FHIR CI-Build

This is the Continuous Integration Build of FHIR (will be incorrect/inconsistent at times).
See the Directory of published versions icon

14.13 Resource Evidence - Content

Clinical Decision Support icon Work GroupMaturity Level: 1 Trial UseSecurity Category: Business Compartments: No defined compartments

The Evidence Resource provides a machine-interpretable expression of an evidence concept including the evidence variables (e.g., population, exposures/interventions, comparators, outcomes, measured variables, confounding variables), the statistics, and the certainty of this evidence.

14.13.1 Scope and Usage

The Evidence Resource enables the expression of the most granular form of evidence, such as the actual quantitative results of a study or scientific analysis.

Human-readable summaries of the Evidence Resource may be expressed in description, assertion, and note elements. The description element is typically used for the primary expression. The assertion element is less commonly used and is typically used for interpretive expression. The note element may be used for any number of explanatory, variant, or related comments.

The variableDefinition element is used to describe what the evidence is about. Each variable defined must be assigned a variable role which signals how that variable is used in the statistics within the Evidence Resource. The variable definition may be expressed in human-readable form (with a description element) and/or expressed in computable form by referencing Group or EvidenceVariable Resources. In general, Group Resources are used to define populations and EvidenceVariable Resources are used to define measured variables (exposures, outcomes, and covariates). The variableDefinition element allows expression of the observed variable and the intended variable. In many forms of expression the Evidence is interpreted for a specific context and recognition of both observed and intended variables is important for understanding the applicability and certainty of the evidence.

The heart of the evidence is the statistic. The statistic BackboneElement provides a machine-interpretable expression of a statistic, including the quantity; unit of measure; classification of statistic type; sample size; attributes such as confidence intervals, p values, and heterogeneity estimates; and statistic model characteristics. An Evidence Resource may contain more than one statistic, in which case each statistic matches the same combination of variable definitions.

Because a statistic can rarely be interpreted without knowing how it was obtained, the Evidence Resource enables expression of the studyDesign. For evidence derived from synthesis of evidence, the Evidence Resource enables expression of the synthesisType.

The certainty element provides a machine-interpretable expression of certainty, confidence or quality of the resource in which it is included. The certainty element can express overall certainty and certainty of any subcomponent concepts using codeable concepts from structured rating systems. The certainty element enables machine-to-machine communication of the certainty of evidence.

14.13.2 Boundaries and Relationships

The Evidence Resource is the central atomic component for the Evidence-related Resources. The Evidence Resource may reference multiple Group and EvidenceVariable Resources; in these cases, the Group and EvidenceVariable Resources to which an Evidence Resource points does not refer back to the Evidence. In the context of evidence synthesis, a List Resource may reference Evidence Resources where the List Resource is used to define the set of evidence being synthesized.

14.13.3 References to this Resource

No references for this Resource.

14.13.4 Resource Content

Structure

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence TU DomainResource Single evidence bit
+ Warning: Name should be usable as an identifier for the module by machine processing applications such as code generation

Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension
Interfaces Implemented: MetadataResource
... url ΣC 0..1 uri Canonical identifier for this evidence, represented as a globally unique URI
+ Warning: URL should not contain | or # - these characters make processing canonical references problematic
... identifier Σ 0..* Identifier Additional identifier for the summary

... version Σ 0..1 string Business version of this summary
... versionAlgorithm[x] Σ 0..1 How to compare versions
Binding: Version Algorithm (Extensible)
.... versionAlgorithmString string
.... versionAlgorithmCoding Coding
... name C 0..1 string Name for this summary (machine friendly)
... title ΣT 0..1 string Name for this summary (human friendly)
... citeAs[x] 0..1 Citation for this evidence
.... citeAsReference Reference(Citation)
.... citeAsMarkdown markdown
... status ?!Σ 1..1 code draft | active | retired | unknown
Binding: PublicationStatus (Required)
... experimental 0..1 boolean For testing purposes, not real usage
... date Σ 0..1 dateTime Date last changed
... approvalDate 0..1 date When the summary was approved by publisher
... lastReviewDate 0..1 date When the summary was last reviewed by the publisher
... author Σ 0..* ContactDetail Who authored the content

... publisher ΣT 0..1 string Name of the publisher/steward (organization or individual)
... contact Σ 0..* ContactDetail Contact details for the publisher

... recorder 0..* ContactDetail Who entered the data for the evidence

... editor 0..* ContactDetail Who edited the content

... reviewer 0..* ContactDetail Who reviewed the content

... endorser 0..* ContactDetail Who endorsed the content

... useContext Σ 0..* UsageContext The context that the content is intended to support

... purpose 0..1 markdown Why this Evidence is defined
... copyright 0..1 markdown Intellectual property ownership, may include restrictions on use
... copyrightLabel T 0..1 string Copyright holder and year(s)
... relatedArtifact 0..* RelatedArtifact Link or citation to artifact associated with the summary

... description ΣT 0..1 markdown Description of the particular summary
... assertion T 0..1 markdown Declarative description of the Evidence
... note 0..* Annotation Footnotes and/or explanatory notes

... variableDefinition 0..* BackboneElement Description, classification, and definition of a single variable

.... description 0..1 markdown A text description or summary of the variable
.... note 0..* Annotation Footnotes and/or explanatory notes

.... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: Evidence Variable Role (Required)
.... roleSubtype 0..1 CodeableConcept Sub-classification of the role of the variable
Binding: Evidence Variable Role Subtype (Extensible)
.... comparatorCategory 0..1 string The reference value used for comparison
.... observed Σ 0..1 Reference(Group | EvidenceVariable) Definition of the actual variable related to the statistic(s)
.... intended 0..1 Reference(Group | EvidenceVariable) Definition of the intended variable related to the Evidence
.... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
Binding: EvidenceDirectness icon (Extensible)
... synthesisType 0..* CodeableConcept The design of the synthesis (combination of studies) that produced this evidence
Binding: StatisticSynthesisType icon (Extensible)

... studyDesign 0..* CodeableConcept The design of the study that produced this evidence
Binding: Study Design (Extensible)

... statistic 0..* BackboneElement Values and parameters for a single statistic

.... description 0..1 markdown A natural language summary of the statistic
.... note 0..* Annotation Footnotes and/or explanatory notes

.... statisticType Σ 0..1 CodeableConcept Type of statistic, e.g., relative risk
Binding: Statistic Type (Extensible)
.... category 0..1 CodeableConcept Associated category for categorical variable
.... quantity Σ 0..1 Quantity Statistic value
.... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
.... numberAffected 0..1 unsignedInt The number of participants affected
.... sampleSize 0..1 BackboneElement Count of participants in the study sample
..... description 0..1 markdown Textual description of sample size for statistic
..... note 0..* Annotation Footnote or explanatory note about the sample size

..... numberOfStudies 0..1 unsignedInt Number of contributing studies
..... numberOfParticipants 0..1 unsignedInt Total number of participants
..... knownDataCount 0..1 unsignedInt Number of participants with known results for measured variables
.... attributeEstimate 0..* BackboneElement An attribute of the Statistic

..... description 0..1 markdown Textual description of the attribute estimate
..... note 0..* Annotation Footnote or explanatory note about the estimate

..... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: Attribute Estimate Type (Extensible)
..... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measure
..... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
..... range 0..1 Range Lower and upper bound values of the attribute estimate
..... attributeEstimate 0..* see attributeEstimate A nested attribute estimate; which is the attribute estimate of an attribute estimate

.... modelCharacteristic 0..* BackboneElement An aspect of the statistical model

..... code 1..1 CodeableConcept Model specification
Binding: Statistic Model Code (Extensible)
..... value[x] 0..1 The specific value (when paired with code)
...... valueQuantity SimpleQuantity
...... valueRange Range
...... valueCodeableConcept CodeableConcept
..... intended 0..1 boolean The plan for analysis
..... applied 0..1 boolean This model characteristic is part of the analysis that was applied, whether or not the analysis followed the plan
..... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis

...... variableDefinition 1..1 Reference(Group | EvidenceVariable) Description and definition of the variable
...... handling 0..1 code continuous | dichotomous | ordinal | polychotomous
Binding: Evidence Variable Handling (Required)
...... valueCategory 0..* CodeableConcept Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable

...... valueQuantity 0..* Quantity Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable

...... valueRange 0..* Range Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variable

..... attribute 0..* see attributeEstimate An attribute of the model characteristic

... certainty 0..* BackboneElement Certainty or quality of the evidence

.... description 0..1 markdown Textual description of certainty
.... note 0..* Annotation Footnotes and/or explanatory notes

.... type 0..1 CodeableConcept Aspect of certainty being rated
Binding: Evidence Certainty Type (Extensible)
.... rating 0..* CodeableConcept Assessment or judgement of the aspect
Binding: Evidence Certainty Rating (Extensible)

.... rater 0..1 string Individual or group who did the rating
.... subcomponent 0..* see certainty A domain or subdomain of certainty


doco Documentation for this format icon

See the Extensions for this resource

UML Diagram (Legend)

