HL7 FHIR Implementation Guide: Common Terminology Criteria (CTC) Adverse Events Release 1 - DRAFT
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HL7 FHIR Implementation Guide: Common Terminology Criteria (CTC) Adverse Events Release 1 - DRAFT, published by HL7 International Clinical Interoperability Council. This guide is not an authorized publication; it is the continuous build for version 0.0.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/standardhealth/fsh-ae/ and changes regularly. See the Directory of published versions

: ae-bundle-kaitlyn-compass-trial - XML Representation

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<Bundle xmlns="http://hl7.org/fhir">
  <id value="ae-bundle-kaitlyn-compass-trial"/>
  <meta>
    <profile
             value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-patient-bundle"/>
  </meta>
  <type value="collection"/>
  <entry>
    <fullUrl value="http://example.org/patient-example-kaitlyn-b"/>
    <resource>
      <Patient>
        <id value="patient-example-kaitlyn-b"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-patient"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Patient_patient-example-kaitlyn-b"> </a><p><b>Generated Narrative: Patient</b><a name="patient-example-kaitlyn-b"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Patient &quot;patient-example-kaitlyn-b&quot; </p><p style="margin-bottom: 0px">Profile: <a href="http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-patient.html">Cancer Patient</a></p></div><p><b>identifier</b>: Medical Record Number/m123 (use: USUAL)</p><p><b>name</b>: Kaitlyn Bounce </p><p><b>gender</b>: female</p><p><b>birthDate</b>: 1985-02-20</p><p><b>address</b>: 123 Main St Anytown 12345 US </p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Telecom</b></td></tr><tr><td style="display: none">*</td><td>ph: 545-123-4560(HOME), <a href="mailto:kaitlynb@example.com">kaitlynb@example.com</a></td></tr></table><h3>Communications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Language</b></td></tr><tr><td style="display: none">*</td><td>English <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-ietf3066.html">Tags for the Identification of Languages</a>#en-US &quot;English (Region=United States)&quot;)</span></td></tr></table></div>
        </text>
        <identifier>
          <use value="usual"/>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="MR"/>
              <display value="Medical Record Number"/>
            </coding>
          </type>
          <system value="http://hospital.example.org"/>
          <value value="m123"/>
        </identifier>
        <name>
          <family value="Bounce"/>
          <given value="Kaitlyn"/>
        </name>
        <gender value="female"/>
        <birthDate value="1985-02-20"/>
        <address>
          <line value="123 Main St"/>
          <city value="Anytown"/>
          <postalCode value="12345"/>
          <country value="US"/>
        </address>
        <contact>
          <telecom>
            <system value="phone"/>
            <value value="545-123-4560"/>
            <use value="home"/>
          </telecom>
          <telecom>
            <system value="email"/>
            <value value="kaitlynb@example.com"/>
          </telecom>
        </contact>
        <communication>
          <language>
            <coding>
              <system value="urn:ietf:bcp:47"/>
              <code value="en-US"/>
              <display value="English (Region=United States)"/>
            </coding>
            <text value="English"/>
          </language>
        </communication>
      </Patient>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/kaitlyn-primary-cancer-condition-ex1"/>
    <resource>
      <Condition>
        <id value="KaitlynPrimaryCancerConditionEx1"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-primary-cancer-condition"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_KaitlynPrimaryCancerConditionEx1"> </a><p><b>Generated Narrative: Condition</b><a name="KaitlynPrimaryCancerConditionEx1"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition &quot;KaitlynPrimaryCancerConditionEx1&quot; </p><p style="margin-bottom: 0px">Profile: <a href="http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-primary-cancer-condition.html">Primary Cancer Condition</a></p></div><p><b>clinicalStatus</b>: Active <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-condition-clinical.html">Condition Clinical Status Codes</a>#active)</span></p><p><b>verificationStatus</b>: Confirmed <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-condition-ver-status.html">ConditionVerificationStatus</a>#confirmed)</span></p><p><b>category</b>: problem-list-item <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ([not stated]#problem-list-item)</span></p><p><b>code</b>: Malignant neoplasm of female left breast (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#353431000119107)</span></p><p><b>subject</b>: <a href="#Patient_patient-example-kaitlyn-b">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>onset</b>: 2019-05-01</p><p><b>asserter</b>: <a href="Practitioner-PractitionerExample1.html">Practitioner/PractitionerExample1</a> &quot; ANYDOC&quot;</p></div>
