Uzbekistan Core AdverseEvent profile, used to represent an adverse event that may be associated with unintended consequences for a patient or research participant.

UZ Core AdverseEvent records an adverse event such as a post-immunization reaction on the Digital Health Platform. It references the suspected entity that may have caused it - for a vaccine reaction this is the Immunization - and it may be accompanied by an Observation or Condition describing the reaction itself. It identifies the Patient affected and the Practitioner who recorded it. The event can be an actual harm or an intercepted near-miss.

Mandatory and Must Support data elements

The elements below must always be present (mandatory) or must be supported when the data is available (Must Support) - not all are required, but your system must populate each Must Support element when it has the data and process it on receipt. This is the human-readable summary; the formal views below give the exact cardinalities, types, and terminology bindings.

Each UZ Core AdverseEvent Must Have

This profile adds no mandatory cardinality of its own. The required elements are inherited from the base resource: the status of the record (1..1), the actuality - actual harm versus a potential near-miss (1..1) - and the subject the event happened to (1..1). In practice you will also always populate the suspect entity (see Must Support below).

Each UZ Core AdverseEvent Must Support

• an identifier, the status of the record, and the actuality (actual harm versus a potential near-miss);
• the subject the event happened to, the encounter, and the occurrence (a date/time, period, or schedule);
• when the event was detected and its recorded date;
• the resulting effect - the Condition or Observation the event caused - and the location;
• the seriousness and outcome;
• the recorder, and the participant (their function and actor);
• the suspect entity - the instance suspected of causing the event, which for a post-immunization reaction is the Immunization;
• notes.

For a post-immunization reaction, point the suspect entity at the Immunization and use resulting effect to link the Condition or Observation that describes the reaction.

Building the JSON, step by step

The examples below go from the smallest instance the server will accept to a full adverse-event record. Copy one and adapt it - every value shown validates against this profile. The complete reference instances are linked at the bottom of the page (fatal anaphylaxis, averted medication error).

The smallest AdverseEvent you should send

The base resource requires the status of the record, the actuality (was it an actual harm or a potential near-miss?), and the subject it happened to; an adverse event is only meaningful when you also add the suspectEntity thought to have caused it. Note that status and actuality are plain codes, not CodeableConcept - send the bare string. Every UZ Core resource must also name the profile it claims to conform to in meta.profile:

{
  "resourceType": "AdverseEvent",
  "meta": { "profile": ["https://dhp.uz/fhir/core/StructureDefinition/uz-core-adverse-event"] },
  "status": "in-progress",
  "actuality": "potential",
  "subject": { "reference": "Patient/example-salim" },
  "suspectEntity": [
    { "instanceReference": { "reference": "Medication/example-prednisone" } }
  ]
}

status (registered, in-progress, completed …) and actuality (actual / potential) each use a required binding - the value must come from the bound value set. suspectEntity.instance[x] is the instance suspected of causing the event; here a Medication, but for a post-immunization reaction it is the Immunization, and it may also be a Procedure, Substance, Device, or MedicationAdministration. It is a plain Reference, so instanceReference holds { "reference": "Type/id" } directly.

A realistic actual adverse event

For a real event that reached the patient, fill in when it happened (occurrenceDateTime), when it was detected, the recordedDate, the encounter and location, the resultingEffect (the Condition or Observation the event caused), the seriousness and outcome, the recorder, and the participant who reported it:

{
  "resourceType": "AdverseEvent",
  "meta": { "profile": [ "https://dhp.uz/fhir/core/StructureDefinition/uz-core-adverse-event" ] },
  "status": "completed",
  "actuality": "actual",
  "subject": { "reference": "Patient/example-david" },
  "encounter": { "reference": "Encounter/example-encounter" },
  "occurrenceDateTime": "2026-04-30T10:30:00+05:00",
  "detected": "2026-04-30T10:45:00+05:00",
  "recordedDate": "2026-04-30T11:15:00+05:00",
  "resultingEffect": [ { "reference": "Condition/example-anaphylaxis" } ],
  "location": { "reference": "Location/example-location" },
  "seriousness": {
    "coding": [
      {
        "system": "http://terminology.hl7.org/CodeSystem/adverse-event-seriousness",
        "code": "serious",
        "display": "Serious"
      }
    ]
  },
  "outcome": [
    {
      "coding": [
        {
          "system": "http://snomed.info/sct",
          "code": "405535005",
          "display": "Adverse incident resulting in death"
        }
      ]
    }
  ],
  "recorder": { "reference": "Practitioner/example-practitioner" },
  "participant": [
    {
      "function": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/v3-ParticipationType",
            "code": "AUT",
            "display": "author (originator)"
          }
        ]
      },
      "actor": { "reference": "Practitioner/example-practitioner" }
    }
  ],
  "suspectEntity": [ { "instanceReference": { "reference": "Medication/example-amoxicillin" } } ],
  "note": [
    {
      "text": "Patient developed anaphylaxis shortly after amoxicillin administration and died despite resuscitation efforts."
    }
  ]
}

Unlike seriousness and outcome, which are CodeableConcept (here outcome uses SNOMED CT, seriousness the HL7 seriousness code system), resultingEffect, subject, encounter, location, recorder, and participant.actor are all plain References - { "reference": "Type/id" }, with no extra nesting. participant.function carries why that person was involved (here AUT, the author who recorded it).

When it is a near-miss, not actual harm

An intercepted event that never reached the patient is recorded the same way, but with actuality set to potential. There is no resultingEffect (nothing happened to the patient) and outcome is omitted; use note to explain how it was caught. The suspectEntity still points at what would have caused the harm:

{
  "resourceType": "AdverseEvent",
  "meta": { "profile": [ "https://dhp.uz/fhir/core/StructureDefinition/uz-core-adverse-event" ] },
  "status": "in-progress",
  "actuality": "potential",
  "subject": { "reference": "Patient/example-salim" },
  "encounter": { "reference": "Encounter/example-encounter" },
  "occurrenceDateTime": "2026-04-30T10:30:00+05:00",
  "detected": "2026-04-30T10:35:00+05:00",
  "recordedDate": "2026-04-30T11:15:00+05:00",
  "location": { "reference": "Location/example-location-1" },
  "seriousness": {
    "coding": [
      {
        "system": "http://terminology.hl7.org/CodeSystem/adverse-event-seriousness",
        "code": "serious",
        "display": "Serious"
      }
    ]
  },
  "recorder": { "reference": "Practitioner/example-practitioner" },
  "suspectEntity": [ { "instanceReference": { "reference": "Medication/example-prednisone" } } ],
  "note": [
    {
      "text": "Prednisone ordered despite a documented contraindication; pharmacy intercepted it before it reached the patient."
    }
  ]
}

A near-miss is still worth recording: the seriousness reflects how bad it would have been, and detected captures when the safety net caught it. See Missing & suppressed data for when to leave an element out versus mark it absent.

