HL7 FHIR Implementation Guide: Profiles for Transfusion and Vaccination Adverse Event Detection and Reporting
1.0.1 - STU 1 Technical Correction United States of America flag

HL7 FHIR Implementation Guide: Profiles for Transfusion and Vaccination Adverse Event Detection and Reporting, published by Biomedical Research & Regulation WG. This is not an authorized publication; it is the continuous build for version 1.0.1). This version is based on the current content of https://github.com/HL7/fhir-icsr-ae-reporting/ and changes regularly. See the Directory of published versions

: Transfusion Bundle for Connectathon Sample - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <https://loinc.org/rdf/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Bundle ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "ConnectathonTransfusionBundle"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bundle"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bundle>     ] )
  ] ; # 
  fhir:type [ fhir:v "message"] ; # 
  fhir:entry ( [
fhir:fullUrl [ fhir:v "MessageHeader/beafb541-3eab-eb9e-1bf1-5fa477d56e77"^^xsd:anyURI ] ;
    ( fhir:resource <MessageHeader/beafb541-3eab-eb9e-1bf1-5fa477d56e77> )
  ] [
fhir:fullUrl [ fhir:v "Composition/TransfusionExample"^^xsd:anyURI ] ;
    ( fhir:resource <Composition/TransfusionExample> )
  ] [
fhir:fullUrl [ fhir:v "Organization/FDA"^^xsd:anyURI ] ;
    ( fhir:resource <Organization/FDA> )
  ] [
fhir:fullUrl [ fhir:v "Organization/BESTPrototype"^^xsd:anyURI ] ;
    ( fhir:resource <Organization/BESTPrototype> )
  ] [
fhir:fullUrl [ fhir:v "PractitionerRole/BESTAuthorRole"^^xsd:anyURI ] ;
    ( fhir:resource <PractitionerRole/BESTAuthorRole> )
  ] [
fhir:fullUrl [ fhir:v "Practitioner/BESTAuthor"^^xsd:anyURI ] ;
    ( fhir:resource <Practitioner/BESTAuthor> )
  ] [
fhir:fullUrl [ fhir:v "Patient/BESTPatient"^^xsd:anyURI ] ;
    ( fhir:resource <Patient/BESTPatient> )
  ] [
fhir:fullUrl [ fhir:v "Observation/BESTPatientAgeGroup"^^xsd:anyURI ] ;
    ( fhir:resource <Observation/BESTPatientAgeGroup> )
  ] [
fhir:fullUrl [ fhir:v "AdverseEvent/TransfusionExampleEvent"^^xsd:anyURI ] ;
    ( fhir:resource <AdverseEvent/TransfusionExampleEvent> )
  ] [
fhir:fullUrl [ fhir:v "Procedure/TransfusionExampleTransfusion"^^xsd:anyURI ] ;
    ( fhir:resource <Procedure/TransfusionExampleTransfusion> )
  ] [
fhir:fullUrl [ fhir:v "BiologicallyDerivedProduct/TransfusionBloodProduct"^^xsd:anyURI ] ;
    ( fhir:resource <BiologicallyDerivedProduct/TransfusionBloodProduct> )
  ] [
fhir:fullUrl [ fhir:v "MedicationAdministration/TransfusionEpinephrine"^^xsd:anyURI ] ;
    ( fhir:resource <MedicationAdministration/TransfusionEpinephrine> )
  ] [
fhir:fullUrl [ fhir:v "MedicationAdministration/TransfusionDiphenhydramine"^^xsd:anyURI ] ;
    ( fhir:resource <MedicationAdministration/TransfusionDiphenhydramine> )
  ] ) . # 

