minimal Common Oncology Data Elements (mCODE) Implementation Guide
3.0.0-ballot - 2023May United States of America flag

minimal Common Oncology Data Elements (mCODE) Implementation Guide, published by HL7 International Clinical Interoperability Council. This is not an authorized publication; it is the continuous build for version 3.0.0-ballot). This version is based on the current content of and changes regularly. See the Directory of published versions

Example Observation: genomic-variant-somatic-single-nucleotide

Generated Narrative: Observation

Resource Observation "genomic-variant-somatic-single-nucleotide"

Profile: Genomic Variant Profile

status: final

category: Laboratory (Observation Category Codes#laboratory)

code: Genetic variant assessment (LOINC#69548-6)

subject: Patient/cancer-patient-john-anyperson " ANYPERSON"

effective: 2019-04-01

value: Present (LOINC#LA9633-4)

interpretation: Positive (qualifier value) (SNOMED CT[Intl]#10828004)

method: Sequencing (LOINC#LA26398-0)


code: Gene studied [ID] (LOINC#48018-6)

value: STK11 (HUGO Gene Nomenclature Committee Genes#HGNC:11389)


code: Discrete genetic variant (LOINC#81252-9)

value: NM_000455.5(STK11):c.725G>A (p.Gly242Glu) (ClinVar Variant ID#611264)


code: Genomic DNA change (gHGVS) (LOINC#81290-9)

value: NM_000455.5:c.725G>A (Human Genome Variation Society nomenclature#NM_000455.5:c.725G>A)


code: Genomic source class [Type] (LOINC#48002-0)

value: Somatic (LOINC#LA6684-0)