minimal Common Oncology Data Elements (mCODE) Implementation Guide
4.0.0-ballot - ballot United States of America flag

minimal Common Oncology Data Elements (mCODE) Implementation Guide, published by HL7 International / Clinical Interoperability Council. This guide is not an authorized publication; it is the continuous build for version 4.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/fhir-mCODE-ig/ and changes regularly. See the Directory of published versions

Resource Profile: Genomic Region Studied Profile

Official URL: http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-genomic-region-studied Version: 4.0.0-ballot
Active as of 2024-03-26 Maturity Level: 1 Computable Name: GenomicRegionStudied
Other Identifiers: OID:2.16.840.1.113883.4.642.40.15.42.18

A subset of genes or genomic regions of interest in a targeted resequencing study.

Usage

This profile identifies a specific region analyzed for gene mutations or variants in a given genomic test. For example, exome sequencing tests could analyze multiple non-contiguous regions. Each region is designated by a range of start and end location and referencing a coordinate system which is 0-based or 1-based.

RegionStudied is noted at the GenomicsReport level and not directly tied to a given GenomicVariant.

Conformance

Observation resources associated with an in-scope patient with DiagnosticReport.code LOINC 53041-0 SHALL conform to this profile. Beyond this requirement, a producer of resources SHOULD ensure that any resource instance associated with an in-scope patient that would reasonably be expected to conform to this profile SHOULD be published in this form.

Usage:

Changes since version true:

  • No changes
  • Formal Views of Profile Content

    Description of Profiles, Differentials, Snapshots and how the different presentations work.

    This structure is derived from RegionStudied

    NameFlagsCard.TypeDescription & Constraintsdoco
    .. Observation 0..*RegionStudiedRegion Studied
    ... status S1..1coderegistered | preliminary | final | amended +
    ... category S1..*CodeableConceptClassification of type of observation
    ... category:labCategory 1..1CodeableConceptClassification of type of observation
    Required Pattern: At least the following
    .... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ..... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ..... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    .... coding 1..1CodingCode defined by a terminology system
    ... subject S1..1Reference(Cancer Patient Profile)Who and/or what the observation is about
    ... Slices for effective[x] S0..1dateTime, Period, Timing, instantClinically relevant time/time-period for observation
    Slice: Unordered, Open by type:$this
    .... effective[x]:effectiveDateTime S0..1dateTimeClinically relevant time/time-period for observation
    ... value[x] 0..0Quantity, CodeableConcept, string, boolean, integer, Range, Ratio, SampledData, time, dateTime, Period
    ... dataAbsentReason S0..1CodeableConceptWhy the result is missing
    ... component S0..*BackboneElementComponent results
    ... component:gene-studied S0..1BackboneElementGene Studied
    .... code S1..1CodeableConcept48018-6
    .... value[x] S1..1CodeableConceptThe HGNC gene symbol is to be used as display text and the HGNC gene ID used as the code. If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used.
    ... component:gene-mutations S0..1BackboneElementGene Mutations ID
    .... code S1..1CodeableConcept36908-2
    .... value[x] S1..1CodeableConceptActual component result
    ... component:region-description S0..1BackboneElementRegion Description
    .... code S1..1CodeableConcept81293-3
    .... value[x] S0..1stringActual component result
    ... component:ranges-examined S0..*BackboneElementRange(s) of DNA sequence examined
    .... code S1..1CodeableConcept51959-5
    .... value[x] S0..1RangeActual component result
    ... component:coordinate-system S0..1BackboneElementCoordinate System
    .... code S1..1CodeableConcept92822-6
    .... value[x] S1..1CodeableConcept0-based interval counting | 0-based character counting | 1-based character counting
    ... component:genomic-ref-seq S0..1BackboneElementGenomic Reference Sequence
    .... code S1..1CodeableConcept48013-7
    .... value[x] S1..1CodeableConceptVersioned genomic reference sequence identifier.

    doco Documentation for this format
    NameFlagsCard.TypeDescription & Constraintsdoco
    .. Observation C0..*RegionStudiedRegion Studied
    obs-6: dataAbsentReason SHALL only be present if Observation.value[x] is not present
    obs-7: If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present
    ... implicitRules ?!Σ0..1uriA set of rules under which this content was created
    ... secondary-finding 0..1CodeableConceptSecondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when [Whole Exome Sequencing (WES)](https://en.wikipedia.org/wiki/Exome_sequencing) or [Whole Genome Sequencing (WGS)](https://en.wikipedia.org/wiki/Whole_genome_sequencing) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement. For more detail, please see: https://ghr.nlm.nih.gov/primer/testing/secondaryfindings
    URL: http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding
    Binding: GeneticObservationSecondaryFindings (extensible): Codes to denote a guideline or policy statement when a genetic test result is being shared as a secondary finding.


    ... body-structure 0..1Reference(BodyStructure)Target anatomic location or structure
    URL: http://hl7.org/fhir/StructureDefinition/bodySite
    ... status ?!SΣ1..1coderegistered | preliminary | final | amended +
    Binding: ObservationStatus (required): Codes providing the status of an observation.

    ... Slices for category S1..*CodeableConceptClassification of type of observation
    Slice: Unordered, Open by value:coding
    Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.


    .... category:labCategory 1..1CodeableConceptClassification of type of observation
    Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.



