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Clinical Genomics icon Work Group  Maturity Level: 0 Trial Use Use Context: Any

The canonical URL for this profile is:

http://hl7.org/fhir/StructureDefinition/sequence

FHIR Sequence Profile

This profile was published on Thu, Dec 21, 2023 00:00+0000 as a draft by HL7 International / Clinical Genomics.

Description of Profiles, Differentials, Snapshots, and how the XML and JSON presentations work.

This structure is derived from MolecularDefinition.

Summary

to do

Mandatory: 1 element
Prohibited: 2 elements

Structures

This structure refers to these other structures:

This indicates the differences between this profile and the base MolecularDefinition structure.

Name iconFlags iconCard. iconType iconDescription & Constraints icondoco icon
.. MolecularDefinition 0..* MolecularDefinition FHIR Sequence Profile
... type 1..1 code Sequence type, e.g., aa, dna, or rna
... location 0..0
... memberState 0..0
... representation
.... extracted
..... startingMolecule 1..1 Reference(Molecular Definition as Sequence Profile) Starting sequence
.... repeated
..... sequenceMotif 1..1 Reference(Molecular Definition as Sequence Profile) The sequence that defines the repeated motif
.... concatenated
..... sequenceElement
...... sequence 1..1 Reference(Molecular Definition as Sequence Profile) The Molecular Sequence corresponding to this element
.... relative
..... startingMolecule 1..1 Reference(Molecular Definition as Sequence Profile) The Molecular Sequence that serves as the starting sequence, on which edits will be applied
..... edit
...... replacementMolecule 1..1 Reference(Molecular Definition as Sequence Profile) The sequence that defines the replacement sequence used in the edit operation
...... replacedMolecule 0..1 Reference(Molecular Definition as Sequence Profile) The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit

doco Documentation for this format icon

This provides the consolidated view (aka snapshot) of the profile after applying the changes in this profile to the base MolecularDefinition structure.

Name iconFlags iconCard. iconType iconDescription & Constraints icondoco icon
.. MolecularDefinition 0..* MolecularDefinition FHIR Sequence Profile
... id Σ 0..1 id Logical id of this artifact
... meta Σ 0..1 Meta Metadata about the resource
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... language 0..1 code Language of the resource content
Binding: All Languages (required): IETF language tag for a human language

Additional BindingsPurpose
Common Languages Starter Set
... text 0..1 Narrative Text summary of the resource, for human interpretation
... contained 0..* Resource Contained, inline Resources
... extension 0..* Extension Additional content defined by implementations
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... identifier Σ 0..* Identifier Unique ID for this particular resource
... type Σ 1..1 code Sequence type, e.g., aa, dna, or rna
Binding: sequence Type (required): Type of a molecule -- DNA, RNA, or amino acid sequence.

