Global Core Electronic Medicinal Product Information (ePI)
1.1.0 - trial-use International flag

Global Core Electronic Medicinal Product Information (ePI), published by HL7 International - Biomedical Research & Regulation Work Group. This guide is not an authorized publication; it is the continuous build for version 1.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/emedicinal-product-info/ and changes regularly. See the Directory of published versions

: bundle-epi-type2-example-acetaminophen

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<Bundle xmlns="http://hl7.org/fhir">
  <id value="bundle-epi-type2-example-acetaminophen"/>
  <language value="en"/>
  <identifier>
    <system value="http://ema.europa.eu/identifier"/>
    <value value="WONDERDRUG-500MG-BUNDLE"/>
  </identifier>
  <type value="document"/>
  <timestamp value="2023-01-25T12:00:00Z"/>
  <entry>
    <fullUrl
             value="http://hl7.org/fhir/uv/emedicinal-product-info/Composition/composition-epi-type2-example-acetaminophen"/>
    <resource>
      <Composition>
        <id value="composition-epi-type2-example-acetaminophen"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Composition_composition-epi-type2-example-acetaminophen"> </a><p class="res-header-id"><b>Generated Narrative: Composition composition-epi-type2-example-acetaminophen</b></p><a name="composition-epi-type2-example-acetaminophen"> </a><a name="hccomposition-epi-type2-example-acetaminophen"> </a><p><b>status</b>: Final</p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi/ 100000155538}">Package Leaflet</span></p><p><b>date</b>: 2023-01-25</p><p><b>author</b>: <a href="Bundle-bundle-epi-type2-example-acetaminophen.html#Organization_org-epi-type2-example-acme">Organization Acme Pharma Inc.</a></p><p><b>title</b>: Package Leaflet: Information for the user - WonderDrug 500 mg tablets</p></div>
        </text>
        <status value="final"/>
        <type>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi/"/>
            <code value="100000155538"/>
          </coding>
          <text value="Package Leaflet"/>
        </type>
        <subject>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen"/>
        </subject>
        <subject>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen-100mg"/>
        </subject>
        <subject>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen-200mg"/>
        </subject>
        <date value="2023-01-25"/>
        <author>
          <reference value="Organization/org-epi-type2-example-acme"/>
        </author>
        <title
               value="Package Leaflet: Information for the user - WonderDrug 500 mg tablets"/>
        <section>
          <title value="1. What is in this leaflet"/>
          <code>
            <coding>
              <system value="https://spor.ema.europa.eu/rmswi/"/>
              <code value="100000155538"/>
            </coding>
            <text value="1. What is in this leaflet"/>
          </code>
          <text>
            <status value="generated"/>
            <div xmlns="http://www.w3.org/1999/xhtml"><h2>1. What is in this leaflet</h2><p>Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.</p></div>
          </text>
        </section>
      </Composition>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://hl7.org/fhir/uv/emedicinal-product-info/Organization/org-epi-type2-example-acme"/>
    <resource>
      <Organization>
        <id value="org-epi-type2-example-acme"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_org-epi-type2-example-acme"> </a><p class="res-header-id"><b>Generated Narrative: Organization org-epi-type2-example-acme</b></p><a name="org-epi-type2-example-acme"> </a><a name="hcorg-epi-type2-example-acme"> </a><p><b>identifier</b>: <code>https://spor.ema.europa.eu/omswi</code>/LOC-100000000</p><p><b>active</b>: true</p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 220000000034}">Marketing authorisation holder</span></p><p><b>name</b>: Acme Pharma Inc.</p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Address</b></td></tr><tr><td style="display: none">*</td><td>123 Pharma Way, 102 37 Prague 10, Czech Republic</td></tr></table></div>
        </text>
        <identifier>
          <system value="https://spor.ema.europa.eu/omswi"/>
          <value value="LOC-100000000"/>
        </identifier>
        <active value="true"/>
        <type>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="220000000034"/>
            <display value="Marketing authorisation holder"/>
          </coding>
        </type>
        <name value="Acme Pharma Inc."/>
        <contact>
          <address>
            <text value="123 Pharma Way, 102 37 Prague 10, Czech Republic"/>
            <line value="123 Pharma Way"/>
            <city value="Prague"/>
            <postalCode value="102 37"/>
            <country value="Czech Republic"/>
          </address>
        </contact>
      </Organization>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://hl7.org/fhir/uv/emedicinal-product-info/MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen"/>
    <resource>
      <MedicinalProductDefinition>
