WHO Antenatal Care Guideline Implementation Guide, published by World Health Organization (WHO). This guide is not an authorized publication; it is the continuous build for version 0.3.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/WorldHealthOrganization/smart-anc/ and changes regularly. See the Directory of published versions

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Resource Profile: ANC AllergyIntolerance

ANC AllergyIntolerance

Usage:

• Refer to this Resource Profile: ANC CarePlan

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

• Differential Table
• Key Elements Table
• Snapshot Table
• Statistics/References
• All

This structure is derived from WHOAllergyIntolerance

Name	Flags	Card.	Type	Description & Constraints
AllergyIntolerance		0..*	WHOAllergyIntolerance	Allergy or Intolerance (generally: Risk of adverse reaction to a substance)
patient		1..1	Reference(ANC Patient)	Who the sensitivity is for
encounter		0..1	Reference(ANC Encounter)	Encounter when the allergy or intolerance was asserted
recorder		0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Who recorded the sensitivity
asserter		0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Source of the information about the allergy
Documentation for this format

Name	Flags	Card.	Type	Description & Constraints
AllergyIntolerance	C	0..*	WHOAllergyIntolerance	Allergy or Intolerance (generally: Risk of adverse reaction to a substance) ait-1: AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error. ait-2: AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error 1: extension: reasonRefuted is only permitted if status is refuted
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
resolutionAge		0..1	Age	Age that the allergy or intolerance resolved URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-resolutionAge
reasonRefuted	SC	0..1	CodeableConcept	Explanation associated with refuted status URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-reasonRefuted
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..*	Identifier	External ids for this item
use	?!SΣ	1..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
system	SΣ	1..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient
value	SΣ	1..1	string	The value that is unique Example General: 123456
clinicalStatus	?!SΣC	0..1	CodeableConcept	active | inactive | resolved Binding: AllergyIntoleranceClinicalStatusCodes (required): The clinical status of the allergy or intolerance.
verificationStatus	?!SΣC	1..1	CodeableConcept	unconfirmed | confirmed | refuted | entered-in-error Binding: AllergyIntoleranceVerificationStatusCodes (required): Assertion about certainty associated with a propensity, or potential risk, of a reaction to the identified substance.
type	SΣ	0..1	code	allergy | intolerance - Underlying mechanism (if known) Binding: AllergyIntoleranceType (required): Identification of the underlying physiological mechanism for a Reaction Risk.
category	SΣ	0..*	code	food | medication | environment | biologic Binding: AllergyIntoleranceCategory (required): Category of an identified substance associated with allergies or intolerances.
criticality	SΣ	0..1	code	low | high | unable-to-assess Binding: AllergyIntoleranceCriticality (required): Estimate of the potential clinical harm, or seriousness, of a reaction to an identified substance.
code	SΣ	1..1	CodeableConcept	Code that identifies the allergy or intolerance Binding: AllergyIntoleranceSubstance/Product,ConditionAndNegationCodes (example): Type of the substance/product, allergy or intolerance condition, or negation/exclusion codes for reporting no known allergies.
patient	SΣ	1..1	Reference(ANC Patient)	Who the sensitivity is for
encounter	S	0..1	Reference(ANC Encounter)	Encounter when the allergy or intolerance was asserted
recordedDate	S	0..1	dateTime	Date first version of the resource instance was recorded
recorder	S	0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Who recorded the sensitivity
asserter	SΣ	0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Source of the information about the allergy
reaction	S	0..*	BackboneElement	Adverse Reaction Events linked to exposure to substance
reaction-duration	S	0..1	Duration	How long Manifestations persisted URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-duration
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
manifestation	S	1..*	CodeableConcept	Clinical symptoms/signs associated with the Event Binding: SNOMEDCTClinicalFindings (example): Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction Event.
onset	S	0..1	dateTime	Date(/time) when manifestations showed
severity	S	0..1	code	mild | moderate | severe (of event as a whole) Binding: AllergyIntoleranceSeverity (required): Clinical assessment of the severity of a reaction event as a whole, potentially considering multiple different manifestations.
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
AllergyIntolerance.identifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|4.0.1 from the FHIR Standard
