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Example MedicationRequest/medrx0317 (JSON)

Responsible Owner: Pharmacy Work GroupStandards Status: InformativeCompartments: Encounter, Group, Patient, Practitioner

Raw JSON (canonical form + also see JSON Format Specification)

Request for Intravenous Chemotherapy (inpatient order) - Alemtuzumab - completed with multiple dosageInstruction lines

{
  "resourceType" : "MedicationRequest",
  "id" : "medrx0317",
  "contained" : [{
    "resourceType" : "Medication",
    "id" : "med0303",
    "code" : {
      "coding" : [{
        "system" : "http://www.nlm.nih.gov/research/umls/rxnorm",
        "code" : "1594660",
        "display" : "alemtuzumab 10 MG/ML [Lemtrada]"
      }]
    }
  }],
  "identifier" : [{
    "use" : "official",
    "system" : "http://www.bmc.nl/portal/prescriptions",
    "value" : "12345689"
  }],
  "status" : "completed",
  "intent" : "order",
  "medication" : {
    "reference" : {
      "reference" : "#med0303"
    }
  },
  "subject" : {
    "reference" : "Patient/pat1",
    "display" : "Donald Duck"
  },
  "authoredOn" : "2015-01-15",
  "requester" : {
    "reference" : "Practitioner/f007",
    "display" : "Patrick Pump"
  },
  "reason" : [{
    "concept" : {
      "coding" : [{
        "system" : "http://snomed.info/sct",
        "code" : "92814006",
        "display" : "Chronic lymphoid leukemia, disease (disorder)"
      }]
    }
  }],
  "dosageInstruction" : {
    "step" : [{
      "component" : [{
        "text" : "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk",
        "additionalInstruction" : [{
          "text" : "Rapidly increase dose until tolerated"
        },
        {
          "text" : "Administer on alternate days"
        }],
        "timing" : {
          "repeat" : {
            "duration" : 12,
            "durationUnit" : "wk",
            "frequency" : 3,
            "period" : 1,
            "periodUnit" : "wk"
          }
        },
        "route" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "47625008",
            "display" : "Intravenous route"
          }]
        },
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "422145002",
            "display" : "Inject - dosing instruction imperative (qualifier value)"
          }]
        },
        "doseAndRate" : [{
          "type" : {
            "coding" : [{
              "system" : "http://terminology.hl7.org/CodeSystem/dose-rate-type",
              "code" : "ordered",
              "display" : "Ordered"
            }]
          },
          "doseQuantity" : {
            "value" : 3,
            "unit" : "mg",
            "system" : "http://unitsofmeasure.org",
            "code" : "mg"
          }
        }]
      }]
    },
    {
      "component" : [{
        "text" : "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk",
        "additionalInstruction" : [{
          "text" : "Rapidly increase dose until tolerated"
        },
        {
          "text" : "Administer on alternate days"
        }],
        "timing" : {
          "repeat" : {
            "duration" : 12,
            "durationUnit" : "wk",
            "frequency" : 3,
            "period" : 1,
            "periodUnit" : "wk"
          }
        },
        "route" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "47625008",
            "display" : "Intravenous route"
          }]
        },
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "422145002",
            "display" : "Inject - dosing instruction imperative (qualifier value)"
          }]
        },
        "doseAndRate" : [{
          "type" : {
            "coding" : [{
              "system" : "http://terminology.hl7.org/CodeSystem/dose-rate-type",
              "code" : "ordered",
              "display" : "Ordered"
            }]
          },
          "doseQuantity" : {
            "value" : 10,
            "unit" : "mg",
            "system" : "http://unitsofmeasure.org",
            "code" : "mg"
          }
        }]
      }]
    },
    {
      "component" : [{
        "text" : "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk",
        "additionalInstruction" : [{
          "text" : "Rapidly increase dose until tolerated"
        },
        {
          "text" : "Administer on alternate days"
        }],
        "timing" : {
          "repeat" : {
            "duration" : 12,
            "durationUnit" : "wk",
            "frequency" : 3,
            "period" : 1,
            "periodUnit" : "wk"
          }
        },
        "route" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "47625008",
            "display" : "Intravenous route"
          }]
        },
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "422145002",
            "display" : "Inject - dosing instruction imperative (qualifier value)"
          }]
        },
        "doseAndRate" : [{
          "type" : {
            "coding" : [{
              "system" : "http://terminology.hl7.org/CodeSystem/dose-rate-type",
              "code" : "ordered",
              "display" : "Ordered"
            }]
          },
          "doseQuantity" : {
            "value" : 30,
            "unit" : "mg",
            "system" : "http://unitsofmeasure.org",
            "code" : "mg"
          }
        }]
      }]
    }]
  }
}

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.