Potential Drug-Drug Interaction (PDDI) Clinical Decision Support, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/PDDI-CDS/ and changes regularly. See the Directory of published versions

Test data defined as part of the PDDI CDS Implementation Guide

Page standards status: Informative

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To facilitate testing and verification, this guide includes test requests for a number of sample scenarios.

Warfarin + NSAID

All scenarios invoke the CDS service – so prefetch warfarin resources overlap a new NSAID order in each scenario below.

order-select without coordination

• order-select NSAID + Warfarin no coordination

order-sign without coordination

• order-sign NSAID + Warfarin no coordination

order-select with coordination

• order-select NSAID + Warfarin with coordination

order-sign with coordination

• order-sign NSAID + Warfarin with coordination

Multiple updates to the draft orders

• order-select NSAID + Warfarin
• order-select Digoxin + Cyclosporine
• order-sign NSAID + Warfarin
• order-sign Digoxin + Cyclosporine

**Scenario 1: context: topical diclofenac – MedicationRequest; prefetch: warfarin – MedicationRequest **

• Request NSAID + Warfarin scenario 01

Scenario 2: context: systemic NSAID – MedicationRequest; prefetch: warfarin – MedicationRequest, proton pump inhibitor – MedicationRequest,

• Request NSAID + Warfarin scenario 02

Scenario 3: context: systemic NSAID – MedicationRequest; prefetch: wafarin – MedicationDispense, >65 years old – Patient, systemic corticosteroid – MedicationRequest

• Request NSAID + Warfarin scenario 03

Scenario 4: context systemic NSAID – MedicationRequest; prefetch: wafarin – MedicationAdministration, <65 years old – Patient, history of upper gastrointestinal bleed – Condition, NSAID – MedicationRequest

• Request NSAID + Warfarin scenario 04

Scenario 5: context: systemic NSAID – MedicationRequest; prefetch: wafarin – MedicationStatement, <65 years old – Patient, aldosterone antagonist – MedicationRequest

• Request NSAID + Warfarin scenario 05

Digoxin + Cyclosporine

order-select without coordination

• order-select Digoxin + Cyclosporine no coordination

order-sign without coordination

• order-sign Digoxin + Cyclosporine no coordination

order-select with coordination

• order-select Digoxin + Cyclosporine with coordination

order-sign with coordination

• order-sign Digoxin + Cyclosporine with coordination

Scenario 1: context: cyclosporine – MedicationRequest; prefetch: digoxin – MedicationDispense, digoxin level – Observation, furosemide – MedicationDispense

• Request Digoxin + Cyclosporine scenario 01

Scenario 2: context: cyclosporine – MedicationRequest; prefetch: digoxin – MedicationDispense, cyclosporine - MedicationRequest, potassium – Observation,

• Request Digoxin + Cyclosporine scenario 02

Scenario 3: context: digoxin – MedicationRequest; prefetch: cyclosporine – MedicationRequest, renal – Observation

• Request Digoxin + Cyclosporine scenario 03

Scenario 4: context: digoxin – MedicationRequest; prefetch: cyclosporine – MedicationRequest, digoxin – MedicationDispense, digoxin level – Observation

• Request Digoxin + Cyclosporine scenario 04