AllergyIntolerance.clinicalStatus	required	AllergyIntoleranceClinicalStatusCodes http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|4.0.1 from the FHIR Standard
AllergyIntolerance.verificationStatus	required	AllergyIntoleranceVerificationStatusCodes http://hl7.org/fhir/ValueSet/allergyintolerance-verification|4.0.1 from the FHIR Standard
AllergyIntolerance.type	required	AllergyIntoleranceType http://hl7.org/fhir/ValueSet/allergy-intolerance-type|4.0.1 from the FHIR Standard
AllergyIntolerance.category	required	AllergyIntoleranceCategory http://hl7.org/fhir/ValueSet/allergy-intolerance-category|4.0.1 from the FHIR Standard
AllergyIntolerance.criticality	required	AllergyIntoleranceCriticality http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|4.0.1 from the FHIR Standard
AllergyIntolerance.code	example	AllergyIntoleranceSubstance/Product,ConditionAndNegationCodes http://hl7.org/fhir/ValueSet/allergyintolerance-code from the FHIR Standard
AllergyIntolerance.reaction.manifestation	example	SNOMEDCTClinicalFindings http://hl7.org/fhir/ValueSet/clinical-findings from the FHIR Standard
AllergyIntolerance.reaction.severity	required	AllergyIntoleranceSeverity http://hl7.org/fhir/ValueSet/reaction-event-severity|4.0.1 from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
1	error	AllergyIntolerance	extension: reasonRefuted is only permitted if status is refuted : verificationStatus.coding.code = 'refuted' or extension.where(url='http://hl7.org/fhir/StructureDefinition/allergyintolerance-reasonRefuted').empty()
ait-1	error	AllergyIntolerance	AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error. : verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').exists() or clinicalStatus.exists()
ait-2	error	AllergyIntolerance	AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error : verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').empty() or clinicalStatus.empty()
dom-2	error	AllergyIntolerance	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	AllergyIntolerance	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	AllergyIntolerance	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	AllergyIntolerance	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	AllergyIntolerance	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Name	Flags	Card.	Type	Description & Constraints
AllergyIntolerance	C	0..*	WHOAllergyIntolerance	Allergy or Intolerance (generally: Risk of adverse reaction to a substance) ait-1: AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error. ait-2: AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error 1: extension: reasonRefuted is only permitted if status is refuted
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
resolutionAge		0..1	Age	Age that the allergy or intolerance resolved URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-resolutionAge
reasonRefuted	SC	0..1	CodeableConcept	Explanation associated with refuted status URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-reasonRefuted
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..*	Identifier	External ids for this item
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
use	?!SΣ	1..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
type	Σ	0..1	CodeableConcept	Description of identifier Binding: Identifier Type Codes (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.
system	SΣ	1..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient
value	SΣ	1..1	string	The value that is unique Example General: 123456
period	Σ	0..1	Period	Time period when id is/was valid for use
assigner	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)
clinicalStatus	?!SΣC	0..1	CodeableConcept	active | inactive | resolved Binding: AllergyIntoleranceClinicalStatusCodes (required): The clinical status of the allergy or intolerance.
verificationStatus	?!SΣC	1..1	CodeableConcept	unconfirmed | confirmed | refuted | entered-in-error Binding: AllergyIntoleranceVerificationStatusCodes (required): Assertion about certainty associated with a propensity, or potential risk, of a reaction to the identified substance.
type	SΣ	0..1	code	allergy | intolerance - Underlying mechanism (if known) Binding: AllergyIntoleranceType (required): Identification of the underlying physiological mechanism for a Reaction Risk.
category	SΣ	0..*	code	food | medication | environment | biologic Binding: AllergyIntoleranceCategory (required): Category of an identified substance associated with allergies or intolerances.
criticality	SΣ	0..1	code	low | high | unable-to-assess Binding: AllergyIntoleranceCriticality (required): Estimate of the potential clinical harm, or seriousness, of a reaction to an identified substance.
code	SΣ	1..1	CodeableConcept	Code that identifies the allergy or intolerance Binding: AllergyIntoleranceSubstance/Product,ConditionAndNegationCodes (example): Type of the substance/product, allergy or intolerance condition, or negation/exclusion codes for reporting no known allergies.