Evidence (DomainResource) +MetadataResourceAn absolute URI that is used to identify this evidence when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which an authoritative instance of this summary is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the summary is stored on different serversurl : uri [0..1]A formal identifier that is used to identify this summary when it is represented in other formats, or referenced in a specification, model, design or an instanceidentifier : Identifier [0..*]The identifier that is used to identify this version of the summary when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the summary author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequenceversion : string [0..1]Indicates the mechanism used to compare versions to determine which is more currentversionAlgorithm[x] : DataType [0..1] « string|Coding; null (Strength=Extensible) VersionAlgorithm+ »A natural language name identifying the evidence. This name should be usable as an identifier for the module by machine processing applications such as code generationname : string [0..1] « This element has or is affected by some invariantsC »A short, descriptive, user-friendly title for the summarytitle : string [0..1]Citation Resource or display of suggested citation for this evidenceciteAs[x] : DataType [0..1] « Reference(Citation)|markdown »The status of this summary. Enables tracking the life-cycle of the content (this element modifies the meaning of other elements)status : code [1..1] « null (Strength=Required)PublicationStatus! »A Boolean value to indicate that this resource is authored for testing purposes (or education/evaluation/marketing) and is not intended to be used for genuine usageexperimental : boolean [0..1]The date (and optionally time) when the summary was last significantly changed. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the summary changesdate : dateTime [0..1]The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usageapprovalDate : date [0..1]The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval datelastReviewDate : date [0..1]An individiual, organization, or device primarily involved in the creation and maintenance of the contentauthor : ContactDetail [0..*]The name of the organization or individual responsible for the release and ongoing maintenance of the evidencepublisher : string [0..1]Contact details to assist a user in finding and communicating with the publishercontact : ContactDetail [0..*]Who entered the data for the evidencerecorder : ContactDetail [0..*]An individiual, organization, or device primarily responsible for internal coherence of the contenteditor : ContactDetail [0..*]An individiual, organization, or device primarily responsible for review of some aspect of the contentreviewer : ContactDetail [0..*]An individiual, organization, or device responsible for officially endorsing the content for use in some settingendorser : ContactDetail [0..*]The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate evidence instancesuseContext : UsageContext [0..*]Explanation of why this Evidence is needed and why it has been designed as it haspurpose : markdown [0..1]A copyright statement relating to the Evidence and/or its contents. Copyright statements are legal notices of intellectual property ownership and may include restrictions on the use and publishing of the Evidencecopyright : markdown [0..1]A short string (<50 characters), suitable for inclusion in a page footer that identifies the copyright holder, effective period, and optionally whether rights are restricted. (e.g. 'All rights reserved', 'Some rights reserved')copyrightLabel : string [0..1]Link or citation to artifact associated with the summaryrelatedArtifact : RelatedArtifact [0..*]A natural language summary of the evidencedescription : markdown [0..1]Declarative description of the Evidence, such as conclusion or bottom line statementassertion : markdown [0..1]Footnotes and/or explanatory notesnote : Annotation [0..*]The design of the synthesis (combination of studies) that produced this evidence. The design is described with any number of synthesis characteristics, such as type of meta-analysissynthesisType : CodeableConcept [0..*] « null (Strength=Extensible)StatisticSynthesisType+ »The design of the study that produced this evidence. The design is described with any number of study design characteristicsstudyDesign : CodeableConcept [0..*] « null (Strength=Extensible)StudyDesign+ »VariableDefinitionA text description or summary of the variabledescription : markdown [0..1]Footnotes and/or explanatory notesnote : Annotation [0..*]Classification of the role of the variablevariableRole : code [1..1] « null (Strength=Required)EvidenceVariableRole! »Sub-classification of the role of the variableroleSubtype : CodeableConcept [0..1] « null (Strength=Extensible)EvidenceVariableRoleSubtype+ »The reference value used for comparisoncomparatorCategory : string [0..1]Definition of the actual variable related to the statistic(s), i.e., the population being the actual study sample or the measured variable (exposure, outcome, or covariate) being the actual observation that occurred or will occur in the studyobserved : Reference [0..1] « Group|EvidenceVariable »Definition of the intended variable related to the Evidence, i.e., the population, exposure, or outcome for which the statistical finding is being interpretedintended : Reference [0..1] « Group|EvidenceVariable »Indication of quality of match between intended variable to actual variabledirectnessMatch : CodeableConcept [0..1] « null (Strength=Extensible)EvidenceDirectness+ »StatisticA natural language summary of the statisticdescription : markdown [0..1]Footnotes and/or explanatory notesnote : Annotation [0..*]Type of statistic, e.g., relative risk. The statistic type is a classification that formally defines the relationship between the variables (noted in Evidence.variableDefinition) and the value specification (noted in Evidence.statistic.quantity)statisticType : CodeableConcept [0..1] « null (Strength=Extensible)StatisticType+ »When the measured variable (outcome) is handled categorically, the category element is used to define which category the statistic is reportingcategory : CodeableConcept [0..1]Statistic valuequantity : Quantity [0..1]The number of events associated with the statistic, where the unit of analysis is different from numberAffected, sampleSize.knownDataCount and sampleSize.numberOfParticipantsnumberOfEvents : unsignedInt [0..1]The number of participants affected where the unit of analysis is the same as sampleSize.knownDataCount and sampleSize.numberOfParticipantsnumberAffected : unsignedInt [0..1]SampleSizeHuman-readable summary of study sample size. A human-readable string to clarify or explain concepts about the sample sizedescription : markdown [0..1]Footnote or explanatory note about the sample sizenote : Annotation [0..*]Count of studies or samples combined to become the total sample for the statisticnumberOfStudies : unsignedInt [0..1]Count of members in the total sample for the statisticnumberOfParticipants : unsignedInt [0..1]Number of participants with known results for measured variablesknownDataCount : unsignedInt [0..1]AttributeEstimateHuman-readable summary of the estimatedescription : markdown [0..1]Footnote or explanatory note about the estimatenote : Annotation [0..*]The type of attribute estimate, e.g., confidence interval or p valuetype : CodeableConcept [0..1] « null (Strength=Extensible)AttributeEstimateType+ »The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measurequantity : Quantity [0..1]Use 0.95 for a 95% confidence intervallevel : decimal [0..1]Lower and upper bound values of the attribute estimaterange : Range [0..1]ModelCharacteristicDescription of a component of the method to generate the statisticcode : CodeableConcept [1..1] « null (Strength=Extensible)StatisticModelCode+ »Further specification of the value of the component of the method to generate the statisticvalue[x] : DataType [0..1] « Quantity(SimpleQuantity)|Range| CodeableConcept »The plan for analysisintended : boolean [0..1]This model characteristic is part of the analysis that was applied, whether or not the analysis followed the planapplied : boolean [0..1]VariableDescription and definition of the variablevariableDefinition : Reference [1..1] « Group|EvidenceVariable »How the variable is classified for use in adjusted analysishandling : code [0..1] « null (Strength=Required)EvidenceVariableHandling! »Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variablevalueCategory : CodeableConcept [0..*]Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variablevalueQuantity : Quantity [0..*]Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variablevalueRange : Range [0..*]CertaintyTextual description of certaintydescription : markdown [0..1]Footnotes and/or explanatory notesnote : Annotation [0..*]Aspect of certainty being ratedtype : CodeableConcept [0..1] « null (Strength=Extensible)EvidenceCertaintyType+ »Assessment or judgement of the aspectrating : CodeableConcept [0..*] « null (Strength=Extensible)EvidenceCertaintyRating+ »Individual or group who did the ratingrater : string [0..1]Description, classification, and definition of a single variable. The collection of variables defines what the evidence is aboutvariableDefinition[0..*]Count of participants in the study samplesampleSize[0..1]A nested attribute estimate; which is the attribute estimate of an attribute estimateattributeEstimate[0..*]A statistical attribute of the statistic such as a measure of heterogeneityattributeEstimate[0..*]A variable adjusted for in the adjusted analysisvariable[0..*]An attribute of the model characteristicattribute[0..*]A component of the method to generate the statisticmodelCharacteristic[0..*]Values and parameters for a single statisticstatistic[0..*]A domain or subdomain of certaintysubcomponent[0..*]Assessment of certainty, confidence in the estimates, or quality of the evidencecertainty[0..*]

XML Template

<Evidence xmlns="http://hl7.org/fhir"> doco
 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <url value="[uri]"/><!-- 0..1 Canonical identifier for this evidence, represented as a globally unique URI -->
 <identifier><!-- 0..* Identifier Additional identifier for the summary --></identifier>
 <version value="[string]"/><!-- 0..1 Business version of this summary -->
 <versionAlgorithm[x]><!-- 0..1 string|Coding How to compare versions --></versionAlgorithm[x]>
 <name value="[string]"/><!-- I 0..1 Name for this summary (machine friendly) -->
 <title value="[string]"/><!-- 0..1 Name for this summary (human friendly) -->
 <citeAs[x]><!-- 0..1 Reference(Citation)|markdown Citation for this evidence --></citeAs[x]>
 <status value="[code]"/><!-- 1..1 draft | active | retired | unknown -->
 <experimental value="[boolean]"/><!-- 0..1 For testing purposes, not real usage -->
 <date value="[dateTime]"/><!-- 0..1 Date last changed -->
 <approvalDate value="[date]"/><!-- 0..1 When the summary was approved by publisher -->
 <lastReviewDate value="[date]"/><!-- 0..1 When the summary was last reviewed by the publisher -->
 <author><!-- 0..* ContactDetail Who authored the content --></author>
 <publisher value="[string]"/><!-- 0..1 Name of the publisher/steward (organization or individual) -->
 <contact><!-- 0..* ContactDetail Contact details for the publisher --></contact>
 <recorder><!-- 0..* ContactDetail Who entered the data for the evidence --></recorder>
 <editor><!-- 0..* ContactDetail Who edited the content --></editor>
 <reviewer><!-- 0..* ContactDetail Who reviewed the content --></reviewer>
 <endorser><!-- 0..* ContactDetail Who endorsed the content --></endorser>
 <useContext><!-- 0..* UsageContext The context that the content is intended to support --></useContext>
 <purpose value="[markdown]"/><!-- 0..1 Why this Evidence is defined -->
 <copyright value="[markdown]"/><!-- 0..1 Intellectual property ownership, may include restrictions on use -->
 <copyrightLabel value="[string]"/><!-- 0..1 Copyright holder and year(s) -->
 <relatedArtifact><!-- 0..* RelatedArtifact Link or citation to artifact associated with the summary --></relatedArtifact>
 <description value="[markdown]"/><!-- 0..1 Description of the particular summary -->
 <assertion value="[markdown]"/><!-- 0..1 Declarative description of the Evidence -->
 <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
 <variableDefinition>  <!-- 0..* Description, classification, and definition of a single variable -->
  <description value="[markdown]"/><!-- 0..1 A text description or summary of the variable -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <variableRole value="[code]"/><!-- 1..1 population | exposure | outcome | covariate -->
  <roleSubtype><!-- 0..1 CodeableConcept Sub-classification of the role of the variable --></roleSubtype>
  <comparatorCategory value="[string]"/><!-- 0..1 The reference value used for comparison -->
  <observed><!-- 0..1 Reference(EvidenceVariable|Group) Definition of the actual variable related to the statistic(s) --></observed>
  <intended><!-- 0..1 Reference(EvidenceVariable|Group) Definition of the intended variable related to the Evidence --></intended>
  <directnessMatch><!-- 0..1 CodeableConcept low | moderate | high | exact icon --></directnessMatch>
 </variableDefinition>
 <synthesisType><!-- 0..* CodeableConcept The design of the synthesis (combination of studies) that produced this evidence icon --></synthesisType>
 <studyDesign><!-- 0..* CodeableConcept The design of the study that produced this evidence --></studyDesign>
 <statistic>  <!-- 0..* Values and parameters for a single statistic -->
  <description value="[markdown]"/><!-- 0..1 A natural language summary of the statistic -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <statisticType><!-- 0..1 CodeableConcept Type of statistic, e.g., relative risk --></statisticType>
  <category><!-- 0..1 CodeableConcept Associated category for categorical variable --></category>
  <quantity><!-- 0..1 Quantity Statistic value --></quantity>
  <numberOfEvents value="[unsignedInt]"/><!-- 0..1 The number of events associated with the statistic -->
  <numberAffected value="[unsignedInt]"/><!-- 0..1 The number of participants affected -->
  <sampleSize>  <!-- 0..1 Count of participants in the study sample -->
   <description value="[markdown]"/><!-- 0..1 Textual description of sample size for statistic -->
   <note><!-- 0..* Annotation Footnote or explanatory note about the sample size --></note>
   <numberOfStudies value="[unsignedInt]"/><!-- 0..1 Number of contributing studies -->
   <numberOfParticipants value="[unsignedInt]"/><!-- 0..1 Total number of participants -->
   <knownDataCount value="[unsignedInt]"/><!-- 0..1 Number of participants with known results for measured variables -->
  </sampleSize>
  <attributeEstimate>  <!-- 0..* An attribute of the Statistic -->
   <description value="[markdown]"/><!-- 0..1 Textual description of the attribute estimate -->
   <note><!-- 0..* Annotation Footnote or explanatory note about the estimate --></note>
   <type><!-- 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value --></type>
   <quantity><!-- 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measure --></quantity>
   <level value="[decimal]"/><!-- 0..1 Level of confidence interval, e.g., 0.95 for 95% confidence interval -->
   <range><!-- 0..1 Range Lower and upper bound values of the attribute estimate --></range>
   <attributeEstimate><!-- 0..* Content as for Evidence.statistic.attributeEstimate A nested attribute estimate; which is the attribute estimate of an attribute estimate --></attributeEstimate>
  </attributeEstimate>
  <modelCharacteristic>  <!-- 0..* An aspect of the statistical model -->
   <code><!-- 1..1 CodeableConcept Model specification --></code>
   <value[x]><!-- 0..1 Quantity(SimpleQuantity)|Range|CodeableConcept The specific value (when paired with code) --></value[x]>
   <intended value="[boolean]"/><!-- 0..1 The plan for analysis -->
   <applied value="[boolean]"/><!-- 0..1 This model characteristic is part of the analysis that was applied, whether or not the analysis followed the plan -->
   <variable>  <!-- 0..* A variable adjusted for in the adjusted analysis -->
    <variableDefinition><!-- 1..1 Reference(EvidenceVariable|Group) Description and definition of the variable --></variableDefinition>
    <handling value="[code]"/><!-- 0..1 continuous | dichotomous | ordinal | polychotomous -->
    <valueCategory><!-- 0..* CodeableConcept Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable --></valueCategory>
    <valueQuantity><!-- 0..* Quantity Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable --></valueQuantity>
    <valueRange><!-- 0..* Range Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variable --></valueRange>
   </variable>
   <attribute><!-- 0..* Content as for Evidence.statistic.attributeEstimate An attribute of the model characteristic --></attribute>
  </modelCharacteristic>
 </statistic>
 <certainty>  <!-- 0..* Certainty or quality of the evidence -->
  <description value="[markdown]"/><!-- 0..1 Textual description of certainty -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <type><!-- 0..1 CodeableConcept Aspect of certainty being rated --></type>
  <rating><!-- 0..* CodeableConcept Assessment or judgement of the aspect --></rating>
  <rater value="[string]"/><!-- 0..1 Individual or group who did the rating -->
  <subcomponent><!-- 0..* Content as for Evidence.certainty A domain or subdomain of certainty --></subcomponent>
 </certainty>
</Evidence>

