Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
{
"resourceType" : "Evidence",
"id" : "179588",
"meta" : {
"versionId" : "6",
"lastUpdated" : "2023-12-08T13:32:26.958Z",
"profile" : [
🔗 "http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Evidence 179588</b></p><a name=\"179588\"> </a><a name=\"hc179588\"> </a><a name=\"179588-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 6; Last updated: 2023-12-08 13:32:26+0000</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-net-effect-contribution.html\">NetEffectContribution</a></p></div><p><b>url</b>: <a href=\"https://fevir.net/resources/Evidence/179588\">https://fevir.net/resources/Evidence/179588</a></p><p><b>identifier</b>: FEvIR Object Identifier/179588</p><p><b>name</b>: NetEffectContribution_Remission_of_diabetes_for_Example_for_GIN_2022</p><p><b>title</b>: NetEffectContribution: Remission of diabetes for Example for GIN 2022</p><p><b>status</b>: Active</p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href=\"mailto:support@computablepublishing.com\">support@computablepublishing.com</a></p><p><b>author</b>: Brian S. Alper: </p><h3>UseContexts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"CodeSystem-179423.html#179423-evidence-communication\">Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication</a>: Evidence Communication</td><td><span title=\"Codes:{https://fevir.net/resources/CodeSystem/179423 ComparativeEvidence}\">ComparativeEvidence</span></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"CodeSystem-179423.html#179423-evidence-communication\">Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication</a>: Evidence Communication</td><td><span title=\"Codes:{https://fevir.net/resources/CodeSystem/179423 NetEffectContribution}\">NetEffectContribution</span></td></tr></table><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Citation</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>Cite As</td><td><div><p>NetEffectContribution: Remission of diabetes for Example for GIN 2022 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179588. Revised 2023-12-06. Available at: https://fevir.net/resources/Evidence/179588. Computable resource at: https://fevir.net/resources/Evidence/179588.</p>\n</div></td><td> </td></tr><tr><td style=\"display: none\">*</td><td>Amended With</td><td> </td><td><a href=\"ArtifactAssessment-104193.html\">Outcome Importance Rating (default value 5) of Remission of diabetes</a></td></tr></table><p><b>description</b>: </p><div><p>2.15 (1.33 to 3.26) - example showing statistic.extension:modelExpression</p>\n</div><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n\u2009=\u20092109) with severe obesity assessed (221 patients excluded and 1888 patients included).</p>\n</div><p><b>variableRole</b>: Population</p><p><b>observed</b>: <a href=\"Group-178427.html\">StudyGroup: Severely Obese Adults 2018 Norwegian Cohort</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>comparison groups of bariatric surgery vs. no bariatric surgery</p>\n</div><p><b>variableRole</b>: Exposure</p><p><b>comparatorCategory</b>: no bariatric surgery</p><p><b>observed</b>: <a href=\"EvidenceVariable-172427.html\">GroupAssignment: Bariatric Surgery vs. no bariatric surgery</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>Remission of diabetes</p>\n</div><p><b>variableRole</b>: Outcome</p><p><b>observed</b>: <a href=\"EvidenceVariable-104117.html\">OutcomeVariable: Remission of diabetes</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>Relative Importance Multiplier</p>\n</div><p><b>variableRole</b>: Covariate</p><p><b>roleSubtype</b>: <span title=\"Codes:{https://fevir.net/resources/CodeSystem/179423 importance-multiplier}\">Relative importance multiplier</span></p><p><b>observed</b>: Relative Importance Multiplier</p></blockquote><blockquote><p><b>statistic</b></p><p><b>StatisticModelExpression</b>: <code>Evidence[id='104121'].statistic[statisticType='Relative Risk'] * Evidence[id='104396'].statistic[statisticType='Proportion'] * $this.relatedArtifact[type=#amended-with].resourceReference(processOutcomeImportance)</code>(<b>Net effect contribution analysis</b>"risk difference (relative risk x control event rate) multiplied by relative importance multiplier (defined in OutcomeImportance Profile) -- expression is pseudocode to demonstrate the concept")</p><p><b>description</b>: </p><div><p>risk difference 2.15 (95% CI 1.33 to 3.26)</p>\n</div><p><b>statisticType</b>: <span title=\"Codes:{https://fevir.net/resources/CodeSystem/181513 STATO:0000424}\">Risk Difference</span></p><p><b>quantity</b>: 2.15</p><h3>AttributeEstimates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Description</b></td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td><div><p>95% CI 1.33 to 3.26</p>\n</div></td><td><span title=\"Codes:{https://fevir.net/resources/CodeSystem/181513 STATO:0000196}\">confidence interval</span></td><td>0.95</td><td>1.33-3.26</td></tr></table><h3>ModelCharacteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{https://fevir.net/resources/CodeSystem/181513 TBD:net-effect-contribution-analysis}\">Net effect contribution analysis</span></td></tr></table></blockquote></div>"
},
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"identifier" : [