patient	SΣ	1..1	Reference(ANC Patient)	Who the sensitivity is for
encounter	S	0..1	Reference(ANC Encounter)	Encounter when the allergy or intolerance was asserted
onset[x]		0..1		When allergy or intolerance was identified
onsetDateTime			dateTime
onsetAge			Age
onsetPeriod			Period
onsetRange			Range
recordedDate	S	0..1	dateTime	Date first version of the resource instance was recorded
recorder	S	0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Who recorded the sensitivity
asserter	SΣ	0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Source of the information about the allergy
lastOccurrence		0..1	dateTime	Date(/time) of last known occurrence of a reaction
note		0..*	Annotation	Additional text not captured in other fields
reaction	S	0..*	BackboneElement	Adverse Reaction Events linked to exposure to substance
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
reaction-duration	S	0..1	Duration	How long Manifestations persisted URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-duration
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
substance		0..1	CodeableConcept	Specific substance or pharmaceutical product considered to be responsible for event Binding: SubstanceCode (example): Codes defining the type of the substance (including pharmaceutical products).
manifestation	S	1..*	CodeableConcept	Clinical symptoms/signs associated with the Event Binding: SNOMEDCTClinicalFindings (example): Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction Event.
description		0..1	string	Description of the event as a whole
onset	S	0..1	dateTime	Date(/time) when manifestations showed
severity	S	0..1	code	mild | moderate | severe (of event as a whole) Binding: AllergyIntoleranceSeverity (required): Clinical assessment of the severity of a reaction event as a whole, potentially considering multiple different manifestations.
exposureRoute		0..1	CodeableConcept	How the subject was exposed to the substance Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
note		0..*	Annotation	Text about event not captured in other fields
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
AllergyIntolerance.language	preferred	CommonLanguages Additional Bindings Purpose AllLanguages Max Binding http://hl7.org/fhir/ValueSet/languages from the FHIR Standard
AllergyIntolerance.identifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|4.0.1 from the FHIR Standard
AllergyIntolerance.identifier.type	extensible	Identifier Type Codes http://hl7.org/fhir/ValueSet/identifier-type from the FHIR Standard
AllergyIntolerance.clinicalStatus	required	AllergyIntoleranceClinicalStatusCodes http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|4.0.1 from the FHIR Standard
AllergyIntolerance.verificationStatus	required	AllergyIntoleranceVerificationStatusCodes http://hl7.org/fhir/ValueSet/allergyintolerance-verification|4.0.1 from the FHIR Standard
AllergyIntolerance.type	required	AllergyIntoleranceType http://hl7.org/fhir/ValueSet/allergy-intolerance-type|4.0.1 from the FHIR Standard
AllergyIntolerance.category	required	AllergyIntoleranceCategory http://hl7.org/fhir/ValueSet/allergy-intolerance-category|4.0.1 from the FHIR Standard
AllergyIntolerance.criticality	required	AllergyIntoleranceCriticality http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|4.0.1 from the FHIR Standard
AllergyIntolerance.code	example	AllergyIntoleranceSubstance/Product,ConditionAndNegationCodes http://hl7.org/fhir/ValueSet/allergyintolerance-code from the FHIR Standard
AllergyIntolerance.reaction.substance	example	SubstanceCode http://hl7.org/fhir/ValueSet/substance-code from the FHIR Standard
AllergyIntolerance.reaction.manifestation	example	SNOMEDCTClinicalFindings http://hl7.org/fhir/ValueSet/clinical-findings from the FHIR Standard
AllergyIntolerance.reaction.severity	required	AllergyIntoleranceSeverity http://hl7.org/fhir/ValueSet/reaction-event-severity|4.0.1 from the FHIR Standard
AllergyIntolerance.reaction.exposureRoute	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
1	error	AllergyIntolerance	extension: reasonRefuted is only permitted if status is refuted : verificationStatus.coding.code = 'refuted' or extension.where(url='http://hl7.org/fhir/StructureDefinition/allergyintolerance-reasonRefuted').empty()
ait-1	error	AllergyIntolerance	AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error. : verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').exists() or clinicalStatus.exists()
ait-2	error	AllergyIntolerance	AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error : verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').empty() or clinicalStatus.empty()
dom-2	error	AllergyIntolerance	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	AllergyIntolerance	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	AllergyIntolerance	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	AllergyIntolerance	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	AllergyIntolerance	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