... representation Σ 0..* BackboneElement Representation
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... focus Σ 0..1 CodeableConcept The focus of the representation
.... code Σ 0..* CodeableConcept A code of the representation
.... literal Σ 0..1 BackboneElement A literal representation
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... encoding Σ 0..1 CodeableConcept The encoding used for the expression of the primary sequence
..... value Σ 1..1 string The primary (linear) sequence, expressed as a literal string
.... resolvable Σ 0..1 Reference(DocumentReference) A resolvable representation of a molecule that optionally contains formatting in addition to the specification of the primary sequence itself
.... extracted Σ 0..1 BackboneElement A Molecular Sequence that is represented as an extracted portion of a different Molecular Sequence
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... startingMolecule Σ 1..1 Reference(Molecular Definition as Sequence Profile) Starting sequence
..... start Σ 1..1 integer The start coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted
..... end Σ 1..1 integer The end coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted
..... coordinateSystem Σ 1..1 CodeableConcept The coordinate system used to define the interval that defines the subsequence to be extracted. Coordinate systems are usually 0- or 1-based
..... reverseComplement Σ 0..1 boolean A flag that indicates whether the extracted sequence should be reverse complemented
.... repeated Σ 0..1 BackboneElement A Molecular Sequence that is represented as a repeated sequence motif
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... sequenceMotif Σ 1..1 Reference(Molecular Definition as Sequence Profile) The sequence that defines the repeated motif
..... copyCount Σ 1..1 integer The number of repeats (copies) of the sequence motif
.... concatenated Σ 0..1 BackboneElement A Molecular Sequence that is represented as an ordered concatenation of two or more Molecular Sequences
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... sequenceElement Σ 1..* BackboneElement One element of a concatenated Molecular Sequence
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... sequence Σ 1..1 Reference(Molecular Definition as Sequence Profile) The Molecular Sequence corresponding to this element
...... ordinalIndex Σ 1..1 integer The ordinal position of this sequence element within the concatenated Molecular Sequence
.... relative Σ 0..1 BackboneElement A Molecular Definition that is represented as an ordered series of edits on a specified starting sequence
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... startingMolecule Σ 1..1 Reference(Molecular Definition as Sequence Profile) The Molecular Sequence that serves as the starting sequence, on which edits will be applied
..... edit Σ 0..* BackboneElement An edit (change) made to a sequence
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... editOrder 0..1 integer The order of this edit, relative to other edits on the starting sequence
...... coordinateSystem Σ 1..1 CodeableConcept The coordinate system used to define the edited intervals on the starting sequence. Coordinate systems are usually 0- or 1-based
Binding: Genomic coordinate system. icon (extensible): Genomic coordinate system.

...... start Σ 1..1 integer The start coordinate of the interval that will be edited
...... end Σ 1..1 integer The end coordinate of the interval that will be edited
...... replacementMolecule Σ 1..1 Reference(Molecular Definition as Sequence Profile) The sequence that defines the replacement sequence used in the edit operation
...... replacedMolecule Σ 0..1 Reference(Molecular Definition as Sequence Profile) The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit

