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Example SubstanceDefinition/peg3350 (JSON)

Responsible Owner: Biomedical Research and Regulation Work GroupStandards Status: InformativeCompartments: No defined compartments

Raw JSON (canonical form + also see JSON Format Specification)

Polymer substance: Polyethylene Glycol 3350 — linear homopolymer of ethylene oxide

{
  "resourceType" : "SubstanceDefinition",
  "id" : "peg3350",
  "identifier" : [{
    "system" : "http://example.europa.eu/fhir/SMSId",
    "value" : "PEG3350P"
  }],
  "status" : {
    "coding" : [{
      "system" : "http://hl7.org/fhir/publication-status",
      "code" : "active",
      "display" : "Active"
    }]
  },
  "classification" : [{
    "coding" : [{
      "system" : "http://example.europa.eu/fhir/SubstanceType",
      "code" : "polymer",
      "display" : "Polymer"
    }]
  }],
  "domain" : {
    "coding" : [{
      "system" : "http://example.europa.eu/fhir/Domain",
      "code" : "human",
      "display" : "Human use"
    }]
  },
  "description" : "Polyethylene Glycol 3350 (PEG 3350, Macrogol 3350) — a synthetic polyether of ethylene oxide with number-average molecular weight approximately 3350 Da. Linear homopolymer used as an osmotic laxative and a pharmaceutical excipient.",
  "code" : [{
    "code" : {
      "coding" : [{
        "system" : "http://example.europa.eu/fhir/Substance",
        "code" : "PEG3350P"
      }]
    }
  }],
  "name" : [{
    "name" : "Polyethylene Glycol 3350",
    "preferred" : true,
    "language" : [{
      "coding" : [{
        "system" : "urn:ietf:bcp:47",
        "code" : "en",
        "display" : "English"
      }]
    }],
    "official" : [{
      "authority" : {
        "coding" : [{
          "system" : "http://hl7.org/fhir/substance-name-authority",
          "code" : "USAN",
          "display" : "USAN"
        }]
      },
      "status" : {
        "coding" : [{
          "system" : "http://hl7.org/fhir/publication-status",
          "code" : "active",
          "display" : "Active"
        }]
      }
    }]
  },
  {
    "name" : "Macrogol 3350",
    "preferred" : false
  }],
  "molecularWeight" : [{
    "type" : {
      "coding" : [{
        "system" : "http://example.europa.eu/fhir/WeightType",
        "code" : "number-average",
        "display" : "Number average (Mn)"
      }]
    },
    "amount" : {
      "value" : 3350,
      "unit" : "g/mol",
      "system" : "http://unitsofmeasure.org",
      "code" : "g/mol"
    }
  }],
  "polymer" : {
    "class" : {
      "coding" : [{
        "system" : "http://hl7.org/fhir/polymer-class",
        "code" : "homopolymer",
        "display" : "Homopolymer"
      }]
    },
    "geometry" : {
      "coding" : [{
        "system" : "http://hl7.org/fhir/polymer-geometry",
        "code" : "linear",
        "display" : "Linear"
      }]
    },
    "monomerSet" : [{
      "ratioType" : {
        "coding" : [{
          "system" : "http://hl7.org/fhir/polymer-monomer-ratio-type",
          "code" : "monomer-polymer-ratio",
          "display" : "Monomer/Polymer ratio"
        }]
      },
      "startingMaterial" : [{
        "code" : {
          "concept" : {
            "coding" : [{
              "system" : "http://example.europa.eu/fhir/Substance",
              "code" : "ethylene-oxide",
              "display" : "Ethylene oxide"
            }]
          }
        },
        "category" : {
          "coding" : [{
            "system" : "http://hl7.org/fhir/polymer-starting-material-category",
            "code" : "chemical-substance",
            "display" : "Chemical substance"
          }]
        },
        "isDefining" : true,
        "amount" : {
          "value" : 76,
          "unit" : "monomers per polymer"
        }
      }]
    }],
    "repeat" : [{
      "averageMolecularFormula" : "(C2H4O)76",
      "repeatUnitAmountType" : {
        "coding" : [{
          "system" : "http://hl7.org/fhir/polymer-monomer-ratio-type",
          "code" : "sru-polymer-ratio",
          "display" : "SRU/Polymer ratio"
        }]
      },
      "repeatUnit" : [{
        "unit" : "-CH2-CH2-O-",
        "orientation" : {
          "coding" : [{
            "system" : "http://hl7.org/fhir/polymerisation-orientation",
            "code" : "head-tail",
            "display" : "Head-to-tail"
          }]
        },
        "amount" : 76,
        "degreeOfPolymerisation" : [{
          "type" : {
            "coding" : [{
              "system" : "http://hl7.org/fhir/degree-of-polymerisation-type",
              "code" : "number-average",
              "display" : "Number average"
            }]
          },
          "average" : 76,
          "low" : 70,
          "high" : 82
        }]
      }]
    }]
  }
}

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.