    Required Pattern: At least the following
    ..... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ...... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ...... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    ..... coding Σ1..1CodingCode defined by a terminology system

    Required Pattern: At least the following
    ...... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ...... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    ... code SΣ1..1CodeableConcept53041-0
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    .... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ..... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ..... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 53041-0
    ... subject SΣ1..1Reference(Cancer Patient Profile)Who and/or what the observation is about
    ... Slices for effective[x] SΣ0..1Clinically relevant time/time-period for observation
    Slice: Unordered, Open by type:$this
    .... effectiveDateTimedateTime
    .... effectivePeriodPeriod
    .... effectiveTimingTiming
    .... effectiveInstantinstant
    .... effective[x]:effectiveDateTime SΣ0..1dateTimeClinically relevant time/time-period for observation
    ... dataAbsentReason SC0..1CodeableConceptWhy the result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ... Slices for component SΣ0..*BackboneElementComponent results
    Slice: Unordered, Open by pattern:code
    .... component:All Slices Content/Rules for all slices
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptType of component observation (code / type)
    Binding: LOINCCodes (example): Codes identifying names of simple observations.

    .... component:conclusion-string Σ0..1BackboneElementClinical Conclusion
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptconclusion-string
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: conclusion-string
    .... component:gene-studied SΣ0..1BackboneElementGene Studied
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept48018-6
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 48018-6
    ..... value[x] SΣ1..1CodeableConceptThe HGNC gene symbol is to be used as display text and the HGNC gene ID used as the code. If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used.
    Binding: HUGO Gene Nomenclature Committee Gene Names (HGNC) (extensible)
    .... component:gene-mutations SΣ0..1BackboneElementGene Mutations ID
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept36908-2
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 36908-2
    ..... value[x] SΣ1..1CodeableConceptActual component result
    Binding: Human Genome Variation Society (HGVS) Nomenclature (required)
    .... component:region-description SΣ0..1BackboneElementRegion Description
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept81293-3
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 81293-3
    ..... value[x] SΣ0..1stringActual component result
    .... component:region-coverage Σ0..1BackboneElementRegion Coverage
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptregion-coverage
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: region-coverage
    .... component:ranges-examined SΣ0..*BackboneElementRange(s) of DNA sequence examined
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept51959-5
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 51959-5
    ..... value[x] SΣ0..1RangeActual component result
    .... component:coordinate-system SΣ0..1BackboneElementCoordinate System
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept92822-6
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 92822-6
    ..... value[x] SΣ1..1CodeableConcept0-based interval counting | 0-based character counting | 1-based character counting
    Binding: LOINC Answer List LL5323-2 (extensible)
    .... component:genomic-ref-seq SΣ0..1BackboneElementGenomic Reference Sequence
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept48013-7
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 48013-7
    ..... value[x] SΣ1..1CodeableConceptVersioned genomic reference sequence identifier.
    Binding: (unbound) (example): Multiple bindings acceptable (NCBI or LRG)

    .... component:uncallable-regions Σ0..*BackboneElementUncallable Sub-regions
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptuncallable-regions
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: uncallable-regions

    doco Documentation for this format

    Terminology Bindings

    PathConformanceValueSet / CodeURI
    Observation.statusrequiredObservationStatus
    http://hl7.org/fhir/ValueSet/observation-status|4.0.1
    from the FHIR Standard
    Observation.categorypreferredObservationCategoryCodes
    http://hl7.org/fhir/ValueSet/observation-category
    from the FHIR Standard
    Observation.category:labCategorypreferredPattern: laboratory
    http://hl7.org/fhir/ValueSet/observation-category
    from the FHIR Standard
    Observation.codeexamplePattern: LOINC code 53041-0
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component.codeexampleLOINCCodes (a valid code from LOINC)
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:conclusion-string.codeexamplePattern: conclusion-string
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-studied.codeexamplePattern: LOINC code 48018-6
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-studied.value[x]extensibleHGNCVS
    http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs
    Observation.component:gene-mutations.codeexamplePattern: LOINC code 36908-2
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-mutations.value[x]requiredHGVSVS
    http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs
    Observation.component:region-description.codeexamplePattern: LOINC code 81293-3
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:region-coverage.codeexamplePattern: region-coverage
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:ranges-examined.codeexamplePattern: LOINC code 51959-5
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:coordinate-system.codeexamplePattern: LOINC code 92822-6
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:coordinate-system.value[x]extensibleLOINC LL5323-2
    http://loinc.org/vs/LL5323-2
    Observation.component:genomic-ref-seq.codeexamplePattern: LOINC code 48013-7
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:genomic-ref-seq.value[x]example
    Observation.component:uncallable-regions.codeexamplePattern: uncallable-regions
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    NameFlagsCard.TypeDescription & Constraintsdoco
    .. Observation C0..*RegionStudiedRegion Studied
    obs-6: dataAbsentReason SHALL only be present if Observation.value[x] is not present
    obs-7: If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present
    ... id Σ0..1idLogical id of this artifact
    ... meta Σ0..1MetaMetadata about the resource
    ... implicitRules ?!Σ0..1uriA set of rules under which this content was created
    ... language 0..1codeLanguage of the resource content
    Binding: CommonLanguages (preferred): A human language.

    Additional BindingsPurpose
    AllLanguagesMax Binding
    ... text 0..1NarrativeText summary of the resource, for human interpretation
    ... contained 0..*ResourceContained, inline Resources
    ... Slices for extension 0..*ExtensionExtension
    Slice: Unordered, Open by value:url
    ... secondary-finding 0..1CodeableConceptSecondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when [Whole Exome Sequencing (WES)](https://en.wikipedia.org/wiki/Exome_sequencing) or [Whole Genome Sequencing (WGS)](https://en.wikipedia.org/wiki/Whole_genome_sequencing) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement. For more detail, please see: https://ghr.nlm.nih.gov/primer/testing/secondaryfindings
    URL: http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding
    Binding: GeneticObservationSecondaryFindings (extensible): Codes to denote a guideline or policy statement when a genetic test result is being shared as a secondary finding.