This structure is derived from WHOAllergyIntolerance

Summary

Structures

This structure refers to these other structures:

• ANC Patient (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-patient)
• ANC Encounter (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-encounter)
• ANC Practitioner (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-practitioner)
• ANC PractitionerRole (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-practitionerrole)
• ANC RelatedPerson (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-relatedperson)

Differential View

This structure is derived from WHOAllergyIntolerance

Name	Flags	Card.	Type	Description & Constraints
AllergyIntolerance		0..*	WHOAllergyIntolerance	Allergy or Intolerance (generally: Risk of adverse reaction to a substance)
patient		1..1	Reference(ANC Patient)	Who the sensitivity is for
encounter		0..1	Reference(ANC Encounter)	Encounter when the allergy or intolerance was asserted
recorder		0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Who recorded the sensitivity
asserter		0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Source of the information about the allergy
Documentation for this format

Key Elements View

Name	Flags	Card.	Type	Description & Constraints
AllergyIntolerance	C	0..*	WHOAllergyIntolerance	Allergy or Intolerance (generally: Risk of adverse reaction to a substance) ait-1: AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error. ait-2: AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error 1: extension: reasonRefuted is only permitted if status is refuted
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
resolutionAge		0..1	Age	Age that the allergy or intolerance resolved URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-resolutionAge
reasonRefuted	SC	0..1	CodeableConcept	Explanation associated with refuted status URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-reasonRefuted
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..*	Identifier	External ids for this item
use	?!SΣ	1..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
system	SΣ	1..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient
value	SΣ	1..1	string	The value that is unique Example General: 123456
clinicalStatus	?!SΣC	0..1	CodeableConcept	active | inactive | resolved Binding: AllergyIntoleranceClinicalStatusCodes (required): The clinical status of the allergy or intolerance.
verificationStatus	?!SΣC	1..1	CodeableConcept	unconfirmed | confirmed | refuted | entered-in-error Binding: AllergyIntoleranceVerificationStatusCodes (required): Assertion about certainty associated with a propensity, or potential risk, of a reaction to the identified substance.
type	SΣ	0..1	code	allergy | intolerance - Underlying mechanism (if known) Binding: AllergyIntoleranceType (required): Identification of the underlying physiological mechanism for a Reaction Risk.
category	SΣ	0..*	code	food | medication | environment | biologic Binding: AllergyIntoleranceCategory (required): Category of an identified substance associated with allergies or intolerances.
criticality	SΣ	0..1	code	low | high | unable-to-assess Binding: AllergyIntoleranceCriticality (required): Estimate of the potential clinical harm, or seriousness, of a reaction to an identified substance.
code	SΣ	1..1	CodeableConcept	Code that identifies the allergy or intolerance Binding: AllergyIntoleranceSubstance/Product,ConditionAndNegationCodes (example): Type of the substance/product, allergy or intolerance condition, or negation/exclusion codes for reporting no known allergies.
patient	SΣ	1..1	Reference(ANC Patient)	Who the sensitivity is for
encounter	S	0..1	Reference(ANC Encounter)	Encounter when the allergy or intolerance was asserted
recordedDate	S	0..1	dateTime	Date first version of the resource instance was recorded
recorder	S	0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Who recorded the sensitivity
asserter	SΣ	0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Source of the information about the allergy
reaction	S	0..*	BackboneElement	Adverse Reaction Events linked to exposure to substance
reaction-duration	S	0..1	Duration	How long Manifestations persisted URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-duration
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
manifestation	S	1..*	CodeableConcept	Clinical symptoms/signs associated with the Event Binding: SNOMEDCTClinicalFindings (example): Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction Event.
onset	S	0..1	dateTime	Date(/time) when manifestations showed
severity	S	0..1	code	mild | moderate | severe (of event as a whole) Binding: AllergyIntoleranceSeverity (required): Clinical assessment of the severity of a reaction event as a whole, potentially considering multiple different manifestations.
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
AllergyIntolerance.identifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|4.0.1 from the FHIR Standard
AllergyIntolerance.clinicalStatus	required	AllergyIntoleranceClinicalStatusCodes http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|4.0.1 from the FHIR Standard
AllergyIntolerance.verificationStatus	required	AllergyIntoleranceVerificationStatusCodes http://hl7.org/fhir/ValueSet/allergyintolerance-verification|4.0.1 from the FHIR Standard
AllergyIntolerance.type	required	AllergyIntoleranceType http://hl7.org/fhir/ValueSet/allergy-intolerance-type|4.0.1 from the FHIR Standard
AllergyIntolerance.category	required	AllergyIntoleranceCategory http://hl7.org/fhir/ValueSet/allergy-intolerance-category|4.0.1 from the FHIR Standard
AllergyIntolerance.criticality	required	AllergyIntoleranceCriticality http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|4.0.1 from the FHIR Standard
AllergyIntolerance.code	example	AllergyIntoleranceSubstance/Product,ConditionAndNegationCodes http://hl7.org/fhir/ValueSet/allergyintolerance-code from the FHIR Standard
AllergyIntolerance.reaction.manifestation	example	SNOMEDCTClinicalFindings http://hl7.org/fhir/ValueSet/clinical-findings from the FHIR Standard
AllergyIntolerance.reaction.severity	required	AllergyIntoleranceSeverity http://hl7.org/fhir/ValueSet/reaction-event-severity|4.0.1 from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
1	error	AllergyIntolerance	extension: reasonRefuted is only permitted if status is refuted : verificationStatus.coding.code = 'refuted' or extension.where(url='http://hl7.org/fhir/StructureDefinition/allergyintolerance-reasonRefuted').empty()
ait-1	error	AllergyIntolerance	AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error. : verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').exists() or clinicalStatus.exists()
ait-2	error	AllergyIntolerance	AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error : verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').empty() or clinicalStatus.empty()
dom-2	error	AllergyIntolerance	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	AllergyIntolerance	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	AllergyIntolerance	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	AllergyIntolerance	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	AllergyIntolerance	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Snapshot View

