This is the Continuous Integration Build of FHIR (will be incorrect/inconsistent at times).
See the Directory of published versions
Biomedical Research and Regulation Work Group | Maturity Level: N/A | Standards Status: Informative | Compartments: No defined compartments |
Raw XML (canonical form + also see XML Format Specification)
Example of substancesourcematerial (id = "example")
<?xml version="1.0" encoding="UTF-8"?> <!-- numberOfMoieties value="2"/> <identifier> <system value="http://substanceidOID"/> <value value="POYFG4531Y (Artificial ID)"/> </identifier> <substanceType> <coding> <system value="http://substancetypeOID"/> <code value="Chemical"/> </coding> </substanceType> <moiety> <moietyRole> <coding> <system value="http://moietyroleOID"/> <code value="SaltMolecule"/> </coding> </moietyRole> <moietyId> <system value="http://moietyidOID"/> <value value="HJFGTE8954 (Artificial ID); [QTT17582CB (UNII)]"/> </moietyId> <moietyName value="Hydrochloric acid"/> <stereochemistry> <coding> <system value="http://stereochemistryOID"/> <code value="Achiral"/> </coding> </stereochemistry> <opticalActivity> <coding> <system value="http://opticalactivityOID"/> <code value="N/A"/> </coding> </opticalActivity> <molecularFormula value="HCl"/> <amount> <amountType> <coding> <system value="http://amounttypeOID"/> <code value="MoleRatiotoParent"/> </coding> </amountType> <average> <value value="1"/> <unit value="1"/> </average> <nonNumericValue value="Mole Ratio to Ponatinib"/> </amount> </moiety> <moiety> <moietyRole> <coding> <system value="http://moietyroleOID"/> <code value="Parentsubstance"/> </coding> </moietyRole> <moietyId> <system value="http://moietyidOID"/> <value value="PONG785632B (Artificial ID); [QTT17582CB (UNII)]"/> </moietyId> <moietyName value="Ponatinib"/> <stereochemistry> <coding> <system value="http://stereochemistryOID"/> <code value="Achiral"/> </coding> </stereochemistry> <opticalActivity> <coding> <system value="http://opticalactivityOID"/> <code value="N/A"/> </coding> </opticalActivity> <molecularFormula value="C29H27F3N6O"/> <amount> <amountType> <coding> <system value="http://amounttypeOID"/> <code value="MoleRatiotoAcid"/> </coding> </amountType> <average> <value value="1"/> <unit value="1"/> </average> <nonNumericValue value="Mol Ratio Ponatinib/ Ponatinib hydrochloride (1:1)"/> </amount> </moiety> <referenceInformation> <substanceClassification> <domain> <coding> <system value="http://domainOID"/> <code value="HumanPharmaceutical"/> </coding> </domain> <substanceClassificationCode value="L01XE24"/> <substanceClassificationType value="Ponatinib"/> <referenceSource> <publicDomain value="true"/> <referenceSourceType> <coding> <system value="http://referencesourcetypeOID"/> <code value="WHOCollaboratingCentreforDrugStatisticsmethodology(WHOCC)"/> </coding> </referenceSourceType> <referenceSourceClass> <coding> <system value="http://referencesourceclassOID"/> <code value="Web"/> </coding> </referenceSourceClass> <referenceSourceCitation value="http://www.whocc.no/atc_ddd_index/?code=L01XE24 "/> </referenceSource> </substanceClassification> <substanceRelationship> <relatedSubstanceId> <system value="http://relatedsubstanceidOID"/> <value value="GHF26754YQ (Artificial ID), [4340891KFS (UNII)]"/> </relatedSubstanceId> <relatedSubstanceName value="Ponatinib"/> <relationship> <coding> <system value="http://relationshipOID"/> <code value="Parentsubstancetosalt"/> </coding> </relationship> <relationshipType> <coding> <system value="http://relationshiptypeOID"/> <code value="Ionic"/> </coding> </relationshipType> <isDefining value="true"/> <amount> <amountType> <coding> <system value="http://amounttypeOID"/> <code value="Weightpercenttosalt"/> </coding> </amountType> <average> <value value="93.6"/> <unit value="1"/> </average> <unit> <coding> <system value="http://unitOID"/> <code value="Weightpercent"/> </coding> </unit> <nonNumericValue value="Equivalent factor: 0.936"/> </amount> </substanceRelationship> </referenceInformation> <referenceSource> <publicDomain value="false"/> <referenceSourceType> <coding> <system value="http://referencesourcetypeOID"/> <code