    ... body-structure 0..1Reference(BodyStructure)Target anatomic location or structure
    URL: http://hl7.org/fhir/StructureDefinition/bodySite
    ... modifierExtension ?!0..*ExtensionExtensions that cannot be ignored
    ... identifier Σ0..*IdentifierBusiness Identifier for observation
    ... basedOn Σ0..*Reference(CarePlan | DeviceRequest | ImmunizationRecommendation | MedicationRequest | NutritionOrder | ServiceRequest)Fulfills plan, proposal or order
    ... partOf Σ0..*Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Immunization | ImagingStudy)Part of referenced event
    ... status ?!SΣ1..1coderegistered | preliminary | final | amended +
    Binding: ObservationStatus (required): Codes providing the status of an observation.

    ... Slices for category S1..*CodeableConceptClassification of type of observation
    Slice: Unordered, Open by value:coding
    Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.


    .... category:labCategory 1..1CodeableConceptClassification of type of observation
    Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.



    Required Pattern: At least the following
    ..... id0..1stringUnique id for inter-element referencing
    ..... extension0..*ExtensionAdditional content defined by implementations
    ..... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ...... version0..1stringVersion of the system - if relevant
    ...... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    ...... display0..1stringRepresentation defined by the system
    ...... userSelected0..1booleanIf this coding was chosen directly by the user
    ..... text0..1stringPlain text representation of the concept
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    Slice: Unordered, Open by value:url
    ..... coding Σ1..1CodingCode defined by a terminology system

    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ...... version0..1stringVersion of the system - if relevant
    ...... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    ...... display0..1stringRepresentation defined by the system
    ...... userSelected0..1booleanIf this coding was chosen directly by the user
    ..... text Σ0..1stringPlain text representation of the concept
    ... code SΣ1..1CodeableConcept53041-0
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    .... id0..1stringUnique id for inter-element referencing
    .... extension0..*ExtensionAdditional content defined by implementations
    .... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ..... id0..1stringUnique id for inter-element referencing
    ..... extension0..*ExtensionAdditional content defined by implementations
    ..... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ..... version0..1stringVersion of the system - if relevant
    ..... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 53041-0
    ..... display0..1stringRepresentation defined by the system
    ..... userSelected0..1booleanIf this coding was chosen directly by the user
    .... text0..1stringPlain text representation of the concept
    ... subject SΣ1..1Reference(Cancer Patient Profile)Who and/or what the observation is about
    ... focus Σ0..*Reference(Resource)What the observation is about, when it is not about the subject of record
    ... encounter Σ0..1Reference(Encounter)Healthcare event during which this observation is made
    ... Slices for effective[x] SΣ0..1Clinically relevant time/time-period for observation
    Slice: Unordered, Open by type:$this
    .... effectiveDateTimedateTime
    .... effectivePeriodPeriod
    .... effectiveTimingTiming
    .... effectiveInstantinstant
    .... effective[x]:effectiveDateTime SΣ0..1dateTimeClinically relevant time/time-period for observation
    ... issued Σ0..1instantDate/Time this version was made available
    ... performer Σ0..*Reference(Practitioner | PractitionerRole | Organization | CareTeam | Patient | RelatedPerson)Who is responsible for the observation
    ... dataAbsentReason SC0..1CodeableConceptWhy the result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ... note 0..*CodedAnnotationComments about the Observation that also contain a coded type
    ... bodySite 0..1CodeableConceptObserved body part
    Binding: SNOMEDCTBodyStructures (example): Codes describing anatomical locations. May include laterality.

    ... method 0..1CodeableConceptHow it was done
    Binding: ObservationMethods (example): Methods for simple observations.

    ... specimen 0..1Reference(Specimen)Specimen used for this observation
    ... device 0..1Reference(Device | DeviceMetric)(Measurement) Device
    ... referenceRange C0..*BackboneElementProvides guide for interpretation
    obs-3: Must have at least a low or a high or text
    .... id 0..1stringUnique id for inter-element referencing
    .... extension 0..*ExtensionAdditional content defined by implementations
    .... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    .... low C0..1SimpleQuantityLow Range, if relevant
    .... high C0..1SimpleQuantityHigh Range, if relevant
    .... type 0..1CodeableConceptReference range qualifier
    Binding: ObservationReferenceRangeMeaningCodes (preferred): Code for the meaning of a reference range.

    .... appliesTo 0..*CodeableConceptReference range population
    Binding: ObservationReferenceRangeAppliesToCodes (example): Codes identifying the population the reference range applies to.


    .... age 0..1RangeApplicable age range, if relevant
    .... text 0..1stringText based reference range in an observation
    ... hasMember Σ0..*Reference(Observation | QuestionnaireResponse | MolecularSequence)Related resource that belongs to the Observation group
    ... derivedFrom Σ0..*Reference(DocumentReference | ImagingStudy | Media | QuestionnaireResponse | Observation | MolecularSequence)Related measurements the observation is made from
    ... Slices for component SΣ0..*BackboneElementComponent results
    Slice: Unordered, Open by pattern:code
    .... component:All Slices Content/Rules for all slices
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptType of component observation (code / type)
    Binding: LOINCCodes (example): Codes identifying names of simple observations.