doco Documentation for this format icon
<!-- MolecularDefinitionSequence -->doco

<MolecularDefinition xmlns="http://hl7.org/fhir"
>
  <!-- from Element: extension -->
 <id value="[id]"/><!-- 0..1 Logical id of this artifact -->
 <meta><!-- I 0..1 Meta Metadata about the resource --></meta>
 <implicitRules value="[uri]"/><!-- I 0..1 A set of rules under which this content was created -->
 <language value="[code]"/><!-- I 0..1 Language of the resource content   -->
 <text><!-- I 0..1 Narrative 
     Text summary of the resource, for human interpretation --></text>
 <contained><!-- 0..* Resource 
     Contained, inline Resources --></contained>
 <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored  --></modifierExtension>
 <identifier><!-- I 0..* Identifier 
     Unique ID for this particular resource --></identifier>
 <type value="[code]"/><!-- I 1..1 Sequence type, e.g., aa, dna, or rna   -->
 <location> I 0..0 BackboneElement  <!-- I 0..0 Location of this molecule -->
 </location>
 <memberState><!-- I 0..0 Reference(MolecularDefinition) Member --></memberState>
 <representation> I 0..* BackboneElement  <!-- I 0..* Representation -->
  <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
  <focus><!-- I 0..1 CodeableConcept 
      The focus of the representation --></focus>
  <code><!-- I 0..* CodeableConcept 
      A code of the representation --></code>
  <literal> I 0..1 BackboneElement  <!-- I 0..1 A literal representation -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <encoding><!-- I 0..1 
     CodeableConcept 
       The encoding used for the expression of the primary sequence --></encoding>
   <value value="[string]"/><!-- I 1..1 
       The primary (linear) sequence, expressed as a literal string -->
  </literal>
  <resolvable><!-- I 0..1 Reference(DocumentReference) 
      A resolvable representation of a molecule that optionally contains formatting in addition to the specification of the primary sequence itself --></resolvable>
  <extracted> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as an extracted portion of a different Molecular Sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <startingMolecule><!-- I 1..1 
     Reference(MolecularDefinitionSequence) Starting sequence --></startingMolecule>
   <start value="[integer]"/><!-- I 1..1 
       The start coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted -->
   <end value="[integer]"/><!-- I 1..1 
       The end coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted -->
   <coordinateSystem><!-- I 1..1 
     CodeableConcept 
       The coordinate system used to define the interval that defines the subsequence to be extracted. Coordinate systems are usually 0- or 1-based --></coordinateSystem>
   <reverseComplement value="[boolean]"/><!-- I 0..1 
       A flag that indicates whether the extracted sequence should be reverse complemented -->
  </extracted>
  <repeated> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as a repeated sequence motif -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceMotif><!-- I 1..1 
     Reference(MolecularDefinitionSequence) 
       The sequence that defines the repeated motif --></sequenceMotif>
   <copyCount value="[integer]"/><!-- I 1..1 
       The number of repeats (copies) of the sequence motif -->
  </repeated>
  <concatenated> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as an ordered concatenation of two or more Molecular Sequences -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceElement> I 1..* 
     BackboneElement  <!-- I 1..* One element of a concatenated Molecular Sequence -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <sequence><!-- I 1..1 
      Reference(MolecularDefinitionSequence) 
        The Molecular Sequence corresponding to this element --></sequence>
    <ordinalIndex value="[integer]"/><!-- I 1..1 
        The ordinal position of this sequence element within the concatenated Molecular Sequence -->
   </sequenceElement>
  </concatenated>
  <relative> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Definition that is represented as an ordered series of edits on a specified starting sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <startingMolecule><!-- I 1..1 
     Reference(MolecularDefinitionSequence) 
       The Molecular Sequence that serves as the starting sequence, on which edits will be applied --></startingMolecule>
   <edit> I 0..* BackboneElement  <!-- I 0..* An edit (change) made to a sequence -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <editOrder value="[integer]"/><!-- I 0..1 
        The order of this edit, relative to other edits on the starting sequence -->
    <coordinateSystem><!-- I 1..1 
      CodeableConcept The coordinate system used to define the edited intervals on the starting sequence. Coordinate systems are usually 0- or 1-based icon   --></coordinateSystem>
    <start value="[integer]"/><!-- I 1..1 
        The start coordinate of the interval that will be edited -->
    <end value="[integer]"/><!-- I 1..1 
        The end coordinate of the interval that will be edited -->
    <replacementMolecule><!-- I 1..1 
      Reference(MolecularDefinitionSequence) 
        The sequence that defines the replacement sequence used in the edit operation --></replacementMolecule>
    <replacedMolecule><!-- I 0..1 
      Reference(MolecularDefinitionSequence) 
        The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit --></replacedMolecule>
   </edit>
  </relative>
 </representation>
</MolecularDefinition>
{ // MolecularDefinitionSequence
  // from Element: extension
    "meta" : { Meta }, // IMetadata about the resource
    "implicitRules" : "<uri>", // IA set of rules under which this content was created
    "language" : "<code>", // ILanguage of the resource content
    "text" : { Narrative }, // IText summary of the resource, for human interpretation
    "contained" : [{ Resource }], //Contained, inline Resources
    "modifierExtension" : [{ Extension }], // IExtensions that cannot be ignored
    "identifier" : [{ Identifier }], // IUnique ID for this particular resource
    "type" : "<code>", // I R! Sequence type, e.g., aa, dna, or rna
    "representation" : [{ BackboneElement }] // IRepresentation
  }

This structure is derived from MolecularDefinition.

Summary

to do

Mandatory: 1 element
Prohibited: 2 elements

Structures

This structure refers to these other structures:

Differential View

This indicates the differences between this profile and the base MolecularDefinition structure.

