HIV Screening Clinical Guidelines Implementation Guide, published by National Association of Community Health Centers, Inc. (NACHC). This guide is not an authorized publication; it is the continuous build for version 0.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/cqframework/hiv-cds/ and changes regularly. See the Directory of published versions

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Resource Profile: Injection Drug Use

Injection Drug Use

Usage:

• Examples for this Resource Profile: MedicationStatement/injection-drug-use-example

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

• Differential Table
• Key Elements Table
• Snapshot Table
• Statistics/References
• All

This structure is derived from QICoreMedicationStatement

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	QICoreMedicationStatement	Record of medication being taken by a patient
medication[x]	S	1..1	CodeableConcept	Injection Drug Use Binding: Injection Drug Use Codes (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
MedicationStatement.medication[x]	required	InjectionDrugUseCodes http://fhir.org/guides/nachc/hiv-cds/ValueSet/nachc-f1-de201 from this IG

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	QICoreMedicationStatement	Record of medication being taken by a patient
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
status	?!SΣ	1..1	code	active | completed | entered-in-error | intended | stopped | on-hold | unknown | not-taken Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
medication[x]	SΣ	1..1	CodeableConcept	Injection Drug Use Binding: Injection Drug Use Codes (required)
subject	SΣ	1..1	Reference(QICorePatient)	Who is/was taking the medication
effective[x]	SΣ	0..1		The date/time or interval when the medication is/was/will be taken
effectiveDateTime			dateTime
effectivePeriod			Period
dateAsserted	SΣ	1..1	dateTime	When the statement was asserted?
informationSource	S	0..1	Reference(QICorePatient | QICorePractitioner | QICoreRelatedPerson)	Person or organization that provided the information about the taking of this medication
derivedFrom	S	0..*	Reference(Resource)	Additional supporting information
dosage		0..*	Dosage	Details of how medication is/was taken or should be taken
modifierExtension	?!Σ	0..*	Extension	Extension
timing	SΣ	0..1	Timing	When medication should be administered
route	SΣ	0..1	CodeableConcept	How drug should enter body Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
doseAndRate	SΣ	0..*	Element	Amount of medication administered
dose[x]	SΣ	0..1		Amount of medication per dose
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 from the FHIR Standard
MedicationStatement.medication[x]	required	InjectionDrugUseCodes http://fhir.org/guides/nachc/hiv-cds/ValueSet/nachc-f1-de201 from this IG
MedicationStatement.dosage.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	QICoreMedicationStatement	Record of medication being taken by a patient
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	External identifier
basedOn	Σ	0..*	Reference(MedicationRequest | CarePlan | ServiceRequest)	Fulfils plan, proposal or order
partOf	Σ	0..*	Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Observation)	Part of referenced event
status	?!SΣ	1..1	code	active | completed | entered-in-error | intended | stopped | on-hold | unknown | not-taken Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
statusReason		0..*	CodeableConcept	Reason for current status Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement.
category	Σ	0..1	CodeableConcept	Type of medication usage Binding: Medication usage category codes (preferred): A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.
medication[x]	SΣ	1..1	CodeableConcept	Injection Drug Use Binding: Injection Drug Use Codes (required)
subject	SΣ	1..1	Reference(QICorePatient)	Who is/was taking the medication
context	Σ	0..1	Reference(Encounter | EpisodeOfCare)	Encounter / Episode associated with MedicationStatement
effective[x]	SΣ	0..1		The date/time or interval when the medication is/was/will be taken
effectiveDateTime			dateTime
effectivePeriod			Period
dateAsserted	SΣ	1..1	dateTime	When the statement was asserted?
informationSource	S	0..1	Reference(QICorePatient | QICorePractitioner | QICoreRelatedPerson)	Person or organization that provided the information about the taking of this medication
derivedFrom	S	0..*	Reference(Resource)	Additional supporting information
reasonCode		0..*	CodeableConcept	Reason for why the medication is being/was taken Binding: Condition/Problem/DiagnosisCodes (example): A coded concept identifying why the medication is being taken.
reasonReference		0..*	Reference(Condition | Observation | DiagnosticReport)	Condition or observation that supports why the medication is being/was taken
note		0..*	Annotation	Further information about the statement
dosage		0..*	Dosage	Details of how medication is/was taken or should be taken
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extension
sequence	Σ	0..1	integer	The order of the dosage instructions
text	Σ	0..1	string	Free text dosage instructions e.g. SIG
additionalInstruction	Σ	0..*	CodeableConcept	Supplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness" Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".
patientInstruction	Σ	0..1	string	Patient or consumer oriented instructions
timing	SΣ	0..1	Timing	When medication should be administered
asNeeded[x]	Σ	0..1		Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
asNeededBoolean			boolean
asNeededCodeableConcept			CodeableConcept
site	Σ	0..1	CodeableConcept	Body site to administer to Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
route	SΣ	0..1	CodeableConcept	How drug should enter body Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
method	Σ	0..1	CodeableConcept	Technique for administering medication Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
doseAndRate	SΣ	0..*	Element	Amount of medication administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
type	Σ	0..1	CodeableConcept	The kind of dose or rate specified Binding: DoseAndRateType (example): The kind of dose or rate specified.
dose[x]	SΣ	0..1		Amount of medication per dose
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
rate[x]	Σ	0..1		Amount of medication per unit of time
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
maxDosePerPeriod	Σ	0..1	Ratio	Upper limit on medication per unit of time
maxDosePerAdministration	Σ	0..1	SimpleQuantity	Upper limit on medication per administration
maxDosePerLifetime	Σ	0..1	SimpleQuantity	Upper limit on medication per lifetime of the patient
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.language	preferred	CommonLanguages Additional Bindings Purpose AllLanguages Max Binding http://hl7.org/fhir/ValueSet/languages from the FHIR Standard
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 from the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes from the FHIR Standard
MedicationStatement.category	preferred	Medication usage category codes http://hl7.org/fhir/ValueSet/medication-statement-category from the FHIR Standard
MedicationStatement.medication[x]	required	InjectionDrugUseCodes http://fhir.org/guides/nachc/hiv-cds/ValueSet/nachc-f1-de201 from this IG
MedicationStatement.reasonCode	example	Condition/Problem/DiagnosisCodes http://hl7.org/fhir/ValueSet/condition-code from the FHIR Standard
MedicationStatement.dosage.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes from the FHIR Standard
MedicationStatement.dosage.asNeeded[x]	example	SNOMEDCTMedicationAsNeededReasonCodes http://hl7.org/fhir/ValueSet/medication-as-needed-reason from the FHIR Standard
MedicationStatement.dosage.site	example	SNOMEDCTAnatomicalStructureForAdministrationSiteCodes http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationStatement.dosage.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard
MedicationStatement.dosage.method	example	SNOMEDCTAdministrationMethodCodes http://hl7.org/fhir/ValueSet/administration-method-codes from the FHIR Standard
MedicationStatement.dosage.doseAndRate.type	example	DoseAndRateType http://hl7.org/fhir/ValueSet/dose-rate-type from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