Name	Flags	Card.	Type	Description & Constraints
AllergyIntolerance	C	0..*	WHOAllergyIntolerance	Allergy or Intolerance (generally: Risk of adverse reaction to a substance) ait-1: AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error. ait-2: AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error 1: extension: reasonRefuted is only permitted if status is refuted
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
resolutionAge		0..1	Age	Age that the allergy or intolerance resolved URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-resolutionAge
reasonRefuted	SC	0..1	CodeableConcept	Explanation associated with refuted status URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-reasonRefuted
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..*	Identifier	External ids for this item
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
use	?!SΣ	1..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
type	Σ	0..1	CodeableConcept	Description of identifier Binding: Identifier Type Codes (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.
system	SΣ	1..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient
value	SΣ	1..1	string	The value that is unique Example General: 123456
period	Σ	0..1	Period	Time period when id is/was valid for use
assigner	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)
clinicalStatus	?!SΣC	0..1	CodeableConcept	active | inactive | resolved Binding: AllergyIntoleranceClinicalStatusCodes (required): The clinical status of the allergy or intolerance.
verificationStatus	?!SΣC	1..1	CodeableConcept	unconfirmed | confirmed | refuted | entered-in-error Binding: AllergyIntoleranceVerificationStatusCodes (required): Assertion about certainty associated with a propensity, or potential risk, of a reaction to the identified substance.
type	SΣ	0..1	code	allergy | intolerance - Underlying mechanism (if known) Binding: AllergyIntoleranceType (required): Identification of the underlying physiological mechanism for a Reaction Risk.
category	SΣ	0..*	code	food | medication | environment | biologic Binding: AllergyIntoleranceCategory (required): Category of an identified substance associated with allergies or intolerances.
criticality	SΣ	0..1	code	low | high | unable-to-assess Binding: AllergyIntoleranceCriticality (required): Estimate of the potential clinical harm, or seriousness, of a reaction to an identified substance.
code	SΣ	1..1	CodeableConcept	Code that identifies the allergy or intolerance Binding: AllergyIntoleranceSubstance/Product,ConditionAndNegationCodes (example): Type of the substance/product, allergy or intolerance condition, or negation/exclusion codes for reporting no known allergies.
patient	SΣ	1..1	Reference(ANC Patient)	Who the sensitivity is for
encounter	S	0..1	Reference(ANC Encounter)	Encounter when the allergy or intolerance was asserted
onset[x]		0..1		When allergy or intolerance was identified
onsetDateTime			dateTime
onsetAge			Age
onsetPeriod			Period
onsetRange			Range
recordedDate	S	0..1	dateTime	Date first version of the resource instance was recorded
recorder	S	0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Who recorded the sensitivity
asserter	SΣ	0..1	Reference(ANC Practitioner | ANC PractitionerRole | ANC Patient | ANC RelatedPerson)	Source of the information about the allergy
lastOccurrence		0..1	dateTime	Date(/time) of last known occurrence of a reaction
note		0..*	Annotation	Additional text not captured in other fields
reaction	S	0..*	BackboneElement	Adverse Reaction Events linked to exposure to substance
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
reaction-duration	S	0..1	Duration	How long Manifestations persisted URL: http://hl7.org/fhir/StructureDefinition/allergyintolerance-duration
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
substance		0..1	CodeableConcept	Specific substance or pharmaceutical product considered to be responsible for event Binding: SubstanceCode (example): Codes defining the type of the substance (including pharmaceutical products).
manifestation	S	1..*	CodeableConcept	Clinical symptoms/signs associated with the Event Binding: SNOMEDCTClinicalFindings (example): Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction Event.