        <id value="mpd-epi-type2-example-acetaminophen"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen"> </a><p class="res-header-id"><b>Generated Narrative: MedicinalProductDefinition mpd-epi-type2-example-acetaminophen</b></p><a name="mpd-epi-type2-example-acetaminophen"> </a><a name="hcmpd-epi-type2-example-acetaminophen"> </a><p><b>identifier</b>: <code>http://ema.europa.eu/identifier</code>/WONDERDRUG-500MG</p><p><b>domain</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-domain Human}">Human use</span></p><p><b>status</b>: <span title="Codes:{http://hl7.org/fhir/publication-status active}">Active</span></p><p><b>legalStatusOfSupply</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000072084}">Medicinal product subject to medical prescription</span></p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Contact</b></td></tr><tr><td style="display: none">*</td><td><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#Organization_org-epi-type2-example-acme">Organization Acme Pharma Inc.</a></td></tr></table><blockquote><p><b>name</b></p><p><b>productName</b>: WonderDrug 500 mg tablets</p><blockquote><p><b>part</b></p><p><b>part</b>: WonderDrug</p><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-name-part-type INV}">Invented Name Part</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: 500 mg</p><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-name-part-type STR}">Strength part</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: tablets</p><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-name-part-type FRM}">Form part</span></p></blockquote><h3>Usages</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Country</b></td><td><b>Language</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://hl7.org/fhir/country EE}">Estonia</span></td><td><span title="Codes:{urn:ietf:bcp:47 et}">Estonian</span></td></tr></table></blockquote></div>
        </text>
        <identifier>
          <system value="http://ema.europa.eu/identifier"/>
          <value value="WONDERDRUG-500MG"/>
        </identifier>
        <domain>
          <coding>
            <system value="http://hl7.org/fhir/medicinal-product-domain"/>
            <code value="Human"/>
            <display value="Human use"/>
          </coding>
        </domain>
        <status>
          <coding>
            <system value="http://hl7.org/fhir/publication-status"/>
            <code value="active"/>
            <display value="Active"/>
          </coding>
        </status>
        <legalStatusOfSupply>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="100000072084"/>
            <display
                     value="Medicinal product subject to medical prescription"/>
          </coding>
        </legalStatusOfSupply>
        <contact>
          <contact>
            <reference value="Organization/org-epi-type2-example-acme"/>
          </contact>
        </contact>
        <name>
          <productName value="WonderDrug 500 mg tablets"/>
          <part>
            <part value="WonderDrug"/>
            <type>
              <coding>
                <system
                        value="http://hl7.org/fhir/medicinal-product-name-part-type"/>
                <code value="INV"/>
                <display value="Invented Name Part"/>
              </coding>
            </type>
          </part>
          <part>
            <part value="500 mg"/>
            <type>
              <coding>
                <system
                        value="http://hl7.org/fhir/medicinal-product-name-part-type"/>
                <code value="STR"/>
                <display value="Strength part"/>
              </coding>
            </type>
          </part>
          <part>
            <part value="tablets"/>
            <type>
              <coding>
                <system
                        value="http://hl7.org/fhir/medicinal-product-name-part-type"/>
                <code value="FRM"/>
                <display value="Form part"/>
              </coding>
            </type>
          </part>
          <usage>
            <country>
              <coding>
                <system value="http://hl7.org/fhir/country"/>
                <code value="EE"/>
                <display value="Estonia"/>
              </coding>
            </country>
            <language>
              <coding>
                <system value="urn:ietf:bcp:47"/>
                <code value="et"/>
                <display value="Estonian"/>
              </coding>
            </language>
          </usage>
        </name>
      </MedicinalProductDefinition>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://hl7.org/fhir/uv/emedicinal-product-info/RegulatedAuthorization/ra-epi-type2-example-acetaminophen"/>
    <resource>
      <RegulatedAuthorization>
        <id value="ra-epi-type2-example-acetaminophen"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="RegulatedAuthorization_ra-epi-type2-example-acetaminophen"> </a><p class="res-header-id"><b>Generated Narrative: RegulatedAuthorization ra-epi-type2-example-acetaminophen</b></p><a name="ra-epi-type2-example-acetaminophen"> </a><a name="hcra-epi-type2-example-acetaminophen"> </a><p><b>identifier</b>: <code>http://ema.europa.eu/identifier</code>/MA-123456789</p><p><b>subject</b>: <a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-500MG; domain = Human use; status = Active; legalStatusOfSupply = Medicinal product subject to medical prescription</a></p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 220000000061}">Marketing Authorisation</span></p><p><b>region</b>: <span title="Codes:{http://hl7.org/fhir/country EE}">Estonia</span></p><p><b>holder</b>: <a href="Bundle-bundle-epi-type2-example-acetaminophen.html#Organization_org-epi-type2-example-acme">Organization Acme Pharma Inc.</a></p></div>