    ..... value[x] Σ0..1Actual component result
    ...... valueQuantityQuantity
    ...... valueCodeableConceptCodeableConcept
    ...... valueStringstring
    ...... valueBooleanboolean
    ...... valueIntegerinteger
    ...... valueRangeRange
    ...... valueRatioRatio
    ...... valueSampledDataSampledData
    ...... valueTimetime
    ...... valueDateTimedateTime
    ...... valuePeriodPeriod
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:conclusion-string Σ0..1BackboneElementClinical Conclusion
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptconclusion-string
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: conclusion-string
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] Σ0..1stringSummary conclusion (interpretation/impression)
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:gene-studied SΣ0..1BackboneElementGene Studied
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept48018-6
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 48018-6
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ1..1CodeableConceptThe HGNC gene symbol is to be used as display text and the HGNC gene ID used as the code. If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used.
    Binding: HUGO Gene Nomenclature Committee Gene Names (HGNC) (extensible)
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:gene-mutations SΣ0..1BackboneElementGene Mutations ID
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept36908-2
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 36908-2
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ1..1CodeableConceptActual component result
    Binding: Human Genome Variation Society (HGVS) Nomenclature (required)
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:region-description SΣ0..1BackboneElementRegion Description
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept81293-3
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 81293-3
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ0..1stringActual component result
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:region-coverage Σ0..1BackboneElementRegion Coverage
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptregion-coverage
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: region-coverage
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] Σ0..1QuantityActual component result
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:ranges-examined SΣ0..*BackboneElementRange(s) of DNA sequence examined
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept51959-5
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 51959-5
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ0..1RangeActual component result
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:coordinate-system SΣ0..1BackboneElementCoordinate System
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept92822-6
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 92822-6
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ1..1CodeableConcept0-based interval counting | 0-based character counting | 1-based character counting
    Binding: LOINC Answer List LL5323-2 (extensible)
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:genomic-ref-seq SΣ0..1BackboneElementGenomic Reference Sequence
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept48013-7
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 48013-7
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ1..1CodeableConceptVersioned genomic reference sequence identifier.
    Binding: (unbound) (example): Multiple bindings acceptable (NCBI or LRG)

    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:uncallable-regions Σ0..*BackboneElementUncallable Sub-regions
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptuncallable-regions
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: uncallable-regions
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] Σ0..1RangeMust be inside the range given by 'ranges examined' in the given reference sequence and coordinate system.
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result

    doco Documentation for this format

    Terminology Bindings

    PathConformanceValueSet / CodeURI
    Observation.languagepreferredCommonLanguages
    Additional Bindings Purpose
    AllLanguages Max Binding
    http://hl7.org/fhir/ValueSet/languages
    from the FHIR Standard
    Observation.statusrequiredObservationStatus
    http://hl7.org/fhir/ValueSet/observation-status|4.0.1
    from the FHIR Standard
    Observation.categorypreferredObservationCategoryCodes
    http://hl7.org/fhir/ValueSet/observation-category
    from the FHIR Standard
    Observation.category:labCategorypreferredPattern: laboratory
    http://hl7.org/fhir/ValueSet/observation-category
    from the FHIR Standard
    Observation.codeexamplePattern: LOINC code 53041-0
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.bodySiteexampleSNOMEDCTBodyStructures
    http://hl7.org/fhir/ValueSet/body-site
    from the FHIR Standard
    Observation.methodexampleObservationMethods
    http://hl7.org/fhir/ValueSet/observation-methods
    from the FHIR Standard
    Observation.referenceRange.typepreferredObservationReferenceRangeMeaningCodes
    http://hl7.org/fhir/ValueSet/referencerange-meaning
    from the FHIR Standard
    Observation.referenceRange.appliesToexampleObservationReferenceRangeAppliesToCodes
    http://hl7.org/fhir/ValueSet/referencerange-appliesto
    from the FHIR Standard
    Observation.component.codeexampleLOINCCodes (a valid code from LOINC)
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:conclusion-string.codeexamplePattern: conclusion-string
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:conclusion-string.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:conclusion-string.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:gene-studied.codeexamplePattern: LOINC code 48018-6
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-studied.value[x]extensibleHGNCVS
    http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs
    Observation.component:gene-studied.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:gene-studied.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:gene-mutations.codeexamplePattern: LOINC code 36908-2
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-mutations.value[x]requiredHGVSVS
    http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs
    Observation.component:gene-mutations.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:gene-mutations.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:region-description.codeexamplePattern: LOINC code 81293-3
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:region-description.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:region-description.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:region-coverage.codeexamplePattern: region-coverage
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:region-coverage.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:region-coverage.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:ranges-examined.codeexamplePattern: LOINC code 51959-5
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:ranges-examined.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:ranges-examined.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:coordinate-system.codeexamplePattern: LOINC code 92822-6
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:coordinate-system.value[x]extensibleLOINC LL5323-2
    http://loinc.org/vs/LL5323-2
    Observation.component:coordinate-system.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:coordinate-system.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:genomic-ref-seq.codeexamplePattern: LOINC code 48013-7
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:genomic-ref-seq.value[x]example
    Observation.component:genomic-ref-seq.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:genomic-ref-seq.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:uncallable-regions.codeexamplePattern: uncallable-regions
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:uncallable-regions.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:uncallable-regions.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard

    This structure is derived from RegionStudied

    Summary

    Mandatory: 1 element
    Must-Support: 26 elements

    Structures

    This structure refers to these other structures:

    Slices

    This structure defines the following Slices:

    • The element Observation.effective[x] is sliced based on the value of type:$this

