Genomics Reporting Implementation Guide, published by HL7 International / Clinical Genomics. This guide is not an authorized publication; it is the continuous build for version 4.0.0-cibuild built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/genomics-reporting/ and changes regularly. See the Directory of published versions
: PGxRecEx05 - TTL Representation
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@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
# - resource -------------------------------------------------------------------
<http://hl7.org/fhir/Task/PGxRecEx05> a fhir:Task ;
fhir:nodeRole fhir:treeRoot ;
fhir:Resource.id [ fhir:value "PGxRecEx05"] ;
fhir:Resource.meta [
fhir:Meta.profile [
fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/followup-recommendation" ;
fhir:index 0 ;
fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/followup-recommendation>
]
] ;
fhir:DomainResource.text [
fhir:Narrative.status [ fhir:value "generated" ] ;
fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Task PGxRecEx05</b></p><a name=\"PGxRecEx05\"> </a><a name=\"hcPGxRecEx05\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-followup-recommendation.html\">Followup Recommendation</a></p></div><p><b>status</b>: Requested</p><p><b>intent</b>: proposal</p><p><b>code</b>: <span title=\"Codes:{http://loinc.org LA26422-8}\">Decrease dose</span></p><p><b>description</b>: For amitriptyline, a 50% reduction in starting dose is recommended with therapeutic drug monitoring to guide dose adjustment. Refer to current guidelines for dosage and recommendations at https://cpicpgx.org/guidelines/guideline-for- tricyclic-antidepressants-and-cyp2d6-and-cyp2c19/. If CYP2D6 genotyping is available, refer to the current guidelines for dosing recommendations.</p><p><b>for</b>: <a href=\"Patient-CGPatientExample01.html\">Adam B. Everyman Male, DoB: 1951-01-20 ( Medical Record Number: m123 (use: usual, ))</a></p><p><b>reasonReference</b>: <a href=\"Observation-TxImp05.html\">Poor metabolizer</a></p></div>"
] ;
fhir:Task.status [ fhir:value "requested"] ;
fhir:Task.intent [ fhir:value "proposal"] ;
fhir:Task.code [
fhir:CodeableConcept.coding [
fhir:index 0 ;
a loinc:LA26422-8 ;
fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
fhir:Coding.code [ fhir:value "LA26422-8" ] ;
fhir:Coding.display [ fhir:value "Decrease dose" ]
]
] ;
fhir:Task.description [ fhir:value "For amitriptyline, a 50% reduction in starting dose is recommended with therapeutic drug monitoring to guide dose adjustment. Refer to current guidelines for dosage and recommendations at https://cpicpgx.org/guidelines/guideline-for- tricyclic-antidepressants-and-cyp2d6-and-cyp2c19/. If CYP2D6 genotyping is available, refer to the current guidelines for dosing recommendations."] ;
fhir:Task.for [
fhir:link <http://hl7.org/fhir/Patient/CGPatientExample01> ;
fhir:Reference.reference [ fhir:value "Patient/CGPatientExample01" ]
] ;
fhir:Task.reasonReference [
fhir:link <http://hl7.org/fhir/Observation/TxImp05> ;
fhir:Reference.reference [ fhir:value "Observation/TxImp05" ] ;
fhir:Reference.display [ fhir:value "Poor metabolizer" ]
] .
<http://hl7.org/fhir/Patient/CGPatientExample01> a fhir:Patient .
<http://hl7.org/fhir/Observation/TxImp05> a fhir:Observation .
# - ontology header ------------------------------------------------------------
<http://hl7.org/fhir/Task/PGxRecEx05.ttl> a owl:Ontology ;
owl:imports fhir:fhir.ttl ;
owl:versionIRI <http://build.fhir.org/Task/PGxRecEx05.ttl> .
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