        </text>
        <identifier>
          <system value="http://ema.europa.eu/identifier"/>
          <value value="MA-123456789"/>
        </identifier>
        <subject>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen"/>
        </subject>
        <type>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="220000000061"/>
            <display value="Marketing Authorisation"/>
          </coding>
        </type>
        <region>
          <coding>
            <system value="http://hl7.org/fhir/country"/>
            <code value="EE"/>
            <display value="Estonia"/>
          </coding>
        </region>
        <holder>
          <reference value="Organization/org-epi-type2-example-acme"/>
        </holder>
      </RegulatedAuthorization>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://hl7.org/fhir/uv/emedicinal-product-info/PackagedProductDefinition/ppd-epi-type2-example-acetaminophen"/>
    <resource>
      <PackagedProductDefinition>
        <id value="ppd-epi-type2-example-acetaminophen"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="PackagedProductDefinition_ppd-epi-type2-example-acetaminophen"> </a><p class="res-header-id"><b>Generated Narrative: PackagedProductDefinition ppd-epi-type2-example-acetaminophen</b></p><a name="ppd-epi-type2-example-acetaminophen"> </a><a name="hcppd-epi-type2-example-acetaminophen"> </a><p><b>packageFor</b>: <a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-500MG; domain = Human use; status = Active; legalStatusOfSupply = Medicinal product subject to medical prescription</a></p><blockquote><p><b>packaging</b></p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073498}">Box</span></p><p><b>quantity</b>: 1</p><blockquote><p><b>packaging</b></p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073496}">Blister</span></p><blockquote><p><b>containedItem</b></p><h3>Items</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#ManufacturedItemDefinition_mid-epi-type2-example-acetaminophen">ManufacturedItemDefinition: status = active; manufacturedDoseForm = Tablet; unitOfPresentation = Tablet</a></td></tr></table><p><b>amount</b>: 30 Tablet</p></blockquote></blockquote></blockquote></div>
        </text>
        <packageFor>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen"/>
        </packageFor>
        <packaging>
          <type>
            <coding>
              <system value="https://spor.ema.europa.eu/rmswi"/>
              <code value="100000073498"/>
              <display value="Box"/>
            </coding>
          </type>
          <quantity value="1"/>
          <packaging>
            <type>
              <coding>
                <system value="https://spor.ema.europa.eu/rmswi"/>
                <code value="100000073496"/>
                <display value="Blister"/>
              </coding>
            </type>
            <containedItem>
              <item>
                <reference>
                  <reference
                             value="ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen"/>
                </reference>
              </item>
              <amount>
                <value value="30"/>
                <unit value="Tablet"/>
                <system
                        value="http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/unit-of-presentation"/>
              </amount>
            </containedItem>
          </packaging>
        </packaging>
      </PackagedProductDefinition>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://hl7.org/fhir/uv/emedicinal-product-info/ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen"/>
    <resource>
      <ManufacturedItemDefinition>
        <id value="mid-epi-type2-example-acetaminophen"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="ManufacturedItemDefinition_mid-epi-type2-example-acetaminophen"> </a><p class="res-header-id"><b>Generated Narrative: ManufacturedItemDefinition mid-epi-type2-example-acetaminophen</b></p><a name="mid-epi-type2-example-acetaminophen"> </a><a name="hcmid-epi-type2-example-acetaminophen"> </a><p><b>status</b>: Active</p><p><b>manufacturedDoseForm</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073664}">Tablet</span></p><p><b>unitOfPresentation</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 200000002152}">Tablet</span></p><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:">colour</span></td><td><span title="Codes:{http://hl7.org/fhir/colour white}">White</span></td></tr></table></div>
        </text>
        <status value="active"/>
        <manufacturedDoseForm>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="100000073664"/>
            <display value="Tablet"/>
          </coding>
        </manufacturedDoseForm>
        <unitOfPresentation>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="200000002152"/>
            <display value="Tablet"/>
          </coding>
        </unitOfPresentation>
        <property>
          <type>
            <coding>
              <code value="colour"/>
            </coding>
          </type>
          <valueCodeableConcept>
            <coding>