For example API calls and a sample payload, see the Quick Start at the bottom of this page.

• Key Elements Table
• Differential Table
• Snapshot Table
• Statistics/References
• All

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
AdverseEvent		0..*	AdverseEvent(5.0.0)	An event that may be related to unintended effects on a patient or research participant
AdverseEvent.implicitRules	?! This element is a modifier element. Σ This element is included in summaries.	0..1	uri	A set of rules under which this content was created
AdverseEvent.contained		0..*	Resource	Contained, inline Resources
AdverseEvent.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored Constraints: ext-1
AdverseEvent.identifier	S This element must be supported. Σ This element is included in summaries.	0..*	Identifier	Business identifier for the event
AdverseEvent.status	?! This element is a modifier element. S This element must be supported. Σ This element is included in summaries.	1..1	code	in-progress | completed | entered-in-error | unknown Binding: AdverseEventStatusVS (0.11.1) (required)
AdverseEvent.actuality	?! This element is a modifier element. S This element must be supported. Σ This element is included in summaries.	1..1	code	actual | potential Binding: AdverseEventActualityVS (0.11.1) (required)
AdverseEvent.subject	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Patient(0.11.1) | Group | UZ Core Practitioner(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Subject impacted by event
AdverseEvent.encounter	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Encounter(0.11.1))	The Encounter associated with the start of the AdverseEvent
AdverseEvent.occurrence[x]	S This element must be supported. Σ This element is included in summaries.	0..1		When the event occurred
AdverseEvent.occurrence[x].occurrenceDateTime			dateTime
AdverseEvent.occurrence[x].occurrencePeriod			Period
AdverseEvent.occurrence[x].occurrenceTiming			Timing
AdverseEvent.detected	S This element must be supported. Σ This element is included in summaries.	0..1	dateTime	When the event was detected
AdverseEvent.recordedDate	S This element must be supported. Σ This element is included in summaries.	0..1	dateTime	When the event was recorded
AdverseEvent.resultingEffect	S This element must be supported. Σ This element is included in summaries.	0..*	Reference(UZ Core Condition(0.11.1) | UZ Core Observation(0.11.1))	Effect on the subject due to this event
AdverseEvent.location	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Location(0.11.1))	Location where adverse event occurred
AdverseEvent.seriousness	S This element must be supported. Σ This element is included in summaries.	0..1	CodeableConcept	Seriousness or gravity of the event Binding: AdverseEventSeriousnessVS (0.11.1) (example)
AdverseEvent.outcome	S This element must be supported. Σ This element is included in summaries.	0..*	CodeableConcept	Type of outcome from the adverse event Binding: AdverseEventOutcomeVS (0.11.1) (example)
AdverseEvent.recorder	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who recorded the adverse event
AdverseEvent.participant	S This element must be supported. Σ This element is included in summaries.	0..*	BackboneElement	Who was involved in the adverse event or the potential adverse event and what they did
AdverseEvent.participant.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.participant.function	S This element must be supported. Σ This element is included in summaries.	0..1	CodeableConcept	Type of involvement Binding: AdverseEventParticipantFunction (example)
AdverseEvent.participant.actor	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who was involved in the adverse event or the potential adverse event
AdverseEvent.suspectEntity	S This element must be supported. Σ This element is included in summaries.	0..*	BackboneElement	The suspected agent causing the adverse event
AdverseEvent.suspectEntity.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.suspectEntity.instance[x]	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Immunization(0.11.1) | UZ Core Procedure(0.11.1) | Substance | UZ Core Medication(0.11.1) | MedicationAdministration | MedicationStatement | Device | UZ Core BiologicallyDerivedProduct(0.11.1) | ResearchStudy)	Refers to the specific entity that caused the adverse event
AdverseEvent.note	S This element must be supported. Σ This element is included in summaries.	0..*	Annotation	Comment on adverse event
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
AdverseEvent.status	Base	required	Types of AdverseEvent status	📍0.11.1	This IG
AdverseEvent.actuality	Base	required	Types of AdverseEvent actuality	📍0.11.1	This IG
AdverseEvent.seriousness	Base	example	Types of AdverseEvent seriousness	📍0.11.1	This IG
AdverseEvent.outcome	Base	example	Types of AdverseEvent outcome	📍0.11.1	This IG
AdverseEvent.participant.​function	Base	example	AdverseEvent Participant Function	📍5.0.0	FHIR Std.

Constraints

Id

Grade

Path(s)

