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| Responsible Owner: Biomedical Research and Regulation Work Group | Standards Status: Informative |
Raw XML (canonical form + also see XML Format Specification)
Definition for Code SystemSubstanceRelationshipTypeExample
<?xml version="1.0" encoding="UTF-8"?> <CodeSystem xmlns="http://hl7.org/fhir"> <id value="substance-relationship-type"/> <meta> <lastUpdated value="2026-06-24T23:10:57.715+11:00"/> </meta> <text> <status value="generated"/> <div xmlns="http://www.w3.org/1999/xhtml"> <p class="res-header-id"> <b> Generated Narrative: CodeSystem substance-relationship-type</b> </p> <a name="substance-relationship-type"> </a> <a name="hcsubstance-relationship-type"> </a> <div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"> <p style="margin-bottom: 0px">Last updated: 2021-01-05T10:01:24.148+11:00</p> </div> <p> This case-sensitive code system <code> http://hl7.org/fhir/substance-relationship-type</code> defines the following codes: </p> <table class="codes"> <tr> <td style="white-space:nowrap"> <b> Code</b> </td> <td> <b> Display</b> </td> <td> <b> Definition</b> </td> </tr> <tr> <td style="white-space:nowrap">Salt <a name="substance-relationship-type-Salt"> </a> </td> <td> Salt to parent</td> <td/> </tr> <tr> <td style="white-space:nowrap">ActiveMoiety <a name="substance-relationship-type-ActiveMoiety"> </a> </td> <td> Active moiety</td> <td/> </tr> <tr> <td style="white-space:nowrap">StartingMaterial <a name="substance-relationship-type-StartingMaterial"> </a> </td> <td> Starting material for</td> <td/> </tr> <tr> <td style="white-space:nowrap">Polymorph <a name="substance-relationship-type-Polymorph"> </a> </td> <td> Polymorph of</td> <td/> </tr> <tr> <td style="white-space:nowrap">Impurity <a name="substance-relationship-type-Impurity"> </a> </td> <td> Impurity of</td> <td/> </tr> <tr> <td style="white-space:nowrap">TherapeuticTarget <a name="substance-relationship-type-TherapeuticTarget"> </a> </td> <td> Therapeutic target</td> <td> The substance acts therapeutically on the target.</td> </tr> <tr> <td style="white-space:nowrap">MetabolicTarget <a name="substance-relationship-type-MetabolicTarget"> </a> </td> <td> Metabolic target</td> <td> The substance is metabolised by or interacts with the target as part of metabolism.</td> </tr> <tr> <td style="white-space:nowrap">ToxicityTarget <a name="substance-relationship-type-ToxicityTarget"> </a> </td> <td> Toxicity target</td> <td> The substance interacts with the target in a way that contributes to toxicity.</td> </tr> <tr> <td style="white-space:nowrap">TargetUnknownEffect <a name="substance-relationship-type-TargetUnknownEffect"> </a> </td> <td> Target (unknown effect)</td> <td> The substance is known to interact with the target, but the effect is not characterised.</td> </tr> <tr> <td style="white-space:nowrap">GeneOfOrigin <a name="substance-relationship-type-GeneOfOrigin"> </a> </td> <td> Gene of origin</td> <td> The substance was derived from this gene (used e.g. for recombinant proteins and nucleic acid products).</td> </tr> </table> </div> </text> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg"> <valueCode value="brr"/> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="informative"/> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm"> <valueInteger value="1"/> </extension> <url value="http://hl7.org/fhir/substance-relationship-type"/> <identifier> <system value="urn:ietf:rfc:3986"/> <value value="urn:oid:2.16.840.1.113883.4.642.4.2088"/> </identifier> <version value="6.0.0-ballot4"/> <name value="SubstanceRelationshipTypeExample"/> <title value="Substance Relationship Type"/> <status value="active"/> <experimental value="true"/> <date value="2021-01-05T10:01:24+11:00"/> <publisher value="HL7 (FHIR Project)"/> <contact> <telecom> <system value="url"/> <value value="http://hl7.org/fhir"/> </telecom> <telecom> <system value="email"/> <value value="fhir@lists.hl7.org"/> </telecom> </contact> <description value="The relationship between two substance types."/> <jurisdiction> <coding> <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/> <code value="001"/> <display value="World"/> </coding> </jurisdiction> <caseSensitive value="true"/> <valueSet value="http://hl7.org/fhir/ValueSet/substance-relationship-type"/> <content value="complete"/> <concept> <code value="Salt"/> <display value="Salt to parent"/> </concept> <concept> <code value="ActiveMoiety"/> <display value="Active moiety"/> </concept> <concept> <code value="StartingMaterial"/> <display value="Starting material for"/> </concept> <concept> <code value="Polymorph"/> <display value="Polymorph of"/> </concept> <concept> <code value="Impurity"/> <display value="Impurity of"/> </concept> <concept> <code value="TherapeuticTarget"/> <display value="Therapeutic target"/> <definition value="The substance acts therapeutically on the target."/> </concept> <concept> <code value="MetabolicTarget"/> <display value="Metabolic target"/> <definition value="The substance is metabolised by or interacts with the target as part of metabolism."/> </concept> <concept> <code value="ToxicityTarget"/> <display value="Toxicity target"/> <definition value="The substance interacts with the target in a way that contributes to toxicity."/> </concept> <concept> <code value="TargetUnknownEffect"/> <display value="Target (unknown effect)"/> <definition value="The substance is known to interact with the target, but the effect is not characterised."/> </concept> <concept> <code value="GeneOfOrigin"/> <display value="Gene of origin"/> <definition value="The substance was derived from this gene (used e.g. for recombinant proteins and nucleic acid products)."/> </concept> </CodeSystem>
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.
FHIR ®© HL7.org 2011+. FHIR R6 hl7.fhir.r6.core#6.0.0-ballot4 generated on Wed, Jun 24, 2026 12:12+0000.
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