              <system value="http://hl7.org/fhir/colour"/>
              <code value="white"/>
              <display value="White"/>
            </coding>
          </valueCodeableConcept>
        </property>
      </ManufacturedItemDefinition>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://hl7.org/fhir/uv/emedicinal-product-info/AdministrableProductDefinition/apd-epi-type2-example-acetaminophen"/>
    <resource>
      <AdministrableProductDefinition>
        <id value="apd-epi-type2-example-acetaminophen"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="AdministrableProductDefinition_apd-epi-type2-example-acetaminophen"> </a><p class="res-header-id"><b>Generated Narrative: AdministrableProductDefinition apd-epi-type2-example-acetaminophen</b></p><a name="apd-epi-type2-example-acetaminophen"> </a><a name="hcapd-epi-type2-example-acetaminophen"> </a><p><b>status</b>: Active</p><p><b>formOf</b>: <a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-500MG; domain = Human use; status = Active; legalStatusOfSupply = Medicinal product subject to medical prescription</a></p><p><b>administrableDoseForm</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073664}">Tablet</span></p><p><b>unitOfPresentation</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 200000002152}">Tablet</span></p><p><b>producedFrom</b>: <a href="Bundle-bundle-epi-type2-example-acetaminophen.html#ManufacturedItemDefinition_mid-epi-type2-example-acetaminophen">ManufacturedItemDefinition: status = active; manufacturedDoseForm = Tablet; unitOfPresentation = Tablet</a></p><h3>RouteOfAdministrations</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073619}">Oral use</span></td></tr></table></div>
        </text>
        <status value="active"/>
        <formOf>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen"/>
        </formOf>
        <administrableDoseForm>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="100000073664"/>
            <display value="Tablet"/>
          </coding>
        </administrableDoseForm>
        <unitOfPresentation>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="200000002152"/>
            <display value="Tablet"/>
          </coding>
        </unitOfPresentation>
        <producedFrom>
          <reference
                     value="ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen"/>
        </producedFrom>
        <routeOfAdministration>
          <code>
            <coding>
              <system value="https://spor.ema.europa.eu/rmswi"/>
              <code value="100000073619"/>
              <display value="Oral use"/>
            </coding>
          </code>
        </routeOfAdministration>
      </AdministrableProductDefinition>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://hl7.org/fhir/uv/emedicinal-product-info/Ingredient/ingredient-epi-type2-example-acetaminophen-active"/>
    <resource>
      <Ingredient>
        <id value="ingredient-epi-type2-example-acetaminophen-active"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Ingredient_ingredient-epi-type2-example-acetaminophen-active"> </a><p class="res-header-id"><b>Generated Narrative: Ingredient ingredient-epi-type2-example-acetaminophen-active</b></p><a name="ingredient-epi-type2-example-acetaminophen-active"> </a><a name="hcingredient-epi-type2-example-acetaminophen-active"> </a><p><b>status</b>: Active</p><p><b>for</b>: </p><ul><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-500MG; domain = Human use; status = Active; legalStatusOfSupply = Medicinal product subject to medical prescription</a></li><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#ManufacturedItemDefinition_mid-epi-type2-example-acetaminophen">ManufacturedItemDefinition: status = active; manufacturedDoseForm = Tablet; unitOfPresentation = Tablet</a></li><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#AdministrableProductDefinition_apd-epi-type2-example-acetaminophen">AdministrableProductDefinition: status = active; administrableDoseForm = Tablet; unitOfPresentation = Tablet</a></li></ul><p><b>role</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000072072}">Active</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Concept</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{https://spor.ema.europa.eu/smswi 100000000000}">Paracetamol</span></td></tr></table><h3>Strengths</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Presentation[x]</b></td></tr><tr><td style="display: none">*</td><td>500 mg<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemg = 'mg')</span>/1 tablet<span style="background: LightGoldenRodYellow"> (Details: unit-of-presentation  codetablet = 'tablet')</span></td></tr></table></blockquote></div>
        </text>
        <status value="active"/>
        <for>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen"/>
        </for>
        <for>
          <reference
                     value="ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen"/>
        </for>
        <for>
          <reference
                     value="AdministrableProductDefinition/apd-epi-type2-example-acetaminophen"/>
        </for>
        <role>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="100000072072"/>
            <display value="Active"/>
          </coding>
        </role>
        <substance>
          <code>
            <concept>
              <coding>
