minimal Common Oncology Data Elements (mCODE) Implementation Guide
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minimal Common Oncology Data Elements (mCODE) Implementation Guide, published by HL7 International / Clinical Interoperability Council. This guide is not an authorized publication; it is the continuous build for version 4.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of and changes regularly. See the Directory of published versions

ValueSet: Histology Morphology Behavior Value Set

Official URL: Version: 4.0.0-ballot
Active as of 2024-04-09 Maturity Level: 4 Computable Name: HistologyMorphologyBehaviorVS
Other Identifiers: OID:2.16.840.1.113883.4.642.

Copyright/Legal: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement

Codes representing the structure, arrangement, and behavioral characteristics of malignant neoplasms, and cancer cells. Inclusion criteria: in situ neoplasms and malignant neoplasms. Exclusion criteria: benign neoplasms and neoplasms of unspecified behavior. Note: ICD-O-3 morphology codes are referenced in the logical definition but not expanded in the value set for intellectual property reasons. For primary cancers, the ICD-O-3 behavior suffix should be /1, /2, or /3. For secondary cancers, the ICD-O-3 behavior suffix should be /6.


Changes since version true:

Logical Definition (CLD)

This value set includes codes based on the following rules:

This value set excludes codes based on the following rules:

  • Exclude codes from where concept is-a 450893003 (Papillary neoplasm, pancreatobiliary-type, with high grade intraepithelial neoplasia (morphologic abnormality))
  • Exclude codes from where concept is-a 128640002 (Prostatic intraepithelial neoplasia, grade III)
  • Exclude codes from where concept is-a 450890000 (Glandular intraepithelial neoplasia, low grade)
  • Exclude codes from where concept is-a 703548001 (Atypical hyperplasia of the endometrium)



Expansion based on code system fragment version 2000

Expansion based on:

  • SNOMED CT International edition 01-Feb 2024
  • codesystem version 2000

This value set expansion contains 6 concepts.

  8500/3 duct carcinoma, NOS
  367651003 Neoplasm (Morphology)inactive
  399919001 in situ - category (morphologic abnormality)inactive
  399983006 situ adenomatous neoplasm - category (morphologic abnormality)inactive
  399878004 neoplasm with pilar differentiation (morphologic abnormality)
  253035009 situ melanocytic morphology

Explanation of the columns that may appear on this page:

Level A few code lists that FHIR defines are hierarchical - each code is assigned a level. In this scheme, some codes are under other codes, and imply that the code they are under also applies
System The source of the definition of the code (when the value set draws in codes defined elsewhere)
Code The code (used as the code in the resource instance)
Display The display (used in the display element of a Coding). If there is no display, implementers should not simply display the code, but map the concept into their application
Definition An explanation of the meaning of the concept
Comments Additional notes about how to use the code