JSON Template

{doco
  "resourceType" : "Evidence",
  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "url" : "<uri>", // Canonical identifier for this evidence, represented as a globally unique URI
  "identifier" : [{ Identifier }], // Additional identifier for the summary
  "version" : "<string>", // Business version of this summary
  // versionAlgorithm[x]: How to compare versions. One of these 2:
  "versionAlgorithmString" : "<string>",
  "versionAlgorithmCoding" : { Coding },
  "name" : "<string>", // I Name for this summary (machine friendly)
  "title" : "<string>", // Name for this summary (human friendly)
  // citeAs[x]: Citation for this evidence. One of these 2:
  "citeAsReference" : { Reference(Citation) },
  "citeAsMarkdown" : "<markdown>",
  "status" : "<code>", // R!  draft | active | retired | unknown
  "experimental" : <boolean>, // For testing purposes, not real usage
  "date" : "<dateTime>", // Date last changed
  "approvalDate" : "<date>", // When the summary was approved by publisher
  "lastReviewDate" : "<date>", // When the summary was last reviewed by the publisher
  "author" : [{ ContactDetail }], // Who authored the content
  "publisher" : "<string>", // Name of the publisher/steward (organization or individual)
  "contact" : [{ ContactDetail }], // Contact details for the publisher
  "recorder" : [{ ContactDetail }], // Who entered the data for the evidence
  "editor" : [{ ContactDetail }], // Who edited the content
  "reviewer" : [{ ContactDetail }], // Who reviewed the content
  "endorser" : [{ ContactDetail }], // Who endorsed the content
  "useContext" : [{ UsageContext }], // The context that the content is intended to support
  "purpose" : "<markdown>", // Why this Evidence is defined
  "copyright" : "<markdown>", // Intellectual property ownership, may include restrictions on use
  "copyrightLabel" : "<string>", // Copyright holder and year(s)
  "relatedArtifact" : [{ RelatedArtifact }], // Link or citation to artifact associated with the summary
  "description" : "<markdown>", // Description of the particular summary
  "assertion" : "<markdown>", // Declarative description of the Evidence
  "note" : [{ Annotation }], // Footnotes and/or explanatory notes
  "variableDefinition" : [{ // Description, classification, and definition of a single variable
    "description" : "<markdown>", // A text description or summary of the variable
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "variableRole" : "<code>", // R!  population | exposure | outcome | covariate
    "roleSubtype" : { CodeableConcept }, // Sub-classification of the role of the variable
    "comparatorCategory" : "<string>", // The reference value used for comparison
    "observed" : { Reference(EvidenceVariable|Group) }, // Definition of the actual variable related to the statistic(s)
    "intended" : { Reference(EvidenceVariable|Group) }, // Definition of the intended variable related to the Evidence
    "directnessMatch" : { CodeableConcept } // low | moderate | high | exact icon
  }],
  "synthesisType" : [{ CodeableConcept }], // The design of the synthesis (combination of studies) that produced this evidence icon
  "studyDesign" : [{ CodeableConcept }], // The design of the study that produced this evidence
  "statistic" : [{ // Values and parameters for a single statistic
    "description" : "<markdown>", // A natural language summary of the statistic
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "statisticType" : { CodeableConcept }, // Type of statistic, e.g., relative risk
    "category" : { CodeableConcept }, // Associated category for categorical variable
    "quantity" : { Quantity }, // Statistic value
    "numberOfEvents" : "<unsignedInt>", // The number of events associated with the statistic
    "numberAffected" : "<unsignedInt>", // The number of participants affected
    "sampleSize" : { // Count of participants in the study sample
      "description" : "<markdown>", // Textual description of sample size for statistic
      "note" : [{ Annotation }], // Footnote or explanatory note about the sample size
      "numberOfStudies" : "<unsignedInt>", // Number of contributing studies
      "numberOfParticipants" : "<unsignedInt>", // Total number of participants
      "knownDataCount" : "<unsignedInt>" // Number of participants with known results for measured variables
    },
    "attributeEstimate" : [{ // An attribute of the Statistic
      "description" : "<markdown>", // Textual description of the attribute estimate
      "note" : [{ Annotation }], // Footnote or explanatory note about the estimate
      "type" : { CodeableConcept }, // The type of attribute estimate, e.g., confidence interval or p value
      "quantity" : { Quantity }, // The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measure
      "level" : <decimal>, // Level of confidence interval, e.g., 0.95 for 95% confidence interval
      "range" : { Range }, // Lower and upper bound values of the attribute estimate
      "attributeEstimate" : [{ Content as for Evidence.statistic.attributeEstimate }] // A nested attribute estimate; which is the attribute estimate of an attribute estimate
    }],
    "modelCharacteristic" : [{ // An aspect of the statistical model
      "code" : { CodeableConcept }, // R!  Model specification
      // value[x]: The specific value (when paired with code). One of these 3:
      "valueQuantity" : { Quantity(SimpleQuantity) },
      "valueRange" : { Range },
      "valueCodeableConcept" : { CodeableConcept },
      "intended" : <boolean>, // The plan for analysis
      "applied" : <boolean>, // This model characteristic is part of the analysis that was applied, whether or not the analysis followed the plan
      "variable" : [{ // A variable adjusted for in the adjusted analysis
        "variableDefinition" : { Reference(EvidenceVariable|Group) }, // R!  Description and definition of the variable
        "handling" : "<code>", // continuous | dichotomous | ordinal | polychotomous
        "valueCategory" : [{ CodeableConcept }], // Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable
        "valueQuantity" : [{ Quantity }], // Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable
        "valueRange" : [{ Range }] // Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variable
      }],
      "attribute" : [{ Content as for Evidence.statistic.attributeEstimate }] // An attribute of the model characteristic
    }]
  }],
  "certainty" : [{ // Certainty or quality of the evidence
    "description" : "<markdown>", // Textual description of certainty
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "type" : { CodeableConcept }, // Aspect of certainty being rated
    "rating" : [{ CodeableConcept }], // Assessment or judgement of the aspect
    "rater" : "<string>", // Individual or group who did the rating
    "subcomponent" : [{ Content as for Evidence.certainty }] // A domain or subdomain of certainty
  }]
}