<MessageHeader/beafb541-3eab-eb9e-1bf1-5fa477d56e77> a fhir:MessageHeader ;
  fhir:id [ fhir:v "beafb541-3eab-eb9e-1bf1-5fa477d56e77"] ; # 
  fhir:meta [
fhir:lastUpdated [ fhir:v "2021-01-05T14:14:39+06:00"^^xsd:dateTime ] ;
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageheader"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageheader>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: MessageHeader</b><a name=\"beafb541-3eab-eb9e-1bf1-5fa477d56e77\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MessageHeader &quot;beafb541-3eab-eb9e-1bf1-5fa477d56e77&quot; Updated &quot;2021-01-05 14:14:39+0600&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-messageheader.html\">ICSR MessageHeader</a></p></div><p><b>Message Processing Category</b>: notification</p><p><b>event</b>: Patient Adverse Event (Details: http://terminology.hl7.org/CodeSystem/v3-ActCode code PAT_ADV_EVNT = 'patient adverse event', stated as 'Patient Adverse Event')</p><h3>Destinations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Endpoint</b></td><td><b>Receiver</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"http://example.org/ZZFDA\">http://example.org/ZZFDA</a></td><td><a href=\"#Organization_FDA\">See above (Organization/FDA)</a></td></tr></table><p><b>sender</b>: <a href=\"#Organization_BESTPrototype\">See above (Organization/BESTPrototype)</a></p><h3>Sources</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Endpoint</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"http://example.org/BEST-Pilot\">http://example.org/BEST-Pilot</a></td></tr></table><p><b>reason</b>: Indicates receipt of a public health report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/us/medmorph/2021Jan/CodeSystem-us-ph-triggerdefinition-namedevents.html\">US Public Health TriggerDefinition Named Events</a>#received-public-health-report)</span></p><p><b>focus</b>: <a href=\"#Composition_TransfusionExample\">See above (Composition/TransfusionExample)</a></p></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/us/medmorph/StructureDefinition/ext-messageProcessingCategory"^^xsd:anyURI ] ;
fhir:value [ fhir:v "notification" ]
  ] ) ; # 
  fhir:event [
a fhir:Coding ;
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-ActCode"^^xsd:anyURI ] ;
fhir:code [ fhir:v "PAT_ADV_EVNT" ] ;
fhir:display [ fhir:v "Patient Adverse Event" ]
  ] ; # 
  fhir:destination ( [
fhir:endpoint [ fhir:v "http://example.org/ZZFDA"^^xsd:anyURI ] ;
fhir:receiver [
fhir:reference [ fhir:v "Organization/FDA" ]     ]
  ] ) ; # 
  fhir:sender [
fhir:reference [ fhir:v "Organization/BESTPrototype" ]
  ] ; # 
  fhir:source [
fhir:endpoint [ fhir:v "http://example.org/BEST-Pilot"^^xsd:anyURI ]
  ] ; # 
  fhir:reason [
    ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/us/medmorph/CodeSystem/us-ph-triggerdefinition-namedevents"^^xsd:anyURI ] ;
fhir:code [ fhir:v "received-public-health-report" ]     ] )
  ] ; # 
  fhir:focus ( [
fhir:reference [ fhir:v "Composition/TransfusionExample" ]
  ] ) . # 