value="MarketingAuthorizationApplication"/> </coding> </referenceSourceType> <referenceSourceClass> <coding> <system value="http://referencesourceclassOID"/> <code value="Regulatorysubmission"/> </coding> </referenceSourceClass> <referenceSourceId value="33333 (Artificial ID)"/> <referenceSourceDocument> <document> <contentType value="text/plain"/> <data value="U3lteXggICAwNjA5MTQyMjExMkQgMSAgIDEuMDAwMDAgICAgIDAuMDAwMDAgICAgIDAg XG4gNDAgNDMgIDAgICAgIDAgIDAgICAgICAgICAgICA5OTkgVjIwMDBcbiAgIC0yLjIzNDAgICAtMC4xNjYxICAgIDAuMD AwMCBOICAgMCAgMCAgMCAgMCAgMCAgMCAgICAgICAgICAgMCAgMCAgMA=="/> </document> <referenceSourceDocumentType> <coding> <system value="http://referencesourcedocumenttypeOID"/> <code value="Textfile"/> </coding> </referenceSourceDocumentType> </referenceSourceDocument> </referenceSource> <structure> <stereochemistry> <coding> <system value="http://stereochemistryOID"/> <code value="Achiral"/> </coding> </stereochemistry> <opticalActivity> <coding> <system value="http://opticalactivityOID"/> <code value="N/A"/> </coding> </opticalActivity> <molecularFormula value="C29H28F3ClN6O"/> <molecularFormulaByMoiety value="C29H27F3N6O.HCl"/> <molecularWeight> <molecularWeightMethod> <coding> <system value="http://molecularweightmethodOID"/> <code value="Calculated"/> </coding> </molecularWeightMethod> <molecularWeightType> <coding> <system value="http://molecularweighttypeOID"/> <code value="Numberaverage"/> </coding> </molecularWeightType> <amount> <amountType> <coding> <system value="http://amounttypeOID"/> <code value="Exact"/> </coding> </amountType> <average> <value value="569.02"/> <unit value="1"/> </average> <unit> <coding> <system value="http://unitOID"/> <code value="g/mol"/> </coding> </unit> </amount> </molecularWeight> <referenceSource> <publicDomain value="true"/> <referenceSourceType> <coding> <system value="http://referencesourcetypeOID"/> <code value="ChemIDplus"/> </coding> </referenceSourceType> <referenceSourceClass> <coding> <system value="http://referencesourceclassOID"/> <code value="PublicDatabase"/> </coding> </referenceSourceClass> <referenceSourceCitation value="http://chem.sis.nlm.nih.gov/chemidplus/unii/96R6PU3D 8J "/> </referenceSource> <structuralRepresentation> <type> <coding> <system value="http://structuralrepresentationtypeOID"/> <code value="Full"/> </coding> </type> <representation value="Figure B.40"/> </structuralRepresentation> <structuralRepresentation> <type> <coding> <system value="http://structuralrepresentationtypeOID"/> <code value="InChI"/> </coding> </type> <representation value="InChI=1S/C29H27F3N6O.ClH/c1-20-5-6-22(16-21(20)8-10-25-18-33- 27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37;/h3-7, 9,11,16-18H,12-15,19H2,1-2H3,(H,35,39);1H"/> </structuralRepresentation> <structuralRepresentation> <type> <coding> <system value="http://structuralrepresentationtypeOID"/> <code value="SMILES"/> </coding> </type> <representation value="Cc1ccc(cc1C#Cc2cnc3n2nccc3)C(=O)Nc4ccc(c(c4)C(F)(F)F)CN5CCN(C C5)C.Cl"/> </structuralRepresentation> <structuralRepresentation> <type> <coding> <system value="http://structuralrepresentationtypeOID"/> <code value="MOL"/> </coding> </type> <attachment> <contentType value="text/plain"/> <data value="U3lteXggICAwNjA5MTQyMjExMkQgMSAgIDEuMDAwMDAgICAgIDAuMDAwMDAgICAgIDAg XG4gNDAgNDMgIDAgICAgIDAgIDAgICAgICAgICAgICA5OTkgVjIwMDBcbiAgIC0yLjIzNDAgICAtMC4xNjYxICAgIDAuMD AwMCBOICAgMCAgMCAgMCAgMCAgMCAgMCAgICAgICAgICAgMCAgMCAgMA=="/> </attachment> </structuralRepresentation> </structure> <substanceCode> <code value="1114544-31-8"/> <codeSystemStatus> <coding> <system value="http://1.1.149"/> <code value="Active"/> </coding> </codeSystemStatus> </substanceCode> <substanceCode> <code value="96R6PU3D8J"/> <codeSystemStatus> <coding> <system value="http://1.1.150"/> <code value="Active"/> </coding> </codeSystemStatus> </substanceCode> <substanceName> <substanceName value="Ponatinib hydrochloride"/> <substanceNameType> <coding> <system value="http://substancenametypeOID"/> <code value="Official"/> </coding> </substanceNameType> <language> <coding> <system value="http://languageOID"/> <code