]"/><!-- 0..1 Logical id of this artifact -->
 <meta><!-- I 0..1 Meta Metadata about the resource --></meta>
 <implicitRules value="[uri]"/><!-- I 0..1 A set of rules under which this content was created -->
 <language value="[code]"/><!-- I 0..1 Language of the resource content   -->
 <text><!-- I 0..1 Narrative 
     Text summary of the resource, for human interpretation --></text>
 <contained><!-- 0..* Resource 
     Contained, inline Resources --></contained>
 <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored  --></modifierExtension>
 <identifier><!-- I 0..* Identifier 
     Unique ID for this particular resource --></identifier>
 <type value="[code]"/><!-- I 1..1 Sequence type, e.g., aa, dna, or rna   -->
 <location> I 1..1 BackboneElement  <!-- I 1..1 Location of this molecule -->
  <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
  <sequenceLocation> I 0..1 BackboneElement  <!-- I 0..1 Location of this molecule in context of a sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceContext><!-- I 1..1 
     Reference(MolecularDefinition) Reference sequence --></sequenceContext>
   <coordinateInterval> I 0..1 
     BackboneElement  <!-- I 0..1 Coordinate Interval for this location -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <numberingSystem><!-- I 0..1 
      CodeableConcept 
        Coordinate System --></numberingSystem>
    <start[x]><!-- I 0..1 
      Quantity|Range 
        Start --></start[x]>
    <end[x]><!-- I 0..1 
      Quantity|Range End --></end[x]>
   </coordinateInterval>
   <strand><!-- I 0..1 
     CodeableConcept Forward or Reverse --></strand>
  </sequenceLocation>
  <cytobandLocation> I 0..1 BackboneElement  <!-- I 0..1 Location of this molecule in context of a cytoband -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <genomeAssembly> I 1..1 
     BackboneElement  <!-- I 1..1 Reference Genome -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <organism><!-- I 0..1 
      CodeableConcept 
        Species of the organism --></organism>
    <build><!-- I 0..1 
      CodeableConcept 
        Build number --></build>
    <accession><!-- I 0..1 
      CodeableConcept 
        Accession --></accession>
    <description[x]><!-- I 0..1 
      markdown|string 
        Genome assemble description --></description[x]>
   </genomeAssembly>
   <cytobandInterval> I 1..1 
     BackboneElement  <!-- I 1..1 Cytoband Interval -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <chromosome><!-- I 1..1 
      CodeableConcept 
        Chromosome --></chromosome>
    <startCytoband> I 0..1 
      BackboneElement  <!-- I 0..1 Start -->
     <modifierExtension><!-- I 0..* 
       Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
     <arm[x]><!-- I 0..1 
       code|string 
         Arm --></arm[x]>
     <region[x]><!-- I 0..1 
       code|string 
         Region --></region[x]>
     <band[x]><!-- I 0..1 
       code|string 
         Band --></band[x]>
     <subBand[x]><!-- I 0..1 
       code|string 
         Sub-band --></subBand[x]>
    </startCytoband>
    <endCytoband> I 0..1 
      BackboneElement  <!-- I 0..1 End -->
     <modifierExtension><!-- I 0..* 
       Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
     <arm[x]><!-- I 0..1 
       code|string 
         Arm --></arm[x]>
     <region[x]><!-- I 0..1 
       code|string 
         Region --></region[x]>
     <band[x]><!-- I 0..1 
       code|string 
         Band --></band[x]>
     <subBand[x]><!-- I 0..1 
       code|string 
         SuBand --></subBand[x]>
    </endCytoband>
   </cytobandInterval>
  </cytobandLocation>
  <featureLocation> I 0..* BackboneElement  <!-- I 0..* Location in context of a feature -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <geneId><!-- I 0..* 
     CodeableConcept Gene Id --></geneId>
  </featureLocation>
 </location>
 <memberState><!-- I 0..0 Reference(MolecularDefinition) Member --></memberState>
 <representation> I 0..* BackboneElement  <!-- I 0..* Representation -->
  <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
  <focus><!-- I 0..1 CodeableConcept 
      The focus of the representation --></focus>
  <code><!-- I 0..* CodeableConcept 
      A code of the representation --></code>
  <literal> I 0..1 BackboneElement  <!-- I 0..1 A literal representation -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <encoding><!-- I 0..1 
     CodeableConcept 
       The encoding used for the expression of the primary sequence --></encoding>
   <value value="[string]"/><!-- I 1..1 
       The primary (linear) sequence, expressed as a literal string -->