This structure is derived from QICoreMedicationStatement

Summary

Mandatory: 1 element
Must-Support: 1 element

Differential View

This structure is derived from QICoreMedicationStatement

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	QICoreMedicationStatement	Record of medication being taken by a patient
medication[x]	S	1..1	CodeableConcept	Injection Drug Use Binding: Injection Drug Use Codes (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
MedicationStatement.medication[x]	required	InjectionDrugUseCodes http://fhir.org/guides/nachc/hiv-cds/ValueSet/nachc-f1-de201 from this IG

Key Elements View

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	QICoreMedicationStatement	Record of medication being taken by a patient
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
status	?!SΣ	1..1	code	active | completed | entered-in-error | intended | stopped | on-hold | unknown | not-taken Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
medication[x]	SΣ	1..1	CodeableConcept	Injection Drug Use Binding: Injection Drug Use Codes (required)
subject	SΣ	1..1	Reference(QICorePatient)	Who is/was taking the medication
effective[x]	SΣ	0..1		The date/time or interval when the medication is/was/will be taken
effectiveDateTime			dateTime
effectivePeriod			Period
dateAsserted	SΣ	1..1	dateTime	When the statement was asserted?
informationSource	S	0..1	Reference(QICorePatient | QICorePractitioner | QICoreRelatedPerson)	Person or organization that provided the information about the taking of this medication
derivedFrom	S	0..*	Reference(Resource)	Additional supporting information
dosage		0..*	Dosage	Details of how medication is/was taken or should be taken
modifierExtension	?!Σ	0..*	Extension	Extension
timing	SΣ	0..1	Timing	When medication should be administered
route	SΣ	0..1	CodeableConcept	How drug should enter body Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
doseAndRate	SΣ	0..*	Element	Amount of medication administered
dose[x]	SΣ	0..1		Amount of medication per dose
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 from the FHIR Standard
MedicationStatement.medication[x]	required	InjectionDrugUseCodes http://fhir.org/guides/nachc/hiv-cds/ValueSet/nachc-f1-de201 from this IG
MedicationStatement.dosage.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Snapshot View

