2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide
2022.1.1 - Release 2022.1
2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide
2022.1.1 - Release 2022.1
2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide, published by CDC / Security Risk Solutions, Inc. (SRS). This guide is not an authorized publication; it is the continuous build for version 2022.1.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/security-rs/opioid-cds-r4/ and changes regularly. See the Directory of published versions
| Active as of 2026-06-02 |
@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
# - resource -------------------------------------------------------------------
<http://hl7.org/fhir/ValueSet/xylazine-urine-drug-screening-tests> a fhir:ValueSet ;
fhir:nodeRole fhir:treeRoot ;
fhir:Resource.id [ fhir:value "xylazine-urine-drug-screening-tests"] ;
fhir:Resource.meta [
fhir:Meta.profile [
fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-computablevalueset" ;
fhir:index 0 ;
fhir:link <http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-computablevalueset>
], [
fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-executablevalueset" ;
fhir:index 1 ;
fhir:link <http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-executablevalueset>
]
] ;
fhir:DomainResource.text [
fhir:Narrative.status [ fhir:value "generated" ] ;
fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ValueSet xylazine-urine-drug-screening-tests</b></p><a name=\"xylazine-urine-drug-screening-tests\"> </a><a name=\"hcxylazine-urine-drug-screening-tests\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"http://hl7.org/fhir/uv/cpg/STU1/StructureDefinition-cpg-computablevalueset.html\">CPGComputableValueSet</a>, <a href=\"http://hl7.org/fhir/uv/cpg/STU1/StructureDefinition-cpg-executablevalueset.html\">CPGExecutableValueSet</a></p></div><p style=\"border: black 1px dotted; background-color: #EEEEEE; padding: 8px; margin-bottom: 8px\">Expansion based on Loinc v2.82</p><p>This value set contains 7 concepts</p><table class=\"codes\"><tr><td><b>System</b></td><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td><a name=\"xylazine-urine-drug-screening-tests-http://loinc.org-103638-3\"> </a><code>http://loinc.org</code></td><td style=\"white-space:nowrap\"> <a href=\"https://loinc.org/103638-3/\">103638-3</a></td><td>4-hydroxy Xylazine [Mass/volume] in Urine by Confirmatory method</td></tr><tr><td><a name=\"xylazine-urine-drug-screening-tests-http://loinc.org-103639-1\"> </a><code>http://loinc.org</code></td><td style=\"white-space:nowrap\"> <a href=\"https://loinc.org/103639-1/\">103639-1</a></td><td>4-hydroxy Xylazine [Presence] in Urine by Confirmatory method</td></tr><tr><td><a name=\"xylazine-urine-drug-screening-tests-http://loinc.org-103640-9\"> </a><code>http://loinc.org</code></td><td style=\"white-space:nowrap\"> <a href=\"https://loinc.org/103640-9/\">103640-9</a></td><td>4-hydroxy Xylazine/Creatinine [Mass Ratio] in Urine by Confirmatory method</td></tr><tr><td><a name=\"xylazine-urine-drug-screening-tests-http://loinc.org-101808-4\"> </a><code>http://loinc.org</code></td><td style=\"white-space:nowrap\"> <a href=\"https://loinc.org/101808-4/\">101808-4</a></td><td>Xylazine [Mass/volume] in Urine by Confirmatory method</td></tr><tr><td><a name=\"xylazine-urine-drug-screening-tests-http://loinc.org-101809-2\"> </a><code>http://loinc.org</code></td><td style=\"white-space:nowrap\"> <a href=\"https://loinc.org/101809-2/\">101809-2</a></td><td>Xylazine [Presence] in Urine by Confirmatory method</td></tr><tr><td><a name=\"xylazine-urine-drug-screening-tests-http://loinc.org-101810-0\"> </a><code>http://loinc.org</code></td><td style=\"white-space:nowrap\"> <a href=\"https://loinc.org/101810-0/\">101810-0</a></td><td>Xylazine/Creatinine [Mass Ratio] in Urine by Confirmatory method</td></tr><tr><td><a name=\"xylazine-urine-drug-screening-tests-http://loinc.org-107608-2\"> </a><code>http://loinc.org</code></td><td style=\"white-space:nowrap\"> <a href=\"https://loinc.org/107608-2/\">107608-2</a></td><td>Xylazine [Presence] in Urine</td></tr></table></div>"