    Maturity: 1

    Differential View

    This structure is derived from RegionStudied

    NameFlagsCard.TypeDescription & Constraintsdoco
    .. Observation 0..*RegionStudiedRegion Studied
    ... status S1..1coderegistered | preliminary | final | amended +
    ... category S1..*CodeableConceptClassification of type of observation
    ... category:labCategory 1..1CodeableConceptClassification of type of observation
    Required Pattern: At least the following
    .... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ..... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ..... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    .... coding 1..1CodingCode defined by a terminology system
    ... subject S1..1Reference(Cancer Patient Profile)Who and/or what the observation is about
    ... Slices for effective[x] S0..1dateTime, Period, Timing, instantClinically relevant time/time-period for observation
    Slice: Unordered, Open by type:$this
    .... effective[x]:effectiveDateTime S0..1dateTimeClinically relevant time/time-period for observation
    ... value[x] 0..0Quantity, CodeableConcept, string, boolean, integer, Range, Ratio, SampledData, time, dateTime, Period
    ... dataAbsentReason S0..1CodeableConceptWhy the result is missing
    ... component S0..*BackboneElementComponent results
    ... component:gene-studied S0..1BackboneElementGene Studied
    .... code S1..1CodeableConcept48018-6
    .... value[x] S1..1CodeableConceptThe HGNC gene symbol is to be used as display text and the HGNC gene ID used as the code. If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used.
    ... component:gene-mutations S0..1BackboneElementGene Mutations ID
    .... code S1..1CodeableConcept36908-2
    .... value[x] S1..1CodeableConceptActual component result
    ... component:region-description S0..1BackboneElementRegion Description
    .... code S1..1CodeableConcept81293-3
    .... value[x] S0..1stringActual component result
    ... component:ranges-examined S0..*BackboneElementRange(s) of DNA sequence examined
    .... code S1..1CodeableConcept51959-5
    .... value[x] S0..1RangeActual component result
    ... component:coordinate-system S0..1BackboneElementCoordinate System
    .... code S1..1CodeableConcept92822-6
    .... value[x] S1..1CodeableConcept0-based interval counting | 0-based character counting | 1-based character counting
    ... component:genomic-ref-seq S0..1BackboneElementGenomic Reference Sequence
    .... code S1..1CodeableConcept48013-7
    .... value[x] S1..1CodeableConceptVersioned genomic reference sequence identifier.

    doco Documentation for this format

    Key Elements View

    NameFlagsCard.TypeDescription & Constraintsdoco
    .. Observation C0..*RegionStudiedRegion Studied
    obs-6: dataAbsentReason SHALL only be present if Observation.value[x] is not present
    obs-7: If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present
    ... implicitRules ?!Σ0..1uriA set of rules under which this content was created
    ... secondary-finding 0..1CodeableConceptSecondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when [Whole Exome Sequencing (WES)](https://en.wikipedia.org/wiki/Exome_sequencing) or [Whole Genome Sequencing (WGS)](https://en.wikipedia.org/wiki/Whole_genome_sequencing) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement. For more detail, please see: https://ghr.nlm.nih.gov/primer/testing/secondaryfindings
    URL: http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding
    Binding: GeneticObservationSecondaryFindings (extensible): Codes to denote a guideline or policy statement when a genetic test result is being shared as a secondary finding.


    ... body-structure 0..1Reference(BodyStructure)Target anatomic location or structure
    URL: http://hl7.org/fhir/StructureDefinition/bodySite
    ... status ?!SΣ1..1coderegistered | preliminary | final | amended +
    Binding: ObservationStatus (required): Codes providing the status of an observation.

    ... Slices for category S1..*CodeableConceptClassification of type of observation
    Slice: Unordered, Open by value:coding
    Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.


    .... category:labCategory 1..1CodeableConceptClassification of type of observation
    Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.



    Required Pattern: At least the following
    ..... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ...... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ...... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    ..... coding Σ1..1CodingCode defined by a terminology system

    Required Pattern: At least the following
    ...... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ...... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    ... code SΣ1..1CodeableConcept53041-0
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    .... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ..... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ..... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 53041-0
    ... subject SΣ1..1Reference(Cancer Patient Profile)Who and/or what the observation is about
    ... Slices for effective[x] SΣ0..1Clinically relevant time/time-period for observation
    Slice: Unordered, Open by type:$this
    .... effectiveDateTimedateTime
    .... effectivePeriodPeriod
    .... effectiveTimingTiming
    .... effectiveInstantinstant
    .... effective[x]:effectiveDateTime SΣ0..1dateTimeClinically relevant time/time-period for observation
    ... dataAbsentReason SC0..1CodeableConceptWhy the result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ... Slices for component SΣ0..*BackboneElementComponent results
    Slice: Unordered, Open by pattern:code
    .... component:All Slices Content/Rules for all slices
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptType of component observation (code / type)
    Binding: LOINCCodes (example): Codes identifying names of simple observations.

