Certainty Rating of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19

@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

[a fhir:ArtifactAssessment ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "example-certainty-rating"] ; # 
  fhir:identifier ( [
     fhir:type [
       fhir:text [ fhir:v "FEvIR Object Identifier" ]
     ] ;
     fhir:system [ fhir:v "https://fevir.net"^^xsd:anyURI ] ;
     fhir:value [ fhir:v "27756" ] ;
     fhir:assigner [
       fhir:display [ fhir:v "Computable Publishing LLC" ]
     ]
  ] ) ; # 
  fhir:artifact [
     a fhir:Reference ;
     fhir:reference [ fhir:v "Evidence/example-stroke-alteplase-fatalICH" ] ;
     fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
     fhir:display [ fhir:v "Critically appraised summary of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19" ]
  ] ; # 
  fhir:date [ fhir:v "2021-11-02T14:48:59.890Z"^^xsd:dateTime] ; # 
  fhir:copyright [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/"] ; # 
  fhir:content ( [
     fhir:summary [ fhir:v "serious concerns with risk of bias, inconsistency, and imprecision" ] ;
     fhir:type [
       fhir:coding ( [
         fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "Overall" ] ;
         fhir:display [ fhir:v "Overall certainty" ]
       ] )
     ] ;
     fhir:classifier ( [
       fhir:coding ( [
         fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "very-low" ] ;
         fhir:display [ fhir:v "Very low quality" ]
       ] )
     ] ) ;
     fhir:author ( [
       fhir:display [ fhir:v "Brian S. Alper" ]
     ] ) ;
     fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ;
     fhir:component ( [
       fhir:summary [ fhir:v "risk of bias in both included trials" ] ;
       fhir:type [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "RiskOfBias" ] ;
           fhir:display [ fhir:v "Risk of bias" ]
         ] )
       ] ;
       fhir:classifier ( [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "serious-concern" ] ;
           fhir:display [ fhir:v "serious concern" ]
         ] )
       ] ) ;
       fhir:author ( [
         fhir:display [ fhir:v "Brian S. Alper" ]
       ] )
     ] [
       fhir:summary [ fhir:v "high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial effect estimates barely overlapping" ] ;
       fhir:type [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "Inconsistency" ] ;
           fhir:display [ fhir:v "Inconsistency" ]
         ] )
       ] ;
       fhir:classifier ( [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "serious-concern" ] ;
           fhir:display [ fhir:v "serious concern" ]
         ] )
       ] ) ;
       fhir:author ( [
         fhir:display [ fhir:v "Brian S. Alper" ]
       ] )
     ] [
       fhir:type [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "Indirectness" ] ;
           fhir:display [ fhir:v "Indirectness" ]
         ] )
       ] ;
       fhir:classifier ( [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "no-concern" ] ;
           fhir:display [ fhir:v "no serious concern" ]
         ] )
       ] ) ;
       fhir:author ( [
         fhir:display [ fhir:v "Brian S. Alper" ]
       ] )
     ] [
       fhir:summary [ fhir:v "95% confidence interval includes both large effects and no effects" ] ;
       fhir:type [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "Imprecision" ] ;
           fhir:display [ fhir:v "Imprecision" ]
         ] )
       ] ;
       fhir:classifier ( [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "serious-concern" ] ;
           fhir:display [ fhir:v "serious concern" ]
         ] )
       ] ) ;
       fhir:author ( [
         fhir:display [ fhir:v "Brian S. Alper" ]
       ] )
     ] [
       fhir:type [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "PublicationBias" ] ;
           fhir:display [ fhir:v "Publication bias" ]
         ] )
       ] ;
       fhir:classifier ( [
         fhir:coding ( [
           fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "no-concern" ] ;
           fhir:display [ fhir:v "no serious concern" ]
         ] )
       ] ) ;
       fhir:author ( [
         fhir:display [ fhir:v "Brian S. Alper" ]
       ] )
     ] )
  ] )] . # 

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