Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot2 - STU 1 ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan - JSON Representation

Raw json | Download

{
  "resourceType" : "Evidence",
  "id" : "397481",
  "meta" : {
    "versionId" : "6",
    "lastUpdated" : "2025-09-13T18:19:34.404Z"
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Title: </b>Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan</p><p><b>Variable in role of population: </b>the study group</p><p><b>Variable in role of exposure: </b>GroupAssignment: Quadpill vs. Candesartan</p><p><b>Variable in role of outcome: </b>Medication Adherence at 12 weeks</p><p><b>Statistic: </b>odds ratio (coded as: STATO:0000182 from https://fevir.net/sevco) 0.37</p></div>"
  },
  "url" : "https://fevir.net/resources/Evidence/397481",
  "identifier" : [
    {
      "type" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "ACSN",
            "display" : "Accession ID"
          }
        ],
        "text" : "FEvIR Object Identifier"
      },
      "system" : "https://fevir.net/FOI",
      "value" : "397481",
      "assigner" : {
        "display" : "Computable Publishing LLC"
      }
    }
  ],
  "name" : "Evidence_for_Results_for_Medication_Adherence_at_12_weeks_in_GroupAssignment_Quadpill_vs_Candesartan",
  "title" : "Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan",
  "citeAs" : "Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan [Database Entry: FHIR Evidence Resource]. Contributors: Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 397481. Revised 2025-09-13. Available at: https://fevir.net/resources/Evidence/397481. Computable resource at: https://fevir.net/resources/Evidence/397481#json.",
  "status" : "active",
  "author" : [
    {
      "name" : "Brian S. Alper, MD, MSPH"
    }
  ],
  "publisher" : "Computable Publishing LLC",
  "contact" : [
    {
      "telecom" : [
        {
          "system" : "email",
          "value" : "support@computablepublishing.com"
        }
      ]
    }
  ],
  "copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "relatesTo" : [
    {
      "type" : "part-of",
      "targetReference" : {
        🔗 "reference" : "Composition/375280",
        "type" : "Composition",
        "display" : "Outcome Measure Report for QUARTET USA Trial"
      }
    }
  ],
  "description" : "This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.",
  "variableDefinition" : [
    {
      "variableRole" : "population",
      "observed" : {
        "display" : "the study group"
      }
    },
    {
      "variableRole" : "exposure",
      "observed" : {
        🔗 "reference" : "EvidenceVariable/375183",
        "type" : "EvidenceVariable",
        "display" : "GroupAssignment: Quadpill vs. Candesartan"
      }
    },
    {
      "variableRole" : "outcome",
      "observed" : {
        🔗 "reference" : "EvidenceVariable/375201",
        "type" : "EvidenceVariable",
        "display" : "Medication Adherence at 12 weeks"
      }
    }
  ],
  "statistic" : [
    {
      "statisticType" : {
        "coding" : [
          {
            "system" : "https://fevir.net/sevco",
            "code" : "STATO:0000182",
            "display" : "odds ratio"
          }
        ]
      },
      "quantity" : {
        "value" : 0.37
      },
      "sampleSize" : {
        "numberOfParticipants" : 62,
        "knownDataCount" : 53
      },
      "attributeEstimate" : [
        {
          "type" : {
            "coding" : [
              {
                "system" : "https://fevir.net/sevco",
                "code" : "STATO:0000196",
                "display" : "confidence interval"
              }
            ]
          },
          "level" : 0.95,
          "range" : {
            "low" : {
              "value" : 0.19
            },
            "high" : {
              "value" : 2.08
            }
          }
        },
        {
          "type" : {
            "coding" : [
              {
                "system" : "https://fevir.net/sevco",
                "code" : "STATO:0000700",
                "display" : "p-value"
              }
            ]
          },
          "quantity" : {
            "value" : 0.444
          }
        }
      ]
    }
  ]
}