Name iconFlags iconCard. iconType iconDescription & Constraints icondoco icon
.. MolecularDefinition 0..* MolecularDefinition FHIR Sequence Profile
... type 1..1 code Sequence type, e.g., aa, dna, or rna
... location 0..0
... memberState 0..0
... representation
.... extracted
..... startingMolecule 1..1 Reference(Molecular Definition as Sequence Profile) Starting sequence
.... repeated
..... sequenceMotif 1..1 Reference(Molecular Definition as Sequence Profile) The sequence that defines the repeated motif
.... concatenated
..... sequenceElement
...... sequence 1..1 Reference(Molecular Definition as Sequence Profile) The Molecular Sequence corresponding to this element
.... relative
..... startingMolecule 1..1 Reference(Molecular Definition as Sequence Profile) The Molecular Sequence that serves as the starting sequence, on which edits will be applied
..... edit
...... replacementMolecule 1..1 Reference(Molecular Definition as Sequence Profile) The sequence that defines the replacement sequence used in the edit operation
...... replacedMolecule 0..1 Reference(Molecular Definition as Sequence Profile) The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit

doco Documentation for this format icon

Snapshot View

This provides the consolidated view (aka snapshot) of the profile after applying the changes in this profile to the base MolecularDefinition structure.

Name iconFlags iconCard. iconType iconDescription & Constraints icondoco icon
.. MolecularDefinition 0..* MolecularDefinition FHIR Sequence Profile
... id Σ 0..1 id Logical id of this artifact
... meta Σ 0..1 Meta Metadata about the resource
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... language 0..1 code Language of the resource content
Binding: All Languages (required): IETF language tag for a human language

Additional BindingsPurpose
Common Languages Starter Set
... text 0..1 Narrative Text summary of the resource, for human interpretation
... contained 0..* Resource Contained, inline Resources
... extension 0..* Extension Additional content defined by implementations
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... identifier Σ 0..* Identifier Unique ID for this particular resource
... type Σ 1..1 code Sequence type, e.g., aa, dna, or rna
Binding: sequence Type (required): Type of a molecule -- DNA, RNA, or amino acid sequence.

... representation Σ 0..* BackboneElement Representation
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... focus Σ 0..1 CodeableConcept The focus of the representation
.... code Σ 0..* CodeableConcept A code of the representation
.... literal Σ 0..1 BackboneElement A literal representation
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... encoding Σ 0..1 CodeableConcept The encoding used for the expression of the primary sequence
..... value Σ 1..1 string The primary (linear) sequence, expressed as a literal string
.... resolvable Σ 0..1 Reference(DocumentReference) A resolvable representation of a molecule that optionally contains formatting in addition to the specification of the primary sequence itself
.... extracted Σ 0..1 BackboneElement A Molecular Sequence that is represented as an extracted portion of a different Molecular Sequence
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... startingMolecule Σ 1..1 Reference(Molecular Definition as Sequence Profile) Starting sequence
..... start Σ 1..1 integer The start coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted
..... end Σ 1..1 integer The end coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted
..... coordinateSystem Σ 1..1 CodeableConcept The coordinate system used to define the interval that defines the subsequence to be extracted. Coordinate systems are usually 0- or 1-based
..... reverseComplement Σ 0..1 boolean A flag that indicates whether the extracted sequence should be reverse complemented
.... repeated Σ 0..1 BackboneElement A Molecular Sequence that is represented as a repeated sequence motif
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... sequenceMotif Σ 1..1 Reference(Molecular Definition as Sequence Profile) The sequence that defines the repeated motif
..... copyCount Σ 1..1 integer The number of repeats (copies) of the sequence motif
.... concatenated Σ 0..1 BackboneElement A Molecular Sequence that is represented as an ordered concatenation of two or more Molecular Sequences
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... sequenceElement Σ 1..* BackboneElement One element of a concatenated Molecular Sequence
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... sequence Σ 1..1 Reference(Molecular Definition as Sequence Profile) The Molecular Sequence corresponding to this element
...... ordinalIndex Σ 1..1 integer The ordinal position of this sequence element within the concatenated Molecular Sequence
.... relative Σ 0..1 BackboneElement A Molecular Definition that is represented as an ordered series of edits on a specified starting sequence
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... startingMolecule Σ 1..1 Reference(Molecular Definition as Sequence Profile) The Molecular Sequence that serves as the starting sequence, on which edits will be applied
..... edit Σ 0..* BackboneElement An edit (change) made to a sequence
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... editOrder 0..1 integer The order of this edit, relative to other edits on the starting sequence
...... coordinateSystem Σ 1..1 CodeableConcept The coordinate system used to define the edited intervals on the starting sequence. Coordinate systems are usually 0- or 1-based
Binding: Genomic coordinate system. icon (extensible): Genomic coordinate system.

