Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
| Official URL: https://fevir.net/resources/Evidence/557022 | Version: 1.0.0-ballot3 | ||||
| Standards status: Informative | Computable Name: Cardiovascular_mortality_from_MAGICapp_313877 | ||||
| Other Identifiers: FEvIR Object Identifier: FEvIR Object Identifier#557022, outcomeId: 313877, picoId: 85789, sectionId: 73212, OID:2.16.840.1.113883.4.642.40.44.22.151 | |||||
Usage: Evidence Communication: ComparativeEvidence |
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Copyright/Legal: Copyright the Authors else Computable Publishing LLC. Noncommercial use permitted with CC BY-NC-SA 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/). Commercial use permitted as agreed in Terms of Use (https://fevir.net/termsofuse). |
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This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.
version: 3; Last updated: 2026-08-29 20:43:48+0000
Profile: ComparativeEvidence
ArtifactPublicationStatus: Active
identifier: FEvIR Object Identifier/557022, outcomeId/313877, picoId/85789, sectionId/73212, Uniform Resource Identifier (URI)/urn:oid:2.16.840.1.113883.4.642.40.44.22.151
version: 1.0.0-ballot3
name: Cardiovascular_mortality_from_MAGICapp_313877
title: MAGIC-derived Evidence: Cardiovascular mortality with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
citeAs:
MAGIC-derived Evidence: Cardiovascular mortality with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk [Database Entry: FHIR Evidence Resource]. Contributors: Computable Publishing®: MAGIC-to-FEvIR Converter [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 557022. Revised 2026-08-29. Available at: https://fevir.net/resources/Evidence/557022. Computable resource at: https://fevir.net/resources/Evidence/557022#json.
status: Active
date: 2026-11-05 14:34:28+0000
author: Computable Publishing®: MAGIC-to-FEvIR Converter:
publisher: HL7 International / Clinical Decision Support
contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss
| Code | Value[x] |
| Evidence Based Medicine on FHIR Implementation Guide Code System: evidence-communication (Evidence Communication) | ComparativeEvidence |
copyright:
Copyright the Authors else Computable Publishing LLC. Noncommercial use permitted with CC BY-NC-SA 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/). Commercial use permitted as agreed in Terms of Use (https://fevir.net/termsofuse).
| Type | Target[x] |
| Part Of | MAGICapp Conversion Report: SGLT2 inhibitors and GLP-1 RA for type 2 diabetes (Identifier: FEvIR Linking Identifier/MAGIC-5288-j1Wqrn-conversion-report) |
description:
This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.
assertion:
GLP-1 receptor agonists probably reduce the risk of cardiovascular death compared with standard care.
variableDefinition
description:
Adults with type 2 diabetes with moderate CV risk
variableRole: Population
observed: Adults with type 2 diabetes and established CVD (but no CKD)
variableDefinition
description:
GroupAssignment: GLP-1 RA vs. Standard care
variableRole: Exposure
comparatorCategory: Standard care
variableDefinition
description:
Cardiovascular mortality
variableRole: Outcome
observed: Cardiovascular mortality
synthesisType: SYSTEMATIC_REVIEW
studyDesign: randomized assignment
statistic
description:
Risk Difference -0.9% (CI95 -1.5% to -0.3%)
statisticType: risk difference
quantity: -0.009
SampleSizes
NumberOfStudies NumberOfParticipants 20 63455 AttributeEstimates
Type Range CI95 -0.015--0.003
statistic
description:
OR 0.88 (CI95 0.8 to 0.96)
statisticType: odds ratio
quantity: 0.88
SampleSizes
NumberOfStudies NumberOfParticipants 20 63455 AttributeEstimates
Type Range CI95 0.8-0.96
certainty
description:
Due to serious imprecision
type: Overall certainty
rating: Moderate certainty
Subcomponents
Type Rating Risk of Bias NOTSET Inconsistency NOTSET Indirectness NOTSET Imprecision NOTSET Publication Bias NOTSET