Response to Regulatory Questions (RTQ)
0.1.0 - ci-build

Response to Regulatory Questions (RTQ), published by HL7 International. This guide is not an authorized publication; it is the continuous build for version 0.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/rtq-ig/ and changes regularly. See the Directory of published versions

Question Profile & Example

This page provides a technical outline of the Regulatory Questionnaire profile structure. Built on HL7 FHIR R5, this resource enables the structured, machine-readable exchange of regulatory questions while preserving rich formatting and traceability to the Common Technical Document (CTD) structure.


Example

View the example below:


Key Elements of a Regulatory Question

The following table maps the technical components of a regulatory question to their implementation in the RTQ Questionnaire profile. This breakdown details the required data structures for CTD section mapping, rich-text rendering, and participant identification.

Element Cardinality Purpose / Notes
meta.profile 1..1 Fixed to http://hl7.org/fhir/uv/rtq/StructureDefinition/rtq-questionnaire to ensure conformance and API routing.
identifier 1..2 Unique IDs. Slices: regulator-id (Mandatory) and company-id (Optional).
version 1..1 The business version of the questionnaire set (e.g., "1.0").
text 1..1 Human-readable narrative (XHTML) containing the summary of the question set.
subjectType 1..* Coded context of the regulatory procedure (e.g., variation-type-ii).
contact (SENDER) 1..1 Issuing health authority (Regulator) with full organizational IDs, address, and primary contact info.
contact (RECEIVER) 1..1 The pharmaceutical MAH or applicant expected to respond.
item.code 1..* Mandatory CTD section mapping (e.g., 3.2.P.8.1) using the RTQ CTD Categories CodeSystem.
item.text 1..1 The question text. Requires the rendering-xhtml extension for formatted content like tables or lists.