HL7 Europe Common Cancer Model
1.0.0-ballot - ballot
150
HL7 Europe Common Cancer Model
1.0.0-ballot - ballot
150
HL7 Europe Common Cancer Model, published by HL7 Europe. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/cancer-common/ and changes regularly. See the Directory of published versions
| Active as of 2026-10-20 |
XML representation of the ClinicalCancerProgression logical model.
<StructureDefinition xmlns="http://hl7.org/fhir">
<id value="ClinicalCancerProgression"/>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: StructureDefinition ClinicalCancerProgression</b></p><table border="0" cellpadding="0" cellspacing="0" class="xhtTableBorder0"><tr class="xhtRowBorder1"><th scope="col" style="" class="hierarchy xhtCellBorder0"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="The logical name of the element">Name</a></th><th scope="col" style="" class="hierarchy xhtCellBorder0"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Information about the use of the element">Flags</a></th><th scope="col" style="" class="hierarchy xhtCellBorder0"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Minimum and Maximum # of times the element can appear in the instance">Card.</a></th><th scope="col" style="; width: 100px" class="hierarchy xhtCellBorder0"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Reference to the type of the element">Type</a></th><th scope="col" style="" class="hierarchy xhtCellBorder0"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Additional information about the element">Description & Constraints</a><span style="float: right"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/></a></span></th></tr><tr class="xhtRowBorder0 xhtRowEven"><td style="background-image: url(tbl_bck1.png)" class="hierarchy xhtCellBorder0 xhtCellNoWrap"><img src="tbl_spacer.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="icon_element.gif" alt="" style="background-color: white; background-color: inherit" title="Element" class="hierarchy"/> <a href="StructureDefinition-ClinicalCancerProgression-definitions.html#ClinicalCancerProgression" title="Logical model representing the longitudinal evolution of the cancer disease, documenting disease status and extent at a specific point in time. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet ClinicalCancerProgression).">ClinicalCancerProgression</a><a name="ClinicalCancerProgression"> </a></td><td style="" class="hierarchy xhtCellBorder0"><a href="http://hl7.org/fhir/R4/conformance-rules.html#constraints" title="This element has or is affected by constraints ( ccp-1, ccp-2 )" class="xhtConstraintStyle">C</a></td><td style="" class="hierarchy xhtCellBorder0"><span class="xhtPieceDeEmphasized">0</span><span class="xhtPieceDeEmphasized">..</span><span class="xhtPieceDeEmphasized">*</span></td><td style="" class="hierarchy xhtCellBorder0"><a href="http://build.fhir.org/types.html#Base">Base</a></td><td style="" class="hierarchy xhtCellBorder0">ClinicalCancerProgression<br/><span class="xhtPieceBold">Instances of this type can be the target of a Reference</span><br class="constraint"/><span class="constraint">Constraints: </span><span title="LocoRegionalSites must be present if ExtentType is Loco-regional" class="xhtPieceBold constraint">ccp-1</span><span class="constraint">, </span><span title="MetastaticSites must be present if ExtentType is Metastatic" class="xhtPieceBold constraint">ccp-2</span></td></tr>
<tr class="xhtRowBorder0 xhtRowOdd"><td style="background-image: url(tbl_bck10.png)" class="hierarchy xhtCellBorder0 xhtCellNoWrap"><img src="tbl_spacer.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="icon_reference.png" alt="" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource" class="hierarchy"/> <span style="position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0" class="sr-only">ClinicalCancerProgression.</span><a href="StructureDefinition-ClinicalCancerProgression-definitions.html#ClinicalCancerProgression.cancerConditionAtDiagnosisReference" title="Reference to the original cancer condition at diagnosis to which this progression refers.">cancerConditionAtDiagnosisReference</a><a name="ClinicalCancerProgression.cancerConditionAtDiagnosisReference"> </a></td><td style="" class="hierarchy xhtCellBorder0"/><td style="" class="hierarchy xhtCellBorder0">1..1</td><td style="" class="hierarchy xhtCellBorder0"><a href="http://hl7.org/fhir/R4/references.html">Reference</a>(<a href="StructureDefinition-CancerConditionAtDiagnosis.html">CancerConditionAtDiagnosis</a>)</td><td style="" class="hierarchy xhtCellBorder0">CancerConditionReference</td></tr>
