Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
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"lastUpdated" : "2024-12-12T13:06:16.440Z",
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🔗 "http://hl7.org/fhir/uv/ebm/StructureDefinition/certainty-of-evidence"
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"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ArtifactAssessment 179693</b></p><a name=\"179693\"> </a><a name=\"hc179693\"> </a><a name=\"179693-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 7; Last updated: 2024-12-12 13:06:16+0000</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-certainty-of-evidence.html\">CertaintyOfEvidence</a></p></div><p><b>Artifact URL</b>: <a href=\"https://fevir.net/resources/ArtifactAssessment/179693\">https://fevir.net/resources/ArtifactAssessment/179693</a></p><p><b>Artifact Description</b>: </p><div><p>This example of a CertaintyOfEvidence Profile shows a recursive pattern of component elements with type/classifier paired values for different aspects of rating the certainty of evidence.</p>\n</div><p><b>identifier</b>: FEvIR Object Identifier/https://fevir.net/FOI/179693</p><p><b>title</b>: Certainty of Evidence Rating of 14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY)</p><p><b>artifact</b>: <a href=\"Evidence-55.html\">14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY)</a></p><blockquote><p><b>content</b></p><p><b>summary</b>: </p><div><p>Low certainty due to inconsistency and risk of bias</p>\n</div><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Overall}\">Overall certainty</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating low}\">Low quality</span></p><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type PublicationBias}\">Publication bias</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote><blockquote><p><b>component</b></p><p><b>summary</b>: </p><div><p>There is a high degree of heterogeneity (I-squared = 73%). There is also inconsistency in findings between the fixed-effect and random-effects statistical models.</p>\n</div><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Inconsistency}\">Inconsistency</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating serious-concern}\">serious concern</span></p></blockquote><blockquote><p><b>component</b></p><p><b>summary</b>: </p><div><p>Although the random-effects analysis finds an estimate without statistical significance, this imprecision is explained by the inconsistency (heterogeneity) and thus not further downrated in certainty assessment.</p>\n</div><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Imprecision}\">Imprecision</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Indirectness}\">Indirectness</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type RiskOfBias}\">Risk of bias</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating serious-concern}\">serious concern</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Summary</b></td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><div><p>No blinding (no placebo control) in the largest trial</p>\n</div></td><td><span title=\"Codes:{https://fevir.net/resources/CodeSystem/181513 SEVCO:00035}\">Lack of blinding</span></td><td><span title=\"Codes:{http://hl7.org/fhir/certainty-rating present}\">present</span></td></tr></table></blockquote></blockquote></div>"
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"valueMarkdown" : "This example of a CertaintyOfEvidence Profile shows a recursive pattern of component elements with type/classifier paired values for different aspects of rating the certainty of evidence."
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"title" : "Certainty of Evidence Rating of 14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY)",
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🔗 "reference" : "Evidence/55",
"type" : "Evidence",
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"summary" : "Low certainty due to inconsistency and risk of bias",
"type" : {
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"system" : "http://hl7.org/fhir/certainty-type",
"code" : "Inconsistency",
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IG © 2024+ HL7 International / Clinical Decision Support. Package hl7.fhir.uv.ebm#2.0.0-ballot based on FHIR 6.0.0-ballot2. Generated 2024-12-19
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