                <system value="https://spor.ema.europa.eu/smswi"/>
                <code value="100000000000"/>
                <display value="Paracetamol"/>
              </coding>
            </concept>
          </code>
          <strength>
            <presentationRatio>
              <numerator>
                <value value="500"/>
                <unit value="mg"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="mg"/>
              </numerator>
              <denominator>
                <value value="1"/>
                <unit value="tablet"/>
                <system
                        value="http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/unit-of-presentation"/>
                <code value="tablet"/>
              </denominator>
            </presentationRatio>
          </strength>
        </substance>
      </Ingredient>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://hl7.org/fhir/uv/emedicinal-product-info/Ingredient/ingredient-epi-type2-example-acetaminophen-excipient-1"/>
    <resource>
      <Ingredient>
        <id value="ingredient-epi-type2-example-acetaminophen-excipient-1"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Ingredient_ingredient-epi-type2-example-acetaminophen-excipient-1"> </a><p class="res-header-id"><b>Generated Narrative: Ingredient ingredient-epi-type2-example-acetaminophen-excipient-1</b></p><a name="ingredient-epi-type2-example-acetaminophen-excipient-1"> </a><a name="hcingredient-epi-type2-example-acetaminophen-excipient-1"> </a><p><b>status</b>: Active</p><p><b>for</b>: </p><ul><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-500MG; domain = Human use; status = Active; legalStatusOfSupply = Medicinal product subject to medical prescription</a></li><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#ManufacturedItemDefinition_mid-epi-type2-example-acetaminophen">ManufacturedItemDefinition: status = active; manufacturedDoseForm = Tablet; unitOfPresentation = Tablet</a></li><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#AdministrableProductDefinition_apd-epi-type2-example-acetaminophen">AdministrableProductDefinition: status = active; administrableDoseForm = Tablet; unitOfPresentation = Tablet</a></li></ul><p><b>role</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000072082}">Excipient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Concept</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{https://spor.ema.europa.eu/smswi 100000000001}">Pregelatinised starch</span></td></tr></table></blockquote></div>
        </text>
        <status value="active"/>
        <for>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen"/>
        </for>
        <for>
          <reference
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        </for>
        <for>
          <reference
                     value="AdministrableProductDefinition/apd-epi-type2-example-acetaminophen"/>
        </for>
        <role>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="100000072082"/>
            <display value="Excipient"/>
          </coding>
        </role>
        <substance>
          <code>
            <concept>
              <coding>
                <system value="https://spor.ema.europa.eu/smswi"/>
                <code value="100000000001"/>
                <display value="Pregelatinised starch"/>
              </coding>
            </concept>
          </code>
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  </entry>
  <entry>
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             value="http://hl7.org/fhir/uv/emedicinal-product-info/Ingredient/ingredient-epi-type2-example-acetaminophen-excipient-2"/>
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      <Ingredient>
        <id value="ingredient-epi-type2-example-acetaminophen-excipient-2"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Ingredient_ingredient-epi-type2-example-acetaminophen-excipient-2"> </a><p class="res-header-id"><b>Generated Narrative: Ingredient ingredient-epi-type2-example-acetaminophen-excipient-2</b></p><a name="ingredient-epi-type2-example-acetaminophen-excipient-2"> </a><a name="hcingredient-epi-type2-example-acetaminophen-excipient-2"> </a><p><b>status</b>: Active</p><p><b>for</b>: </p><ul><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-500MG; domain = Human use; status = Active; legalStatusOfSupply = Medicinal product subject to medical prescription</a></li><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#ManufacturedItemDefinition_mid-epi-type2-example-acetaminophen">ManufacturedItemDefinition: status = active; manufacturedDoseForm = Tablet; unitOfPresentation = Tablet</a></li><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#AdministrableProductDefinition_apd-epi-type2-example-acetaminophen">AdministrableProductDefinition: status = active; administrableDoseForm = Tablet; unitOfPresentation = Tablet</a></li></ul><p><b>role</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000072082}">Excipient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Concept</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{https://spor.ema.europa.eu/smswi 100000000002}">Maize starch</span></td></tr></table></blockquote></div>
        </text>
        <status value="active"/>
        <for>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen"/>
        </for>
        <for>