<Composition/TransfusionExample> a fhir:Composition ;
  fhir:id [ fhir:v "TransfusionExample"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-composition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-composition>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Composition</b><a name=\"TransfusionExample\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Composition &quot;TransfusionExample&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-composition.html\">ICSR Composition</a></p></div><blockquote><p><b>AdditionalDocumentInformation</b></p><blockquote><p><b>url</b></p><code>availableFlag</code></blockquote><p><b>value</b>: false</p></blockquote><blockquote><p><b>ExpeditedReport</b></p><blockquote><p><b>url</b></p><code>localCriteriaFlag</code></blockquote><p><b>value</b>: false</p><blockquote><p><b>url</b></p><code>localCriteriaReportType</code></blockquote><p><b>value</b>: Non-Expedited AE <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#2)</span></p></blockquote><p><b>FirstSenderType</b>: Other <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#2)</span></p><p><b>CombinationProductReport</b>: false</p><p><b>FirstReceiveDate</b>: 2021-01-05</p><p><b>MostRecentDate</b>: 2021-01-05</p><p><b>CaseIdentifier</b>: id: BEST_beafb541-3eab-eb9e-1bf1-5fa477d56e77</p><p><b>identifier</b>: id: BEST_beafb541-3eab-eb9e-1bf1-5fa477d56e77</p><p><b>status</b>: final</p><p><b>type</b>: Adverse event note <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#85893-6)</span></p><p><b>category</b>: Spontaneous report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#1)</span></p><p><b>date</b>: 2021-01-05</p><p><b>author</b>: <a href=\"#PractitionerRole_BESTAuthorRole\">See above (PractitionerRole/BESTAuthorRole)</a></p><p><b>title</b>: ICSR Submission</p></div>"
  ] ; # 
  fhir:extension ( [
    ( fhir:extension [
fhir:url [ fhir:v "availableFlag"^^xsd:anyURI ] ;
fhir:value [ fhir:v "false"^^xsd:boolean ]     ] ) ;
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-additionaldocumentinformation"^^xsd:anyURI ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "localCriteriaFlag"^^xsd:anyURI ] ;
fhir:value [ fhir:v "false"^^xsd:boolean ]     ] [
fhir:url [ fhir:v "localCriteriaReportType"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.3.989.2.1.1.1003"^^xsd:anyURI ] ;
fhir:code [ fhir:v "2" ] ;
fhir:display [ fhir:v "Non-Expedited AE" ]         ] )       ]     ] ) ;
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-expeditedreport"^^xsd:anyURI ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-firstsendertype"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.3.989.2.1.1.3"^^xsd:anyURI ] ;
fhir:code [ fhir:v "2" ] ;
fhir:display [ fhir:v "Other" ]       ] )     ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-combinationproductreport"^^xsd:anyURI ] ;
fhir:value [ fhir:v "false"^^xsd:boolean ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-firstreceivedate"^^xsd:anyURI ] ;
fhir:value [ fhir:v "2021-01-05"^^xsd:date ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-mostrecentdate"^^xsd:anyURI ] ;
fhir:value [ fhir:v "2021-01-05"^^xsd:date ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-caseidentifier"^^xsd:anyURI ] ;
fhir:value [
a fhir:Identifier ;
fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.3.989.2.1.3.2"^^xsd:anyURI ] ;
fhir:value [ fhir:v "BEST_beafb541-3eab-eb9e-1bf1-5fa477d56e77" ]     ]
  ] ) ; # 
  fhir:identifier [
fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.3.989.2.1.3.1"^^xsd:anyURI ] ;
fhir:value [ fhir:v "BEST_beafb541-3eab-eb9e-1bf1-5fa477d56e77" ]
  ] ; # 
  fhir:status [ fhir:v "final"] ; # 
  fhir:type [
    ( fhir:coding [
a loinc:85893-6 ;
fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "85893-6" ] ;
fhir:display [ fhir:v "Adverse event note" ]     ] )
  ] ; # 
  fhir:category ( [
    ( fhir:coding [
fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.3.989.2.1.1.2"^^xsd:anyURI ] ;
fhir:code [ fhir:v "1" ] ;
fhir:display [ fhir:v "Spontaneous report" ]     ] )
  ] ) ; # 
  fhir:subject [
fhir:reference [ fhir:v "Patient/BESTPatient" ]
  ] ; # 
  fhir:date [ fhir:v "2021-01-05"^^xsd:date] ; # 
  fhir:author ( [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-authorprimarysource"^^xsd:anyURI ] ;
fhir:value [ fhir:v "true"^^xsd:boolean ]     ] ) ;
fhir:reference [ fhir:v "PractitionerRole/BESTAuthorRole" ]
  ] ) ; # 
  fhir:title [ fhir:v "ICSR Submission"] ; # 
  fhir:section ( [
fhir:title [ fhir:v "Reaction/Event" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ReactionEvent" ]       ] )     ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Allergic transfusion reaction</div>"     ] ;
    ( fhir:entry [
fhir:reference [ fhir:v "AdverseEvent/TransfusionExampleEvent" ]     ] )
  ] [
fhir:title [ fhir:v "Drug Information" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS"^^xsd:anyURI ] ;
fhir:code [ fhir:v "DrugInformation" ]       ] )     ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Description code for blood products: E7003, Blood group and type: N/A Blood processing type: Apheresis PLATELETS|ACD-A&gt;PAS-C/XX/20-24C|ResLeu:&amp;lt;5E6|2nd container</div>"     ] ;
    ( fhir:entry [
fhir:reference [ fhir:v "Procedure/TransfusionExampleTransfusion" ]     ] [
fhir:reference [ fhir:v "MedicationAdministration/TransfusionEpinephrine" ]     ] [
fhir:reference [ fhir:v "MedicationAdministration/TransfusionDiphenhydramine" ]     ] )
  ] [
fhir:title [ fhir:v "Case Summary Narrative" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS"^^xsd:anyURI ] ;
fhir:code [ fhir:v "CaseSummaryNarrative" ]       ] )     ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Header: FDA CBER BEST Automated AE Reporting Prototype Case BEST Detection Phenotype Algorithm: Phenotype link: rules-cd BEST Certainty: Definite BEST Severity: Non-Severe BEST Imputability: Probable Form Type: 3500 Contact Method: Email Adverse Event: 1 Center to which the case is being routed to: CBER Whether the case is being sent to DQRS: false Whether the report is related to drugs or food/cosmetics: 1 Whether the blood report is of type Transfusion or Collection: 2 Patient Race Code: 2f, Blood group of patient: N/A, Onset location for reaction: MedStar Location Description code for blood products: N/A, Blood group and type: N/A Blood processing type: N/A Product available for evaluation: 2 Volume of transfusion: NI NHSN Workup: NI Preliminary investigation results: Developed rash &amp;#38; stridor following transfusion prbc for anemia. Tx with benadryl &amp;#38; epinephrine &amp;#38; sx improved., Adverse Event Type Imputability: Blood Transfusion - Certainty: Definite; Notes: 1. notes, Eval+Plan Note, For admission to Hosp with Dx Anemia. Transfuse PRBC now., Date 20020109; 2. notes, Eval+Plan Note, Patient has developed a new maculopapular rash following transfusion. Will give Benadryl 25 mg., Date 20020109; 3. notes, Eval+Plan Note, New onset Stridor following transfusion. Will give Epinephrine .5mg, and do transfusion Rxn workup, Date 20020109; 4. notes, Eval+Plan Note, RN note - Administered Benadryl 25mg IV for skin sx. After 30 min pt. reports some improvement in skin symptoms, Date 20020109 Labs, Vitals, and Tests: 1. labs, Diastolic Blood Pressure, 75.918 mm[Hg], Date 20020109; 2. labs, Systolic Blood Pressure, 123.08 mm[Hg], Date 20020109; 3. labs, Physical findings of Skin, generalized rash, Date 20020109; 4. labs, Respiratory status finding, Stridor, Date 20020109; Illness at Time of Vaccination: 1. illness, Problem, Anemia, Date 20020109;</div>"     ]
  ] [
fhir:title [ fhir:v "Patient Information" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS"^^xsd:anyURI ] ;
fhir:code [ fhir:v "PatientInformation" ]       ] )     ] ;
    ( fhir:entry [
fhir:reference [ fhir:v "Observation/BESTPatientAgeGroup" ]     ] )
  ] [
fhir:title [ fhir:v "Relevant Medical History" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS"^^xsd:anyURI ] ;
fhir:code [ fhir:v "RelevantMedicalHistory" ]       ] )     ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">NI</div>"     ]
  ] ) . # 