    .... component:conclusion-string Σ0..1BackboneElementClinical Conclusion
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptconclusion-string
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: conclusion-string
    .... component:gene-studied SΣ0..1BackboneElementGene Studied
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept48018-6
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 48018-6
    ..... value[x] SΣ1..1CodeableConceptThe HGNC gene symbol is to be used as display text and the HGNC gene ID used as the code. If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used.
    Binding: HUGO Gene Nomenclature Committee Gene Names (HGNC) (extensible)
    .... component:gene-mutations SΣ0..1BackboneElementGene Mutations ID
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept36908-2
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 36908-2
    ..... value[x] SΣ1..1CodeableConceptActual component result
    Binding: Human Genome Variation Society (HGVS) Nomenclature (required)
    .... component:region-description SΣ0..1BackboneElementRegion Description
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept81293-3
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 81293-3
    ..... value[x] SΣ0..1stringActual component result
    .... component:region-coverage Σ0..1BackboneElementRegion Coverage
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptregion-coverage
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: region-coverage
    .... component:ranges-examined SΣ0..*BackboneElementRange(s) of DNA sequence examined
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept51959-5
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 51959-5
    ..... value[x] SΣ0..1RangeActual component result
    .... component:coordinate-system SΣ0..1BackboneElementCoordinate System
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept92822-6
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 92822-6
    ..... value[x] SΣ1..1CodeableConcept0-based interval counting | 0-based character counting | 1-based character counting
    Binding: LOINC Answer List LL5323-2 (extensible)
    .... component:genomic-ref-seq SΣ0..1BackboneElementGenomic Reference Sequence
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept48013-7
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 48013-7
    ..... value[x] SΣ1..1CodeableConceptVersioned genomic reference sequence identifier.
    Binding: (unbound) (example): Multiple bindings acceptable (NCBI or LRG)

    .... component:uncallable-regions Σ0..*BackboneElementUncallable Sub-regions
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptuncallable-regions
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: uncallable-regions

    doco Documentation for this format

    Terminology Bindings

    PathConformanceValueSet / CodeURI
    Observation.statusrequiredObservationStatus
    http://hl7.org/fhir/ValueSet/observation-status|4.0.1
    from the FHIR Standard
    Observation.categorypreferredObservationCategoryCodes
    http://hl7.org/fhir/ValueSet/observation-category
    from the FHIR Standard
    Observation.category:labCategorypreferredPattern: laboratory
    http://hl7.org/fhir/ValueSet/observation-category
    from the FHIR Standard
    Observation.codeexamplePattern: LOINC code 53041-0
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component.codeexampleLOINCCodes (a valid code from LOINC)
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:conclusion-string.codeexamplePattern: conclusion-string
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-studied.codeexamplePattern: LOINC code 48018-6
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-studied.value[x]extensibleHGNCVS
    http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs
    Observation.component:gene-mutations.codeexamplePattern: LOINC code 36908-2
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-mutations.value[x]requiredHGVSVS
    http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs
    Observation.component:region-description.codeexamplePattern: LOINC code 81293-3
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:region-coverage.codeexamplePattern: region-coverage
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:ranges-examined.codeexamplePattern: LOINC code 51959-5
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:coordinate-system.codeexamplePattern: LOINC code 92822-6
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:coordinate-system.value[x]extensibleLOINC LL5323-2
    http://loinc.org/vs/LL5323-2
    Observation.component:genomic-ref-seq.codeexamplePattern: LOINC code 48013-7
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:genomic-ref-seq.value[x]example
    Observation.component:uncallable-regions.codeexamplePattern: uncallable-regions
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard

    Snapshot View

    NameFlagsCard.TypeDescription & Constraintsdoco
    .. Observation C0..*RegionStudiedRegion Studied
    obs-6: dataAbsentReason SHALL only be present if Observation.value[x] is not present
    obs-7: If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present
    ... id Σ0..1idLogical id of this artifact
    ... meta Σ0..1MetaMetadata about the resource
    ... implicitRules ?!Σ0..1uriA set of rules under which this content was created
    ... language 0..1codeLanguage of the resource content
    Binding: CommonLanguages (preferred): A human language.

    Additional BindingsPurpose
    AllLanguagesMax Binding
    ... text 0..1NarrativeText summary of the resource, for human interpretation
    ... contained 0..*ResourceContained, inline Resources
    ... Slices for extension 0..*ExtensionExtension
    Slice: Unordered, Open by value:url
    ... secondary-finding 0..1CodeableConceptSecondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when [Whole Exome Sequencing (WES)](https://en.wikipedia.org/wiki/Exome_sequencing) or [Whole Genome Sequencing (WGS)](https://en.wikipedia.org/wiki/Whole_genome_sequencing) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement. For more detail, please see: https://ghr.nlm.nih.gov/primer/testing/secondaryfindings
    URL: http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding
    Binding: GeneticObservationSecondaryFindings (extensible): Codes to denote a guideline or policy statement when a genetic test result is being shared as a secondary finding.


    ... body-structure 0..1Reference(BodyStructure)Target anatomic location or structure
    URL: http://hl7.org/fhir/StructureDefinition/bodySite
    ... modifierExtension ?!0..*ExtensionExtensions that cannot be ignored
    ... identifier Σ0..*IdentifierBusiness Identifier for observation
    ... basedOn Σ0..*Reference(CarePlan | DeviceRequest | ImmunizationRecommendation | MedicationRequest | NutritionOrder | ServiceRequest)Fulfills plan, proposal or order
    ... partOf Σ0..*Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Immunization | ImagingStudy)Part of referenced event
    ... status ?!SΣ1..1coderegistered | preliminary | final | amended +
    Binding: ObservationStatus (required): Codes providing the status of an observation.

    ... Slices for category S1..*CodeableConceptClassification of type of observation
    Slice: Unordered, Open by value:coding
    Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.


    .... category:labCategory 1..1CodeableConceptClassification of type of observation
    Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.