          <reference
                     value="ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen"/>
        </for>
        <for>
          <reference
                     value="AdministrableProductDefinition/apd-epi-type2-example-acetaminophen"/>
        </for>
        <role>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="100000072082"/>
            <display value="Excipient"/>
          </coding>
        </role>
        <substance>
          <code>
            <concept>
              <coding>
                <system value="https://spor.ema.europa.eu/smswi"/>
                <code value="100000000002"/>
                <display value="Maize starch"/>
              </coding>
            </concept>
          </code>
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    </resource>
  </entry>
  <entry>
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             value="http://hl7.org/fhir/uv/emedicinal-product-info/Ingredient/ingredient-epi-type2-example-acetaminophen-excipient-3"/>
    <resource>
      <Ingredient>
        <id value="ingredient-epi-type2-example-acetaminophen-excipient-3"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Ingredient_ingredient-epi-type2-example-acetaminophen-excipient-3"> </a><p class="res-header-id"><b>Generated Narrative: Ingredient ingredient-epi-type2-example-acetaminophen-excipient-3</b></p><a name="ingredient-epi-type2-example-acetaminophen-excipient-3"> </a><a name="hcingredient-epi-type2-example-acetaminophen-excipient-3"> </a><p><b>status</b>: Active</p><p><b>for</b>: </p><ul><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-500MG; domain = Human use; status = Active; legalStatusOfSupply = Medicinal product subject to medical prescription</a></li><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#ManufacturedItemDefinition_mid-epi-type2-example-acetaminophen">ManufacturedItemDefinition: status = active; manufacturedDoseForm = Tablet; unitOfPresentation = Tablet</a></li><li><a href="Bundle-bundle-epi-type2-example-acetaminophen.html#AdministrableProductDefinition_apd-epi-type2-example-acetaminophen">AdministrableProductDefinition: status = active; administrableDoseForm = Tablet; unitOfPresentation = Tablet</a></li></ul><p><b>role</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000072082}">Excipient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Concept</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{https://spor.ema.europa.eu/smswi 100000000003}">Magnesium stearate</span></td></tr></table></blockquote></div>
        </text>
        <status value="active"/>
        <for>
          <reference
                     value="MedicinalProductDefinition/mpd-epi-type2-example-acetaminophen"/>
        </for>
        <for>
          <reference
                     value="ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen"/>
        </for>
        <for>
          <reference
                     value="AdministrableProductDefinition/apd-epi-type2-example-acetaminophen"/>
        </for>
        <role>
          <coding>
            <system value="https://spor.ema.europa.eu/rmswi"/>
            <code value="100000072082"/>
            <display value="Excipient"/>
          </coding>
        </role>
        <substance>
          <code>
            <concept>
              <coding>
                <system value="https://spor.ema.europa.eu/smswi"/>
                <code value="100000000003"/>
                <display value="Magnesium stearate"/>
              </coding>
            </concept>
          </code>
        </substance>
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  </entry>
  <entry>
    <resource>
      <MedicinalProductDefinition>
        <id value="mpd-epi-type2-example-acetaminophen-100mg"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen-100mg"> </a><p class="res-header-id"><b>Generated Narrative: MedicinalProductDefinition mpd-epi-type2-example-acetaminophen-100mg</b></p><a name="mpd-epi-type2-example-acetaminophen-100mg"> </a><a name="hcmpd-epi-type2-example-acetaminophen-100mg"> </a><p><b>identifier</b>: <code>http://ema.europa.eu/identifier</code>/WONDERDRUG-100MG</p><blockquote><p><b>name</b></p><p><b>productName</b>: WonderDrug 100 mg tablets</p><blockquote><p><b>part</b></p><p><b>part</b>: WonderDrug</p><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-name-part-type INV}">Invented Name Part</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: 100 mg</p><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-name-part-type STR}">Strength part</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: tablets</p><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-name-part-type FRM}">Form part</span></p></blockquote></blockquote></div>
        </text>
        <identifier>
          <system value="http://ema.europa.eu/identifier"/>
          <value value="WONDERDRUG-100MG"/>
        </identifier>
        <name>
          <productName value="WonderDrug 100 mg tablets"/>
          <part>
            <part value="WonderDrug"/>
            <type>
              <coding>
                <system
                        value="http://hl7.org/fhir/medicinal-product-name-part-type"/>
                <code value="INV"/>
                <display value="Invented Name Part"/>
              </coding>
            </type>
          </part>
          <part>