<Organization/FDA> a fhir:Organization ;
  fhir:id [ fhir:v "FDA"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Organization</b><a name=\"FDA\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;FDA&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-messageorganization.html\">MessageHeader Organization</a></p></div><p><b>DepartmentName</b>: Office of Surveillance and Epidemiology</p><p><b>active</b>: true</p><p><b>type</b>: Regulatory Authority <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#2)</span></p><p><b>name</b>: FDA</p><p><b>telecom</b>: <a href=\"mailto:faersesub@fda.hhs.gov\">faersesub@fda.hhs.gov</a></p><p><b>address</b>: 10903 New Hampshire Avenue Silver Spring MD 20993 US </p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Transfusion </td></tr></table></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-departmentname"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Office of Surveillance and Epidemiology" ]
  ] ) ; # 
  fhir:active [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:type ( [
    ( fhir:coding [
fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.3.989.2.1.1.7"^^xsd:anyURI ] ;
fhir:code [ fhir:v "2" ] ;
fhir:display [ fhir:v "Regulatory Authority" ]     ] )
  ] ) ; # 
  fhir:name [ fhir:v "FDA"] ; # 
  fhir:telecom ( [
fhir:system [ fhir:v "email" ] ;
fhir:value [ fhir:v "faersesub@fda.hhs.gov" ]
  ] ) ; # 
  fhir:address ( [
    ( fhir:line [ fhir:v "10903 New Hampshire Avenue" ] ) ;
fhir:city [ fhir:v "Silver Spring" ] ;
fhir:state [ fhir:v "MD" ] ;
fhir:postalCode [ fhir:v "20993" ] ;
fhir:country [ fhir:v "US" ]
  ] ) ; # 
  fhir:contact ( [
fhir:name [
      ( fhir:given [ fhir:v "Transfusion" ] )     ]
  ] ) . # 