<tr class="xhtRowBorder0 xhtRowEven"><td style="background-image: url(tbl_bck10.png)" class="hierarchy xhtCellBorder0 xhtCellNoWrap"><img src="tbl_spacer.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="" style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <span style="position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0" class="sr-only">ClinicalCancerProgression.</span><a href="StructureDefinition-ClinicalCancerProgression-definitions.html#ClinicalCancerProgression.diseaseStatus" title="Disease status at this time point (e.g. progression, stable disease, remission, recurrence).">diseaseStatus</a><a name="ClinicalCancerProgression.diseaseStatus"> </a></td><td style="" class="hierarchy xhtCellBorder0"/><td style="" class="hierarchy xhtCellBorder0">1..1</td><td style="" class="hierarchy xhtCellBorder0"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="" class="hierarchy xhtCellBorder0">DiseaseStatus</td></tr>
<tr class="xhtRowBorder0 xhtRowOdd"><td style="background-image: url(tbl_bck10.png)" class="hierarchy xhtCellBorder0 xhtCellNoWrap"><img src="tbl_spacer.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="" style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <span style="position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0" class="sr-only">ClinicalCancerProgression.</span><a href="StructureDefinition-ClinicalCancerProgression-definitions.html#ClinicalCancerProgression.tumourGradeSystem" title="Classification system used to define tumour grade, describing how abnormal tumour cells and tissue appear under microscopic examination (e.g. Gleason for prostate cancer, FNCLCC for soft tissue sarcomas). The grading system provides an indication of the biological aggressiveness of the tumour.">tumourGradeSystem</a><a name="ClinicalCancerProgression.tumourGradeSystem"> </a></td><td style="" class="hierarchy xhtCellBorder0"/><td style="" class="hierarchy xhtCellBorder0">0..1</td><td style="" class="hierarchy xhtCellBorder0"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="" class="hierarchy xhtCellBorder0">TumourGradeSystem</td></tr>
<tr class="xhtRowBorder0 xhtRowEven"><td style="background-image: url(tbl_bck10.png)" class="hierarchy xhtCellBorder0 xhtCellNoWrap"><img src="tbl_spacer.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="" style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <span style="position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0" class="sr-only">ClinicalCancerProgression.</span><a href="StructureDefinition-ClinicalCancerProgression-definitions.html#ClinicalCancerProgression.tumourGradeValue" title="Grade value assigned according to the selected TumourGradeSystem. The grade reflects the degree of cellular differentiation and biological aggressiveness of the tumour and may evolve over time.">tumourGradeValue</a><a name="ClinicalCancerProgression.tumourGradeValue"> </a></td><td style="" class="hierarchy xhtCellBorder0"/><td style="" class="hierarchy xhtCellBorder0">0..1</td><td style="" class="hierarchy xhtCellBorder0"><a href="http://hl7.org/fhir/R4/datatypes.html#string">string</a></td><td style="" class="hierarchy xhtCellBorder0">TumourGradeValue</td></tr>
<tr class="xhtRowBorder0 xhtRowOdd"><td style="background-image: url(tbl_bck10.png)" class="hierarchy xhtCellBorder0 xhtCellNoWrap"><img src="tbl_spacer.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="" style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <span style="position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0" class="sr-only">ClinicalCancerProgression.</span><a href="StructureDefinition-ClinicalCancerProgression-definitions.html#ClinicalCancerProgression.assertedDate" title="Date when this progression/status was asserted/recorded.">assertedDate</a><a name="ClinicalCancerProgression.assertedDate"> </a></td><td style="" class="hierarchy xhtCellBorder0"/><td style="" class="hierarchy xhtCellBorder0">1..1</td><td style="" class="hierarchy xhtCellBorder0"><a href="http://hl7.org/fhir/R4/datatypes.html#dateTime">dateTime</a></td><td style="" class="hierarchy xhtCellBorder0">AssertedDate</td></tr>
