Polymer substance: Polyethylene Glycol 3350 — linear homopolymer of ethylene oxide (id = "peg3350")

<?xml version="1.0" encoding="UTF-8"?>

<!--  Example: Polyethylene Glycol 3350 (PEG 3350) — a homopolymer of ethylene
     oxide with number-average molecular weight ~3350 Da. Demonstrates the new
     SubstanceDefinition polymer backbones added for FHIR-57660: .polymer.class,
     .geometry, .monomerSet.startingMaterial, .repeat.repeatUnit with degree
     of polymerisation. Adapted from ISO 11238 Implementation Guide polymer
     example for PEG 3350.  --><SubstanceDefinition xmlns="http://hl7.org/fhir">
  <id value="peg3350"/> 
  <identifier> 
    <system value="http://example.europa.eu/fhir/SMSId"/> 
    <value value="PEG3350P"/> 
  </identifier> 
  <status> 
    <coding> 
      <system value="http://hl7.org/fhir/publication-status"/> 
      <code value="active"/> 
      <display value="Active"/> 
    </coding> 
  </status> 
  <classification> 
    <coding> 
      <system value="http://example.europa.eu/fhir/SubstanceType"/> 
      <code value="polymer"/> 
      <display value="Polymer"/> 
    </coding> 
  </classification> 
  <domain> 
    <coding> 
      <system value="http://example.europa.eu/fhir/Domain"/> 
      <code value="human"/> 
      <display value="Human use"/> 
    </coding> 
  </domain> 
  <description value="Polyethylene Glycol 3350 (PEG 3350, Macrogol 3350) — a synthetic polyether of ethylene
   oxide with number-average molecular weight approximately 3350 Da. Linear homopolymer
   used as an osmotic laxative and a pharmaceutical excipient."/> 
  <code> 
    <code> 
      <coding> 
        <system value="http://example.europa.eu/fhir/Substance"/> 
        <code value="PEG3350P"/> 
      </coding> 
    </code> 
  </code> 
  <name> 
    <name value="Polyethylene Glycol 3350"/> 
    <preferred value="true"/> 
    <language> 
      <coding> 
        <system value="urn:ietf:bcp:47"/> 
        <code value="en"/> 
        <display value="English"/> 
      </coding> 
    </language> 
    <official> 
      <authority> 
        <coding> 
          <system value="http://hl7.org/fhir/substance-name-authority"/> 
          <code value="USAN"/> 
          <display value="USAN"/> 
        </coding> 
      </authority> 
      <status> 
        <coding> 
          <system value="http://hl7.org/fhir/publication-status"/> 
          <code value="active"/> 
          <display value="Active"/> 
        </coding> 
      </status> 
    </official> 
  </name> 
  <name> 
    <name value="Macrogol 3350"/> 
    <preferred value="false"/> 
  </name> 
  <molecularWeight> 
    <type> 
      <coding> 
        <system value="http://example.europa.eu/fhir/WeightType"/> 
        <code value="number-average"/> 
        <display value="Number average (Mn)"/> 
      </coding> 
    </type> 
    <amount> 
      <value value="3350"/> 
      <unit value="g/mol"/> 
      <system value="http://unitsofmeasure.org"/> 
      <code value="g/mol"/> 
    </amount> 
  </molecularWeight> 
  <polymer> 
    <class> 
      <coding> 
        <system value="http://hl7.org/fhir/polymer-class"/> 
        <code value="homopolymer"/> 
        <display value="Homopolymer"/> 
      </coding> 
    </class> 
    <geometry> 
      <coding> 
        <system value="http://hl7.org/fhir/polymer-geometry"/> 
        <code value="linear"/> 
        <display value="Linear"/> 
      </coding> 
    </geometry> 
    <monomerSet> 
      <ratioType> 
        <coding> 
          <system value="http://hl7.org/fhir/polymer-monomer-ratio-type"/> 
          <code value="monomer-polymer-ratio"/> 
          <display value="Monomer/Polymer ratio"/> 
        </coding> 
      </ratioType> 
      <startingMaterial> 
        <code> 
          <concept> 
            <coding> 
              <system value="http://example.europa.eu/fhir/Substance"/> 
              <code value="ethylene-oxide"/> 
              <display value="Ethylene oxide"/> 
            </coding> 
          </concept> 
        </code> 
        <category> 
          <coding> 
            <system value="http://hl7.org/fhir/polymer-starting-material-category"/> 
            <code value="chemical-substance"/> 
            <display value="Chemical substance"/> 
          </coding> 
        </category> 
        <isDefining value="true"/> 
        <amount> 
          <value value="76"/> 
          <unit value="monomers per polymer"/> 
        </amount> 
      </startingMaterial> 
    </monomerSet> 
    <repeat> 
      <averageMolecularFormula value="(C2H4O)76"/> 
      <repeatUnitAmountType> 
        <coding> 
          <system value="http://hl7.org/fhir/polymer-monomer-ratio-type"/> 
          <code value="sru-polymer-ratio"/> 
          <display value="SRU/Polymer ratio"/> 
        </coding> 
      </repeatUnitAmountType> 
      <repeatUnit> 
        <unit value="-CH2-CH2-O-"/> 
        <orientation> 
          <coding> 
            <system value="http://hl7.org/fhir/polymerisation-orientation"/> 
            <code value="head-tail"/> 
            <display value="Head-to-tail"/> 
          </coding> 
        </orientation> 
        <amount value="76"/> 
        <degreeOfPolymerisation> 
          <type> 
            <coding> 
              <system value="http://hl7.org/fhir/degree-of-polymerisation-type"/> 
              <code value="number-average"/> 
              <display value="Number average"/> 
            </coding> 
          </type> 
          <average value="76"/> 
          <low value="70"/> 
          <high value="82"/> 
        </degreeOfPolymerisation> 
      </repeatUnit> 
    </repeat> 
  </polymer> 
</SubstanceDefinition>