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Clinical Decision Support Work Group | Maturity Level: N/A | Standards Status: Informative | Compartments: No defined compartments |
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Risk of fatal ICH with alteplase for stroke
@prefix fhir: <http://hl7.org/fhir/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- [a fhir:Evidence ; fhir:nodeRole fhir:treeRoot ; fhir:id [ fhir:v "example-stroke-alteplase-fatalICH"] ; # fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n \n <p>\n "Risk of fatal ICH with alteplase for stroke" is a univariate risk estimate.\n </p>\n \n </div>" ] ; # fhir:extension ( [ fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg"^^xsd:anyURI ] ; fhir:value [ fhir:v "cds" ] ] ) ; # fhir:url [ fhir:v "http://hl7.org/fhir/Evidence/example-stroke-alteplase-fatalICH"^^xsd:anyURI] ; # fhir:identifier ( [ fhir:system [ fhir:v "urn:ietf:rfc:3986"^^xsd:anyURI ] ; fhir:value [ fhir:v "urn:oid:2.16.840.1.113883.4.642.10.1" ] ] ) ; # fhir:name [ fhir:v "RiskOfFatalICHWithAlteplaseForStroke"] ; # fhir:title [ fhir:v "Risk of fatal ICH with alteplase for stroke"] ; # fhir:status [ fhir:v "draft"] ; # fhir:publisher [ fhir:v "HL7 International / Clinical Decision Support"] ; # fhir:contact ( [ fhir:telecom ( [ fhir:system [ fhir:v "url" ] ; fhir:value [ fhir:v "http://www.hl7.org/Special/committees/dss" ] ] ) ] ) ; # fhir:relatedArtifact ( [ fhir:type [ fhir:v "citation" ] ; fhir:label [ fhir:v "Emberson 2014" ] ; fhir:display [ fhir:v "Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials." ] ; fhir:citation [ fhir:v "Emberson J, Lees KR, Lyden P, Blackwell L, Albers G, Bluhmki E, et al;Stroke Thrombolysis Trialists' Collaborative Group. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet 2014 Nov 29;384(9958):1929-35 PMID 25106063" ] ; fhir:document [ fhir:url [ fhir:v "https://doi.org/10.1016/S0140-6736(14)60584-5"^^xsd:anyURI ] ] ] ) ; # fhir:description [ fhir:v "2.7% incidence of fatal intracranial hemorrhage within 7 days with alteplase in patients with acute ischemic stroke"] ; # fhir:variableDefinition ( [ fhir:variableRole [ fhir:v "population" ] ; fhir:observed [ fhir:reference [ fhir:v "Group/Emberson-2014-IPD-MA-Alteplase-Cohort" ] ; fhir:type [ fhir:v "Group"^^xsd:anyURI ] ; fhir:display [ fhir:v "Emberson 2014 IPD-MA Alteplase Cohort" ] ] ; fhir:intended [ fhir:reference [ fhir:v "Group/AcuteIschemicStrokeTreatedWithAlteplase" ] ; fhir:type [ fhir:v "Group"^^xsd:anyURI ] ; fhir:display [ fhir:v "adults with acute ischemic stroke treated with alteplase" ] ] ] [ fhir:variableRole [ fhir:v "outcome" ] ; fhir:observed [ fhir:reference [ fhir:v "EvidenceVariable/example-fatal-ICH-in-7-days" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "fatal ICH" ] ] ; fhir:intended [ fhir:reference [ fhir:v "EvidenceVariable/example-fatal-ICH-in-7-days" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "fatal ICH" ] ] ] ) ; # fhir:synthesisType [ fhir:coding ( [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/synthesis-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "IPD-MA" ] ; fhir:display [ fhir:v "individual patient data meta-analysis" ] ] ) ] ; # fhir:studyDesign ( [ fhir:coding ( [ fhir:system [ fhir:v "http://hl7.org/fhir/study-design"^^xsd:anyURI ] ; fhir:code [ fhir:v "SEVCO:01003" ] ; fhir:display [ fhir:v "randomized assignment" ] ] ) ] ) ; # fhir:statistic ( [ fhir:statisticType [ fhir:coding ( [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/statistic-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "C44256" ] ; fhir:display [ fhir:v "Proportion" ] ] ) ] ; fhir:quantity [ fhir:value [ fhir:v "0.026835741669"^^xsd:decimal ] ] ; fhir:numberOfEvents [ fhir:v "91"^^xsd:nonNegativeInteger ] ; fhir:sampleSize [ fhir:numberOfStudies [ fhir:v "9"^^xsd:nonNegativeInteger ] ; fhir:numberOfParticipants [ fhir:v "3391"^^xsd:nonNegativeInteger ] ] ] )] . # # -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.
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