Description

Expression

This structure is derived from AdverseEvent

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
AdverseEvent		0..*	AdverseEvent(5.0.0)	An event that may be related to unintended effects on a patient or research participant
AdverseEvent.identifier	S This element must be supported.	0..*	Identifier	Business identifier for the event
AdverseEvent.status	S This element must be supported.	1..1	code	in-progress | completed | entered-in-error | unknown Binding: AdverseEventStatusVS (0.11.1) (required)
AdverseEvent.actuality	S This element must be supported.	1..1	code	actual | potential Binding: AdverseEventActualityVS (0.11.1) (required)
AdverseEvent.subject	S This element must be supported.	1..1	Reference(UZ Core Patient(0.11.1) | Group | UZ Core Practitioner(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Subject impacted by event
AdverseEvent.encounter	S This element must be supported.	0..1	Reference(UZ Core Encounter(0.11.1))	The Encounter associated with the start of the AdverseEvent
AdverseEvent.occurrence[x]	S This element must be supported.	0..1	dateTime, Period, Timing	When the event occurred
AdverseEvent.detected	S This element must be supported.	0..1	dateTime	When the event was detected
AdverseEvent.recordedDate	S This element must be supported.	0..1	dateTime	When the event was recorded
AdverseEvent.resultingEffect	S This element must be supported.	0..*	Reference(UZ Core Condition(0.11.1) | UZ Core Observation(0.11.1))	Effect on the subject due to this event
AdverseEvent.location	S This element must be supported.	0..1	Reference(UZ Core Location(0.11.1))	Location where adverse event occurred
AdverseEvent.seriousness	S This element must be supported.	0..1	CodeableConcept	Seriousness or gravity of the event Binding: AdverseEventSeriousnessVS (0.11.1) (example)
AdverseEvent.outcome	S This element must be supported.	0..*	CodeableConcept	Type of outcome from the adverse event Binding: AdverseEventOutcomeVS (0.11.1) (example)
AdverseEvent.recorder	S This element must be supported.	0..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who recorded the adverse event
AdverseEvent.participant	S This element must be supported.	0..*	BackboneElement	Who was involved in the adverse event or the potential adverse event and what they did
AdverseEvent.participant.function	S This element must be supported.	0..1	CodeableConcept	Type of involvement Binding: AdverseEventParticipantFunction (example)
AdverseEvent.participant.actor	S This element must be supported.	1..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who was involved in the adverse event or the potential adverse event
AdverseEvent.suspectEntity	S This element must be supported.	0..*	BackboneElement	The suspected agent causing the adverse event
AdverseEvent.suspectEntity.instance[x]	S This element must be supported.	1..1	Reference(UZ Core Immunization(0.11.1) | UZ Core Procedure(0.11.1) | Substance | UZ Core Medication(0.11.1) | MedicationAdministration | MedicationStatement | Device | UZ Core BiologicallyDerivedProduct(0.11.1) | ResearchStudy)	Refers to the specific entity that caused the adverse event
AdverseEvent.note	S This element must be supported.	0..*	Annotation	Comment on adverse event
Documentation for this format

Terminology Bindings (Differential)

Path	Status	Usage	ValueSet	Version	Source
AdverseEvent.status	Base	required	Types of AdverseEvent status	📍0.11.1	This IG
AdverseEvent.actuality	Base	required	Types of AdverseEvent actuality	📍0.11.1	This IG
AdverseEvent.seriousness	Base	example	Types of AdverseEvent seriousness	📍0.11.1	This IG
AdverseEvent.outcome	Base	example	Types of AdverseEvent outcome	📍0.11.1	This IG
AdverseEvent.participant.​function	Base	example	AdverseEvent Participant Function	📍5.0.0	FHIR Std.