            <part value="100 mg"/>
            <type>
              <coding>
                <system
                        value="http://hl7.org/fhir/medicinal-product-name-part-type"/>
                <code value="STR"/>
                <display value="Strength part"/>
              </coding>
            </type>
          </part>
          <part>
            <part value="tablets"/>
            <type>
              <coding>
                <system
                        value="http://hl7.org/fhir/medicinal-product-name-part-type"/>
                <code value="FRM"/>
                <display value="Form part"/>
              </coding>
            </type>
          </part>
        </name>
      </MedicinalProductDefinition>
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  </entry>
  <entry>
    <resource>
      <PackagedProductDefinition>
        <id value="ppd-epi-type2-example-acetaminophen-100mg-1"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="PackagedProductDefinition_ppd-epi-type2-example-acetaminophen-100mg-1"> </a><p class="res-header-id"><b>Generated Narrative: PackagedProductDefinition ppd-epi-type2-example-acetaminophen-100mg-1</b></p><a name="ppd-epi-type2-example-acetaminophen-100mg-1"> </a><a name="hcppd-epi-type2-example-acetaminophen-100mg-1"> </a><p><b>packageFor</b>: <a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen-100mg">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-100MG</a></p><blockquote><p><b>packaging</b></p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073498}">Box</span></p><p><b>quantity</b>: 1</p><blockquote><p><b>packaging</b></p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073496}">Blister</span></p><p><b>quantity</b>: 2</p><blockquote><p><b>containedItem</b></p><h3>Items</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen-100mg">ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen-100mg</a></td></tr></table><p><b>amount</b>: 60 Tablet</p></blockquote></blockquote></blockquote></div>
        </text>
        <packageFor>
          <reference
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        </packageFor>
        <packaging>
          <type>
            <coding>
              <system value="https://spor.ema.europa.eu/rmswi"/>
              <code value="100000073498"/>
              <display value="Box"/>
            </coding>
          </type>
          <quantity value="1"/>
          <packaging>
            <type>
              <coding>
                <system value="https://spor.ema.europa.eu/rmswi"/>
                <code value="100000073496"/>
                <display value="Blister"/>
              </coding>
            </type>
            <quantity value="2"/>
            <containedItem>
              <item>
                <reference>
                  <reference
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                </reference>
              </item>
              <amount>
                <value value="60"/>
                <unit value="Tablet"/>
                <system
                        value="http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/unit-of-presentation"/>
              </amount>
            </containedItem>
          </packaging>
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  </entry>
  <entry>
    <resource>
      <PackagedProductDefinition>
        <id value="ppd-epi-type2-example-acetaminophen-100mg-2"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="PackagedProductDefinition_ppd-epi-type2-example-acetaminophen-100mg-2"> </a><p class="res-header-id"><b>Generated Narrative: PackagedProductDefinition ppd-epi-type2-example-acetaminophen-100mg-2</b></p><a name="ppd-epi-type2-example-acetaminophen-100mg-2"> </a><a name="hcppd-epi-type2-example-acetaminophen-100mg-2"> </a><p><b>packageFor</b>: <a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen-100mg">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-100MG</a></p><blockquote><p><b>packaging</b></p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073498}">Box</span></p><p><b>quantity</b>: 1</p><blockquote><p><b>packaging</b></p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073497}">Bottle</span></p><blockquote><p><b>containedItem</b></p><h3>Items</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen-100mg">ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen-100mg</a></td></tr></table><p><b>amount</b>: 30 Tablet</p></blockquote></blockquote></blockquote></div>
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              <system value="https://spor.ema.europa.eu/rmswi"/>
              <code value="100000073498"/>
              <display value="Box"/>
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          <quantity value="1"/>
          <packaging>
            <type>
              <coding>
                <system value="https://spor.ema.europa.eu/rmswi"/>
                <code value="100000073497"/>
                <display value="Bottle"/>
              </coding>
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            <containedItem>
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                  <reference
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                </reference>
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              <amount>
                <value value="30"/>
                <unit value="Tablet"/>