...... start Σ 1..1 integer The start coordinate of the interval that will be edited
...... end Σ 1..1 integer The end coordinate of the interval that will be edited
...... replacementMolecule Σ 1..1 Reference(Molecular Definition as Sequence Profile) The sequence that defines the replacement sequence used in the edit operation
...... replacedMolecule Σ 0..1 Reference(Molecular Definition as Sequence Profile) The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit

doco Documentation for this format icon

XML Template

<!-- MolecularDefinitionSequence -->doco

<MolecularDefinition xmlns="http://hl7.org/fhir"
>
  <!-- from Element: extension -->
 <id value="[id]"/><!-- 0..1 Logical id of this artifact -->
 <meta><!-- I 0..1 Meta Metadata about the resource --></meta>
 <implicitRules value="[uri]"/><!-- I 0..1 A set of rules under which this content was created -->
 <language value="[code]"/><!-- I 0..1 Language of the resource content   -->
 <text><!-- I 0..1 Narrative 
     Text summary of the resource, for human interpretation --></text>
 <contained><!-- 0..* Resource 
     Contained, inline Resources --></contained>
 <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored  --></modifierExtension>
 <identifier><!-- I 0..* Identifier 
     Unique ID for this particular resource --></identifier>
 <type value="[code]"/><!-- I 1..1 Sequence type, e.g., aa, dna, or rna   -->
 <location> I 0..0 BackboneElement  <!-- I 0..0 Location of this molecule -->
 </location>
 <memberState><!-- I 0..0 Reference(MolecularDefinition) Member --></memberState>
 <representation> I 0..* BackboneElement  <!-- I 0..* Representation -->
  <modifierExtension><!-- I 0..* Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
  <focus><!-- I 0..1 CodeableConcept 
      The focus of the representation --></focus>
  <code><!-- I 0..* CodeableConcept 
      A code of the representation --></code>
  <literal> I 0..1 BackboneElement  <!-- I 0..1 A literal representation -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <encoding><!-- I 0..1 
     CodeableConcept 
       The encoding used for the expression of the primary sequence --></encoding>
   <value value="[string]"/><!-- I 1..1 
       The primary (linear) sequence, expressed as a literal string -->
  </literal>
  <resolvable><!-- I 0..1 Reference(DocumentReference) 
      A resolvable representation of a molecule that optionally contains formatting in addition to the specification of the primary sequence itself --></resolvable>
  <extracted> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as an extracted portion of a different Molecular Sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <startingMolecule><!-- I 1..1 
     Reference(MolecularDefinitionSequence) Starting sequence --></startingMolecule>
   <start value="[integer]"/><!-- I 1..1 
       The start coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted -->
   <end value="[integer]"/><!-- I 1..1 
       The end coordinate (on the parent sequence) of the interval that defines the subsequence to be extracted -->
   <coordinateSystem><!-- I 1..1 
     CodeableConcept 
       The coordinate system used to define the interval that defines the subsequence to be extracted. Coordinate systems are usually 0- or 1-based --></coordinateSystem>
   <reverseComplement value="[boolean]"/><!-- I 0..1 
       A flag that indicates whether the extracted sequence should be reverse complemented -->
  </extracted>
  <repeated> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as a repeated sequence motif -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceMotif><!-- I 1..1 
     Reference(MolecularDefinitionSequence) 