        </text>
        <clinicalStatus>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/condition-clinical"/>
            <code value="active"/>
            <display value="Active"/>
          </coding>
        </clinicalStatus>
        <verificationStatus>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/condition-ver-status"/>
            <code value="confirmed"/>
            <display value="Confirmed"/>
          </coding>
        </verificationStatus>
        <category>
          <coding>
            <code value="problem-list-item"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="353431000119107"/>
            <display
                     value="Malignant neoplasm of female left breast (disorder)"/>
          </coding>
        </code>
        <subject>🔗 
          <reference value="Patient/patient-example-kaitlyn-b"/>
        </subject>
        <onsetDateTime value="2019-05-01"/>
        <asserter>🔗 
          <reference value="Practitioner/PractitionerExample1"/>
        </asserter>
      </Condition>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/medication-request-example-kadcyla"/>
    <resource>
      <MedicationRequest>
        <id value="medication-request-example-kadcyla"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-request"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicationRequest_medication-request-example-kadcyla"> </a><p><b>Generated Narrative: MedicationRequest</b><a name="medication-request-example-kadcyla"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicationRequest &quot;medication-request-example-kadcyla&quot; </p><p style="margin-bottom: 0px">Profile: <a href="http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-request.html">Cancer-Related Medication Request</a></p></div><p><b>status</b>: active</p><p><b>intent</b>: order</p><p><b>medication</b>: KADCYLA <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html">RxNorm</a>#1371046)</span></p><p><b>subject</b>: <a href="#Patient_patient-example-kaitlyn-b">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>authoredOn</b>: 2020-03-12</p><p><b>requester</b>: <a href="Practitioner-PractitionerExample1.html">Practitioner/PractitionerExample1</a> &quot; ANYDOC&quot;</p><p><b>reasonReference</b>: <a href="#Condition_KaitlynPrimaryCancerConditionEx1">See above (Condition/KaitlynPrimaryCancerConditionEx1)</a></p><blockquote><p><b>dosageInstruction</b></p><p><b>text</b>: Kadcyla IV at 3.6mg</p><p><b>timing</b>: Starting 2020-04-01, Once</p><p><b>route</b>: Intravenous route (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#47625008)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote><p><b>maxDosePerAdministration</b>: 1</p></blockquote></div>
        </text>
        <status value="active"/>
        <intent value="order"/>
        <medicationCodeableConcept>
          <coding>
            <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
            <code value="1371046"/>
            <display value="KADCYLA"/>
          </coding>
        </medicationCodeableConcept>
        <subject>🔗 
          <reference value="Patient/patient-example-kaitlyn-b"/>
        </subject>
        <authoredOn value="2020-03-12"/>
        <requester>🔗 
          <reference value="Practitioner/PractitionerExample1"/>
        </requester>
        <reasonReference>🔗 
          <reference value="Condition/KaitlynPrimaryCancerConditionEx1"/>
        </reasonReference>
        <dosageInstruction>
          <text value="Kadcyla IV at 3.6mg"/>
          <timing>
            <repeat>
              <boundsPeriod>
                <start value="2020-04-01"/>
              </boundsPeriod>
            </repeat>
          </timing>
          <route>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="47625008"/>
              <display value="Intravenous route (qualifier value)"/>
            </coding>
          </route>
          <doseAndRate>
            <rateQuantity>
              <value value="3.6"/>
              <unit value="mg"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg"/>
            </rateQuantity>
          </doseAndRate>
          <maxDosePerAdministration>
            <value value="1"/>
          </maxDosePerAdministration>
        </dosageInstruction>
      </MedicationRequest>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/medication-request-example-tucatinib"/>
    <resource>
      <MedicationRequest>
