Evidence Based Medicine on FHIR Implementation Guide
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Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan - XML Representation

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<Evidence xmlns="http://hl7.org/fhir">
  <id value="397481"/>
  <meta>
    <versionId value="6"/>
    <lastUpdated value="2025-09-13T18:19:34.404Z"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p><b>Title: </b>Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan</p><p><b>Variable in role of population: </b>the study group</p><p><b>Variable in role of exposure: </b>GroupAssignment: Quadpill vs. Candesartan</p><p><b>Variable in role of outcome: </b>Medication Adherence at 12 weeks</p><p><b>Statistic: </b>odds ratio (coded as: STATO:0000182 from https://fevir.net/sevco) 0.37</p></div>
  </text>
  <url value="https://fevir.net/resources/Evidence/397481"/>
  <identifier>
    <type>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
        <code value="ACSN"/>
        <display value="Accession ID"/>
      </coding>
      <text value="FEvIR Object Identifier"/>
    </type>
    <system value="https://fevir.net/FOI"/>
    <value value="397481"/>
    <assigner>
      <display value="Computable Publishing LLC"/>
    </assigner>
  </identifier>
  <name
        value="Evidence_for_Results_for_Medication_Adherence_at_12_weeks_in_GroupAssignment_Quadpill_vs_Candesartan"/>
  <title
         value="Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
  <citeAs
          value="Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan [Database Entry: FHIR Evidence Resource]. Contributors: Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 397481. Revised 2025-09-13. Available at: https://fevir.net/resources/Evidence/397481. Computable resource at: https://fevir.net/resources/Evidence/397481#json."/>
  <status value="active"/>
  <author>
    <name value="Brian S. Alper, MD, MSPH"/>
  </author>
  <publisher value="Computable Publishing LLC"/>
  <contact>
    <telecom>
      <system value="email"/>
      <value value="support@computablepublishing.com"/>
    </telecom>
  </contact>
  <copyright value="https://creativecommons.org/licenses/by-nc-sa/4.0/"/>
  <relatesTo>
    <type value="part-of"/>
    <targetReference>🔗 
      <reference value="Composition/375280"/>
      <type value="Composition"/>
      <display value="Outcome Measure Report for QUARTET USA Trial"/>
    </targetReference>
  </relatesTo>
  <description
               value="This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide."/>
  <variableDefinition>
    <variableRole value="population"/>
    <observed>
      <display value="the study group"/>
    </observed>
  </variableDefinition>
  <variableDefinition>
    <variableRole value="exposure"/>
    <observed>🔗 
      <reference value="EvidenceVariable/375183"/>
      <type value="EvidenceVariable"/>
      <display value="GroupAssignment: Quadpill vs. Candesartan"/>
    </observed>
  </variableDefinition>
  <variableDefinition>
    <variableRole value="outcome"/>
    <observed>🔗 
      <reference value="EvidenceVariable/375201"/>
      <type value="EvidenceVariable"/>
      <display value="Medication Adherence at 12 weeks"/>
    </observed>
  </variableDefinition>
  <statistic>
    <statisticType>
      <coding>
        <system value="https://fevir.net/sevco"/>
        <code value="STATO:0000182"/>
        <display value="odds ratio"/>
      </coding>
    </statisticType>
    <quantity>
      <value value="0.37"/>
    </quantity>
    <sampleSize>
      <numberOfParticipants value="62"/>
      <knownDataCount value="53"/>
    </sampleSize>
    <attributeEstimate>
      <type>
        <coding>
          <system value="https://fevir.net/sevco"/>
          <code value="STATO:0000196"/>
          <display value="confidence interval"/>
        </coding>
      </type>
      <level value="0.95"/>
      <range>
        <low>
          <value value="0.19"/>
        </low>
        <high>
          <value value="2.08"/>
        </high>
      </range>
    </attributeEstimate>
    <attributeEstimate>
      <type>
        <coding>
          <system value="https://fevir.net/sevco"/>
          <code value="STATO:0000700"/>
          <display value="p-value"/>
        </coding>
      </type>
      <quantity>
        <value value="0.444"/>
      </quantity>
    </attributeEstimate>
  </statistic>
</Evidence>