] ;
fhir:DomainResource.extension [
fhir:index 0 ;
fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability" ] ;
fhir:Extension.valueCode [ fhir:value "computable" ]
], [
fhir:index 1 ;
fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability" ] ;
fhir:Extension.valueCode [ fhir:value "executable" ]
], [
fhir:index 2 ;
fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-usageWarning" ] ;
fhir:Extension.valueString [ fhir:value "This value set contains a point-in-time expansion enumerating the codes that meet the value set intent. As new versions of the code systems used by the value set are released, the contents of this expansion will need to be updated to incorporate newly defined codes that meet the value set intent. Before, and periodically during production use, the value set expansion contents SHOULD be updated. The value set expansion specifies the timestamp when the expansion was produced, SHOULD contain the parameters used for the expansion, and SHALL contain the codes that are obtained by evaluating the value set definition. If this is ONLY an executable value set, a distributable definition of the value set must be obtained to compute the updated expansion." ]
], [
fhir:index 3 ;
fhir:Element.extension [
fhir:index 0 ;
fhir:Extension.url [ fhir:value "type" ] ;
fhir:Extension.valueCode [ fhir:value "documentation" ]
], [
fhir:index 1 ;
fhir:Extension.url [ fhir:value "text" ] ;
fhir:Extension.valueMarkdown [ fhir:value "Maintenance search expression: `multiaxial_descendantsof:(LP437281-1 OR LP435271-4) AND system:urine`. The compose anchors at two trunk LP codes - LP437281-1 and LP435271-4 - using `concept is-a` filters scoped to SYSTEM=LP7681-2 (urine) and CLASSTYPE=1 (lab test). To regenerate: re-run the search expression as a LOINC hierarchy query, add any newly-discovered trunk LP code as another is-a filter, then re-expand." ]
] ;
fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/cqf-artifactComment" ]
] ;
fhir:ValueSet.url [ fhir:value "http://fhir.org/guides/cdc/opioid-cds/ValueSet/xylazine-urine-drug-screening-tests"] ;
fhir:ValueSet.identifier [
fhir:index 0 ;
fhir:Identifier.system [ fhir:value "urn:ietf:rfc:3986" ] ;
fhir:Identifier.value [ fhir:value "urn:oid:2.16.840.1.113883.4.642.40.65.48.69" ]
] ;
fhir:ValueSet.version [ fhir:value "2022.1.1"] ;
fhir:ValueSet.name [ fhir:value "XYLAZINE_URINE_DRUG_SCREENING_TESTS"] ;
fhir:ValueSet.title [ fhir:value "Xylazine drug urine screening tests"] ;
fhir:ValueSet.status [ fhir:value "active"] ;
fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean] ;
fhir:ValueSet.date [ fhir:value "2026-06-02T10:00:16-06:00"^^xsd:dateTime] ;
fhir:ValueSet.publisher [ fhir:value "CDC / Security Risk Solutions, Inc. (SRS)"] ;
fhir:ValueSet.contact [
fhir:index 0 ;
fhir:ContactDetail.telecom [
fhir:index 0 ;
fhir:ContactPoint.system [ fhir:value "url" ] ;
fhir:ContactPoint.value [ fhir:value "https://www.securityrisksolutions.com" ]
]
] ;
fhir:ValueSet.description [ fhir:value "Individual tests and panels of tests of urine for xylazine"] ;
fhir:ValueSet.purpose [ fhir:value "Identification of xylazine urine drug tests where results can be used when considering opioid therapy"] ;
fhir:ValueSet.copyright [ fhir:value "© CDC 2016+."] ;
fhir:ValueSet.compose [
fhir:ValueSet.compose.include [
fhir:index 0 ;
fhir:ValueSet.compose.include.system [ fhir:value "http://loinc.org" ] ;
fhir:ValueSet.compose.include.filter [
fhir:index 0 ;
fhir:ValueSet.compose.include.filter.property [ fhir:value "concept" ] ;
fhir:ValueSet.compose.include.filter.op [ fhir:value "is-a" ] ;
fhir:ValueSet.compose.include.filter.value [ fhir:value "LP437281-1" ]
], [
fhir:index 1 ;
fhir:ValueSet.compose.include.filter.property [ fhir:value "SYSTEM" ] ;
fhir:ValueSet.compose.include.filter.op [ fhir:value "=" ] ;
fhir:ValueSet.compose.include.filter.value [ fhir:value "LP7681-2" ]
], [
fhir:index 2 ;
fhir:ValueSet.compose.include.filter.property [ fhir:value "CLASSTYPE" ] ;