    Required Pattern: At least the following
    ..... id0..1stringUnique id for inter-element referencing
    ..... extension0..*ExtensionAdditional content defined by implementations
    ..... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ...... version0..1stringVersion of the system - if relevant
    ...... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    ...... display0..1stringRepresentation defined by the system
    ...... userSelected0..1booleanIf this coding was chosen directly by the user
    ..... text0..1stringPlain text representation of the concept
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    Slice: Unordered, Open by value:url
    ..... coding Σ1..1CodingCode defined by a terminology system

    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... system1..1uriIdentity of the terminology system
    Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
    ...... version0..1stringVersion of the system - if relevant
    ...... code1..1codeSymbol in syntax defined by the system
    Fixed Value: laboratory
    ...... display0..1stringRepresentation defined by the system
    ...... userSelected0..1booleanIf this coding was chosen directly by the user
    ..... text Σ0..1stringPlain text representation of the concept
    ... code SΣ1..1CodeableConcept53041-0
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    .... id0..1stringUnique id for inter-element referencing
    .... extension0..*ExtensionAdditional content defined by implementations
    .... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ..... id0..1stringUnique id for inter-element referencing
    ..... extension0..*ExtensionAdditional content defined by implementations
    ..... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ..... version0..1stringVersion of the system - if relevant
    ..... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 53041-0
    ..... display0..1stringRepresentation defined by the system
    ..... userSelected0..1booleanIf this coding was chosen directly by the user
    .... text0..1stringPlain text representation of the concept
    ... subject SΣ1..1Reference(Cancer Patient Profile)Who and/or what the observation is about
    ... focus Σ0..*Reference(Resource)What the observation is about, when it is not about the subject of record
    ... encounter Σ0..1Reference(Encounter)Healthcare event during which this observation is made
    ... Slices for effective[x] SΣ0..1Clinically relevant time/time-period for observation
    Slice: Unordered, Open by type:$this
    .... effectiveDateTimedateTime
    .... effectivePeriodPeriod
    .... effectiveTimingTiming
    .... effectiveInstantinstant
    .... effective[x]:effectiveDateTime SΣ0..1dateTimeClinically relevant time/time-period for observation
    ... issued Σ0..1instantDate/Time this version was made available
    ... performer Σ0..*Reference(Practitioner | PractitionerRole | Organization | CareTeam | Patient | RelatedPerson)Who is responsible for the observation
    ... dataAbsentReason SC0..1CodeableConceptWhy the result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ... note 0..*CodedAnnotationComments about the Observation that also contain a coded type
    ... bodySite 0..1CodeableConceptObserved body part
    Binding: SNOMEDCTBodyStructures (example): Codes describing anatomical locations. May include laterality.

    ... method 0..1CodeableConceptHow it was done
    Binding: ObservationMethods (example): Methods for simple observations.

    ... specimen 0..1Reference(Specimen)Specimen used for this observation
    ... device 0..1Reference(Device | DeviceMetric)(Measurement) Device
    ... referenceRange C0..*BackboneElementProvides guide for interpretation
    obs-3: Must have at least a low or a high or text
    .... id 0..1stringUnique id for inter-element referencing
    .... extension 0..*ExtensionAdditional content defined by implementations
    .... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    .... low C0..1SimpleQuantityLow Range, if relevant
    .... high C0..1SimpleQuantityHigh Range, if relevant
    .... type 0..1CodeableConceptReference range qualifier
    Binding: ObservationReferenceRangeMeaningCodes (preferred): Code for the meaning of a reference range.

    .... appliesTo 0..*CodeableConceptReference range population
    Binding: ObservationReferenceRangeAppliesToCodes (example): Codes identifying the population the reference range applies to.


    .... age 0..1RangeApplicable age range, if relevant
    .... text 0..1stringText based reference range in an observation
    ... hasMember Σ0..*Reference(Observation | QuestionnaireResponse | MolecularSequence)Related resource that belongs to the Observation group
    ... derivedFrom Σ0..*Reference(DocumentReference | ImagingStudy | Media | QuestionnaireResponse | Observation | MolecularSequence)Related measurements the observation is made from
    ... Slices for component SΣ0..*BackboneElementComponent results
    Slice: Unordered, Open by pattern:code
    .... component:All Slices Content/Rules for all slices
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptType of component observation (code / type)
    Binding: LOINCCodes (example): Codes identifying names of simple observations.

    ..... value[x] Σ0..1Actual component result
    ...... valueQuantityQuantity
    ...... valueCodeableConceptCodeableConcept
    ...... valueStringstring
    ...... valueBooleanboolean
    ...... valueIntegerinteger
    ...... valueRangeRange
    ...... valueRatioRatio
    ...... valueSampledDataSampledData
    ...... valueTimetime
    ...... valueDateTimedateTime
    ...... valuePeriodPeriod
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:conclusion-string Σ0..1BackboneElementClinical Conclusion
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptconclusion-string
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: conclusion-string
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] Σ0..1stringSummary conclusion (interpretation/impression)
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:gene-studied SΣ0..1BackboneElementGene Studied
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept48018-6
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 48018-6
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ1..1CodeableConceptThe HGNC gene symbol is to be used as display text and the HGNC gene ID used as the code. If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used.
    Binding: HUGO Gene Nomenclature Committee Gene Names (HGNC) (extensible)
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:gene-mutations SΣ0..1BackboneElementGene Mutations ID
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept36908-2
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 36908-2
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ1..1CodeableConceptActual component result
    Binding: Human Genome Variation Society (HGVS) Nomenclature (required)
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:region-description SΣ0..1BackboneElementRegion Description
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept81293-3
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 81293-3
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ0..1stringActual component result
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:region-coverage Σ0..1BackboneElementRegion Coverage
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptregion-coverage
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: region-coverage
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] Σ0..1QuantityActual component result
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:ranges-examined SΣ0..*BackboneElementRange(s) of DNA sequence examined
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept51959-5
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 51959-5
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ0..1RangeActual component result
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:coordinate-system SΣ0..1BackboneElementCoordinate System
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept92822-6
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 92822-6
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ1..1CodeableConcept0-based interval counting | 0-based character counting | 1-based character counting
    Binding: LOINC Answer List LL5323-2 (extensible)
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:genomic-ref-seq SΣ0..1BackboneElementGenomic Reference Sequence
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code SΣ1..1CodeableConcept48013-7
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://loinc.org
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: 48013-7
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] SΣ1..1CodeableConceptVersioned genomic reference sequence identifier.
    Binding: (unbound) (example): Multiple bindings acceptable (NCBI or LRG)