<Organization/BESTPrototype> a fhir:Organization ;
  fhir:id [ fhir:v "BESTPrototype"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Organization</b><a name=\"BESTPrototype\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;BESTPrototype&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-messageorganization.html\">MessageHeader Organization</a></p></div><p><b>active</b>: true</p><p><b>name</b>: BEST-Prototype</p></div>"
  ] ; # 
  fhir:active [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:name [ fhir:v "BEST-Prototype"] . # 

<PractitionerRole/BESTAuthorRole> a fhir:PractitionerRole ;
  fhir:id [ fhir:v "BESTAuthorRole"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitionerrole"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitionerrole>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: PractitionerRole</b><a name=\"BESTAuthorRole\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PractitionerRole &quot;BESTAuthorRole&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-authorpractitionerrole.html\">PractitionerRole Author</a></p></div><p><b>practitioner</b>: <a href=\"#Practitioner_BESTAuthor\">See above (Practitioner/BESTAuthor)</a></p><p><b>organization</b>: <a href=\"#Organization_BESTPrototype\">See above (Organization/BESTPrototype)</a></p><p><b>code</b>: Physician <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#1)</span></p><p><b>telecom</b>: <a href=\"mailto:admin@admin.com\">admin@admin.com</a></p></div>"
  ] ; # 
  fhir:practitioner [
fhir:reference [ fhir:v "Practitioner/BESTAuthor" ]
  ] ; # 
  fhir:organization [
fhir:reference [ fhir:v "Organization/BESTPrototype" ]
  ] ; # 
  fhir:code ( [
    ( fhir:coding [
fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.3.989.2.1.1.6"^^xsd:anyURI ] ;
fhir:code [ fhir:v "1" ] ;
fhir:display [ fhir:v "Physician" ]     ] )
  ] ) ; # 
  fhir:telecom ( [
fhir:system [ fhir:v "email" ] ;
fhir:value [ fhir:v "admin@admin.com" ]
  ] ) . # 

<Practitioner/BESTAuthor> a fhir:Practitioner ;
  fhir:id [ fhir:v "BESTAuthor"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitioner"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitioner>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Practitioner</b><a name=\"BESTAuthor\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Practitioner &quot;BESTAuthor&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-authorpractitioner.html\">Practitioner Author</a></p></div><p><b>identifier</b>: id: NI</p><p><b>name</b>: NI </p></div>"
  ] ; # 
  fhir:identifier ( [
fhir:system [ fhir:v "http://hl7.org/fhir/sid/us-npi"^^xsd:anyURI ] ;
fhir:value [ fhir:v "NI" ]
  ] ) ; # 
  fhir:name ( [
fhir:family [ fhir:v "NI" ]
  ] ) . # 