                <system
                        value="http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/unit-of-presentation"/>
              </amount>
            </containedItem>
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  </entry>
  <entry>
    <resource>
      <MedicinalProductDefinition>
        <id value="mpd-epi-type2-example-acetaminophen-200mg"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen-200mg"> </a><p class="res-header-id"><b>Generated Narrative: MedicinalProductDefinition mpd-epi-type2-example-acetaminophen-200mg</b></p><a name="mpd-epi-type2-example-acetaminophen-200mg"> </a><a name="hcmpd-epi-type2-example-acetaminophen-200mg"> </a><p><b>identifier</b>: <code>http://ema.europa.eu/identifier</code>/WONDERDRUG-200MG</p><blockquote><p><b>name</b></p><p><b>productName</b>: WonderDrug 200 mg tablets</p><blockquote><p><b>part</b></p><p><b>part</b>: WonderDrug</p><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-name-part-type INV}">Invented Name Part</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: 200 mg</p><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-name-part-type STR}">Strength part</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: tablets</p><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/medicinal-product-name-part-type FRM}">Form part</span></p></blockquote></blockquote></div>
        </text>
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          <system value="http://ema.europa.eu/identifier"/>
          <value value="WONDERDRUG-200MG"/>
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          <productName value="WonderDrug 200 mg tablets"/>
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            <part value="WonderDrug"/>
            <type>
              <coding>
                <system
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                <code value="INV"/>
                <display value="Invented Name Part"/>
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          <part>
            <part value="200 mg"/>
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              <coding>
                <system
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                <code value="STR"/>
                <display value="Strength part"/>
              </coding>
            </type>
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          <part>
            <part value="tablets"/>
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              <coding>
                <system
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                <code value="FRM"/>
                <display value="Form part"/>
              </coding>
            </type>
          </part>
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  <entry>
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        <id value="ppd-epi-type2-example-acetaminophen-200mg-1"/>
        <language value="en"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="PackagedProductDefinition_ppd-epi-type2-example-acetaminophen-200mg-1"> </a><p class="res-header-id"><b>Generated Narrative: PackagedProductDefinition ppd-epi-type2-example-acetaminophen-200mg-1</b></p><a name="ppd-epi-type2-example-acetaminophen-200mg-1"> </a><a name="hcppd-epi-type2-example-acetaminophen-200mg-1"> </a><p><b>packageFor</b>: <a href="Bundle-bundle-epi-type2-example-acetaminophen.html#MedicinalProductDefinition_mpd-epi-type2-example-acetaminophen-200mg">MedicinalProductDefinition: identifier = http://ema.europa.eu/identifier#WONDERDRUG-200MG</a></p><blockquote><p><b>packaging</b></p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073498}">Box</span></p><p><b>quantity</b>: 1</p><blockquote><p><b>packaging</b></p><p><b>type</b>: <span title="Codes:{https://spor.ema.europa.eu/rmswi 100000073496}">Blister</span></p><p><b>quantity</b>: 2</p><blockquote><p><b>containedItem</b></p><h3>Items</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen-200mg">ManufacturedItemDefinition/mid-epi-type2-example-acetaminophen-200mg</a></td></tr></table><p><b>amount</b>: 20 Tablet</p></blockquote></blockquote></blockquote></div>
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        <packageFor>
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              <system value="https://spor.ema.europa.eu/rmswi"/>
              <code value="100000073498"/>
              <display value="Box"/>
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          <quantity value="1"/>
          <packaging>
            <type>
              <coding>
                <system value="https://spor.ema.europa.eu/rmswi"/>
                <code value="100000073496"/>
                <display value="Blister"/>
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            <quantity value="2"/>
            <containedItem>
              <item>
                <reference>
                  <reference
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              <amount>
                <value value="20"/>
                <unit value="Tablet"/>
                <system
                        value="http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/unit-of-presentation"/>
              </amount>
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  <entry>
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