Turtle Template

@prefix fhir: <http://hl7.org/fhir/> .doco


[ a fhir:Evidence;
  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:url [ uri ] ; # 0..1 Canonical identifier for this evidence, represented as a globally unique URI
  fhir:identifier  ( [ Identifier ] ... ) ; # 0..* Additional identifier for the summary
  fhir:version [ string ] ; # 0..1 Business version of this summary
  # versionAlgorithm[x] : 0..1 How to compare versions. One of these 2
    fhir:versionAlgorithm [  a fhir:string ; string ]
    fhir:versionAlgorithm [  a fhir:Coding ; Coding ]
  fhir:name [ string ] ; # 0..1 I Name for this summary (machine friendly)
  fhir:title [ string ] ; # 0..1 Name for this summary (human friendly)
  # citeAs[x] : 0..1 Citation for this evidence. One of these 2
    fhir:citeAs [  a fhir:Reference ; Reference(Citation) ]
    fhir:citeAs [  a fhir:markdown ; markdown ]
  fhir:status [ code ] ; # 1..1 draft | active | retired | unknown
  fhir:experimental [ boolean ] ; # 0..1 For testing purposes, not real usage
  fhir:date [ dateTime ] ; # 0..1 Date last changed
  fhir:approvalDate [ date ] ; # 0..1 When the summary was approved by publisher
  fhir:lastReviewDate [ date ] ; # 0..1 When the summary was last reviewed by the publisher
  fhir:author  ( [ ContactDetail ] ... ) ; # 0..* Who authored the content
  fhir:publisher [ string ] ; # 0..1 Name of the publisher/steward (organization or individual)
  fhir:contact  ( [ ContactDetail ] ... ) ; # 0..* Contact details for the publisher
  fhir:recorder  ( [ ContactDetail ] ... ) ; # 0..* Who entered the data for the evidence
  fhir:editor  ( [ ContactDetail ] ... ) ; # 0..* Who edited the content
  fhir:reviewer  ( [ ContactDetail ] ... ) ; # 0..* Who reviewed the content
  fhir:endorser  ( [ ContactDetail ] ... ) ; # 0..* Who endorsed the content
  fhir:useContext  ( [ UsageContext ] ... ) ; # 0..* The context that the content is intended to support
  fhir:purpose [ markdown ] ; # 0..1 Why this Evidence is defined
  fhir:copyright [ markdown ] ; # 0..1 Intellectual property ownership, may include restrictions on use
  fhir:copyrightLabel [ string ] ; # 0..1 Copyright holder and year(s)
  fhir:relatedArtifact  ( [ RelatedArtifact ] ... ) ; # 0..* Link or citation to artifact associated with the summary
  fhir:description [ markdown ] ; # 0..1 Description of the particular summary
  fhir:assertion [ markdown ] ; # 0..1 Declarative description of the Evidence
  fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnotes and/or explanatory notes
  fhir:variableDefinition ( [ # 0..* Description, classification, and definition of a single variable
    fhir:description [ markdown ] ; # 0..1 A text description or summary of the variable
    fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnotes and/or explanatory notes
    fhir:variableRole [ code ] ; # 1..1 population | exposure | outcome | covariate
    fhir:roleSubtype [ CodeableConcept ] ; # 0..1 Sub-classification of the role of the variable
    fhir:comparatorCategory [ string ] ; # 0..1 The reference value used for comparison
    fhir:observed [ Reference(EvidenceVariable|Group) ] ; # 0..1 Definition of the actual variable related to the statistic(s)
    fhir:intended [ Reference(EvidenceVariable|Group) ] ; # 0..1 Definition of the intended variable related to the Evidence
    fhir:directnessMatch [ CodeableConcept ] ; # 0..1 low | moderate | high | exact
  ] ... ) ;
  fhir:synthesisType  ( [ CodeableConcept ] ... ) ; # 0..* The design of the synthesis (combination of studies) that produced this evidence
  fhir:studyDesign  ( [ CodeableConcept ] ... ) ; # 0..* The design of the study that produced this evidence
  fhir:statistic ( [ # 0..* Values and parameters for a single statistic
    fhir:description [ markdown ] ; # 0..1 A natural language summary of the statistic
    fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnotes and/or explanatory notes
    fhir:statisticType [ CodeableConcept ] ; # 0..1 Type of statistic, e.g., relative risk
    fhir:category [ CodeableConcept ] ; # 0..1 Associated category for categorical variable
    fhir:quantity [ Quantity ] ; # 0..1 Statistic value
    fhir:numberOfEvents [ unsignedInt ] ; # 0..1 The number of events associated with the statistic
    fhir:numberAffected [ unsignedInt ] ; # 0..1 The number of participants affected
    fhir:sampleSize [ # 0..1 Count of participants in the study sample
      fhir:description [ markdown ] ; # 0..1 Textual description of sample size for statistic
      fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnote or explanatory note about the sample size
      fhir:numberOfStudies [ unsignedInt ] ; # 0..1 Number of contributing studies
      fhir:numberOfParticipants [ unsignedInt ] ; # 0..1 Total number of participants
      fhir:knownDataCount [ unsignedInt ] ; # 0..1 Number of participants with known results for measured variables
    ] ;
    fhir:attributeEstimate ( [ # 0..* An attribute of the Statistic
      fhir:description [ markdown ] ; # 0..1 Textual description of the attribute estimate
      fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnote or explanatory note about the estimate
      fhir:type [ CodeableConcept ] ; # 0..1 The type of attribute estimate, e.g., confidence interval or p value
      fhir:quantity [ Quantity ] ; # 0..1 The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measure
      fhir:level [ decimal ] ; # 0..1 Level of confidence interval, e.g., 0.95 for 95% confidence interval
      fhir:range [ Range ] ; # 0..1 Lower and upper bound values of the attribute estimate
      fhir:attributeEstimate  ( [ See Evidence.statistic.attributeEstimate ] ... ) ; # 0..* A nested attribute estimate; which is the attribute estimate of an attribute estimate
    ] ... ) ;
    fhir:modelCharacteristic ( [ # 0..* An aspect of the statistical model
      fhir:code [ CodeableConcept ] ; # 1..1 Model specification
      # value[x] : 0..1 The specific value (when paired with code). One of these 3
        fhir:value [  a fhir:SimpleQuantity ; Quantity(SimpleQuantity) ]
        fhir:value [  a fhir:Range ; Range ]
        fhir:value [  a fhir:CodeableConcept ; CodeableConcept ]
      fhir:intended [ boolean ] ; # 0..1 The plan for analysis
      fhir:applied [ boolean ] ; # 0..1 This model characteristic is part of the analysis that was applied, whether or not the analysis followed the plan
      fhir:variable ( [ # 0..* A variable adjusted for in the adjusted analysis
        fhir:variableDefinition [ Reference(EvidenceVariable|Group) ] ; # 1..1 Description and definition of the variable
        fhir:handling [ code ] ; # 0..1 continuous | dichotomous | ordinal | polychotomous
        fhir:valueCategory  ( [ CodeableConcept ] ... ) ; # 0..* Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable
        fhir:valueQuantity  ( [ Quantity ] ... ) ; # 0..* Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable
        fhir:valueRange  ( [ Range ] ... ) ; # 0..* Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variable
      ] ... ) ;
      fhir:attribute  ( [ See Evidence.statistic.attributeEstimate ] ... ) ; # 0..* An attribute of the model characteristic
    ] ... ) ;
  ] ... ) ;
  fhir:certainty ( [ # 0..* Certainty or quality of the evidence
    fhir:description [ markdown ] ; # 0..1 Textual description of certainty
    fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnotes and/or explanatory notes
    fhir:type [ CodeableConcept ] ; # 0..1 Aspect of certainty being rated
    fhir:rating  ( [ CodeableConcept ] ... ) ; # 0..* Assessment or judgement of the aspect
    fhir:rater [ string ] ; # 0..1 Individual or group who did the rating
    fhir:subcomponent  ( [ See Evidence.certainty ] ... ) ; # 0..* A domain or subdomain of certainty
  ] ... ) ;
]

Changes from both R4 and R4B

Evidence
Evidence.versionAlgorithm[x]
  • Added Element
Evidence.citeAs[x]
  • Added Element
Evidence.experimental
  • Added Element
Evidence.recorder
  • Added Element
Evidence.purpose
  • Added Element
Evidence.copyrightLabel
  • Added Element
Evidence.assertion
  • Added Element
Evidence.variableDefinition
  • Added Element
Evidence.variableDefinition.description
  • Added Element
Evidence.variableDefinition.note
  • Added Element
Evidence.variableDefinition.variableRole
  • Added Mandatory Element
Evidence.variableDefinition.roleSubtype
  • Added Element
Evidence.variableDefinition.comparatorCategory
  • Added Element
Evidence.variableDefinition.observed
  • Added Element
Evidence.variableDefinition.intended
  • Added Element
Evidence.variableDefinition.directnessMatch
  • Added Element
Evidence.synthesisType
  • Added Element
Evidence.studyDesign
  • Added Element
Evidence.statistic
  • Added Element
Evidence.statistic.description
  • Added Element
Evidence.statistic.note
  • Added Element
Evidence.statistic.statisticType
  • Added Element
Evidence.statistic.category
  • Added Element
Evidence.statistic.quantity
  • Added Element
Evidence.statistic.numberOfEvents
  • Added Element
Evidence.statistic.numberAffected
  • Added Element
Evidence.statistic.sampleSize
  • Added Element
Evidence.statistic.sampleSize.description
  • Added Element
Evidence.statistic.sampleSize.note
  • Added Element
Evidence.statistic.sampleSize.numberOfStudies
  • Added Element
Evidence.statistic.sampleSize.numberOfParticipants
  • Added Element
Evidence.statistic.sampleSize.knownDataCount
  • Added Element
Evidence.statistic.attributeEstimate
  • Added Element
Evidence.statistic.attributeEstimate.description
  • Added Element
Evidence.statistic.attributeEstimate.note
  • Added Element
Evidence.statistic.attributeEstimate.type
  • Added Element
Evidence.statistic.attributeEstimate.quantity
  • Added Element
Evidence.statistic.attributeEstimate.level
  • Added Element
Evidence.statistic.attributeEstimate.range
  • Added Element
Evidence.statistic.attributeEstimate.attributeEstimate
  • Added Element
Evidence.statistic.modelCharacteristic
  • Added Element
Evidence.statistic.modelCharacteristic.code
  • Added Mandatory Element
Evidence.statistic.modelCharacteristic.value[x]
  • Added Element
Evidence.statistic.modelCharacteristic.intended
  • Added Element
Evidence.statistic.modelCharacteristic.applied
  • Added Element
Evidence.statistic.modelCharacteristic.variable
  • Added Element
Evidence.statistic.modelCharacteristic.variable.variableDefinition
  • Added Mandatory Element
Evidence.statistic.modelCharacteristic.variable.handling
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueCategory
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueQuantity
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueRange
  • Added Element
Evidence.statistic.modelCharacteristic.attribute
  • Added Element
Evidence.certainty
  • Added Element
Evidence.certainty.description
  • Added Element
Evidence.certainty.note
  • Added Element
Evidence.certainty.type
  • Added Element
Evidence.certainty.rating
  • Added Element
Evidence.certainty.rater
  • Added Element
Evidence.certainty.subcomponent
  • Added Element
Evidence.shortTitle
  • Deleted
Evidence.subtitle
  • Deleted
Evidence.jurisdiction
  • Deleted
Evidence.effectivePeriod
  • Deleted
Evidence.topic
  • Deleted
Evidence.exposureBackground
  • Deleted
Evidence.exposureVariant
  • Deleted
Evidence.outcome
  • Deleted

See the Full Difference for further information

This analysis is available for R4 as XML or JSON and for R4B as XML or JSON.

