2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide
2022.1.1 - Release 2022.1
2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide
2022.1.1 - Release 2022.1
2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide, published by CDC / Security Risk Solutions, Inc. (SRS). This guide is not an authorized publication; it is the continuous build for version 2022.1.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/security-rs/opioid-cds-r4/ and changes regularly. See the Directory of published versions
| Active as of 2026-06-02 |
<ValueSet xmlns="http://hl7.org/fhir">
<id value="xylazine-urine-drug-screening-tests"/>
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<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: ValueSet xylazine-urine-drug-screening-tests</b></p><a name="xylazine-urine-drug-screening-tests"> </a><a name="hcxylazine-urine-drug-screening-tests"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="http://hl7.org/fhir/uv/cpg/STU1/StructureDefinition-cpg-computablevalueset.html">CPGComputableValueSet</a>, <a href="http://hl7.org/fhir/uv/cpg/STU1/StructureDefinition-cpg-executablevalueset.html">CPGExecutableValueSet</a></p></div><p style="border: black 1px dotted; background-color: #EEEEEE; padding: 8px; margin-bottom: 8px">Expansion based on Loinc v2.82</p><p>This value set contains 7 concepts</p><table class="codes"><tr><td><b>System</b></td><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td></tr><tr><td><a name="xylazine-urine-drug-screening-tests-http://loinc.org-103638-3"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap"> <a href="https://loinc.org/103638-3/">103638-3</a></td><td>4-hydroxy Xylazine [Mass/volume] in Urine by Confirmatory method</td></tr><tr><td><a name="xylazine-urine-drug-screening-tests-http://loinc.org-103639-1"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap"> <a href="https://loinc.org/103639-1/">103639-1</a></td><td>4-hydroxy Xylazine [Presence] in Urine by Confirmatory method</td></tr><tr><td><a name="xylazine-urine-drug-screening-tests-http://loinc.org-103640-9"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap"> <a href="https://loinc.org/103640-9/">103640-9</a></td><td>4-hydroxy Xylazine/Creatinine [Mass Ratio] in Urine by Confirmatory method</td></tr><tr><td><a name="xylazine-urine-drug-screening-tests-http://loinc.org-101808-4"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap"> <a href="https://loinc.org/101808-4/">101808-4</a></td><td>Xylazine [Mass/volume] in Urine by Confirmatory method</td></tr><tr><td><a name="xylazine-urine-drug-screening-tests-http://loinc.org-101809-2"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap"> <a href="https://loinc.org/101809-2/">101809-2</a></td><td>Xylazine [Presence] in Urine by Confirmatory method</td></tr><tr><td><a name="xylazine-urine-drug-screening-tests-http://loinc.org-101810-0"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap"> <a href="https://loinc.org/101810-0/">101810-0</a></td><td>Xylazine/Creatinine [Mass Ratio] in Urine by Confirmatory method</td></tr><tr><td><a name="xylazine-urine-drug-screening-tests-http://loinc.org-107608-2"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap"> <a href="https://loinc.org/107608-2/">107608-2</a></td><td>Xylazine [Presence] in Urine</td></tr></table></div>
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<valueCode value="computable"/>
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<extension
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<valueCode value="executable"/>
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<extension
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<valueString
value="This value set contains a point-in-time expansion enumerating the codes that meet the value set intent. As new versions of the code systems used by the value set are released, the contents of this expansion will need to be updated to incorporate newly defined codes that meet the value set intent. Before, and periodically during production use, the value set expansion contents SHOULD be updated. The value set expansion specifies the timestamp when the expansion was produced, SHOULD contain the parameters used for the expansion, and SHALL contain the codes that are obtained by evaluating the value set definition. If this is ONLY an executable value set, a distributable definition of the value set must be obtained to compute the updated expansion."/>
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<valueCode value="documentation"/>
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<valueMarkdown
value="Maintenance search expression: `multiaxial_descendantsof:(LP437281-1 OR LP435271-4) AND system:urine`. The compose anchors at two trunk LP codes - LP437281-1 and LP435271-4 - using `concept is-a` filters scoped to SYSTEM=LP7681-2 (urine) and CLASSTYPE=1 (lab test). To regenerate: re-run the search expression as a LOINC hierarchy query, add any newly-discovered trunk LP code as another is-a filter, then re-expand."/>
</extension>
</extension>
<url
value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/xylazine-urine-drug-screening-tests"/>
<identifier>
<system value="urn:ietf:rfc:3986"/>
<value value="urn:oid:2.16.840.1.113883.4.642.40.65.48.69"/>
</identifier>
<version value="2022.1.1"/>
<name value="XYLAZINE_URINE_DRUG_SCREENING_TESTS"/>
<title value="Xylazine drug urine screening tests"/>
<status value="active"/>
<experimental value="false"/>
<date value="2026-06-02T10:00:16-06:00"/>
<publisher value="CDC / Security Risk Solutions, Inc. (SRS)"/>
<contact>
<telecom>
<system value="url"/>
<value value="https://www.securityrisksolutions.com"/>
</telecom>
</contact>
<description
value="Individual tests and panels of tests of urine for xylazine"/>
<purpose
value="Identification of xylazine urine drug tests where results can be used when considering opioid therapy"/>
<copyright value="© CDC 2016+."/>
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<system value="http://loinc.org"/>
<filter>
<property value="concept"/>
<op value="is-a"/>
<value value="LP437281-1"/>
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<property value="SYSTEM"/>
<op value="="/>
<value value="LP7681-2"/>
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<filter>
<property value="CLASSTYPE"/>
<op value="="/>
<value value="1"/>
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<include>
<system value="http://loinc.org"/>
<filter>
<property value="concept"/>
<op value="is-a"/>
<value value="LP435271-4"/>
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<filter>
<property value="SYSTEM"/>
<op value="="/>
<value value="LP7681-2"/>
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<filter>
<property value="CLASSTYPE"/>
<op value="="/>
<value value="1"/>
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<identifier value="urn:uuid:bb2a5d13-9556-4713-bdef-8f33e28f5b8c"/>
<timestamp value="2026-06-02T16:00:16.531Z"/>
<total value="7"/>
<parameter>
<name value="used-codesystem"/>
<valueUri value="http://loinc.org|2.82"/>
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<parameter>
<name value="version"/>
<valueUri value="http://loinc.org|2.82"/>
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<contains>
<system value="http://loinc.org"/>
<code value="103638-3"/>
<display
value="4-hydroxy Xylazine [Mass/volume] in Urine by Confirmatory method"/>
</contains>
<contains>
<system value="http://loinc.org"/>
<code value="103639-1"/>
<display
value="4-hydroxy Xylazine [Presence] in Urine by Confirmatory method"/>
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<contains>
<system value="http://loinc.org"/>
<code value="103640-9"/>
<display
value="4-hydroxy Xylazine/Creatinine [Mass Ratio] in Urine by Confirmatory method"/>
</contains>
<contains>
<system value="http://loinc.org"/>
<code value="101808-4"/>
<display
value="Xylazine [Mass/volume] in Urine by Confirmatory method"/>
</contains>
<contains>
<system value="http://loinc.org"/>
<code value="101809-2"/>
<display value="Xylazine [Presence] in Urine by Confirmatory method"/>
</contains>
<contains>
<system value="http://loinc.org"/>
<code value="101810-0"/>
<display
value="Xylazine/Creatinine [Mass Ratio] in Urine by Confirmatory method"/>
</contains>
<contains>
<system value="http://loinc.org"/>
<code value="107608-2"/>
<display value="Xylazine [Presence] in Urine"/>
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