<tr class="xhtRowBorder0 xhtRowEven"><td style="background-image: url(tbl_bck10.png)" class="hierarchy xhtCellBorder0 xhtCellNoWrap"><img src="tbl_spacer.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="" style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <span style="position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0" class="sr-only">ClinicalCancerProgression.</span><a href="StructureDefinition-ClinicalCancerProgression-definitions.html#ClinicalCancerProgression.extentType" title="Extent of disease at this time point (Local, Loco-regional, Metastatic).">extentType</a><a name="ClinicalCancerProgression.extentType"> </a></td><td style="" class="hierarchy xhtCellBorder0"/><td style="" class="hierarchy xhtCellBorder0">0..1</td><td style="" class="hierarchy xhtCellBorder0"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="" class="hierarchy xhtCellBorder0">ExtentType</td></tr>
<tr class="xhtRowBorder0 xhtRowOdd"><td style="background-image: url(tbl_bck10.png)" class="hierarchy xhtCellBorder0 xhtCellNoWrap"><img src="tbl_spacer.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="" style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <span style="position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0" class="sr-only">ClinicalCancerProgression.</span><a href="StructureDefinition-ClinicalCancerProgression-definitions.html#ClinicalCancerProgression.locoRegionalSites" title="Sites involved when ExtentType is Loco-regional.">locoRegionalSites</a><a name="ClinicalCancerProgression.locoRegionalSites"> </a></td><td style="" class="hierarchy xhtCellBorder0"/><td style="" class="hierarchy xhtCellBorder0">0..*</td><td style="" class="hierarchy xhtCellBorder0"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="" class="hierarchy xhtCellBorder0">LocoRegionalSites<br/></td></tr>
<tr class="xhtRowBorder0 xhtRowEven"><td style="background-image: url(tbl_bck00.png)" class="hierarchy xhtCellBorder0 xhtCellNoWrap"><img src="tbl_spacer.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="" style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="" style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <span style="position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0" class="sr-only">ClinicalCancerProgression.</span><a href="StructureDefinition-ClinicalCancerProgression-definitions.html#ClinicalCancerProgression.metastaticSites" title="Sites involved when ExtentType is Metastatic.">metastaticSites</a><a name="ClinicalCancerProgression.metastaticSites"> </a></td><td style="" class="hierarchy xhtCellBorder0"/><td style="" class="hierarchy xhtCellBorder0">0..*</td><td style="" class="hierarchy xhtCellBorder0"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="" class="hierarchy xhtCellBorder0">MetastaticSites<br/></td></tr>
<tr><td colspan="5" class="hierarchy"><br/><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/> Documentation for this format</a></td></tr></table></div>
</text>
<extension
url="http://hl7.org/fhir/StructureDefinition/structuredefinition-type-characteristics">
<valueCode value="can-be-target"/>
</extension>
<url
value="http://hl7.eu/fhir/cancer-common/StructureDefinition/ClinicalCancerProgression"/>
<version value="1.0.0-ballot"/>
<name value="ClinicalCancerProgression"/>
<title value="ClinicalCancerProgression"/>
<status value="active"/>
<date value="2026-10-20T16:00:15+00:00"/>
<publisher value="HL7 Europe"/>
<contact>
<name value="HL7 Europe"/>
<telecom>
<system value="url"/>
<value value="http://hl7.eu"/>
</telecom>
</contact>
<description
value="Logical model representing the longitudinal evolution of the cancer disease, documenting disease status and extent at a specific point in time. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet ClinicalCancerProgression)."/>
<jurisdiction>
<coding>
<system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
<code value="150"/>
<display value="Europe"/>
</coding>
</jurisdiction>
<copyright
value="HL7 Europe Copyright. Licensed under Common Creative License (CC0 1.0). Details at [Copyright](copyright.html)."/>
<fhirVersion value="4.0.1"/>
<kind value="logical"/>
<abstract value="false"/>
<type
value="http://hl7.eu/fhir/cancer-common/StructureDefinition/ClinicalCancerProgression"/>
<baseDefinition value="http://hl7.org/fhir/StructureDefinition/Base"/>
<derivation value="specialization"/>
<snapshot>
<extension
url="http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version">
<valueString value="4.0.1"/>
</extension>
<element id="ClinicalCancerProgression">
<path value="ClinicalCancerProgression"/>
<short value="ClinicalCancerProgression"/>
<definition
value="Logical model representing the longitudinal evolution of the cancer disease, documenting disease status and extent at a specific point in time. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet ClinicalCancerProgression)."/>
<min value="0"/>
<max value="*"/>
<base>
<path value="Base"/>
<min value="0"/>
<max value="*"/>
</base>
<constraint>
<key value="ccp-1"/>