       The sequence that defines the repeated motif --></sequenceMotif>
   <copyCount value="[integer]"/><!-- I 1..1 
       The number of repeats (copies) of the sequence motif -->
  </repeated>
  <concatenated> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Sequence that is represented as an ordered concatenation of two or more Molecular Sequences -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <sequenceElement> I 1..* 
     BackboneElement  <!-- I 1..* One element of a concatenated Molecular Sequence -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <sequence><!-- I 1..1 
      Reference(MolecularDefinitionSequence) 
        The Molecular Sequence corresponding to this element --></sequence>
    <ordinalIndex value="[integer]"/><!-- I 1..1 
        The ordinal position of this sequence element within the concatenated Molecular Sequence -->
   </sequenceElement>
  </concatenated>
  <relative> I 0..1 BackboneElement  <!-- I 0..1 A Molecular Definition that is represented as an ordered series of edits on a specified starting sequence -->
   <modifierExtension><!-- I 0..* 
     Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
   <startingMolecule><!-- I 1..1 
     Reference(MolecularDefinitionSequence) 
       The Molecular Sequence that serves as the starting sequence, on which edits will be applied --></startingMolecule>
   <edit> I 0..* BackboneElement  <!-- I 0..* An edit (change) made to a sequence -->
    <modifierExtension><!-- I 0..* 
      Extension  Extensions that cannot be ignored even if unrecognized  --></modifierExtension>
    <editOrder value="[integer]"/><!-- I 0..1 
        The order of this edit, relative to other edits on the starting sequence -->
    <coordinateSystem><!-- I 1..1 
      CodeableConcept The coordinate system used to define the edited intervals on the starting sequence. Coordinate systems are usually 0- or 1-based icon   --></coordinateSystem>
    <start value="[integer]"/><!-- I 1..1 
        The start coordinate of the interval that will be edited -->
    <end value="[integer]"/><!-- I 1..1 
        The end coordinate of the interval that will be edited -->
    <replacementMolecule><!-- I 1..1 
      Reference(MolecularDefinitionSequence) 
        The sequence that defines the replacement sequence used in the edit operation --></replacementMolecule>
    <replacedMolecule><!-- I 0..1 
      Reference(MolecularDefinitionSequence) 
        The sequence on the 'starting' sequence for the edit operation, defined by the specified interval, that will be replaced during the edit --></replacedMolecule>
   </edit>
  </relative>
 </representation>
</MolecularDefinition>

JSON Template

{ // MolecularDefinitionSequence
  // from Element: extension
    "meta" : { Meta }, // IMetadata about the resource
    "implicitRules" : "<uri>", // IA set of rules under which this content was created
    "language" : "<code>", // ILanguage of the resource content
    "text" : { Narrative }, // IText summary of the resource, for human interpretation
    "contained" : [{ Resource }], //Contained, inline Resources
    "modifierExtension" : [{ Extension }], // IExtensions that cannot be ignored
    "identifier" : [{ Identifier }], // IUnique ID for this particular resource
    "type" : "<code>", // I R! Sequence type, e.g., aa, dna, or rna
    "representation" : [{ BackboneElement }] // IRepresentation
  }

 

Alternate definitions: Master Definition (XML, JSON), Schematron

Path Name Conformance ValueSet
MolecularDefinition.language All Languages required All Languages
MolecularDefinition.type sequence Type required sequence Type
MolecularDefinition.representation.relative.edit.coordinateSystem ?ext extensible http://loinc.org/LL5323-2/ icon
. .