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Example Ingredient/example (XML)

Biomedical Research and Regulation Work GroupMaturity Level: N/AStandards Status: InformativeCompartments: No defined compartments

Raw XML (canonical form + also see XML Format Specification)

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Example of an inhaler ingredient, showing multiple strength measurements (id = "example")

<?xml version="1.0" encoding="UTF-8"?>

<Ingredient xmlns="http://hl7.org/fhir">
  <id value="example"/> 
  <text> <status value="generated"/> <div xmlns="http://www.w3.org/1999/xhtml"><p> <b> Generated Narrative: Ingredient</b> <a name="example"> </a> </p> <div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border:
       1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Ingredient &quot;example&quot; </p> </div> <p> <b> status</b> : active</p> <p> <b> role</b> : ActiveBase <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (ingredientRole#ActiveBase)</span> </p> <h3> Manufacturers</h3> <table class="grid"><tr> <td style="display: none">-</td> <td> <b> Manufacturer</b> </td> </tr> <tr> <td style="display: none">*</td> <td> <a href="broken-link.html">Organization/example</a> </td> </tr> </table> <blockquote> <p> <b> substance</b> </p> <h3> Codes</h3> <table class="grid"><tr> <td style="display: none">-</td> <td> <b> Concept</b> </td> </tr> <tr> <td style="display: none">*</td> <td> Wizzohaler <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (substance#Wizzohaler)</span> </td> </tr> </table> <blockquote> <p> <b> strength</b> </p> <p> <b> presentation</b> : 730 mcg<span style="background: LightGoldenRodYellow"> (Details: UCUM code ug = 'ug')</span> /1 delivered dose<span style="background: LightGoldenRodYellow"> (Details: UCUM code {delivered dose} = '{delivered dose}')</span> </p> <p> <b> measurementPoint</b> : 2cm</p> </blockquote> <blockquote> <p> <b> strength</b> </p> <p> <b> presentation</b> : 460 mcg<span style="background: LightGoldenRodYellow"> (Details: UCUM code ug = 'ug')</span> /1 delivered dose<span style="background: LightGoldenRodYellow"> (Details: UCUM code {delivered dose} = '{delivered dose}')</span> </p> <p> <b> measurementPoint</b> : 5cm</p> </blockquote> </blockquote> </div> </text> <status value="active"/>  
  <role> 
    <coding> 
      <system value="http://ema.europa.eu/example/ingredientRole"/> 
      <code value="ActiveBase"/> 
    </coding> 
  </role> 
  <manufacturer> 
    <manufacturer> 
      <reference value="Organization/example"/> 
    </manufacturer> 
  </manufacturer> 
  <substance> 
    <code> 
      <concept> 
      <coding> 
        <system value="http://ema.europa.eu/example/substance"/> 
        <code value="Wizzohaler"/> 
      </coding> 
      </concept> 
    </code> 
        <!--    A single drug only has a single strength (amount of active ingredient).
         However it can be measured in different ways, giving rise to different values
     of what is basically the same underlying strength.
         In these cases the "strength" attribute can repeat.
         This is common with inhalers, where the strength is the amount of ingredient
     found in a spray or puff, but which differs at
         different distances from the nozzle. The effective strength is therefore
     different when the inhaler is used with a spacer device, 
         which changes the distance. Different countries may also chose to measure
     at different standard distances.
         This is a separate concept to presentation vs. concentration strength (which
     are two ways of expressing the same numeric value).
         Concentration strength could be in the example below, in each "strength",
     but is omitted for clarity.
         All these are different from reference strength (a strength in terms of
     a different substance). 
       -->
    <strength> 
      <presentationRatio> 
        <numerator> 
          <value value="730"/> 
          <unit value="mcg"/> 
          <system value="http://unitsofmeasure.org"/>  
          <code value="ug"/> 
        </numerator> 
        <denominator> 
          <value value="1"/> 
          <unit value="delivered dose"/> 
          <system value="http://unitsofmeasure.org"/>  
          <code value="{delivered dose}"/> 
        </denominator> 
      </presentationRatio> 
      <measurementPoint value="2cm"/> 
    </strength> 
        <!--    show a different strength value for the same ingredient, measured at a different
     distance    -->
    <strength> 
      <presentationRatio> 
        <numerator> 
          <value value="460"/> 
          <unit value="mcg"/> 
          <system value="http://unitsofmeasure.org"/>  
          <code value="ug"/> 
        </numerator> 
        <denominator> 
          <value value="1"/> 
          <unit value="delivered dose"/> 
          <system value="http://unitsofmeasure.org"/>  
          <code value="{delivered dose}"/> 
        </denominator> 
      </presentationRatio> 
      <measurementPoint value="5cm"/> 
    </strength> 
  </substance> 
</Ingredient> 

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.