fhir:ValueSet.compose.include.filter.op [ fhir:value "=" ] ;
fhir:ValueSet.compose.include.filter.value [ fhir:value "1" ]
]
], [
fhir:index 1 ;
fhir:ValueSet.compose.include.system [ fhir:value "http://loinc.org" ] ;
fhir:ValueSet.compose.include.filter [
fhir:index 0 ;
fhir:ValueSet.compose.include.filter.property [ fhir:value "concept" ] ;
fhir:ValueSet.compose.include.filter.op [ fhir:value "is-a" ] ;
fhir:ValueSet.compose.include.filter.value [ fhir:value "LP435271-4" ]
], [
fhir:index 1 ;
fhir:ValueSet.compose.include.filter.property [ fhir:value "SYSTEM" ] ;
fhir:ValueSet.compose.include.filter.op [ fhir:value "=" ] ;
fhir:ValueSet.compose.include.filter.value [ fhir:value "LP7681-2" ]
], [
fhir:index 2 ;
fhir:ValueSet.compose.include.filter.property [ fhir:value "CLASSTYPE" ] ;
fhir:ValueSet.compose.include.filter.op [ fhir:value "=" ] ;
fhir:ValueSet.compose.include.filter.value [ fhir:value "1" ]
]
]
] ;
fhir:ValueSet.expansion [
fhir:ValueSet.expansion.identifier [ fhir:value "urn:uuid:bb2a5d13-9556-4713-bdef-8f33e28f5b8c" ] ;
fhir:ValueSet.expansion.timestamp [ fhir:value "2026-06-02T16:00:16.531Z"^^xsd:dateTime ] ;
fhir:ValueSet.expansion.total [ fhir:value "7"^^xsd:integer ] ;
fhir:ValueSet.expansion.parameter [
fhir:index 0 ;
fhir:ValueSet.expansion.parameter.name [ fhir:value "used-codesystem" ] ;
fhir:ValueSet.expansion.parameter.valueUri [ fhir:value "http://loinc.org|2.82" ]
], [
fhir:index 1 ;
fhir:ValueSet.expansion.parameter.name [ fhir:value "version" ] ;
fhir:ValueSet.expansion.parameter.valueUri [ fhir:value "http://loinc.org|2.82" ]
] ;
fhir:ValueSet.expansion.contains [
fhir:index 0 ;
fhir:ValueSet.expansion.contains.system [ fhir:value "http://loinc.org" ] ;
fhir:ValueSet.expansion.contains.code [ fhir:value "103638-3" ] ;
fhir:ValueSet.expansion.contains.display [ fhir:value "4-hydroxy Xylazine [Mass/volume] in Urine by Confirmatory method" ]
], [
fhir:index 1 ;
fhir:ValueSet.expansion.contains.system [ fhir:value "http://loinc.org" ] ;
fhir:ValueSet.expansion.contains.code [ fhir:value "103639-1" ] ;
fhir:ValueSet.expansion.contains.display [ fhir:value "4-hydroxy Xylazine [Presence] in Urine by Confirmatory method" ]
], [
fhir:index 2 ;
fhir:ValueSet.expansion.contains.system [ fhir:value "http://loinc.org" ] ;
fhir:ValueSet.expansion.contains.code [ fhir:value "103640-9" ] ;
fhir:ValueSet.expansion.contains.display [ fhir:value "4-hydroxy Xylazine/Creatinine [Mass Ratio] in Urine by Confirmatory method" ]
], [
fhir:index 3 ;
fhir:ValueSet.expansion.contains.system [ fhir:value "http://loinc.org" ] ;
fhir:ValueSet.expansion.contains.code [ fhir:value "101808-4" ] ;
fhir:ValueSet.expansion.contains.display [ fhir:value "Xylazine [Mass/volume] in Urine by Confirmatory method" ]
], [
fhir:index 4 ;
fhir:ValueSet.expansion.contains.system [ fhir:value "http://loinc.org" ] ;
fhir:ValueSet.expansion.contains.code [ fhir:value "101809-2" ] ;
fhir:ValueSet.expansion.contains.display [ fhir:value "Xylazine [Presence] in Urine by Confirmatory method" ]
], [
fhir:index 5 ;
fhir:ValueSet.expansion.contains.system [ fhir:value "http://loinc.org" ] ;
fhir:ValueSet.expansion.contains.code [ fhir:value "101810-0" ] ;
fhir:ValueSet.expansion.contains.display [ fhir:value "Xylazine/Creatinine [Mass Ratio] in Urine by Confirmatory method" ]
], [
fhir:index 6 ;
fhir:ValueSet.expansion.contains.system [ fhir:value "http://loinc.org" ] ;
fhir:ValueSet.expansion.contains.code [ fhir:value "107608-2" ] ;
fhir:ValueSet.expansion.contains.display [ fhir:value "Xylazine [Presence] in Urine" ]
]
] .
# - ontology header ------------------------------------------------------------
<http://hl7.org/fhir/ValueSet/xylazine-urine-drug-screening-tests.ttl> a owl:Ontology ;
owl:imports fhir:fhir.ttl ;
owl:versionIRI <http://build.fhir.org/ValueSet/xylazine-urine-drug-screening-tests.ttl> .
IG © 2019+ CDC / Security Risk Solutions, Inc. (SRS). Package fhir.cdc.opioid-cds-r4#2022.1.1 based on FHIR 4.0.1. Generated 2026-06-27
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