<Patient/BESTPatient> a fhir:Patient ;
  fhir:id [ fhir:v "BESTPatient"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patient"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patient>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Patient</b><a name=\"BESTPatient\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Patient &quot;BESTPatient&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-patient.html\">ICSR Patient</a></p></div><p><b>identifier</b>: id: 123456789</p><p><b>name</b>: CM </p><p><b>gender</b>: female</p><p><b>birthDate</b>: 1999-06-24</p></div>"
  ] ; # 
  fhir:identifier ( [
fhir:system [ fhir:v "http://hl7.org/fhir/sid/us-ssn"^^xsd:anyURI ] ;
fhir:value [ fhir:v "123456789" ]
  ] ) ; # 
  fhir:name ( [
fhir:family [ fhir:v "CM" ]
  ] ) ; # 
  fhir:gender [ fhir:v "female"] ; # 
  fhir:birthDate [ fhir:v "1999-06-24"^^xsd:date] . # 

<Observation/BESTPatientAgeGroup> a fhir:Observation ;
  fhir:id [ fhir:v "BESTPatientAgeGroup"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patientagegroup"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patientagegroup>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"BESTPatientAgeGroup\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;BESTPatientAgeGroup&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-patientagegroup.html\">Descriptive Age Group for the Patient</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Age group <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#46251-5)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>value</b>: Adult <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#5)</span></p></div>"
  ] ; # 
  fhir:status [ fhir:v "final"] ; # 
  fhir:code [
    ( fhir:coding [
a loinc:46251-5 ;
fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "46251-5" ] ;
fhir:display [ fhir:v "Age group" ]     ] )
  ] ; # 
  fhir:subject [
fhir:reference [ fhir:v "Patient/BESTPatient" ]
  ] ; # 
  fhir:value [
a fhir:CodeableConcept ;
    ( fhir:coding [
fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.3.989.2.1.1.9"^^xsd:anyURI ] ;
fhir:code [ fhir:v "5" ] ;
fhir:display [ fhir:v "Adult" ]     ] )
  ] . # 