Structure

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence TU DomainResource Single evidence bit
+ Warning: Name should be usable as an identifier for the module by machine processing applications such as code generation

Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension
Interfaces Implemented: MetadataResource
... url ΣC 0..1 uri Canonical identifier for this evidence, represented as a globally unique URI
+ Warning: URL should not contain | or # - these characters make processing canonical references problematic
... identifier Σ 0..* Identifier Additional identifier for the summary

... version Σ 0..1 string Business version of this summary
... versionAlgorithm[x] Σ 0..1 How to compare versions
Binding: Version Algorithm (Extensible)
.... versionAlgorithmString string
.... versionAlgorithmCoding Coding
... name C 0..1 string Name for this summary (machine friendly)
... title ΣT 0..1 string Name for this summary (human friendly)
... citeAs[x] 0..1 Citation for this evidence
.... citeAsReference Reference(Citation)
.... citeAsMarkdown markdown
... status ?!Σ 1..1 code draft | active | retired | unknown
Binding: PublicationStatus (Required)
... experimental 0..1 boolean For testing purposes, not real usage
... date Σ 0..1 dateTime Date last changed
... approvalDate 0..1 date When the summary was approved by publisher
... lastReviewDate 0..1 date When the summary was last reviewed by the publisher
... author Σ 0..* ContactDetail Who authored the content

... publisher ΣT 0..1 string Name of the publisher/steward (organization or individual)
... contact Σ 0..* ContactDetail Contact details for the publisher

... recorder 0..* ContactDetail Who entered the data for the evidence

... editor 0..* ContactDetail Who edited the content

... reviewer 0..* ContactDetail Who reviewed the content

... endorser 0..* ContactDetail Who endorsed the content

... useContext Σ 0..* UsageContext The context that the content is intended to support

... purpose 0..1 markdown Why this Evidence is defined
... copyright 0..1 markdown Intellectual property ownership, may include restrictions on use
... copyrightLabel T 0..1 string Copyright holder and year(s)
... relatedArtifact 0..* RelatedArtifact Link or citation to artifact associated with the summary

... description ΣT 0..1 markdown Description of the particular summary
... assertion T 0..1 markdown Declarative description of the Evidence
... note 0..* Annotation Footnotes and/or explanatory notes

... variableDefinition 0..* BackboneElement Description, classification, and definition of a single variable

.... description 0..1 markdown A text description or summary of the variable
.... note 0..* Annotation Footnotes and/or explanatory notes

.... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: Evidence Variable Role (Required)
.... roleSubtype 0..1 CodeableConcept Sub-classification of the role of the variable
Binding: Evidence Variable Role Subtype (Extensible)
.... comparatorCategory 0..1 string The reference value used for comparison
.... observed Σ 0..1 Reference(Group | EvidenceVariable) Definition of the actual variable related to the statistic(s)
.... intended 0..1 Reference(Group | EvidenceVariable) Definition of the intended variable related to the Evidence
.... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
Binding: EvidenceDirectness icon (Extensible)
... synthesisType 0..* CodeableConcept The design of the synthesis (combination of studies) that produced this evidence
Binding: StatisticSynthesisType icon (Extensible)

... studyDesign 0..* CodeableConcept The design of the study that produced this evidence
Binding: Study Design (Extensible)

... statistic 0..* BackboneElement Values and parameters for a single statistic

.... description 0..1 markdown A natural language summary of the statistic
.... note 0..* Annotation Footnotes and/or explanatory notes

.... statisticType Σ 0..1 CodeableConcept Type of statistic, e.g., relative risk
Binding: Statistic Type (Extensible)
.... category 0..1 CodeableConcept Associated category for categorical variable
.... quantity Σ 0..1 Quantity Statistic value
.... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
.... numberAffected 0..1 unsignedInt The number of participants affected
.... sampleSize 0..1 BackboneElement Count of participants in the study sample
..... description 0..1 markdown Textual description of sample size for statistic
..... note 0..* Annotation Footnote or explanatory note about the sample size

..... numberOfStudies 0..1 unsignedInt Number of contributing studies
..... numberOfParticipants 0..1 unsignedInt Total number of participants
..... knownDataCount 0..1 unsignedInt Number of participants with known results for measured variables
.... attributeEstimate 0..* BackboneElement An attribute of the Statistic

..... description 0..1 markdown Textual description of the attribute estimate
..... note 0..* Annotation Footnote or explanatory note about the estimate

..... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: Attribute Estimate Type (Extensible)
..... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measure
..... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
..... range 0..1 Range Lower and upper bound values of the attribute estimate
..... attributeEstimate 0..* see attributeEstimate A nested attribute estimate; which is the attribute estimate of an attribute estimate

.... modelCharacteristic 0..* BackboneElement An aspect of the statistical model

..... code 1..1 CodeableConcept Model specification
Binding: Statistic Model Code (Extensible)
..... value[x] 0..1 The specific value (when paired with code)
...... valueQuantity SimpleQuantity
...... valueRange Range
...... valueCodeableConcept CodeableConcept
..... intended 0..1 boolean The plan for analysis
..... applied 0..1 boolean This model characteristic is part of the analysis that was applied, whether or not the analysis followed the plan
..... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis

...... variableDefinition 1..1 Reference(Group | EvidenceVariable) Description and definition of the variable
...... handling 0..1 code continuous | dichotomous | ordinal | polychotomous
Binding: Evidence Variable Handling (Required)
...... valueCategory 0..* CodeableConcept Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable

...... valueQuantity 0..* Quantity Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable

...... valueRange 0..* Range Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variable

..... attribute 0..* see attributeEstimate An attribute of the model characteristic

... certainty 0..* BackboneElement Certainty or quality of the evidence

.... description 0..1 markdown Textual description of certainty
.... note 0..* Annotation Footnotes and/or explanatory notes

.... type 0..1 CodeableConcept Aspect of certainty being rated
Binding: Evidence Certainty Type (Extensible)
.... rating 0..* CodeableConcept Assessment or judgement of the aspect
Binding: Evidence Certainty Rating (Extensible)

.... rater 0..1 string Individual or group who did the rating
.... subcomponent 0..* see certainty A domain or subdomain of certainty


doco Documentation for this format icon

See the Extensions for this resource

UML Diagram (Legend)

Evidence (DomainResource) +MetadataResourceAn absolute URI that is used to identify this evidence when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which an authoritative instance of this summary is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the summary is stored on different serversurl : uri [0..1]A formal identifier that is used to identify this summary when it is represented in other formats, or referenced in a specification, model, design or an instanceidentifier : Identifier [0..*]The identifier that is used to identify this version of the summary when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the summary author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequenceversion : string [0..1]Indicates the mechanism used to compare versions to determine which is more currentversionAlgorithm[x] : DataType [0..1] « string|Coding; null (Strength=Extensible) VersionAlgorithm+ »A natural language name identifying the evidence. This name should be usable as an identifier for the module by machine processing applications such as code generationname : string [0..1] « This element has or is affected by some invariantsC »A short, descriptive, user-friendly title for the summarytitle : string [0..1]Citation Resource or display of suggested citation for this evidenceciteAs[x] : DataType [0..1] « Reference(Citation)|markdown »The status of this summary. Enables tracking the life-cycle of the content (this element modifies the meaning of other elements)status : code [1..1] « null (Strength=Required)PublicationStatus! »A Boolean value to indicate that this resource is authored for testing purposes (or education/evaluation/marketing) and is not intended to be used for genuine usageexperimental : boolean [0..1]The date (and optionally time) when the summary was last significantly changed. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the summary changesdate : dateTime [0..1]The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usageapprovalDate : date [0..1]The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval datelastReviewDate : date [0..1]An individiual, organization, or device primarily involved in the creation and maintenance of the contentauthor : ContactDetail [0..*]The name of the organization or individual responsible for the release and ongoing maintenance of the evidencepublisher : string [0..1]Contact details to assist a user in finding and communicating with the publishercontact : ContactDetail [0..*]Who entered the data for the evidencerecorder : ContactDetail [0..*]An individiual, organization, or device primarily responsible for internal coherence of the contenteditor : ContactDetail [0..*]An individiual, organization, or device primarily responsible for review of some aspect of the contentreviewer : ContactDetail [0..*]An individiual, organization, or device responsible for officially endorsing the content for use in some settingendorser : ContactDetail [0..*]The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate evidence instancesuseContext : UsageContext [0..*]Explanation of why this Evidence is needed and why it has been designed as it haspurpose : markdown [0..1]A copyright statement relating to the Evidence and/or its contents. Copyright statements are legal notices of intellectual property ownership and may include restrictions on the use and publishing of the Evidencecopyright : markdown [0..1]A short string (<50 characters), suitable for inclusion in a page footer that identifies the copyright holder, effective period, and optionally whether rights are restricted. (e.g. 'All rights reserved', 'Some rights reserved')copyrightLabel : string [0..1]Link or citation to artifact associated with the summaryrelatedArtifact : RelatedArtifact [0..*]A natural language summary of the evidencedescription : markdown [0..1]Declarative description of the Evidence, such as conclusion or bottom line statementassertion : markdown [0..1]Footnotes and/or explanatory notesnote : Annotation [0..*]The design of the synthesis (combination of studies) that produced this evidence. The design is described with any number of synthesis characteristics, such as type of meta-analysissynthesisType : CodeableConcept [0..*] « null (Strength=Extensible)StatisticSynthesisType+ »The design of the study that produced this evidence. The design is described with any number of study design characteristicsstudyDesign : CodeableConcept [0..*] « null (Strength=Extensible)StudyDesign+ »VariableDefinitionA text description or summary of the variabledescription : markdown [0..1]Footnotes and/or explanatory notesnote : Annotation [0..*]Classification of the role of the variablevariableRole : code [1..1] « null (Strength=Required)EvidenceVariableRole! »Sub-classification of the role of the variableroleSubtype : CodeableConcept [0..1] « null (Strength=Extensible)EvidenceVariableRoleSubtype+ »The reference value used for comparisoncomparatorCategory : string [0..1]Definition of the actual variable related to the statistic(s), i.e., the population being the actual study sample or the measured variable (exposure, outcome, or covariate) being the actual observation that occurred or will occur in the studyobserved : Reference [0..1] « Group|EvidenceVariable »Definition of the intended variable related to the Evidence, i.e., the population, exposure, or outcome for which the statistical finding is being interpretedintended : Reference [0..1] « Group|EvidenceVariable »Indication of quality of match between intended variable to actual variabledirectnessMatch : CodeableConcept [0..1] « null (Strength=Extensible)EvidenceDirectness+ »StatisticA natural language summary of the statisticdescription : markdown [0..1]Footnotes and/or explanatory notesnote : Annotation [0..*]Type of statistic, e.g., relative risk. The statistic type is a classification that formally defines the relationship between the variables (noted in Evidence.variableDefinition) and the value specification (noted in Evidence.statistic.quantity)statisticType : CodeableConcept [0..1] « null (Strength=Extensible)StatisticType+ »When the measured variable (outcome) is handled categorically, the category element is used to define which category the statistic is reportingcategory : CodeableConcept [0..1]Statistic valuequantity : Quantity [0..1]The number of events associated with the statistic, where the unit of analysis is different from numberAffected, sampleSize.knownDataCount and sampleSize.numberOfParticipantsnumberOfEvents : unsignedInt [0..1]The number of participants affected where the unit of analysis is the same as sampleSize.knownDataCount and sampleSize.numberOfParticipantsnumberAffected : unsignedInt [0..1]SampleSizeHuman-readable summary of study sample size. A human-readable string to clarify or explain concepts about the sample sizedescription : markdown [0..1]Footnote or explanatory note about the sample sizenote : Annotation [0..*]Count of studies or samples combined to become the total sample for the statisticnumberOfStudies : unsignedInt [0..1]Count of members in the total sample for the statisticnumberOfParticipants : unsignedInt [0..1]Number of participants with known results for measured variablesknownDataCount : unsignedInt [0..1]AttributeEstimateHuman-readable summary of the estimatedescription : markdown [0..1]Footnote or explanatory note about the estimatenote : Annotation [0..*]The type of attribute estimate, e.g., confidence interval or p valuetype : CodeableConcept [0..1] « null (Strength=Extensible)AttributeEstimateType+ »The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measurequantity : Quantity [0..1]Use 0.95 for a 95% confidence intervallevel : decimal [0..1]Lower and upper bound values of the attribute estimaterange : Range [0..1]ModelCharacteristicDescription of a component of the method to generate the statisticcode : CodeableConcept [1..1] « null (Strength=Extensible)StatisticModelCode+ »Further specification of the value of the component of the method to generate the statisticvalue[x] : DataType [0..1] « Quantity(SimpleQuantity)|Range| CodeableConcept »The plan for analysisintended : boolean [0..1]This model characteristic is part of the analysis that was applied, whether or not the analysis followed the planapplied : boolean [0..1]VariableDescription and definition of the variablevariableDefinition : Reference [1..1] « Group|EvidenceVariable »How the variable is classified for use in adjusted analysishandling : code [0..1] « null (Strength=Required)EvidenceVariableHandling! »Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variablevalueCategory : CodeableConcept [0..*]Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variablevalueQuantity : Quantity [0..*]Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variablevalueRange : Range [0..*]CertaintyTextual description of certaintydescription : markdown [0..1]Footnotes and/or explanatory notesnote : Annotation [0..*]Aspect of certainty being ratedtype : CodeableConcept [0..1] « null (Strength=Extensible)EvidenceCertaintyType+ »Assessment or judgement of the aspectrating : CodeableConcept [0..*] « null (Strength=Extensible)EvidenceCertaintyRating+ »Individual or group who did the ratingrater : string [0..1]Description, classification, and definition of a single variable. The collection of variables defines what the evidence is aboutvariableDefinition[0..*]Count of participants in the study samplesampleSize[0..1]A nested attribute estimate; which is the attribute estimate of an attribute estimateattributeEstimate[0..*]A statistical attribute of the statistic such as a measure of heterogeneityattributeEstimate[0..*]A variable adjusted for in the adjusted analysisvariable[0..*]An attribute of the model characteristicattribute[0..*]A component of the method to generate the statisticmodelCharacteristic[0..*]Values and parameters for a single statisticstatistic[0..*]A domain or subdomain of certaintysubcomponent[0..*]Assessment of certainty, confidence in the estimates, or quality of the evidencecertainty[0..*]