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
AdverseEvent		0..*	AdverseEvent(5.0.0)	An event that may be related to unintended effects on a patient or research participant
AdverseEvent.id	Σ This element is included in summaries.	0..1	id	Logical id of this artifact
AdverseEvent.meta	Σ This element is included in summaries.	0..1	Meta	Metadata about the resource
AdverseEvent.implicitRules	?! This element is a modifier element. Σ This element is included in summaries.	0..1	uri	A set of rules under which this content was created
AdverseEvent.language		0..1	code	Language of the resource content Binding: AllLanguages (required): IETF language tag for a human language Additional Bindings Purpose CommonLanguages Starter
AdverseEvent.text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
AdverseEvent.contained		0..*	Resource	Contained, inline Resources
AdverseEvent.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored Constraints: ext-1
AdverseEvent.identifier	S This element must be supported. Σ This element is included in summaries.	0..*	Identifier	Business identifier for the event
AdverseEvent.status	?! This element is a modifier element. S This element must be supported. Σ This element is included in summaries.	1..1	code	in-progress | completed | entered-in-error | unknown Binding: AdverseEventStatusVS (0.11.1) (required)
AdverseEvent.actuality	?! This element is a modifier element. S This element must be supported. Σ This element is included in summaries.	1..1	code	actual | potential Binding: AdverseEventActualityVS (0.11.1) (required)
AdverseEvent.category	Σ This element is included in summaries.	0..*	CodeableConcept	wrong-patient | procedure-mishap | medication-mishap | device | unsafe-physical-environment | hospital-aquired-infection | wrong-body-site Binding: AdverseEventCategory (example): Overall categorization of the event, e.g. product-related or situational.
AdverseEvent.code	Σ This element is included in summaries.	0..1	CodeableConcept	Event or incident that occurred or was averted Binding: AdverseEventType (example): Detailed type of event.
AdverseEvent.subject	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Patient(0.11.1) | Group | UZ Core Practitioner(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Subject impacted by event
AdverseEvent.encounter	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Encounter(0.11.1))	The Encounter associated with the start of the AdverseEvent
AdverseEvent.occurrence[x]	S This element must be supported. Σ This element is included in summaries.	0..1		When the event occurred
AdverseEvent.occurrence[x].occurrenceDateTime			dateTime
AdverseEvent.occurrence[x].occurrencePeriod			Period
AdverseEvent.occurrence[x].occurrenceTiming			Timing
AdverseEvent.detected	S This element must be supported. Σ This element is included in summaries.	0..1	dateTime	When the event was detected
AdverseEvent.recordedDate	S This element must be supported. Σ This element is included in summaries.	0..1	dateTime	When the event was recorded
AdverseEvent.resultingEffect	S This element must be supported. Σ This element is included in summaries.	0..*	Reference(UZ Core Condition(0.11.1) | UZ Core Observation(0.11.1))	Effect on the subject due to this event
AdverseEvent.location	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Location(0.11.1))	Location where adverse event occurred
AdverseEvent.seriousness	S This element must be supported. Σ This element is included in summaries.	0..1	CodeableConcept	Seriousness or gravity of the event Binding: AdverseEventSeriousnessVS (0.11.1) (example)
AdverseEvent.outcome	S This element must be supported. Σ This element is included in summaries.	0..*	CodeableConcept	Type of outcome from the adverse event Binding: AdverseEventOutcomeVS (0.11.1) (example)
AdverseEvent.recorder	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who recorded the adverse event
AdverseEvent.participant	S This element must be supported. Σ This element is included in summaries.	0..*	BackboneElement	Who was involved in the adverse event or the potential adverse event and what they did
AdverseEvent.participant.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.participant.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.participant.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.participant.function	S This element must be supported. Σ This element is included in summaries.	0..1	CodeableConcept	Type of involvement Binding: AdverseEventParticipantFunction (example)
AdverseEvent.participant.actor	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who was involved in the adverse event or the potential adverse event
AdverseEvent.study	Σ This element is included in summaries.	0..*	Reference(ResearchStudy)	Research study that the subject is enrolled in
AdverseEvent.expectedInResearchStudy		0..1	boolean	Considered likely or probable or anticipated in the research study
AdverseEvent.suspectEntity	S This element must be supported. Σ This element is included in summaries.	0..*	BackboneElement	The suspected agent causing the adverse event
AdverseEvent.suspectEntity.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.suspectEntity.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.suspectEntity.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.suspectEntity.instance[x]	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Immunization(0.11.1) | UZ Core Procedure(0.11.1) | Substance | UZ Core Medication(0.11.1) | MedicationAdministration | MedicationStatement | Device | UZ Core BiologicallyDerivedProduct(0.11.1) | ResearchStudy)	Refers to the specific entity that caused the adverse event
AdverseEvent.suspectEntity.causality	Σ This element is included in summaries.	0..1	BackboneElement	Information on the possible cause of the event
AdverseEvent.suspectEntity.causality.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.suspectEntity.causality.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.suspectEntity.causality.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.suspectEntity.causality.assessmentMethod	Σ This element is included in summaries.	0..1	CodeableConcept	Method of evaluating the relatedness of the suspected entity to the event Binding: AdverseEventCausalityMethod (example): TODO.
AdverseEvent.suspectEntity.causality.entityRelatedness	Σ This element is included in summaries.	0..1	CodeableConcept	Result of the assessment regarding the relatedness of the suspected entity to the event Binding: AdverseEventCausalityAssessment (example): Codes for the assessment of whether the entity caused the event.
AdverseEvent.suspectEntity.causality.author	Σ This element is included in summaries.	0..1	Reference(Practitioner | PractitionerRole | Patient | RelatedPerson | ResearchSubject)	Author of the information on the possible cause of the event
AdverseEvent.contributingFactor	Σ This element is included in summaries.	0..*	BackboneElement	Contributing factors suspected to have increased the probability or severity of the adverse event
AdverseEvent.contributingFactor.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.contributingFactor.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.contributingFactor.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.contributingFactor.item[x]	Σ This element is included in summaries.	1..1		Item suspected to have increased the probability or severity of the adverse event Binding: AdverseEventContributingFactor (example): Codes describing the contributing factors suspected to have increased the probability or severity of the adverse event.
AdverseEvent.contributingFactor.item[x].itemReference			Reference(Condition | Observation | AllergyIntolerance | FamilyMemberHistory | Immunization | Procedure | Device | DeviceUsage | DocumentReference | MedicationAdministration | MedicationStatement)
AdverseEvent.contributingFactor.item[x].itemCodeableConcept			CodeableConcept
AdverseEvent.preventiveAction	Σ This element is included in summaries.	0..*	BackboneElement	Preventive actions that contributed to avoiding the adverse event
AdverseEvent.preventiveAction.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.preventiveAction.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.preventiveAction.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.preventiveAction.item[x]	Σ This element is included in summaries.	1..1		Action that contributed to avoiding the adverse event Binding: AdverseEventPreventiveAction (example): Codes describing the preventive actions that contributed to avoiding the adverse event.
AdverseEvent.preventiveAction.item[x].itemReference			Reference(Immunization | Procedure | DocumentReference | MedicationAdministration | MedicationRequest)
AdverseEvent.preventiveAction.item[x].itemCodeableConcept			CodeableConcept
AdverseEvent.mitigatingAction	Σ This element is included in summaries.	0..*	BackboneElement	Ameliorating actions taken after the adverse event occured in order to reduce the extent of harm
AdverseEvent.mitigatingAction.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.mitigatingAction.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.mitigatingAction.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.mitigatingAction.item[x]	Σ This element is included in summaries.	1..1		Ameliorating action taken after the adverse event occured in order to reduce the extent of harm Binding: AdverseEventMitigatingAction (example): Codes describing the ameliorating actions taken after the adverse event occured in order to reduce the extent of harm.
AdverseEvent.mitigatingAction.item[x].itemReference			Reference(Procedure | DocumentReference | MedicationAdministration | MedicationRequest)
AdverseEvent.mitigatingAction.item[x].itemCodeableConcept			CodeableConcept
AdverseEvent.supportingInfo	Σ This element is included in summaries.	0..*	BackboneElement	Supporting information relevant to the event
AdverseEvent.supportingInfo.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.supportingInfo.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.supportingInfo.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.supportingInfo.item[x]	Σ This element is included in summaries.	1..1		Subject medical history or document relevant to this adverse event Binding: AdverseEventSupportingInforation (example): Codes describing the supporting information relevant to the event.
AdverseEvent.supportingInfo.item[x].itemReference			Reference(Condition | Observation | AllergyIntolerance | FamilyMemberHistory | Immunization | Procedure | DocumentReference | MedicationAdministration | MedicationStatement | QuestionnaireResponse)
AdverseEvent.supportingInfo.item[x].itemCodeableConcept			CodeableConcept
AdverseEvent.note	S This element must be supported. Σ This element is included in summaries.	0..*	Annotation	Comment on adverse event
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
AdverseEvent.language	Base	required	All Languages	📍5.0.0	FHIR Std.
AdverseEvent.status	Base	required	Types of AdverseEvent status	📍0.11.1	This IG
AdverseEvent.actuality	Base	required	Types of AdverseEvent actuality	📍0.11.1	This IG
AdverseEvent.category	Base	example	Adverse Event Category	📍5.0.0	FHIR Std.
AdverseEvent.code	Base	example	AdverseEvent Type	📍5.0.0	FHIR Std.
AdverseEvent.seriousness	Base	example	Types of AdverseEvent seriousness	📍0.11.1	This IG
AdverseEvent.outcome	Base	example	Types of AdverseEvent outcome	📍0.11.1	This IG
AdverseEvent.participant.​function	Base	example	AdverseEvent Participant Function	📍5.0.0	FHIR Std.
AdverseEvent.suspectEntity.​causality.assessmentMethod	Base	example	Adverse Event Causality Method	📍5.0.0	FHIR Std.
AdverseEvent.suspectEntity.​causality.entityRelatedness	Base	example	Adverse Event Causality Assessment	📍5.0.0	FHIR Std.
AdverseEvent.contributingFactor.​item[x]	Base	example	AdverseEvent Contributing Factor	📍5.0.0	FHIR Std.
AdverseEvent.preventiveAction.​item[x]	Base	example	AdverseEvent Preventive Action	📍5.0.0	FHIR Std.
AdverseEvent.mitigatingAction.​item[x]	Base	example	AdverseEvent Mitigating Action	📍5.0.0	FHIR Std.
AdverseEvent.supportingInfo.​item[x]	Base	example	AdverseEvent Supporting Information	📍5.0.0	FHIR Std.