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"text" : "FEvIR Object Identifier"
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"system" : "https://fevir.net",
"value" : "179588",
"assigner" : {
"display" : "Computable Publishing LLC"
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"name" : "NetEffectContribution_Remission_of_diabetes_for_Example_for_GIN_2022",
"title" : "NetEffectContribution: Remission of diabetes for Example for GIN 2022",
"status" : "active",
"publisher" : "Computable Publishing LLC",
"contact" : [
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"author" : [
{
"name" : "Brian S. Alper"
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"useContext" : [
{
"code" : {
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "evidence-communication",
"display" : "Evidence Communication"
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"valueCodeableConcept" : {
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"code" : "ComparativeEvidence",
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{
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"code" : "evidence-communication",
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{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "NetEffectContribution",
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],
"copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/",
"relatedArtifact" : [
{
"type" : "cite-as",
"citation" : "NetEffectContribution: Remission of diabetes for Example for GIN 2022 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179588. Revised 2023-12-06. Available at: https://fevir.net/resources/Evidence/179588. Computable resource at: https://fevir.net/resources/Evidence/179588."
},
{
"type" : "amended-with",
"resourceReference" : {
🔗 "reference" : "ArtifactAssessment/104193",
"type" : "ArtifactAssessment",
"display" : "Outcome Importance Rating (default value 5) of Remission of diabetes"
}
}
],
"description" : "2.15 (1.33 to 3.26) - example showing statistic.extension:modelExpression",
"variableDefinition" : [
{
"description" : "Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n\u2009=\u20092109) with severe obesity assessed (221 patients excluded and 1888 patients included).",
"variableRole" : "population",
"observed" : {
🔗 "reference" : "Group/178427",
"type" : "Group",
"display" : "StudyGroup: Severely Obese Adults 2018 Norwegian Cohort"
}
},
{
"description" : "comparison groups of bariatric surgery vs. no bariatric surgery",
"variableRole" : "exposure",
"comparatorCategory" : "no bariatric surgery",
"observed" : {
🔗 "reference" : "EvidenceVariable/172427",
"type" : "EvidenceVariable",
"display" : "GroupAssignment: Bariatric Surgery vs. no bariatric surgery"
}
},
{
"description" : "Remission of diabetes",
"variableRole" : "outcome",
"observed" : {
🔗 "reference" : "EvidenceVariable/104117",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Remission of diabetes"
}
},
{
"description" : "Relative Importance Multiplier",
"variableRole" : "covariate",
"roleSubtype" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "importance-multiplier",
"display" : "Relative importance multiplier"
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"observed" : {
"display" : "Relative Importance Multiplier"
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}
],
"statistic" : [
{
"extension" : [
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"url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/statistic-model-expression",
"valueExpression" : {
"description" : "risk difference (relative risk x control event rate) multiplied by relative importance multiplier (defined in OutcomeImportance Profile) -- expression is pseudocode to demonstrate the concept",
"name" : "Net effect contribution analysis",
"expression" : "Evidence[id='104121'].statistic[statisticType='Relative Risk'] * Evidence[id='104396'].statistic[statisticType='Proportion'] * $this.relatedArtifact[type=#amended-with].resourceReference(processOutcomeImportance)"
}
}
],
"description" : "risk difference 2.15 (95% CI 1.33 to 3.26)",
"statisticType" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/181513",
"code" : "STATO:0000424",
"display" : "Risk Difference"
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]
},
"quantity" : {
"value" : 2.15
},
"attributeEstimate" : [
{
"description" : "95% CI 1.33 to 3.26",
"type" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/181513",
"code" : "STATO:0000196",
"display" : "confidence interval"
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"level" : 0.95,
"range" : {
"low" : {
"value" : 1.33
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"high" : {
"value" : 3.26
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],
"modelCharacteristic" : [
{
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/181513",
"code" : "TBD:net-effect-contribution-analysis",
"display" : "Net effect contribution analysis"
}
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}
]
}
]
}
IG © 2024+ HL7 International / Clinical Decision Support. Package hl7.fhir.uv.ebm#2.0.0-ballot based on FHIR 6.0.0-ballot2. Generated 2024-11-21
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