Evidence Based Medicine on FHIR Implementation Guide
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Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: Evidence for Results for Systolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Evidence ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "375907"] ; # 
  fhir:meta [
fhir:versionId [ fhir:v "11" ] ;
fhir:lastUpdated [ fhir:v "2025-08-15T10:17:51.868Z"^^xsd:dateTime ] ;
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/comparative-evidence"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/uv/ebm/StructureDefinition/comparative-evidence>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"^^rdf:XMLLiteral
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "active" ] ;
fhir:display [ fhir:v "Active" ]       ] )     ]
  ] ) ; # 
  fhir:url [ fhir:v "https://fevir.net/resources/Evidence/375907"^^xsd:anyURI] ; # 
  fhir:identifier ( [
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ACSN" ] ;
fhir:display [ fhir:v "Accession ID" ]       ] ) ;
fhir:text [ fhir:v "FEvIR Object Identifier" ]     ] ;
fhir:system [ fhir:v "https://fevir.net/FOI"^^xsd:anyURI ] ;
fhir:value [ fhir:v "375907" ] ;
fhir:assigner [
fhir:display [ fhir:v "Computable Publishing LLC" ]     ]
  ] ) ; # 
  fhir:name [ fhir:v "Evidence_for_Results_for_Systolic_blood_pressure_at_12_weeks_in_GroupAssignment_Quadpill_vs_Candesartan"] ; # 
  fhir:title [ fhir:v "Evidence for Results for Systolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"] ; # 
  fhir:citeAs [ fhir:v "Evidence for Results for Systolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan [Database Entry: FHIR Evidence Resource]. Contributors: Joanne Dehnbostel [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 375907. Revised 2025-08-15. Available at: https://fevir.net/resources/Evidence/375907. Computable resource at: https://fevir.net/resources/Evidence/375907#json."] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:author ( [
fhir:name [ fhir:v "Joanne Dehnbostel" ]
  ] ) ; # 
  fhir:publisher [ fhir:v "Computable Publishing LLC"] ; # 
  fhir:contact ( [
    ( fhir:telecom [
fhir:system [ fhir:v "email" ] ;
fhir:value [ fhir:v "support@computablepublishing.com" ]     ] )
  ] ) ; # 
  fhir:copyright [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/"] ; # 
  fhir:relatesTo ( [
fhir:type [ fhir:v "part-of" ] ;
fhir:target [
a fhir:Reference ;
fhir:reference [ fhir:v "Composition/375280" ] ;
fhir:type [ fhir:v "Composition"^^xsd:anyURI ] ;
fhir:display [ fhir:v "Outcome Measure Report for QUARTET USA Trial" ]     ]
  ] ) ; # 
  fhir:description [ fhir:v "This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide."] ; # 
  fhir:variableDefinition ( [
fhir:variableRole [ fhir:v "exposure" ] ;
fhir:comparatorCategory [ fhir:v "Candesartan 8 mg once daily" ] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/375183" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "GroupAssignment: Quadpill vs. Candesartan" ]     ]
  ] [
fhir:variableRole [ fhir:v "outcome" ] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/375185" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "Systolic blood pressure at 12 weeks" ]     ]
  ] [
fhir:variableRole [ fhir:v "population" ] ;
fhir:observed [
fhir:reference [ fhir:v "Group/372797" ] ;
fhir:type [ fhir:v "Group"^^xsd:anyURI ] ;
fhir:display [ fhir:v "Enrolled Group for QUARTET USA Trial (372797)" ]     ]
  ] ) ; # 
  fhir:statistic ( [
fhir:statisticType [
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/sevco"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000457" ] ;
fhir:display [ fhir:v "difference in means" ]       ] )     ] ;
fhir:quantity [
fhir:value [ fhir:v -4.5 ] ;
fhir:unit [ fhir:v "mm Hg" ]     ] ;
fhir:sampleSize [
      ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/number-analyzed"^^xsd:anyURI ] ;
fhir:value [
a fhir:unsignedInt ;
fhir:v "60"^^xsd:nonNegativeInteger         ]       ] ) ;
fhir:numberOfParticipants [ fhir:v "62"^^xsd:nonNegativeInteger ] ;
fhir:knownDataCount [ fhir:v "53"^^xsd:nonNegativeInteger ]     ] ;
    ( fhir:attributeEstimate [
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/sevco"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000196" ] ;
fhir:display [ fhir:v "confidence interval" ]         ] )       ] ;
fhir:level [ fhir:v 0.95 ] ;
fhir:range [
fhir:low [
fhir:value [ fhir:v -10.82 ] ;
fhir:unit [ fhir:v "mm Hg" ]         ] ;
fhir:high [
fhir:value [ fhir:v 1.32 ] ;
fhir:unit [ fhir:v "mm Hg" ]         ]       ]     ] [
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/sevco"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000700" ] ;
fhir:display [ fhir:v "p-value" ]         ] )       ] ;
fhir:quantity [
fhir:value [ fhir:v 0.123 ]       ]     ] )
  ] ) . #