ACT-NOW Implementation Guide
0.5.0 - ci-build

ACT-NOW Implementation Guide, published by Te aho o te kahu - Cancer Control Agency. This guide is not an authorized publication; it is the continuous build for version 0.5.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/tewhatuora/actnow/ and changes regularly. See the Directory of published versions

## : Dose adjustment reason - JSON Representation

Draft as of 2026-06-15

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    {
      "resourceType" : "ValueSet",
      "id" : "an-dose-adjustment-reason",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ValueSet an-dose-adjustment-reason</b></p><a name=\"an-dose-adjustment-reason\"> </a><a name=\"hcan-dose-adjustment-reason\"> </a><ul><li>Include these codes as defined in <code>http://snomed.info/sct/21000210109</code><span title=\"Version is not explicitly stated. No matching Code System found\"> version Not Stated (use latest from terminology server)</span><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td>271737000</td><td>Anaemia</td></tr><tr><td>262121000210102</td><td>CNS toxicity</td></tr><tr><td>14760008</td><td>Constipation</td></tr><tr><td>414029004</td><td>Immune system disorder</td></tr><tr><td>262111000210107</td><td>Adjusted body weight calculation</td></tr><tr><td>262101000210105</td><td>Dose rounding</td></tr><tr><td>424122007</td><td>ECOG performance status finding</td></tr><tr><td>105593004</td><td>Electrolyte imbalance</td></tr><tr><td>106176003</td><td>Endocrine finding</td></tr><tr><td>248279007</td><td>Frailty</td></tr><tr><td>106028002</td><td>Musculoskeletal finding</td></tr><tr><td>165517008</td><td>Neutropenia</td></tr><tr><td>49808004</td><td>Advanced age</td></tr><tr><td>74964007</td><td>Other</td></tr><tr><td>407566003</td><td>Patient on maximum tolerated dose</td></tr><tr><td>302226006</td><td>Peripheral neuropathy</td></tr><tr><td>302215000</td><td>Thrombocytopenia</td></tr><tr><td>365921005</td><td>Weight change finding</td></tr></table></li></ul></div>"
      },
      "url" : "https://nzhts.digital.health.nz/fhir/ValueSet/canshare-sact-dose-adjustment-reason",
      "version" : "0.5.0",
      "name" : "DoseAdjustmentReason",
      "title" : "Dose adjustment reason",
      "status" : "draft",
      "experimental" : false,
      "date" : "2026-06-15T22:12:46+00:00",
      "publisher" : "Te aho o te kahu - Cancer Control Agency",
      "contact" : [
        {
          "name" : "Te aho o te kahu - Cancer Control Agency",
          "telecom" : [
            {
              "system" : "email",
              "value" : "mailto:david.hay25@gmail.com"
            }
          ]
        }
      ],
      "description" : "Reasons for adjusting the dose of a systemic anti-cancer therapy (SACT) treatment cycle plus other value.",
      "jurisdiction" : [
        {
          "coding" : [
            {
              "system" : "urn:iso:std:iso:3166",
              "code" : "NZ",
              "display" : "New Zealand"
            }
          ]
        }
      ],
      "compose" : {
        "include" : [
          {
            "system" : "http://snomed.info/sct/21000210109",
            "concept" : [
              {
                "code" : "271737000",
                "display" : "Anaemia"
              },
              {
                "code" : "262121000210102",
                "display" : "CNS toxicity"
              },
              {
                "code" : "14760008",
                "display" : "Constipation"
              },
              {
                "code" : "414029004",
                "display" : "Immune system disorder"
              },
              {
                "code" : "262111000210107",
                "display" : "Adjusted body weight calculation"
              },
              {
                "code" : "262101000210105",
                "display" : "Dose rounding"
              },
              {
                "code" : "424122007",
                "display" : "ECOG performance status finding"
              },
              {
                "code" : "105593004",
                "display" : "Electrolyte imbalance"
              },
              {
                "code" : "106176003",
                "display" : "Endocrine finding"
              },
              {
                "code" : "248279007",
                "display" : "Frailty"
              },
              {
                "code" : "106028002",
                "display" : "Musculoskeletal finding"
              },
              {
                "code" : "165517008",
                "display" : "Neutropenia"
              },
              {
                "code" : "49808004",
                "display" : "Advanced age"
              },
              {
                "code" : "74964007",
                "display" : "Other"
              },
              {
                "code" : "407566003",
                "display" : "Patient on maximum tolerated dose"
              },
              {
                "code" : "302226006",
                "display" : "Peripheral neuropathy"
              },
              {
                "code" : "302215000",
                "display" : "Thrombocytopenia"
              },
              {
                "code" : "365921005",
                "display" : "Weight change finding"
              }
            ]
          }
        ]
      }
    }