XML Template

<Evidence xmlns="http://hl7.org/fhir"> doco
 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <url value="[uri]"/><!-- 0..1 Canonical identifier for this evidence, represented as a globally unique URI -->
 <identifier><!-- 0..* Identifier Additional identifier for the summary --></identifier>
 <version value="[string]"/><!-- 0..1 Business version of this summary -->
 <versionAlgorithm[x]><!-- 0..1 string|Coding How to compare versions --></versionAlgorithm[x]>
 <name value="[string]"/><!-- I 0..1 Name for this summary (machine friendly) -->
 <title value="[string]"/><!-- 0..1 Name for this summary (human friendly) -->
 <citeAs[x]><!-- 0..1 Reference(Citation)|markdown Citation for this evidence --></citeAs[x]>
 <status value="[code]"/><!-- 1..1 draft | active | retired | unknown -->
 <experimental value="[boolean]"/><!-- 0..1 For testing purposes, not real usage -->
 <date value="[dateTime]"/><!-- 0..1 Date last changed -->
 <approvalDate value="[date]"/><!-- 0..1 When the summary was approved by publisher -->
 <lastReviewDate value="[date]"/><!-- 0..1 When the summary was last reviewed by the publisher -->
 <author><!-- 0..* ContactDetail Who authored the content --></author>
 <publisher value="[string]"/><!-- 0..1 Name of the publisher/steward (organization or individual) -->
 <contact><!-- 0..* ContactDetail Contact details for the publisher --></contact>
 <recorder><!-- 0..* ContactDetail Who entered the data for the evidence --></recorder>
 <editor><!-- 0..* ContactDetail Who edited the content --></editor>
 <reviewer><!-- 0..* ContactDetail Who reviewed the content --></reviewer>
 <endorser><!-- 0..* ContactDetail Who endorsed the content --></endorser>
 <useContext><!-- 0..* UsageContext The context that the content is intended to support --></useContext>
 <purpose value="[markdown]"/><!-- 0..1 Why this Evidence is defined -->
 <copyright value="[markdown]"/><!-- 0..1 Intellectual property ownership, may include restrictions on use -->
 <copyrightLabel value="[string]"/><!-- 0..1 Copyright holder and year(s) -->
 <relatedArtifact><!-- 0..* RelatedArtifact Link or citation to artifact associated with the summary --></relatedArtifact>
 <description value="[markdown]"/><!-- 0..1 Description of the particular summary -->
 <assertion value="[markdown]"/><!-- 0..1 Declarative description of the Evidence -->
 <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
 <variableDefinition>  <!-- 0..* Description, classification, and definition of a single variable -->
  <description value="[markdown]"/><!-- 0..1 A text description or summary of the variable -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <variableRole value="[code]"/><!-- 1..1 population | exposure | outcome | covariate -->
  <roleSubtype><!-- 0..1 CodeableConcept Sub-classification of the role of the variable --></roleSubtype>
  <comparatorCategory value="[string]"/><!-- 0..1 The reference value used for comparison -->
  <observed><!-- 0..1 Reference(EvidenceVariable|Group) Definition of the actual variable related to the statistic(s) --></observed>
  <intended><!-- 0..1 Reference(EvidenceVariable|Group) Definition of the intended variable related to the Evidence --></intended>
  <directnessMatch><!-- 0..1 CodeableConcept low | moderate | high | exact icon --></directnessMatch>
 </variableDefinition>
 <synthesisType><!-- 0..* CodeableConcept The design of the synthesis (combination of studies) that produced this evidence icon --></synthesisType>
 <studyDesign><!-- 0..* CodeableConcept The design of the study that produced this evidence --></studyDesign>
 <statistic>  <!-- 0..* Values and parameters for a single statistic -->
  <description value="[markdown]"/><!-- 0..1 A natural language summary of the statistic -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <statisticType><!-- 0..1 CodeableConcept Type of statistic, e.g., relative risk --></statisticType>
  <category><!-- 0..1 CodeableConcept Associated category for categorical variable --></category>
  <quantity><!-- 0..1 Quantity Statistic value --></quantity>
  <numberOfEvents value="[unsignedInt]"/><!-- 0..1 The number of events associated with the statistic -->
  <numberAffected value="[unsignedInt]"/><!-- 0..1 The number of participants affected -->
  <sampleSize>  <!-- 0..1 Count of participants in the study sample -->
   <description value="[markdown]"/><!-- 0..1 Textual description of sample size for statistic -->
   <note><!-- 0..* Annotation Footnote or explanatory note about the sample size --></note>
   <numberOfStudies value="[unsignedInt]"/><!-- 0..1 Number of contributing studies -->
   <numberOfParticipants value="[unsignedInt]"/><!-- 0..1 Total number of participants -->
   <knownDataCount value="[unsignedInt]"/><!-- 0..1 Number of participants with known results for measured variables -->
  </sampleSize>
  <attributeEstimate>  <!-- 0..* An attribute of the Statistic -->
   <description value="[markdown]"/><!-- 0..1 Textual description of the attribute estimate -->
   <note><!-- 0..* Annotation Footnote or explanatory note about the estimate --></note>
   <type><!-- 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value --></type>
   <quantity><!-- 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measure --></quantity>
   <level value="[decimal]"/><!-- 0..1 Level of confidence interval, e.g., 0.95 for 95% confidence interval -->
   <range><!-- 0..1 Range Lower and upper bound values of the attribute estimate --></range>
   <attributeEstimate><!-- 0..* Content as for Evidence.statistic.attributeEstimate A nested attribute estimate; which is the attribute estimate of an attribute estimate --></attributeEstimate>
  </attributeEstimate>
  <modelCharacteristic>  <!-- 0..* An aspect of the statistical model -->
   <code><!-- 1..1 CodeableConcept Model specification --></code>
   <value[x]><!-- 0..1 Quantity(SimpleQuantity)|Range|CodeableConcept The specific value (when paired with code) --></value[x]>
   <intended value="[boolean]"/><!-- 0..1 The plan for analysis -->
   <applied value="[boolean]"/><!-- 0..1 This model characteristic is part of the analysis that was applied, whether or not the analysis followed the plan -->
   <variable>  <!-- 0..* A variable adjusted for in the adjusted analysis -->
    <variableDefinition><!-- 1..1 Reference(EvidenceVariable|Group) Description and definition of the variable --></variableDefinition>
    <handling value="[code]"/><!-- 0..1 continuous | dichotomous | ordinal | polychotomous -->
    <valueCategory><!-- 0..* CodeableConcept Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable --></valueCategory>
    <valueQuantity><!-- 0..* Quantity Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable --></valueQuantity>
    <valueRange><!-- 0..* Range Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variable --></valueRange>
   </variable>
   <attribute><!-- 0..* Content as for Evidence.statistic.attributeEstimate An attribute of the model characteristic --></attribute>
  </modelCharacteristic>
 </statistic>
 <certainty>  <!-- 0..* Certainty or quality of the evidence -->
  <description value="[markdown]"/><!-- 0..1 Textual description of certainty -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <type><!-- 0..1 CodeableConcept Aspect of certainty being rated --></type>
  <rating><!-- 0..* CodeableConcept Assessment or judgement of the aspect --></rating>
  <rater value="[string]"/><!-- 0..1 Individual or group who did the rating -->
  <subcomponent><!-- 0..* Content as for Evidence.certainty A domain or subdomain of certainty --></subcomponent>
 </certainty>
</Evidence>