<severity value="error"/>
<human
value="LocoRegionalSites must be present if ExtentType is Loco-regional"/>
<expression
value="extentType.coding.where(code = 'Loco-regional').exists() implies locoRegionalSites.exists()"/>
<source
value="http://hl7.eu/fhir/cancer-common/StructureDefinition/ClinicalCancerProgression"/>
</constraint>
<constraint>
<key value="ccp-2"/>
<severity value="error"/>
<human
value="MetastaticSites must be present if ExtentType is Metastatic"/>
<expression
value="extentType.coding.where(code = 'Metastatic').exists() implies metastaticSites.exists()"/>
<source
value="http://hl7.eu/fhir/cancer-common/StructureDefinition/ClinicalCancerProgression"/>
</constraint>
<isModifier value="false"/>
</element>
<element
id="ClinicalCancerProgression.cancerConditionAtDiagnosisReference">
<path
value="ClinicalCancerProgression.cancerConditionAtDiagnosisReference"/>
<short value="CancerConditionReference"/>
<definition
value="Reference to the original cancer condition at diagnosis to which this progression refers."/>
<min value="1"/>
<max value="1"/>
<base>
<path
value="ClinicalCancerProgression.cancerConditionAtDiagnosisReference"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerConditionAtDiagnosis"/>
</type>
</element>
<element id="ClinicalCancerProgression.diseaseStatus">
<path value="ClinicalCancerProgression.diseaseStatus"/>
<short value="DiseaseStatus"/>
<definition
value="Disease status at this time point (e.g. progression, stable disease, remission, recurrence)."/>
<comment
value="Choice: Progression | Stable Disease | Partial Remission | Complete Remission | Recurrence"/>
<min value="1"/>
<max value="1"/>
<base>
<path value="ClinicalCancerProgression.diseaseStatus"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="ClinicalCancerProgression.tumourGradeSystem">
<path value="ClinicalCancerProgression.tumourGradeSystem"/>
<short value="TumourGradeSystem"/>
<definition
value="Classification system used to define tumour grade, describing how abnormal tumour cells and tissue appear under microscopic examination (e.g. Gleason for prostate cancer, FNCLCC for soft tissue sarcomas). The grading system provides an indication of the biological aggressiveness of the tumour."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="ClinicalCancerProgression.tumourGradeSystem"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="ClinicalCancerProgression.tumourGradeValue">
<path value="ClinicalCancerProgression.tumourGradeValue"/>
<short value="TumourGradeValue"/>
<definition
value="Grade value assigned according to the selected TumourGradeSystem. The grade reflects the degree of cellular differentiation and biological aggressiveness of the tumour and may evolve over time."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="ClinicalCancerProgression.tumourGradeValue"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="string"/>
</type>
</element>
<element id="ClinicalCancerProgression.assertedDate">
<path value="ClinicalCancerProgression.assertedDate"/>
<short value="AssertedDate"/>
<definition
value="Date when this progression/status was asserted/recorded."/>
<min value="1"/>
<max value="1"/>
<base>
<path value="ClinicalCancerProgression.assertedDate"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="dateTime"/>
</type>
</element>
<element id="ClinicalCancerProgression.extentType">
<path value="ClinicalCancerProgression.extentType"/>
<short value="ExtentType"/>
<definition
value="Extent of disease at this time point (Local, Loco-regional, Metastatic)."/>
<comment value="Choice: Local | Loco-regional | Metastatic"/>
<min value="0"/>
<max value="1"/>
<base>
<path value="ClinicalCancerProgression.extentType"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="ClinicalCancerProgression.locoRegionalSites">
<path value="ClinicalCancerProgression.locoRegionalSites"/>
<short value="LocoRegionalSites"/>
<definition value="Sites involved when ExtentType is Loco-regional."/>
<comment value="It must be present if the ExtentType is Loco-regional"/>
<min value="0"/>
<max value="*"/>
<base>
<path value="ClinicalCancerProgression.locoRegionalSites"/>
<min value="0"/>
<max value="*"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="ClinicalCancerProgression.metastaticSites">
<path value="ClinicalCancerProgression.metastaticSites"/>
<short value="MetastaticSites"/>
<definition value="Sites involved when ExtentType is Metastatic."/>
<comment value="It must be present if the ExtentType is Metastatic"/>
<min value="0"/>
<max value="*"/>
<base>
<path value="ClinicalCancerProgression.metastaticSites"/>