description		0..1	string	Description of the event as a whole
onset	S	0..1	dateTime	Date(/time) when manifestations showed
severity	S	0..1	code	mild | moderate | severe (of event as a whole) Binding: AllergyIntoleranceSeverity (required): Clinical assessment of the severity of a reaction event as a whole, potentially considering multiple different manifestations.
exposureRoute		0..1	CodeableConcept	How the subject was exposed to the substance Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
note		0..*	Annotation	Text about event not captured in other fields
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
AllergyIntolerance.language	preferred	CommonLanguages Additional Bindings Purpose AllLanguages Max Binding http://hl7.org/fhir/ValueSet/languages from the FHIR Standard
AllergyIntolerance.identifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|4.0.1 from the FHIR Standard
AllergyIntolerance.identifier.type	extensible	Identifier Type Codes http://hl7.org/fhir/ValueSet/identifier-type from the FHIR Standard
AllergyIntolerance.clinicalStatus	required	AllergyIntoleranceClinicalStatusCodes http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|4.0.1 from the FHIR Standard
AllergyIntolerance.verificationStatus	required	AllergyIntoleranceVerificationStatusCodes http://hl7.org/fhir/ValueSet/allergyintolerance-verification|4.0.1 from the FHIR Standard
AllergyIntolerance.type	required	AllergyIntoleranceType http://hl7.org/fhir/ValueSet/allergy-intolerance-type|4.0.1 from the FHIR Standard
AllergyIntolerance.category	required	AllergyIntoleranceCategory http://hl7.org/fhir/ValueSet/allergy-intolerance-category|4.0.1 from the FHIR Standard
AllergyIntolerance.criticality	required	AllergyIntoleranceCriticality http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|4.0.1 from the FHIR Standard
AllergyIntolerance.code	example	AllergyIntoleranceSubstance/Product,ConditionAndNegationCodes http://hl7.org/fhir/ValueSet/allergyintolerance-code from the FHIR Standard
AllergyIntolerance.reaction.substance	example	SubstanceCode http://hl7.org/fhir/ValueSet/substance-code from the FHIR Standard
AllergyIntolerance.reaction.manifestation	example	SNOMEDCTClinicalFindings http://hl7.org/fhir/ValueSet/clinical-findings from the FHIR Standard
AllergyIntolerance.reaction.severity	required	AllergyIntoleranceSeverity http://hl7.org/fhir/ValueSet/reaction-event-severity|4.0.1 from the FHIR Standard
AllergyIntolerance.reaction.exposureRoute	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
1	error	AllergyIntolerance	extension: reasonRefuted is only permitted if status is refuted : verificationStatus.coding.code = 'refuted' or extension.where(url='http://hl7.org/fhir/StructureDefinition/allergyintolerance-reasonRefuted').empty()
ait-1	error	AllergyIntolerance	AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error. : verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').exists() or clinicalStatus.exists()
ait-2	error	AllergyIntolerance	AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error : verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').empty() or clinicalStatus.empty()
dom-2	error	AllergyIntolerance	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	AllergyIntolerance	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	AllergyIntolerance	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	AllergyIntolerance	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	AllergyIntolerance	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

This structure is derived from WHOAllergyIntolerance

Summary

Structures

This structure refers to these other structures:

• ANC Patient (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-patient)
• ANC Encounter (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-encounter)
• ANC Practitioner (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-practitioner)
• ANC PractitionerRole (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-practitionerrole)
• ANC RelatedPerson (http://fhir.org/guides/who/anc-cds/StructureDefinition/anc-relatedperson)

Other representations of profile: CSV, Excel, Schematron