JSON Template

{doco
  "resourceType" : "Evidence",
  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "url" : "<uri>", // Canonical identifier for this evidence, represented as a globally unique URI
  "identifier" : [{ Identifier }], // Additional identifier for the summary
  "version" : "<string>", // Business version of this summary
  // versionAlgorithm[x]: How to compare versions. One of these 2:
  "versionAlgorithmString" : "<string>",
  "versionAlgorithmCoding" : { Coding },
  "name" : "<string>", // I Name for this summary (machine friendly)
  "title" : "<string>", // Name for this summary (human friendly)
  // citeAs[x]: Citation for this evidence. One of these 2:
  "citeAsReference" : { Reference(Citation) },
  "citeAsMarkdown" : "<markdown>",
  "status" : "<code>", // R!  draft | active | retired | unknown
  "experimental" : <boolean>, // For testing purposes, not real usage
  "date" : "<dateTime>", // Date last changed
  "approvalDate" : "<date>", // When the summary was approved by publisher
  "lastReviewDate" : "<date>", // When the summary was last reviewed by the publisher
  "author" : [{ ContactDetail }], // Who authored the content
  "publisher" : "<string>", // Name of the publisher/steward (organization or individual)
  "contact" : [{ ContactDetail }], // Contact details for the publisher
  "recorder" : [{ ContactDetail }], // Who entered the data for the evidence
  "editor" : [{ ContactDetail }], // Who edited the content
  "reviewer" : [{ ContactDetail }], // Who reviewed the content
  "endorser" : [{ ContactDetail }], // Who endorsed the content
  "useContext" : [{ UsageContext }], // The context that the content is intended to support
  "purpose" : "<markdown>", // Why this Evidence is defined
  "copyright" : "<markdown>", // Intellectual property ownership, may include restrictions on use
  "copyrightLabel" : "<string>", // Copyright holder and year(s)
  "relatedArtifact" : [{ RelatedArtifact }], // Link or citation to artifact associated with the summary
  "description" : "<markdown>", // Description of the particular summary
  "assertion" : "<markdown>", // Declarative description of the Evidence
  "note" : [{ Annotation }], // Footnotes and/or explanatory notes
  "variableDefinition" : [{ // Description, classification, and definition of a single variable
    "description" : "<markdown>", // A text description or summary of the variable
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "variableRole" : "<code>", // R!  population | exposure | outcome | covariate
    "roleSubtype" : { CodeableConcept }, // Sub-classification of the role of the variable
    "comparatorCategory" : "<string>", // The reference value used for comparison
    "observed" : { Reference(EvidenceVariable|Group) }, // Definition of the actual variable related to the statistic(s)
    "intended" : { Reference(EvidenceVariable|Group) }, // Definition of the intended variable related to the Evidence
    "directnessMatch" : { CodeableConcept } // low | moderate | high | exact icon
  }],
  "synthesisType" : [{ CodeableConcept }], // The design of the synthesis (combination of studies) that produced this evidence icon
  "studyDesign" : [{ CodeableConcept }], // The design of the study that produced this evidence
  "statistic" : [{ // Values and parameters for a single statistic
    "description" : "<markdown>", // A natural language summary of the statistic
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "statisticType" : { CodeableConcept }, // Type of statistic, e.g., relative risk
    "category" : { CodeableConcept }, // Associated category for categorical variable
    "quantity" : { Quantity }, // Statistic value
    "numberOfEvents" : "<unsignedInt>", // The number of events associated with the statistic
    "numberAffected" : "<unsignedInt>", // The number of participants affected
    "sampleSize" : { // Count of participants in the study sample
      "description" : "<markdown>", // Textual description of sample size for statistic
      "note" : [{ Annotation }], // Footnote or explanatory note about the sample size
      "numberOfStudies" : "<unsignedInt>", // Number of contributing studies
      "numberOfParticipants" : "<unsignedInt>", // Total number of participants
      "knownDataCount" : "<unsignedInt>" // Number of participants with known results for measured variables
    },
    "attributeEstimate" : [{ // An attribute of the Statistic
      "description" : "<markdown>", // Textual description of the attribute estimate
      "note" : [{ Annotation }], // Footnote or explanatory note about the estimate
      "type" : { CodeableConcept }, // The type of attribute estimate, e.g., confidence interval or p value
      "quantity" : { Quantity }, // The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measure
      "level" : <decimal>, // Level of confidence interval, e.g., 0.95 for 95% confidence interval
      "range" : { Range }, // Lower and upper bound values of the attribute estimate
      "attributeEstimate" : [{ Content as for Evidence.statistic.attributeEstimate }] // A nested attribute estimate; which is the attribute estimate of an attribute estimate
    }],
    "modelCharacteristic" : [{ // An aspect of the statistical model
      "code" : { CodeableConcept }, // R!  Model specification
      // value[x]: The specific value (when paired with code). One of these 3:
      "valueQuantity" : { Quantity(SimpleQuantity) },
      "valueRange" : { Range },
      "valueCodeableConcept" : { CodeableConcept },
      "intended" : <boolean>, // The plan for analysis
      "applied" : <boolean>, // This model characteristic is part of the analysis that was applied, whether or not the analysis followed the plan
      "variable" : [{ // A variable adjusted for in the adjusted analysis
        "variableDefinition" : { Reference(EvidenceVariable|Group) }, // R!  Description and definition of the variable
        "handling" : "<code>", // continuous | dichotomous | ordinal | polychotomous
        "valueCategory" : [{ CodeableConcept }], // Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable
        "valueQuantity" : [{ Quantity }], // Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable
        "valueRange" : [{ Range }] // Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variable
      }],
      "attribute" : [{ Content as for Evidence.statistic.attributeEstimate }] // An attribute of the model characteristic
    }]
  }],
  "certainty" : [{ // Certainty or quality of the evidence
    "description" : "<markdown>", // Textual description of certainty
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "type" : { CodeableConcept }, // Aspect of certainty being rated
    "rating" : [{ CodeableConcept }], // Assessment or judgement of the aspect
    "rater" : "<string>", // Individual or group who did the rating
    "subcomponent" : [{ Content as for Evidence.certainty }] // A domain or subdomain of certainty
  }]
}

Turtle Template

@prefix fhir: <http://hl7.org/fhir/> .doco


[ a fhir:Evidence;
  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:url [ uri ] ; # 0..1 Canonical identifier for this evidence, represented as a globally unique URI
  fhir:identifier  ( [ Identifier ] ... ) ; # 0..* Additional identifier for the summary
  fhir:version [ string ] ; # 0..1 Business version of this summary
  # versionAlgorithm[x] : 0..1 How to compare versions. One of these 2
    fhir:versionAlgorithm [  a fhir:string ; string ]
    fhir:versionAlgorithm [  a fhir:Coding ; Coding ]
  fhir:name [ string ] ; # 0..1 I Name for this summary (machine friendly)
  fhir:title [ string ] ; # 0..1 Name for this summary (human friendly)
  # citeAs[x] : 0..1 Citation for this evidence. One of these 2
    fhir:citeAs [  a fhir:Reference ; Reference(Citation) ]
    fhir:citeAs [  a fhir:markdown ; markdown ]
  fhir:status [ code ] ; # 1..1 draft | active | retired | unknown
  fhir:experimental [ boolean ] ; # 0..1 For testing purposes, not real usage
  fhir:date [ dateTime ] ; # 0..1 Date last changed
  fhir:approvalDate [ date ] ; # 0..1 When the summary was approved by publisher
  fhir:lastReviewDate [ date ] ; # 0..1 When the summary was last reviewed by the publisher
  fhir:author  ( [ ContactDetail ] ... ) ; # 0..* Who authored the content
  fhir:publisher [ string ] ; # 0..1 Name of the publisher/steward (organization or individual)
  fhir:contact  ( [ ContactDetail ] ... ) ; # 0..* Contact details for the publisher
  fhir:recorder  ( [ ContactDetail ] ... ) ; # 0..* Who entered the data for the evidence
  fhir:editor  ( [ ContactDetail ] ... ) ; # 0..* Who edited the content
  fhir:reviewer  ( [ ContactDetail ] ... ) ; # 0..* Who reviewed the content
  fhir:endorser  ( [ ContactDetail ] ... ) ; # 0..* Who endorsed the content
  fhir:useContext  ( [ UsageContext ] ... ) ; # 0..* The context that the content is intended to support
  fhir:purpose [ markdown ] ; # 0..1 Why this Evidence is defined
  fhir:copyright [ markdown ] ; # 0..1 Intellectual property ownership, may include restrictions on use
  fhir:copyrightLabel [ string ] ; # 0..1 Copyright holder and year(s)
  fhir:relatedArtifact  ( [ RelatedArtifact ] ... ) ; # 0..* Link or citation to artifact associated with the summary
  fhir:description [ markdown ] ; # 0..1 Description of the particular summary
  fhir:assertion [ markdown ] ; # 0..1 Declarative description of the Evidence
  fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnotes and/or explanatory notes
  fhir:variableDefinition ( [ # 0..* Description, classification, and definition of a single variable
    fhir:description [ markdown ] ; # 0..1 A text description or summary of the variable
    fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnotes and/or explanatory notes
    fhir:variableRole [ code ] ; # 1..1 population | exposure | outcome | covariate
    fhir:roleSubtype [ CodeableConcept ] ; # 0..1 Sub-classification of the role of the variable
    fhir:comparatorCategory [ string ] ; # 0..1 The reference value used for comparison
    fhir:observed [ Reference(EvidenceVariable|Group) ] ; # 0..1 Definition of the actual variable related to the statistic(s)
    fhir:intended [ Reference(EvidenceVariable|Group) ] ; # 0..1 Definition of the intended variable related to the Evidence
    fhir:directnessMatch [ CodeableConcept ] ; # 0..1 low | moderate | high | exact
  ] ... ) ;
  fhir:synthesisType  ( [ CodeableConcept ] ... ) ; # 0..* The design of the synthesis (combination of studies) that produced this evidence
  fhir:studyDesign  ( [ CodeableConcept ] ... ) ; # 0..* The design of the study that produced this evidence
  fhir:statistic ( [ # 0..* Values and parameters for a single statistic
    fhir:description [ markdown ] ; # 0..1 A natural language summary of the statistic
    fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnotes and/or explanatory notes
    fhir:statisticType [ CodeableConcept ] ; # 0..1 Type of statistic, e.g., relative risk
    fhir:category [ CodeableConcept ] ; # 0..1 Associated category for categorical variable
    fhir:quantity [ Quantity ] ; # 0..1 Statistic value
    fhir:numberOfEvents [ unsignedInt ] ; # 0..1 The number of events associated with the statistic
    fhir:numberAffected [ unsignedInt ] ; # 0..1 The number of participants affected
    fhir:sampleSize [ # 0..1 Count of participants in the study sample
      fhir:description [ markdown ] ; # 0..1 Textual description of sample size for statistic
      fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnote or explanatory note about the sample size
      fhir:numberOfStudies [ unsignedInt ] ; # 0..1 Number of contributing studies
      fhir:numberOfParticipants [ unsignedInt ] ; # 0..1 Total number of participants
      fhir:knownDataCount [ unsignedInt ] ; # 0..1 Number of participants with known results for measured variables
    ] ;
    fhir:attributeEstimate ( [ # 0..* An attribute of the Statistic
      fhir:description [ markdown ] ; # 0..1 Textual description of the attribute estimate
      fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnote or explanatory note about the estimate
      fhir:type [ CodeableConcept ] ; # 0..1 The type of attribute estimate, e.g., confidence interval or p value
      fhir:quantity [ Quantity ] ; # 0..1 The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measure
      fhir:level [ decimal ] ; # 0..1 Level of confidence interval, e.g., 0.95 for 95% confidence interval
      fhir:range [ Range ] ; # 0..1 Lower and upper bound values of the attribute estimate
      fhir:attributeEstimate  ( [ See Evidence.statistic.attributeEstimate ] ... ) ; # 0..* A nested attribute estimate; which is the attribute estimate of an attribute estimate
    ] ... ) ;
    fhir:modelCharacteristic ( [ # 0..* An aspect of the statistical model
      fhir:code [ CodeableConcept ] ; # 1..1 Model specification
      # value[x] : 0..1 The specific value (when paired with code). One of these 3
        fhir:value [  a fhir:SimpleQuantity ; Quantity(SimpleQuantity) ]
        fhir:value [  a fhir:Range ; Range ]
        fhir:value [  a fhir:CodeableConcept ; CodeableConcept ]
      fhir:intended [ boolean ] ; # 0..1 The plan for analysis
      fhir:applied [ boolean ] ; # 0..1 This model characteristic is part of the analysis that was applied, whether or not the analysis followed the plan
      fhir:variable ( [ # 0..* A variable adjusted for in the adjusted analysis
        fhir:variableDefinition [ Reference(EvidenceVariable|Group) ] ; # 1..1 Description and definition of the variable
        fhir:handling [ code ] ; # 0..1 continuous | dichotomous | ordinal | polychotomous
        fhir:valueCategory  ( [ CodeableConcept ] ... ) ; # 0..* Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable
        fhir:valueQuantity  ( [ Quantity ] ... ) ; # 0..* Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable
        fhir:valueRange  ( [ Range ] ... ) ; # 0..* Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variable
      ] ... ) ;
      fhir:attribute  ( [ See Evidence.statistic.attributeEstimate ] ... ) ; # 0..* An attribute of the model characteristic
    ] ... ) ;
  ] ... ) ;
  fhir:certainty ( [ # 0..* Certainty or quality of the evidence
    fhir:description [ markdown ] ; # 0..1 Textual description of certainty
    fhir:note  ( [ Annotation ] ... ) ; # 0..* Footnotes and/or explanatory notes
    fhir:type [ CodeableConcept ] ; # 0..1 Aspect of certainty being rated
    fhir:rating  ( [ CodeableConcept ] ... ) ; # 0..* Assessment or judgement of the aspect
    fhir:rater [ string ] ; # 0..1 Individual or group who did the rating
    fhir:subcomponent  ( [ See Evidence.certainty ] ... ) ; # 0..* A domain or subdomain of certainty
  ] ... ) ;
]