Constraints

Id

Grade

Path(s)

Description

Expression

Key Elements View

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
AdverseEvent		0..*	AdverseEvent(5.0.0)	An event that may be related to unintended effects on a patient or research participant
AdverseEvent.implicitRules	?! This element is a modifier element. Σ This element is included in summaries.	0..1	uri	A set of rules under which this content was created
AdverseEvent.contained		0..*	Resource	Contained, inline Resources
AdverseEvent.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored Constraints: ext-1
AdverseEvent.identifier	S This element must be supported. Σ This element is included in summaries.	0..*	Identifier	Business identifier for the event
AdverseEvent.status	?! This element is a modifier element. S This element must be supported. Σ This element is included in summaries.	1..1	code	in-progress | completed | entered-in-error | unknown Binding: AdverseEventStatusVS (0.11.1) (required)
AdverseEvent.actuality	?! This element is a modifier element. S This element must be supported. Σ This element is included in summaries.	1..1	code	actual | potential Binding: AdverseEventActualityVS (0.11.1) (required)
AdverseEvent.subject	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Patient(0.11.1) | Group | UZ Core Practitioner(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Subject impacted by event
AdverseEvent.encounter	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Encounter(0.11.1))	The Encounter associated with the start of the AdverseEvent
AdverseEvent.occurrence[x]	S This element must be supported. Σ This element is included in summaries.	0..1		When the event occurred
AdverseEvent.occurrence[x].occurrenceDateTime			dateTime
AdverseEvent.occurrence[x].occurrencePeriod			Period
AdverseEvent.occurrence[x].occurrenceTiming			Timing
AdverseEvent.detected	S This element must be supported. Σ This element is included in summaries.	0..1	dateTime	When the event was detected
AdverseEvent.recordedDate	S This element must be supported. Σ This element is included in summaries.	0..1	dateTime	When the event was recorded
AdverseEvent.resultingEffect	S This element must be supported. Σ This element is included in summaries.	0..*	Reference(UZ Core Condition(0.11.1) | UZ Core Observation(0.11.1))	Effect on the subject due to this event
AdverseEvent.location	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Location(0.11.1))	Location where adverse event occurred
AdverseEvent.seriousness	S This element must be supported. Σ This element is included in summaries.	0..1	CodeableConcept	Seriousness or gravity of the event Binding: AdverseEventSeriousnessVS (0.11.1) (example)
AdverseEvent.outcome	S This element must be supported. Σ This element is included in summaries.	0..*	CodeableConcept	Type of outcome from the adverse event Binding: AdverseEventOutcomeVS (0.11.1) (example)
AdverseEvent.recorder	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who recorded the adverse event
AdverseEvent.participant	S This element must be supported. Σ This element is included in summaries.	0..*	BackboneElement	Who was involved in the adverse event or the potential adverse event and what they did
AdverseEvent.participant.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.participant.function	S This element must be supported. Σ This element is included in summaries.	0..1	CodeableConcept	Type of involvement Binding: AdverseEventParticipantFunction (example)
AdverseEvent.participant.actor	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who was involved in the adverse event or the potential adverse event
AdverseEvent.suspectEntity	S This element must be supported. Σ This element is included in summaries.	0..*	BackboneElement	The suspected agent causing the adverse event
AdverseEvent.suspectEntity.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.suspectEntity.instance[x]	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Immunization(0.11.1) | UZ Core Procedure(0.11.1) | Substance | UZ Core Medication(0.11.1) | MedicationAdministration | MedicationStatement | Device | UZ Core BiologicallyDerivedProduct(0.11.1) | ResearchStudy)	Refers to the specific entity that caused the adverse event
AdverseEvent.note	S This element must be supported. Σ This element is included in summaries.	0..*	Annotation	Comment on adverse event
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
AdverseEvent.status	Base	required	Types of AdverseEvent status	📍0.11.1	This IG
AdverseEvent.actuality	Base	required	Types of AdverseEvent actuality	📍0.11.1	This IG
AdverseEvent.seriousness	Base	example	Types of AdverseEvent seriousness	📍0.11.1	This IG
AdverseEvent.outcome	Base	example	Types of AdverseEvent outcome	📍0.11.1	This IG
AdverseEvent.participant.​function	Base	example	AdverseEvent Participant Function	📍5.0.0	FHIR Std.