  </literal>
  <resolvable><!-- I 0..1 Attachment 
      A resolvable representation of a molecule that optionally contains formatting in addition to the specification of the primary sequence itself --></resolvable>
  <extracted> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as an extracted portion of a different Molecular Sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <startingMolecule><!-- I 1..1 
     Reference(MolecularDefinitionSequence) Starting sequence --></startingMolecule>
   <start value="[integer]"/><!-- I 1..1 
       The start coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted -->
   <end value="[integer]"/><!-- I 1..1 
       The end coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted -->
   <coordinateSystem><!-- I 1..1 
     CodeableConcept 
       The coordinate system used to define the interval that defines the subsequence to be extracted. Coordinate systems are usually 0- or 1-based --></coordinateSystem>
   <reverseComplement value="[boolean]"/><!-- I 0..1 
       A flag that indicates whether the extracted sequence should be reverse complemented -->
  </extracted>
  <repeated> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as a repeated sequence motif -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceMotif><!-- I 1..1 
     Reference(MolecularDefinitionSequence) 
       The sequence that defines the repeated motif --></sequenceMotif>
   <copyCount value="[integer]"/><!-- I 1..1 
       The number of repeats (copies) of the sequence motif -->
  </repeated>
  <concatenated> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as an ordered concatenation of two or more Molecular Sequences -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceElement> I 1..* 
     BackboneElement  <!-- I 1..* One element of a concatenated Molecular Sequence -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <sequence><!-- I 1..1 
      Reference(MolecularDefinitionSequence) 
        The Molecular Sequence corresponding to this element --></sequence>
    <ordinalIndex value="[integer]"/><!-- I 1..1 
        The ordinal position of this sequence element within the concatenated Molecular Sequence -->
   </sequenceElement>
  </concatenated>
  <relative> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Definition that is represented as an ordered series of edits on a specified starting sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <startingMolecule><!-- I 1..1 
     Reference(MolecularDefinitionSequence) 
       The Molecular Sequence that serves as the starting sequence, on which edits will be applied --></startingMolecule>
   <edit> I 0..* BackboneElement  <!-- I 0..* An edit (change) made to a sequence -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <editOrder value="[integer]"/><!-- I 0..1 
        The order of this edit, relative to other edits on the starting sequence -->
    <coordinateSystem><!-- I 1..1 
      CodeableConcept The coordinate system used to define the edited intervals on the starting sequence. Coordinate systems are usually 0- or 1-based    --></coordinateSystem>
    <start value="[integer]"/><!-- I 1..1 
        The start coordinate of the interval that will be edited -->
    <end value="[integer]"/><!-- I 1..1 
        The end coordinate of the interval that will be edited -->
    <replacementMolecule><!-- I 1..1 
      Reference(MolecularDefinitionSequence) 
        The sequence that defines the replacement sequence used in the edit operation --></replacementMolecule>
    <replacedMolecule><!-- I 0..1 
      Reference(MolecularDefinitionSequence) 
        The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit --></replacedMolecule>
   </edit>
  </relative>
 </representation>
</MolecularDefinition>

{ // MolecularDefinitionAllele
  // from Element: extension
    "meta" : { Meta }, // IMetadata about the resource
    "implicitRules" : "<uri>", // IA set of rules under which this content was created
    "language" : "<code>", // ILanguage of the resource content
    "text" : { Narrative }, // IText summary of the resource, for human interpretation
    "contained" : [{ Resource }], //Contained, inline Resources
    "modifierExtension" : [{ Extension }], // IExtensions that cannot be ignored
    "identifier" : [{ Identifier }], // IUnique ID for this particular resource
    "type" : "<code>", // I R! Sequence type, e.g., aa, dna, or rna
    "location" : { BackboneElement }, // I R! Location of this molecule
    "representation" : [{ BackboneElement }] // IRepresentation
  }