    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
    .... component:uncallable-regions Σ0..*BackboneElementUncallable Sub-regions
    ..... id 0..1stringUnique id for inter-element referencing
    ..... extension 0..*ExtensionAdditional content defined by implementations
    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
    ..... code Σ1..1CodeableConceptuncallable-regions
    Binding: LOINCCodes (example): Codes identifying names of simple observations.


    Required Pattern: At least the following
    ...... id0..1stringUnique id for inter-element referencing
    ...... extension0..*ExtensionAdditional content defined by implementations
    ...... coding1..*CodingCode defined by a terminology system
    Fixed Value: (complex)
    ....... id0..1stringUnique id for inter-element referencing
    ....... extension0..*ExtensionAdditional content defined by implementations
    ....... system1..1uriIdentity of the terminology system
    Fixed Value: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
    ....... version0..1stringVersion of the system - if relevant
    ....... code1..1codeSymbol in syntax defined by the system
    Fixed Value: uncallable-regions
    ....... display0..1stringRepresentation defined by the system
    ....... userSelected0..1booleanIf this coding was chosen directly by the user
    ...... text0..1stringPlain text representation of the concept
    ..... value[x] Σ0..1RangeMust be inside the range given by 'ranges examined' in the given reference sequence and coordinate system.
    ..... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
    Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.

    ..... interpretation 0..*CodeableConceptHigh, low, normal, etc.
    Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.


    ..... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result

    doco Documentation for this format

    Terminology Bindings

    PathConformanceValueSet / CodeURI
    Observation.languagepreferredCommonLanguages
    Additional Bindings Purpose
    AllLanguages Max Binding
    http://hl7.org/fhir/ValueSet/languages
    from the FHIR Standard
    Observation.statusrequiredObservationStatus
    http://hl7.org/fhir/ValueSet/observation-status|4.0.1
    from the FHIR Standard
    Observation.categorypreferredObservationCategoryCodes
    http://hl7.org/fhir/ValueSet/observation-category
    from the FHIR Standard
    Observation.category:labCategorypreferredPattern: laboratory
    http://hl7.org/fhir/ValueSet/observation-category
    from the FHIR Standard
    Observation.codeexamplePattern: LOINC code 53041-0
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.bodySiteexampleSNOMEDCTBodyStructures
    http://hl7.org/fhir/ValueSet/body-site
    from the FHIR Standard
    Observation.methodexampleObservationMethods
    http://hl7.org/fhir/ValueSet/observation-methods
    from the FHIR Standard
    Observation.referenceRange.typepreferredObservationReferenceRangeMeaningCodes
    http://hl7.org/fhir/ValueSet/referencerange-meaning
    from the FHIR Standard
    Observation.referenceRange.appliesToexampleObservationReferenceRangeAppliesToCodes
    http://hl7.org/fhir/ValueSet/referencerange-appliesto
    from the FHIR Standard
    Observation.component.codeexampleLOINCCodes (a valid code from LOINC)
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:conclusion-string.codeexamplePattern: conclusion-string
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:conclusion-string.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:conclusion-string.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:gene-studied.codeexamplePattern: LOINC code 48018-6
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-studied.value[x]extensibleHGNCVS
    http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs
    Observation.component:gene-studied.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:gene-studied.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:gene-mutations.codeexamplePattern: LOINC code 36908-2
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:gene-mutations.value[x]requiredHGVSVS
    http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs
    Observation.component:gene-mutations.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:gene-mutations.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:region-description.codeexamplePattern: LOINC code 81293-3
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:region-description.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:region-description.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:region-coverage.codeexamplePattern: region-coverage
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:region-coverage.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:region-coverage.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:ranges-examined.codeexamplePattern: LOINC code 51959-5
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:ranges-examined.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:ranges-examined.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:coordinate-system.codeexamplePattern: LOINC code 92822-6
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:coordinate-system.value[x]extensibleLOINC LL5323-2
    http://loinc.org/vs/LL5323-2
    Observation.component:coordinate-system.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:coordinate-system.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:genomic-ref-seq.codeexamplePattern: LOINC code 48013-7
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:genomic-ref-seq.value[x]example
    Observation.component:genomic-ref-seq.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:genomic-ref-seq.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard
    Observation.component:uncallable-regions.codeexamplePattern: uncallable-regions
    http://hl7.org/fhir/ValueSet/observation-codes
    from the FHIR Standard
    Observation.component:uncallable-regions.dataAbsentReasonextensibleDataAbsentReason
    http://hl7.org/fhir/ValueSet/data-absent-reason
    from the FHIR Standard
    Observation.component:uncallable-regions.interpretationextensibleObservationInterpretationCodes
    http://hl7.org/fhir/ValueSet/observation-interpretation
    from the FHIR Standard

    This structure is derived from RegionStudied

    Summary

    Mandatory: 1 element
    Must-Support: 26 elements

    Structures

    This structure refers to these other structures:

    Slices

    This structure defines the following Slices:

    • The element Observation.effective[x] is sliced based on the value of type:$this

    Maturity: 1

     

    Other representations of profile: CSV, Excel, Schematron