Constraints

Id

Grade

Path(s)

Description

Expression

Differential View

This structure is derived from AdverseEvent

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
AdverseEvent		0..*	AdverseEvent(5.0.0)	An event that may be related to unintended effects on a patient or research participant
AdverseEvent.identifier	S This element must be supported.	0..*	Identifier	Business identifier for the event
AdverseEvent.status	S This element must be supported.	1..1	code	in-progress | completed | entered-in-error | unknown Binding: AdverseEventStatusVS (0.11.1) (required)
AdverseEvent.actuality	S This element must be supported.	1..1	code	actual | potential Binding: AdverseEventActualityVS (0.11.1) (required)
AdverseEvent.subject	S This element must be supported.	1..1	Reference(UZ Core Patient(0.11.1) | Group | UZ Core Practitioner(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Subject impacted by event
AdverseEvent.encounter	S This element must be supported.	0..1	Reference(UZ Core Encounter(0.11.1))	The Encounter associated with the start of the AdverseEvent
AdverseEvent.occurrence[x]	S This element must be supported.	0..1	dateTime, Period, Timing	When the event occurred
AdverseEvent.detected	S This element must be supported.	0..1	dateTime	When the event was detected
AdverseEvent.recordedDate	S This element must be supported.	0..1	dateTime	When the event was recorded
AdverseEvent.resultingEffect	S This element must be supported.	0..*	Reference(UZ Core Condition(0.11.1) | UZ Core Observation(0.11.1))	Effect on the subject due to this event
AdverseEvent.location	S This element must be supported.	0..1	Reference(UZ Core Location(0.11.1))	Location where adverse event occurred
AdverseEvent.seriousness	S This element must be supported.	0..1	CodeableConcept	Seriousness or gravity of the event Binding: AdverseEventSeriousnessVS (0.11.1) (example)
AdverseEvent.outcome	S This element must be supported.	0..*	CodeableConcept	Type of outcome from the adverse event Binding: AdverseEventOutcomeVS (0.11.1) (example)
AdverseEvent.recorder	S This element must be supported.	0..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who recorded the adverse event
AdverseEvent.participant	S This element must be supported.	0..*	BackboneElement	Who was involved in the adverse event or the potential adverse event and what they did
AdverseEvent.participant.function	S This element must be supported.	0..1	CodeableConcept	Type of involvement Binding: AdverseEventParticipantFunction (example)
AdverseEvent.participant.actor	S This element must be supported.	1..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who was involved in the adverse event or the potential adverse event
AdverseEvent.suspectEntity	S This element must be supported.	0..*	BackboneElement	The suspected agent causing the adverse event
AdverseEvent.suspectEntity.instance[x]	S This element must be supported.	1..1	Reference(UZ Core Immunization(0.11.1) | UZ Core Procedure(0.11.1) | Substance | UZ Core Medication(0.11.1) | MedicationAdministration | MedicationStatement | Device | UZ Core BiologicallyDerivedProduct(0.11.1) | ResearchStudy)	Refers to the specific entity that caused the adverse event
AdverseEvent.note	S This element must be supported.	0..*	Annotation	Comment on adverse event
Documentation for this format

Terminology Bindings (Differential)

Path	Status	Usage	ValueSet	Version	Source
AdverseEvent.status	Base	required	Types of AdverseEvent status	📍0.11.1	This IG
AdverseEvent.actuality	Base	required	Types of AdverseEvent actuality	📍0.11.1	This IG
AdverseEvent.seriousness	Base	example	Types of AdverseEvent seriousness	📍0.11.1	This IG
AdverseEvent.outcome	Base	example	Types of AdverseEvent outcome	📍0.11.1	This IG
AdverseEvent.participant.​function	Base	example	AdverseEvent Participant Function	📍5.0.0	FHIR Std.