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	QICoreMedicationStatement	Record of medication being taken by a patient
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	External identifier
basedOn	Σ	0..*	Reference(MedicationRequest | CarePlan | ServiceRequest)	Fulfils plan, proposal or order
partOf	Σ	0..*	Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Observation)	Part of referenced event
status	?!SΣ	1..1	code	active | completed | entered-in-error | intended | stopped | on-hold | unknown | not-taken Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
statusReason		0..*	CodeableConcept	Reason for current status Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement.
category	Σ	0..1	CodeableConcept	Type of medication usage Binding: Medication usage category codes (preferred): A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.
medication[x]	SΣ	1..1	CodeableConcept	Injection Drug Use Binding: Injection Drug Use Codes (required)
subject	SΣ	1..1	Reference(QICorePatient)	Who is/was taking the medication
context	Σ	0..1	Reference(Encounter | EpisodeOfCare)	Encounter / Episode associated with MedicationStatement
effective[x]	SΣ	0..1		The date/time or interval when the medication is/was/will be taken
effectiveDateTime			dateTime
effectivePeriod			Period
dateAsserted	SΣ	1..1	dateTime	When the statement was asserted?
informationSource	S	0..1	Reference(QICorePatient | QICorePractitioner | QICoreRelatedPerson)	Person or organization that provided the information about the taking of this medication
derivedFrom	S	0..*	Reference(Resource)	Additional supporting information
reasonCode		0..*	CodeableConcept	Reason for why the medication is being/was taken Binding: Condition/Problem/DiagnosisCodes (example): A coded concept identifying why the medication is being taken.
reasonReference		0..*	Reference(Condition | Observation | DiagnosticReport)	Condition or observation that supports why the medication is being/was taken
note		0..*	Annotation	Further information about the statement
dosage		0..*	Dosage	Details of how medication is/was taken or should be taken
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extension
sequence	Σ	0..1	integer	The order of the dosage instructions
text	Σ	0..1	string	Free text dosage instructions e.g. SIG
additionalInstruction	Σ	0..*	CodeableConcept	Supplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness" Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".
patientInstruction	Σ	0..1	string	Patient or consumer oriented instructions
timing	SΣ	0..1	Timing	When medication should be administered
asNeeded[x]	Σ	0..1		Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
asNeededBoolean			boolean
asNeededCodeableConcept			CodeableConcept
site	Σ	0..1	CodeableConcept	Body site to administer to Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
route	SΣ	0..1	CodeableConcept	How drug should enter body Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
method	Σ	0..1	CodeableConcept	Technique for administering medication Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
doseAndRate	SΣ	0..*	Element	Amount of medication administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
type	Σ	0..1	CodeableConcept	The kind of dose or rate specified Binding: DoseAndRateType (example): The kind of dose or rate specified.
dose[x]	SΣ	0..1		Amount of medication per dose
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
rate[x]	Σ	0..1		Amount of medication per unit of time
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
maxDosePerPeriod	Σ	0..1	Ratio	Upper limit on medication per unit of time
maxDosePerAdministration	Σ	0..1	SimpleQuantity	Upper limit on medication per administration
maxDosePerLifetime	Σ	0..1	SimpleQuantity	Upper limit on medication per lifetime of the patient
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.language	preferred	CommonLanguages Additional Bindings Purpose AllLanguages Max Binding http://hl7.org/fhir/ValueSet/languages from the FHIR Standard
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 from the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes from the FHIR Standard
MedicationStatement.category	preferred	Medication usage category codes http://hl7.org/fhir/ValueSet/medication-statement-category from the FHIR Standard
MedicationStatement.medication[x]	required	InjectionDrugUseCodes http://fhir.org/guides/nachc/hiv-cds/ValueSet/nachc-f1-de201 from this IG
MedicationStatement.reasonCode	example	Condition/Problem/DiagnosisCodes http://hl7.org/fhir/ValueSet/condition-code from the FHIR Standard
MedicationStatement.dosage.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes from the FHIR Standard
MedicationStatement.dosage.asNeeded[x]	example	SNOMEDCTMedicationAsNeededReasonCodes http://hl7.org/fhir/ValueSet/medication-as-needed-reason from the FHIR Standard
MedicationStatement.dosage.site	example	SNOMEDCTAnatomicalStructureForAdministrationSiteCodes http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationStatement.dosage.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard
MedicationStatement.dosage.method	example	SNOMEDCTAdministrationMethodCodes http://hl7.org/fhir/ValueSet/administration-method-codes from the FHIR Standard
MedicationStatement.dosage.doseAndRate.type	example	DoseAndRateType http://hl7.org/fhir/ValueSet/dose-rate-type from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

This structure is derived from QICoreMedicationStatement

Summary

Mandatory: 1 element
Must-Support: 1 element

Other representations of profile: CSV, Excel, Schematron