value="en"/> </coding> </language> <substanceNameDomain> <coding> <system value="http://substancenamedomainOID"/> <code value="Drug"/> </coding> </substanceNameDomain> <jurisdiction> <coding> <system value="http://jurisdictionOID"/> <code value="EU,US"/> </coding> </jurisdiction> <officialName> <officialNameType> <coding> <system value="http://officialnametypeOID"/> <code value="USAN"/> </coding> </officialNameType> <officialNameStatus> <coding> <system value="http://officialnamestatusOID"/> <code value="Current"/> </coding> </officialNameStatus> </officialName> <referenceSource> <publicDomain value="true"/> <referenceSourceType> <coding> <system value="http://referencesourcetypeOID"/> <code value="Martindale"/> </coding> </referenceSourceType> <referenceSourceClass> <coding> <system value="http://referencesourceclassOID"/> <code value="Officialnamesource"/> </coding> </referenceSourceClass> <referenceSourceCitation value="Martindale The complete drug reference"/> <referenceSourceUrl value="https://www.medicinescomplete.com/mc/martindale/current/m s-28485-s.htm?q=Ponatinib%20hydrochloride&t=search&ss=text&tot=12&p=1#_hit"/> <referenceSourceDocument> <publicDomain value="true"/> <referenceSourceDocumentType> <coding> <system value="http://referencesourcedocumenttypeOID"/> <code value="Journalarticle"/> </coding> </referenceSourceDocumentType> </referenceSourceDocument> </referenceSource> </substanceName> <substanceName> <substanceName value="3-(2-(Imidazo(1,2-b)pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-met hylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide monohydrochloride"/> <substanceNameType> <coding> <system value="http://substancenametypeOID"/> <code value="Systematic"/> </coding> </substanceNameType> <language> <coding> <system value="http://languageOID"/> <code value="en"/> </coding> </language> <referenceSource> <publicDomain value="true"/> <referenceSourceType> <coding> <system value="http://referencesourcetypeOID"/> <code value="ChemIDplus"/> </coding> </referenceSourceType> <referenceSourceClass> <coding> <system value="http://referencesourceclassOID"/> <code value="PublicDatabase"/> </coding> </referenceSourceClass> <referenceSourceCitation value="http://chem.sis.nlm.nih.gov/chemidplus/unii/96R6PU3D 8J "/> </referenceSource> </substanceName> <substanceName> <substanceName value="Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[ 4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-,hydrochloride (1:1)"/> <substanceNameType> <coding> <system value="http://substancenametypeOID"/> <code value="OtherName"/> </coding> </substanceNameType> <language> <coding> <system value="http://languageOID"/> <code value="en"/> </coding> </language> <referenceSource> <publicDomain value="true"/> <referenceSourceType> <coding> <system value="http://referencesourcetypeOID"/> <code value="CAS"/> </coding> </referenceSourceType> <referenceSourceClass> <coding> <system value="http://referencesourceclassOID"/> <code value="Othernamesource"/> </coding> </referenceSourceClass> <referenceSourceCitation value="CAS Registry Name"/> </referenceSource> </substanceName> <substanceName> <substanceName value="XYWZ123"/> <substanceNameType> <coding> <system value="http://substancenametypeOID"/> <code value="CompanyCode"/> </coding> </substanceNameType> <language> <coding> <system value="http://languageOID"/> <code value="en"/> </coding> </language> <referenceSource> <publicDomain value="false"/> <referenceSourceType> <coding> <system value="http://referencesourcetypeOID"/> <code value="MarketingAuthorizationApplication"/> </coding> </referenceSourceType> <referenceSourceClass> <coding> <system value="http://referencesourceclassOID"/> <code value="Regulatorysubmission"/> </coding> </referenceSourceClass> <referenceSourceId value="CBG345267C (Artificial ID)"/> </referenceSource> </substanceName --><SubstanceSourceMaterial xmlns="http://hl7.org/fhir"> <id value="example"/> </SubstanceSourceMaterial>
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.
FHIR ®© HL7.org 2011+. FHIR R6 hl7.fhir.core#6.0.0-ballot2 generated on Tue, Nov 12, 2024 03:29+0000.
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