Snapshot ViewView

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
AdverseEvent		0..*	AdverseEvent(5.0.0)	An event that may be related to unintended effects on a patient or research participant
AdverseEvent.id	Σ This element is included in summaries.	0..1	id	Logical id of this artifact
AdverseEvent.meta	Σ This element is included in summaries.	0..1	Meta	Metadata about the resource
AdverseEvent.implicitRules	?! This element is a modifier element. Σ This element is included in summaries.	0..1	uri	A set of rules under which this content was created
AdverseEvent.language		0..1	code	Language of the resource content Binding: AllLanguages (required): IETF language tag for a human language Additional Bindings Purpose CommonLanguages Starter
AdverseEvent.text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
AdverseEvent.contained		0..*	Resource	Contained, inline Resources
AdverseEvent.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored Constraints: ext-1
AdverseEvent.identifier	S This element must be supported. Σ This element is included in summaries.	0..*	Identifier	Business identifier for the event
AdverseEvent.status	?! This element is a modifier element. S This element must be supported. Σ This element is included in summaries.	1..1	code	in-progress | completed | entered-in-error | unknown Binding: AdverseEventStatusVS (0.11.1) (required)
AdverseEvent.actuality	?! This element is a modifier element. S This element must be supported. Σ This element is included in summaries.	1..1	code	actual | potential Binding: AdverseEventActualityVS (0.11.1) (required)
AdverseEvent.category	Σ This element is included in summaries.	0..*	CodeableConcept	wrong-patient | procedure-mishap | medication-mishap | device | unsafe-physical-environment | hospital-aquired-infection | wrong-body-site Binding: AdverseEventCategory (example): Overall categorization of the event, e.g. product-related or situational.
AdverseEvent.code	Σ This element is included in summaries.	0..1	CodeableConcept	Event or incident that occurred or was averted Binding: AdverseEventType (example): Detailed type of event.
AdverseEvent.subject	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Patient(0.11.1) | Group | UZ Core Practitioner(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Subject impacted by event
AdverseEvent.encounter	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Encounter(0.11.1))	The Encounter associated with the start of the AdverseEvent
AdverseEvent.occurrence[x]	S This element must be supported. Σ This element is included in summaries.	0..1		When the event occurred
AdverseEvent.occurrence[x].occurrenceDateTime			dateTime
AdverseEvent.occurrence[x].occurrencePeriod			Period
AdverseEvent.occurrence[x].occurrenceTiming			Timing
AdverseEvent.detected	S This element must be supported. Σ This element is included in summaries.	0..1	dateTime	When the event was detected
AdverseEvent.recordedDate	S This element must be supported. Σ This element is included in summaries.	0..1	dateTime	When the event was recorded
AdverseEvent.resultingEffect	S This element must be supported. Σ This element is included in summaries.	0..*	Reference(UZ Core Condition(0.11.1) | UZ Core Observation(0.11.1))	Effect on the subject due to this event
AdverseEvent.location	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Location(0.11.1))	Location where adverse event occurred
AdverseEvent.seriousness	S This element must be supported. Σ This element is included in summaries.	0..1	CodeableConcept	Seriousness or gravity of the event Binding: AdverseEventSeriousnessVS (0.11.1) (example)
AdverseEvent.outcome	S This element must be supported. Σ This element is included in summaries.	0..*	CodeableConcept	Type of outcome from the adverse event Binding: AdverseEventOutcomeVS (0.11.1) (example)
AdverseEvent.recorder	S This element must be supported. Σ This element is included in summaries.	0..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who recorded the adverse event
AdverseEvent.participant	S This element must be supported. Σ This element is included in summaries.	0..*	BackboneElement	Who was involved in the adverse event or the potential adverse event and what they did
AdverseEvent.participant.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.participant.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.participant.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.participant.function	S This element must be supported. Σ This element is included in summaries.	0..1	CodeableConcept	Type of involvement Binding: AdverseEventParticipantFunction (example)
AdverseEvent.participant.actor	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Patient(0.11.1) | UZ Core Practitioner(0.11.1) | UZ Core PractitionerRole(0.11.1) | UZ Core RelatedPerson(0.11.1) | ResearchSubject)	Who was involved in the adverse event or the potential adverse event
AdverseEvent.study	Σ This element is included in summaries.	0..*	Reference(ResearchStudy)	Research study that the subject is enrolled in
AdverseEvent.expectedInResearchStudy		0..1	boolean	Considered likely or probable or anticipated in the research study
AdverseEvent.suspectEntity	S This element must be supported. Σ This element is included in summaries.	0..*	BackboneElement	The suspected agent causing the adverse event
AdverseEvent.suspectEntity.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.suspectEntity.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.suspectEntity.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.suspectEntity.instance[x]	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(UZ Core Immunization(0.11.1) | UZ Core Procedure(0.11.1) | Substance | UZ Core Medication(0.11.1) | MedicationAdministration | MedicationStatement | Device | UZ Core BiologicallyDerivedProduct(0.11.1) | ResearchStudy)	Refers to the specific entity that caused the adverse event
AdverseEvent.suspectEntity.causality	Σ This element is included in summaries.	0..1	BackboneElement	Information on the possible cause of the event
AdverseEvent.suspectEntity.causality.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.suspectEntity.causality.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.suspectEntity.causality.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.suspectEntity.causality.assessmentMethod	Σ This element is included in summaries.	0..1	CodeableConcept	Method of evaluating the relatedness of the suspected entity to the event Binding: AdverseEventCausalityMethod (example): TODO.
AdverseEvent.suspectEntity.causality.entityRelatedness	Σ This element is included in summaries.	0..1	CodeableConcept	Result of the assessment regarding the relatedness of the suspected entity to the event Binding: AdverseEventCausalityAssessment (example): Codes for the assessment of whether the entity caused the event.
AdverseEvent.suspectEntity.causality.author	Σ This element is included in summaries.	0..1	Reference(Practitioner | PractitionerRole | Patient | RelatedPerson | ResearchSubject)	Author of the information on the possible cause of the event
AdverseEvent.contributingFactor	Σ This element is included in summaries.	0..*	BackboneElement	Contributing factors suspected to have increased the probability or severity of the adverse event
AdverseEvent.contributingFactor.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.contributingFactor.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.contributingFactor.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.contributingFactor.item[x]	Σ This element is included in summaries.	1..1		Item suspected to have increased the probability or severity of the adverse event Binding: AdverseEventContributingFactor (example): Codes describing the contributing factors suspected to have increased the probability or severity of the adverse event.
AdverseEvent.contributingFactor.item[x].itemReference			Reference(Condition | Observation | AllergyIntolerance | FamilyMemberHistory | Immunization | Procedure | Device | DeviceUsage | DocumentReference | MedicationAdministration | MedicationStatement)
AdverseEvent.contributingFactor.item[x].itemCodeableConcept			CodeableConcept
AdverseEvent.preventiveAction	Σ This element is included in summaries.	0..*	BackboneElement	Preventive actions that contributed to avoiding the adverse event
AdverseEvent.preventiveAction.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.preventiveAction.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.preventiveAction.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.preventiveAction.item[x]	Σ This element is included in summaries.	1..1		Action that contributed to avoiding the adverse event Binding: AdverseEventPreventiveAction (example): Codes describing the preventive actions that contributed to avoiding the adverse event.
AdverseEvent.preventiveAction.item[x].itemReference			Reference(Immunization | Procedure | DocumentReference | MedicationAdministration | MedicationRequest)
AdverseEvent.preventiveAction.item[x].itemCodeableConcept			CodeableConcept
AdverseEvent.mitigatingAction	Σ This element is included in summaries.	0..*	BackboneElement	Ameliorating actions taken after the adverse event occured in order to reduce the extent of harm
AdverseEvent.mitigatingAction.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.mitigatingAction.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.mitigatingAction.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.mitigatingAction.item[x]	Σ This element is included in summaries.	1..1		Ameliorating action taken after the adverse event occured in order to reduce the extent of harm Binding: AdverseEventMitigatingAction (example): Codes describing the ameliorating actions taken after the adverse event occured in order to reduce the extent of harm.
AdverseEvent.mitigatingAction.item[x].itemReference			Reference(Procedure | DocumentReference | MedicationAdministration | MedicationRequest)
AdverseEvent.mitigatingAction.item[x].itemCodeableConcept			CodeableConcept
AdverseEvent.supportingInfo	Σ This element is included in summaries.	0..*	BackboneElement	Supporting information relevant to the event
AdverseEvent.supportingInfo.id		0..1	string	Unique id for inter-element referencing
AdverseEvent.supportingInfo.extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
AdverseEvent.supportingInfo.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
AdverseEvent.supportingInfo.item[x]	Σ This element is included in summaries.	1..1		Subject medical history or document relevant to this adverse event Binding: AdverseEventSupportingInforation (example): Codes describing the supporting information relevant to the event.
AdverseEvent.supportingInfo.item[x].itemReference			Reference(Condition | Observation | AllergyIntolerance | FamilyMemberHistory | Immunization | Procedure | DocumentReference | MedicationAdministration | MedicationStatement | QuestionnaireResponse)
AdverseEvent.supportingInfo.item[x].itemCodeableConcept			CodeableConcept
AdverseEvent.note	S This element must be supported. Σ This element is included in summaries.	0..*	Annotation	Comment on adverse event
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
AdverseEvent.language	Base	required	All Languages	📍5.0.0	FHIR Std.
AdverseEvent.status	Base	required	Types of AdverseEvent status	📍0.11.1	This IG
AdverseEvent.actuality	Base	required	Types of AdverseEvent actuality	📍0.11.1	This IG
AdverseEvent.category	Base	example	Adverse Event Category	📍5.0.0	FHIR Std.
AdverseEvent.code	Base	example	AdverseEvent Type	📍5.0.0	FHIR Std.
AdverseEvent.seriousness	Base	example	Types of AdverseEvent seriousness	📍0.11.1	This IG
AdverseEvent.outcome	Base	example	Types of AdverseEvent outcome	📍0.11.1	This IG
AdverseEvent.participant.​function	Base	example	AdverseEvent Participant Function	📍5.0.0	FHIR Std.
AdverseEvent.suspectEntity.​causality.assessmentMethod	Base	example	Adverse Event Causality Method	📍5.0.0	FHIR Std.
AdverseEvent.suspectEntity.​causality.entityRelatedness	Base	example	Adverse Event Causality Assessment	📍5.0.0	FHIR Std.
AdverseEvent.contributingFactor.​item[x]	Base	example	AdverseEvent Contributing Factor	📍5.0.0	FHIR Std.
AdverseEvent.preventiveAction.​item[x]	Base	example	AdverseEvent Preventive Action	📍5.0.0	FHIR Std.
AdverseEvent.mitigatingAction.​item[x]	Base	example	AdverseEvent Mitigating Action	📍5.0.0	FHIR Std.
AdverseEvent.supportingInfo.​item[x]	Base	example	AdverseEvent Supporting Information	📍5.0.0	FHIR Std.