<AdverseEvent/TransfusionExampleEvent> a fhir:AdverseEvent ;
  fhir:id [ fhir:v "TransfusionExampleEvent"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/transfusion-adverseevent"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/transfusion-adverseevent>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: AdverseEvent</b><a name=\"TransfusionExampleEvent\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource AdverseEvent &quot;TransfusionExampleEvent&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-transfusion-adverseevent.html\">Transfusion Adverse Event</a></p></div><p><b>AgeAtTimeOfOnset</b>: 1 a<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code a = 'a')</span></p><p><b>actuality</b>: actual</p><p><b>event</b>: Allergic transfusion reaction <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (meddra.org#10066173)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>date</b>: 2000-01-01</p><p><b>seriousness</b>: Serious <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-adverse-event-seriousness.html\">AdverseEventSeriousness</a>#serious)</span></p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#Procedure_TransfusionExampleTransfusion\">See above (Procedure/TransfusionExampleTransfusion)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ProductRelatedness</b></td></tr><tr><td style=\"display: none\">*</td><td>Suspect</td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_TransfusionEpinephrine\">See above (MedicationAdministration/TransfusionEpinephrine)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ProductRelatedness</b></td></tr><tr><td style=\"display: none\">*</td><td>Concomitant</td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_TransfusionDiphenhydramine\">See above (MedicationAdministration/TransfusionDiphenhydramine)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ProductRelatedness</b></td></tr><tr><td style=\"display: none\">*</td><td>Concomitant</td></tr></table></blockquote></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-ageattimeofonset"^^xsd:anyURI ] ;
fhir:value [
a fhir:Age ;
fhir:value [ fhir:v "1"^^xsd:decimal ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "a" ]     ]
  ] ) ; # 
  fhir:actuality [ fhir:v "actual"] ; # 
  fhir:event [
    ( fhir:coding [
fhir:system [ fhir:v "http://meddra.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "10066173" ] ;
fhir:display [ fhir:v "Allergic transfusion reaction" ]     ] )
  ] ; # 
  fhir:subject [
fhir:reference [ fhir:v "Patient/BESTPatient" ]
  ] ; # 
  fhir:date [
fhir:v "2000-01-01"^^xsd:date ;
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-eventenddate"^^xsd:anyURI ] ;
fhir:value [ fhir:v "2019-01-20"^^xsd:date ]     ] [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-eventduration"^^xsd:anyURI ] ;
fhir:value [
a fhir:Duration ;
fhir:value [ fhir:v "19.05"^^xsd:decimal ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "a" ]       ]     ] )
  ] ; # 
  fhir:seriousness [
    ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/adverse-event-seriousness"^^xsd:anyURI ] ;
fhir:code [ fhir:v "serious" ]     ] )
  ] ; # 
  fhir:suspectEntity ( [
fhir:instance [
fhir:reference [ fhir:v "Procedure/TransfusionExampleTransfusion" ]     ] ;
    ( fhir:causality [
fhir:productRelatedness [ fhir:v "Suspect" ]     ] )
  ] [
fhir:instance [
fhir:reference [ fhir:v "MedicationAdministration/TransfusionEpinephrine" ]     ] ;
    ( fhir:causality [
fhir:productRelatedness [ fhir:v "Concomitant" ]     ] )
  ] [
fhir:instance [
fhir:reference [ fhir:v "MedicationAdministration/TransfusionDiphenhydramine" ]     ] ;
    ( fhir:causality [
fhir:productRelatedness [ fhir:v "Concomitant" ]     ] )
  ] ) . # 

<Procedure/TransfusionExampleTransfusion> a fhir:Procedure ;
  fhir:id [ fhir:v "TransfusionExampleTransfusion"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-transfusion"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-transfusion>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Procedure</b><a name=\"TransfusionExampleTransfusion\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure &quot;TransfusionExampleTransfusion&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-transfusion.html\">ICSR Transfusion</a></p></div><p><b>UsedProductAmount</b>: 1 unit<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code {unit} = '{unit}')</span></p><p><b>status</b>: completed</p><p><b>code</b>: 36430 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-CPT.html\">Current Procedural Terminology (CPT®)</a>#36430)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>performed</b>: 2002-01-09</p><p><b>usedReference</b>: <span>: Apheresis PLATELETS|ACD-A&gt;PAS-C/XX/20-24C|ResLeu:&lt;5E6|2nd container</span></p></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-usedproductamount"^^xsd:anyURI ] ;
fhir:value [
a fhir:Quantity ;
fhir:value [ fhir:v "1"^^xsd:decimal ] ;
fhir:unit [ fhir:v "unit" ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "{unit}" ]     ]
  ] ) ; # 
  fhir:status [ fhir:v "completed"] ; # 
  fhir:code [
    ( fhir:coding [
fhir:system [ fhir:v "http://www.ama-assn.org/go/cpt"^^xsd:anyURI ] ;
fhir:code [ fhir:v "36430" ]     ] )
  ] ; # 
  fhir:subject [
fhir:reference [ fhir:v "Patient/BESTPatient" ]
  ] ; # 
  fhir:performed [ fhir:v "2002-01-09"^^xsd:date] ; # 
  fhir:usedReference ( [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-usedproduct"^^xsd:anyURI ] ;
fhir:value [
a fhir:Reference ;
fhir:reference [ fhir:v "BiologicallyDerivedProduct/TransfusionBloodProduct" ]       ]     ] ) ;
fhir:display [ fhir:v "Apheresis PLATELETS|ACD-A>PAS-C/XX/20-24C|ResLeu:<5E6|2nd container" ]
  ] ) . # 

