ACT-NOW Implementation Guide
0.5.0 - ci-build

ACT-NOW Implementation Guide, published by Te aho o te kahu - Cancer Control Agency. This guide is not an authorized publication; it is the continuous build for version 0.5.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/tewhatuora/actnow/ and changes regularly. See the Directory of published versions

## : Dose adjustment reason - XML Representation

Draft as of 2026-06-15

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    <ValueSet xmlns="http://hl7.org/fhir">
      <id value="an-dose-adjustment-reason"/>
      <text>
        <status value="generated"/>
        <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: ValueSet an-dose-adjustment-reason</b></p><a name="an-dose-adjustment-reason"> </a><a name="hcan-dose-adjustment-reason"> </a><ul><li>Include these codes as defined in <code>http://snomed.info/sct/21000210109</code><span title="Version is not explicitly stated. No matching Code System found"> version Not Stated (use latest from terminology server)</span><table class="none"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td></tr><tr><td>271737000</td><td>Anaemia</td></tr><tr><td>262121000210102</td><td>CNS toxicity</td></tr><tr><td>14760008</td><td>Constipation</td></tr><tr><td>414029004</td><td>Immune system disorder</td></tr><tr><td>262111000210107</td><td>Adjusted body weight calculation</td></tr><tr><td>262101000210105</td><td>Dose rounding</td></tr><tr><td>424122007</td><td>ECOG performance status finding</td></tr><tr><td>105593004</td><td>Electrolyte imbalance</td></tr><tr><td>106176003</td><td>Endocrine finding</td></tr><tr><td>248279007</td><td>Frailty</td></tr><tr><td>106028002</td><td>Musculoskeletal finding</td></tr><tr><td>165517008</td><td>Neutropenia</td></tr><tr><td>49808004</td><td>Advanced age</td></tr><tr><td>74964007</td><td>Other</td></tr><tr><td>407566003</td><td>Patient on maximum tolerated dose</td></tr><tr><td>302226006</td><td>Peripheral neuropathy</td></tr><tr><td>302215000</td><td>Thrombocytopenia</td></tr><tr><td>365921005</td><td>Weight change finding</td></tr></table></li></ul></div>
      </text>
      <url
           value="https://nzhts.digital.health.nz/fhir/ValueSet/canshare-sact-dose-adjustment-reason"/>
      <version value="0.5.0"/>
      <name value="DoseAdjustmentReason"/>
      <title value="Dose adjustment reason"/>
      <status value="draft"/>
      <experimental value="false"/>
      <date value="2026-06-15T22:12:46+00:00"/>
      <publisher value="Te aho o te kahu - Cancer Control Agency"/>
      <contact>
        <name value="Te aho o te kahu - Cancer Control Agency"/>
        <telecom>
          <system value="email"/>
          <value value="mailto:david.hay25@gmail.com"/>
        </telecom>
      </contact>
      <description
                   value="Reasons for adjusting the dose of a systemic anti-cancer therapy (SACT) treatment cycle plus other value."/>
      <jurisdiction>
        <coding>
          <system value="urn:iso:std:iso:3166"/>
          <code value="NZ"/>
          <display value="New Zealand"/>
        </coding>
      </jurisdiction>
      <compose>
        <include>
          <system value="http://snomed.info/sct/21000210109"/>
          <concept>
            <code value="271737000"/>
            <display value="Anaemia"/>
          </concept>
          <concept>
            <code value="262121000210102"/>
            <display value="CNS toxicity"/>
          </concept>
          <concept>
            <code value="14760008"/>
            <display value="Constipation"/>
          </concept>
          <concept>
            <code value="414029004"/>
            <display value="Immune system disorder"/>
          </concept>
          <concept>
            <code value="262111000210107"/>
            <display value="Adjusted body weight calculation"/>
          </concept>
          <concept>
            <code value="262101000210105"/>
            <display value="Dose rounding"/>
          </concept>
          <concept>
            <code value="424122007"/>
            <display value="ECOG performance status finding"/>
          </concept>
          <concept>
            <code value="105593004"/>
            <display value="Electrolyte imbalance"/>
          </concept>
          <concept>
            <code value="106176003"/>
            <display value="Endocrine finding"/>
          </concept>
          <concept>
            <code value="248279007"/>
            <display value="Frailty"/>
          </concept>
          <concept>
            <code value="106028002"/>
            <display value="Musculoskeletal finding"/>
          </concept>
          <concept>
            <code value="165517008"/>
            <display value="Neutropenia"/>
          </concept>
          <concept>
            <code value="49808004"/>
            <display value="Advanced age"/>
          </concept>
          <concept>
            <code value="74964007"/>
            <display value="Other"/>
          </concept>
          <concept>
            <code value="407566003"/>
            <display value="Patient on maximum tolerated dose"/>
          </concept>
          <concept>
            <code value="302226006"/>
            <display value="Peripheral neuropathy"/>
          </concept>
          <concept>
            <code value="302215000"/>
            <display value="Thrombocytopenia"/>
          </concept>
          <concept>
            <code value="365921005"/>
            <display value="Weight change finding"/>
          </concept>
        </include>
      </compose>
    </ValueSet>