Constraints

Id

Grade

Path(s)

Description

Expression

This structure is derived from AdverseEvent

Summary

Must-Support: 19 elements

Structures

This structure refers to these other structures:

• UZ Core Patient (https://dhp.uz/fhir/core/StructureDefinition/uz-core-patient|0.11.1)
• Group (http://hl7.org/fhir/StructureDefinition/Group|5.0.0)
• UZ Core Practitioner (https://dhp.uz/fhir/core/StructureDefinition/uz-core-practitioner|0.11.1)
• UZ Core RelatedPerson (https://dhp.uz/fhir/core/StructureDefinition/uz-core-relatedperson|0.11.1)
• ResearchSubject (http://hl7.org/fhir/StructureDefinition/ResearchSubject|5.0.0)
• UZ Core Encounter (https://dhp.uz/fhir/core/StructureDefinition/uz-core-encounter|0.11.1)
• UZ Core Condition (https://dhp.uz/fhir/core/StructureDefinition/uz-core-condition|0.11.1)
• UZ Core Observation (https://dhp.uz/fhir/core/StructureDefinition/uz-core-observation|0.11.1)
• UZ Core Location (https://dhp.uz/fhir/core/StructureDefinition/uz-core-location|0.11.1)
• UZ Core PractitionerRole (https://dhp.uz/fhir/core/StructureDefinition/uz-core-practitioner-role|0.11.1)
• UZ Core Immunization (https://dhp.uz/fhir/core/StructureDefinition/uz-core-immunization|0.11.1)
• UZ Core Procedure (https://dhp.uz/fhir/core/StructureDefinition/uz-core-procedure|0.11.1)
• Substance (http://hl7.org/fhir/StructureDefinition/Substance|5.0.0)
• UZ Core Medication (https://dhp.uz/fhir/core/StructureDefinition/uz-core-medication|0.11.1)
• MedicationAdministration (http://hl7.org/fhir/StructureDefinition/MedicationAdministration|5.0.0)
• MedicationStatement (http://hl7.org/fhir/StructureDefinition/MedicationStatement|5.0.0)
• Device (http://hl7.org/fhir/StructureDefinition/Device|5.0.0)
• UZ Core BiologicallyDerivedProduct (https://dhp.uz/fhir/core/StructureDefinition/uz-core-biologically-derived-product|0.11.1)
• ResearchStudy (http://hl7.org/fhir/StructureDefinition/ResearchStudy|5.0.0)

Quick Start

Common API interactions for this profile. Requests require a JWT access token - see Security and authentication. [base] is the FHIR server base URL; | separates a token system from its value and must be URL-encoded as %7C. These interactions use standard FHIR R5 search parameters; see the CapabilityStatement as it is finalized for this resource.

Read an adverse event by server id

GET [base]/AdverseEvent/[id]

Useful searches

# all adverse events for a patient
GET [base]/AdverseEvent?subject=Patient/[id]

# serious events only, most recent first
GET [base]/AdverseEvent?subject=Patient/[id]&seriousness=http://terminology.hl7.org/CodeSystem/adverse-event-seriousness%7Cserious&_sort=-date

# by date, status, or event code
GET [base]/AdverseEvent?subject=Patient/[id]&date=ge2026-01-01
GET [base]/AdverseEvent?status=completed
GET [base]/AdverseEvent?code=http://snomed.info/sct%7C39579001

Record a new adverse event

POST [base]/AdverseEvent
{
  "resourceType": "AdverseEvent",
  "meta": { "profile": [ "https://dhp.uz/fhir/core/StructureDefinition/uz-core-adverse-event" ] },
  ...
}

Update an adverse event (e.g. add an outcome or the resulting condition once known)

PUT [base]/AdverseEvent/[id]
If-Match: W/"3"   # the ETag from your last read; 412 if it changed since
{
  "resourceType": "AdverseEvent",
  "id": "[id]",
  "meta": { "profile": [ "https://dhp.uz/fhir/core/StructureDefinition/uz-core-adverse-event" ] },
  ...
}

Related

• Immunization workflow
• How to read this guide · Must Support · General guidance