Changes from both R4 and R4B

Evidence
Evidence.versionAlgorithm[x]
  • Added Element
Evidence.citeAs[x]
  • Added Element
Evidence.experimental
  • Added Element
Evidence.recorder
  • Added Element
Evidence.purpose
  • Added Element
Evidence.copyrightLabel
  • Added Element
Evidence.assertion
  • Added Element
Evidence.variableDefinition
  • Added Element
Evidence.variableDefinition.description
  • Added Element
Evidence.variableDefinition.note
  • Added Element
Evidence.variableDefinition.variableRole
  • Added Mandatory Element
Evidence.variableDefinition.roleSubtype
  • Added Element
Evidence.variableDefinition.comparatorCategory
  • Added Element
Evidence.variableDefinition.observed
  • Added Element
Evidence.variableDefinition.intended
  • Added Element
Evidence.variableDefinition.directnessMatch
  • Added Element
Evidence.synthesisType
  • Added Element
Evidence.studyDesign
  • Added Element
Evidence.statistic
  • Added Element
Evidence.statistic.description
  • Added Element
Evidence.statistic.note
  • Added Element
Evidence.statistic.statisticType
  • Added Element
Evidence.statistic.category
  • Added Element
Evidence.statistic.quantity
  • Added Element
Evidence.statistic.numberOfEvents
  • Added Element
Evidence.statistic.numberAffected
  • Added Element
Evidence.statistic.sampleSize
  • Added Element
Evidence.statistic.sampleSize.description
  • Added Element
Evidence.statistic.sampleSize.note
  • Added Element
Evidence.statistic.sampleSize.numberOfStudies
  • Added Element
Evidence.statistic.sampleSize.numberOfParticipants
  • Added Element
Evidence.statistic.sampleSize.knownDataCount
  • Added Element
Evidence.statistic.attributeEstimate
  • Added Element
Evidence.statistic.attributeEstimate.description
  • Added Element
Evidence.statistic.attributeEstimate.note
  • Added Element
Evidence.statistic.attributeEstimate.type
  • Added Element
Evidence.statistic.attributeEstimate.quantity
  • Added Element
Evidence.statistic.attributeEstimate.level
  • Added Element
Evidence.statistic.attributeEstimate.range
  • Added Element
Evidence.statistic.attributeEstimate.attributeEstimate
  • Added Element
Evidence.statistic.modelCharacteristic
  • Added Element
Evidence.statistic.modelCharacteristic.code
  • Added Mandatory Element
Evidence.statistic.modelCharacteristic.value[x]
  • Added Element
Evidence.statistic.modelCharacteristic.intended
  • Added Element
Evidence.statistic.modelCharacteristic.applied
  • Added Element
Evidence.statistic.modelCharacteristic.variable
  • Added Element
Evidence.statistic.modelCharacteristic.variable.variableDefinition
  • Added Mandatory Element
Evidence.statistic.modelCharacteristic.variable.handling
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueCategory
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueQuantity
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueRange
  • Added Element
Evidence.statistic.modelCharacteristic.attribute
  • Added Element
Evidence.certainty
  • Added Element
Evidence.certainty.description
  • Added Element
Evidence.certainty.note
  • Added Element
Evidence.certainty.type
  • Added Element
Evidence.certainty.rating
  • Added Element
Evidence.certainty.rater
  • Added Element
Evidence.certainty.subcomponent
  • Added Element
Evidence.shortTitle
  • Deleted
Evidence.subtitle
  • Deleted
Evidence.jurisdiction
  • Deleted
Evidence.effectivePeriod
  • Deleted
Evidence.topic
  • Deleted
Evidence.exposureBackground
  • Deleted
Evidence.exposureVariant
  • Deleted
Evidence.outcome
  • Deleted

See the Full Difference for further information

This analysis is available for R4 as XML or JSON and for R4B as XML or JSON.

 

Additional definitions: Master Definition XML + JSON, XML Schema/Schematron + JSON Schema, ShEx (for Turtle) , the spreadsheet version & the dependency analysis

14.13.4.1 Terminology Bindings

Path ValueSet Type Documentation
Evidence.versionAlgorithm[x] VersionAlgorithm Extensible

Indicates the mechanism used to compare versions to determine which is more current.
Evidence.status PublicationStatus Required

The lifecycle status of an artifact.
Evidence.variableDefinition.variableRole EvidenceVariableRole (a valid code from VariableRole) Required

The role that the variable plays.
Evidence.variableDefinition.roleSubtype EvidenceVariableRoleSubtype (a valid code from EvidenceVariableRole icon) Extensible

The sub-role that the variable plays.
Evidence.variableDefinition.directnessMatch EvidenceDirectness icon Extensible

The quality of how direct the match is.
Evidence.synthesisType StatisticSynthesisType icon Extensible

Types of combining results from a body of evidence (eg. summary data meta-analysis).
Evidence.studyDesign StudyDesign Extensible

This is a set of terms for study design characteristics.
Evidence.statistic.statisticType StatisticType (a valid code from StatisticStatisticType icon) Extensible

The type of a statistic, e.g. relative risk or mean
Evidence.statistic.attributeEstimate.type AttributeEstimateType (a valid code from StatisticAttribute Estimate Type icon) Extensible

A statistic about a statistic, e.g. Confidence interval or p-value
Evidence.statistic.modelCharacteristic.code StatisticModelCode Extensible

The handling of the variable in statistical analysis for exposures or outcomes.
Evidence.statistic.modelCharacteristic.variable.handling EvidenceVariableHandling Required

The handling of the variable in statistical analysis for exposures or outcomes (E.g. Dichotomous, Continuous, Descriptive).
Evidence.certainty.type EvidenceCertaintyType Extensible

The aspect of quality, confidence, or certainty.
Evidence.certainty.rating EvidenceCertaintyRating Extensible

The assessment of quality, confidence, or certainty.

14.13.4.2 Constraints

UniqueKeyLevelLocationDescriptionExpression
img cnl-0Warning (base)Name should be usable as an identifier for the module by machine processing applications such as code generationname.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')
img cnl-1Warning Evidence.urlURL should not contain | or # - these characters make processing canonical references problematicexists() implies matches('^[^|# ]+$')



14.13.5 Search Parameters

Search parameters for this resource. See also the full list of search parameters for this resource, and check the Extensions registry for search parameters on extensions related to this resource. The common parameters also apply. See Searching for more information about searching in REST, messaging, and services.

Name Type Description Expression In Common
context token A use context assigned to the evidence (Evidence.useContext.value.ofType(CodeableConcept)) 30 Resources
context-quantity quantity A quantity- or range-valued use context assigned to the evidence (Evidence.useContext.value.ofType(Quantity)) | (Evidence.useContext.value.ofType(Range)) 30 Resources
context-type token A type of use context assigned to the evidence Evidence.useContext.code 30 Resources
context-type-quantity composite A use context type and quantity- or range-based value assigned to the evidence On Evidence.useContext:
  context-type: code
  context-quantity: value.ofType(Quantity) | value.ofType(Range)		 30 Resources
context-type-value composite A use context type and value assigned to the evidence On Evidence.useContext:
  context-type: code
  context: value.ofType(CodeableConcept)		 30 Resources
date date The evidence publication date Evidence.date 30 Resources
description string The description of the evidence Evidence.description 28 Resources
identifier token External identifier for the evidence Evidence.identifier 36 Resources
publisher string Name of the publisher of the evidence Evidence.publisher 31 Resources
status token The current status of the evidence Evidence.status 36 Resources
title string The human-friendly name of the evidence Evidence.title 27 Resources
url uri The uri that identifies the evidence Evidence.url 35 Resources
version token The business version of the evidence Evidence.version 31 Resources