<BiologicallyDerivedProduct/TransfusionBloodProduct> a fhir:BiologicallyDerivedProduct ;
  fhir:id [ fhir:v "TransfusionBloodProduct"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bloodproduct"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bloodproduct>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: BiologicallyDerivedProduct</b><a name=\"TransfusionBloodProduct\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource BiologicallyDerivedProduct &quot;TransfusionBloodProduct&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-bloodproduct.html\">ICSR Blood Product</a></p></div><p><b>productCategory</b>: cells</p><p><b>productCode</b>: Apheresis PLATELETS|ACD-A&gt;PAS-C/XX/20-24C|ResLeu:&lt;5E6|2nd container <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterminology#E7003)</span></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
  ] ; # 
  fhir:productCategory [ fhir:v "cells"] ; # 
  fhir:productCode [
    ( fhir:coding [
fhir:system [ fhir:v "https://iccbba.org/standardterminology"^^xsd:anyURI ] ;
fhir:code [ fhir:v "E7003" ] ;
fhir:display [ fhir:v "Apheresis PLATELETS|ACD-A>PAS-C/XX/20-24C|ResLeu:<5E6|2nd container" ]     ] )
  ] ; # 
  fhir:collection [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-donationIdentificationNumber"^^xsd:anyURI ] ;
fhir:value [
a fhir:Identifier ;
fhir:system [ fhir:v "http://example.org/bloodDonationNumber"^^xsd:anyURI ] ;
fhir:value [ fhir:v "G101610840386" ]       ]     ] )
  ] . # 

<MedicationAdministration/TransfusionEpinephrine> a fhir:MedicationAdministration ;
  fhir:id [ fhir:v "TransfusionEpinephrine"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: MedicationAdministration</b><a name=\"TransfusionEpinephrine\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationAdministration &quot;TransfusionEpinephrine&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-medicationadministration.html\">ICSR MedicationAdministration</a></p></div><p><b>status</b>: completed</p><p><b>medication</b>: Epinephrine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#3992)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>effective</b>: 2002-01-09</p></div>"
  ] ; # 
  fhir:status [ fhir:v "completed"] ; # 
  fhir:medication [
a fhir:CodeableConcept ;
    ( fhir:coding [
fhir:system [ fhir:v "http://www.nlm.nih.gov/research/umls/rxnorm"^^xsd:anyURI ] ;
fhir:code [ fhir:v "3992" ] ;
fhir:display [ fhir:v "Epinephrine" ]     ] )
  ] ; # 
  fhir:subject [
fhir:reference [ fhir:v "Patient/BESTPatient" ]
  ] ; # 
  fhir:effective [ fhir:v "2002-01-09"^^xsd:date] . # 

<MedicationAdministration/TransfusionDiphenhydramine> a fhir:MedicationAdministration ;
  fhir:id [ fhir:v "TransfusionDiphenhydramine"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: MedicationAdministration</b><a name=\"TransfusionDiphenhydramine\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationAdministration &quot;TransfusionDiphenhydramine&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-medicationadministration.html\">ICSR MedicationAdministration</a></p></div><p><b>status</b>: completed</p><p><b>medication</b>: Diphenhydramine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#3498)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>effective</b>: 2002-01-09</p></div>"
  ] ; # 
  fhir:status [ fhir:v "completed"] ; # 
  fhir:medication [
a fhir:CodeableConcept ;
    ( fhir:coding [
fhir:system [ fhir:v "http://www.nlm.nih.gov/research/umls/rxnorm"^^xsd:anyURI ] ;
fhir:code [ fhir:v "3498" ] ;
fhir:display [ fhir:v "Diphenhydramine" ]     ] )
  ] ; # 
  fhir:subject [
fhir:reference [ fhir:v "Patient/BESTPatient" ]
  ] ; # 
  fhir:effective [ fhir:v "2002-01-09"^^xsd:date] . #