<min value="0"/>
<max value="*"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
</snapshot>
<differential>
<element id="ClinicalCancerProgression">
<path value="ClinicalCancerProgression"/>
<short value="ClinicalCancerProgression"/>
<definition
value="Logical model representing the longitudinal evolution of the cancer disease, documenting disease status and extent at a specific point in time. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet ClinicalCancerProgression)."/>
<constraint>
<key value="ccp-1"/>
<severity value="error"/>
<human
value="LocoRegionalSites must be present if ExtentType is Loco-regional"/>
<expression
value="extentType.coding.where(code = 'Loco-regional').exists() implies locoRegionalSites.exists()"/>
<source
value="http://hl7.eu/fhir/cancer-common/StructureDefinition/ClinicalCancerProgression"/>
</constraint>
<constraint>
<key value="ccp-2"/>
<severity value="error"/>
<human
value="MetastaticSites must be present if ExtentType is Metastatic"/>
<expression
value="extentType.coding.where(code = 'Metastatic').exists() implies metastaticSites.exists()"/>
<source
value="http://hl7.eu/fhir/cancer-common/StructureDefinition/ClinicalCancerProgression"/>
</constraint>
</element>
<element
id="ClinicalCancerProgression.cancerConditionAtDiagnosisReference">
<path
value="ClinicalCancerProgression.cancerConditionAtDiagnosisReference"/>
<short value="CancerConditionReference"/>
<definition
value="Reference to the original cancer condition at diagnosis to which this progression refers."/>
<min value="1"/>
<max value="1"/>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerConditionAtDiagnosis"/>
</type>
</element>
<element id="ClinicalCancerProgression.diseaseStatus">
<path value="ClinicalCancerProgression.diseaseStatus"/>
<short value="DiseaseStatus"/>
<definition
value="Disease status at this time point (e.g. progression, stable disease, remission, recurrence)."/>
<comment
value="Choice: Progression | Stable Disease | Partial Remission | Complete Remission | Recurrence"/>
<min value="1"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="ClinicalCancerProgression.tumourGradeSystem">
<path value="ClinicalCancerProgression.tumourGradeSystem"/>
<short value="TumourGradeSystem"/>
<definition
value="Classification system used to define tumour grade, describing how abnormal tumour cells and tissue appear under microscopic examination (e.g. Gleason for prostate cancer, FNCLCC for soft tissue sarcomas). The grading system provides an indication of the biological aggressiveness of the tumour."/>
<min value="0"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="ClinicalCancerProgression.tumourGradeValue">
<path value="ClinicalCancerProgression.tumourGradeValue"/>
<short value="TumourGradeValue"/>
<definition
value="Grade value assigned according to the selected TumourGradeSystem. The grade reflects the degree of cellular differentiation and biological aggressiveness of the tumour and may evolve over time."/>
<min value="0"/>
<max value="1"/>
<type>
<code value="string"/>
</type>
</element>
<element id="ClinicalCancerProgression.assertedDate">
<path value="ClinicalCancerProgression.assertedDate"/>
<short value="AssertedDate"/>
<definition
value="Date when this progression/status was asserted/recorded."/>
<min value="1"/>
<max value="1"/>
<type>
<code value="dateTime"/>
</type>
</element>
<element id="ClinicalCancerProgression.extentType">
<path value="ClinicalCancerProgression.extentType"/>
<short value="ExtentType"/>
<definition
value="Extent of disease at this time point (Local, Loco-regional, Metastatic)."/>
<comment value="Choice: Local | Loco-regional | Metastatic"/>
<min value="0"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="ClinicalCancerProgression.locoRegionalSites">
<path value="ClinicalCancerProgression.locoRegionalSites"/>
<short value="LocoRegionalSites"/>
<definition value="Sites involved when ExtentType is Loco-regional."/>
<comment value="It must be present if the ExtentType is Loco-regional"/>
<min value="0"/>
<max value="*"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="ClinicalCancerProgression.metastaticSites">
<path value="ClinicalCancerProgression.metastaticSites"/>
<short value="MetastaticSites"/>
<definition value="Sites involved when ExtentType is Metastatic."/>
<comment value="It must be present if the ExtentType is Metastatic"/>
<min value="0"/>
<max value="*"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
</differential>
</StructureDefinition>
IG © 2023+ HL7 Europe. Package hl7.fhir.eu.cancer-common#1.0.0-ballot based on FHIR 4.0.1. Generated 2026-10-20