        <id value="medication-request-example-tucatinib"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-request"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicationRequest_medication-request-example-tucatinib"> </a><p><b>Generated Narrative: MedicationRequest</b><a name="medication-request-example-tucatinib"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicationRequest &quot;medication-request-example-tucatinib&quot; </p><p style="margin-bottom: 0px">Profile: <a href="http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-request.html">Cancer-Related Medication Request</a></p></div><p><b>status</b>: active</p><p><b>intent</b>: order</p><p><b>medication</b>: tucatinib 150 MG Oral Tablet <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html">RxNorm</a>#2361290)</span></p><p><b>subject</b>: <a href="#Patient_patient-example-kaitlyn-b">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>authoredOn</b>: 2020-03-12</p><p><b>requester</b>: <a href="Practitioner-PractitionerExample1.html">Practitioner/PractitionerExample1</a> &quot; ANYDOC&quot;</p><p><b>reasonReference</b>: <a href="#Condition_KaitlynPrimaryCancerConditionEx1">See above (Condition/KaitlynPrimaryCancerConditionEx1)</a></p><blockquote><p><b>dosageInstruction</b></p><p><b>text</b>: oral twice a day every day</p><p><b>timing</b>: Starting 2020-04-01, Once</p><p><b>route</b>: Oral route (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#26643006)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote><p><b>maxDosePerAdministration</b>: 2</p></blockquote></div>
        </text>
        <status value="active"/>
        <intent value="order"/>
        <medicationCodeableConcept>
          <coding>
            <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
            <code value="2361290"/>
            <display value="tucatinib 150 MG Oral Tablet"/>
          </coding>
        </medicationCodeableConcept>
        <subject>🔗 
          <reference value="Patient/patient-example-kaitlyn-b"/>
        </subject>
        <authoredOn value="2020-03-12"/>
        <requester>🔗 
          <reference value="Practitioner/PractitionerExample1"/>
        </requester>
        <reasonReference>🔗 
          <reference value="Condition/KaitlynPrimaryCancerConditionEx1"/>
        </reasonReference>
        <dosageInstruction>
          <text value="oral twice a day every day"/>
          <timing>
            <repeat>
              <boundsPeriod>
                <start value="2020-04-01"/>
              </boundsPeriod>
            </repeat>
          </timing>
          <route>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="26643006"/>
              <display value="Oral route (qualifier value)"/>
            </coding>
          </route>
          <doseAndRate>
            <rateQuantity>
              <value value="150"/>
              <unit value="MG"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="MG"/>
            </rateQuantity>
          </doseAndRate>
          <maxDosePerAdministration>
            <value value="2"/>
          </maxDosePerAdministration>
        </dosageInstruction>
      </MedicationRequest>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/medication-administration-kadcyla"/>
    <resource>
      <MedicationAdministration>
        <id value="medication-administration-kadcyla"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-administration"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicationAdministration_medication-administration-kadcyla"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name="medication-administration-kadcyla"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicationAdministration &quot;medication-administration-kadcyla&quot; </p><p style="margin-bottom: 0px">Profile: <a href="http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-administration.html">Cancer-Related Medication Administration</a></p></div><p><b>status</b>: completed</p><p><b>medication</b>: KADCYLA <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html">RxNorm</a>#1371046)</span></p><p><b>subject</b>: <a href="#Patient_patient-example-kaitlyn-b">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>effective</b>: 2020-04-01</p><h3>Performers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Actor</b></td></tr><tr><td style="display: none">*</td><td><a href="Practitioner-practitioner-oncology-nurse-jane.html">Practitioner/practitioner-oncology-nurse-jane</a> &quot; NURSE&quot;</td></tr></table><p><b>reasonReference</b>: <a href="#Condition_KaitlynPrimaryCancerConditionEx1">See above (Condition/KaitlynPrimaryCancerConditionEx1)</a></p><p><b>request</b>: <a href="#MedicationRequest_medication-request-example-kadcyla">See above (MedicationRequest/medication-request-example-kadcyla)</a></p><p><b>note</b>: 3.6mg administered by continuous infusion. Patient tolerated infusion without side effects. (By Practitioner/practitioner-oncology-nurse-jane @2020-04-01)</p><h3>Dosages</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Route</b></td><td><b>Dose</b></td></tr><tr><td style="display: none">*</td><td>Intravenous route (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#47625008)</span></td><td>3.6 mg<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg = 'mg')</span></td></tr></table></div>
        </text>
        <status value="completed"/>
        <medicationCodeableConcept>
          <coding>
            <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
            <code value="1371046"/>
            <display value="KADCYLA"/>
          </coding>
        </medicationCodeableConcept>
        <subject>🔗 
          <reference value="Patient/patient-example-kaitlyn-b"/>
        </subject>
        <effectiveDateTime value="2020-04-01"/>
        <performer>
          <actor>🔗 
            <reference value="Practitioner/practitioner-oncology-nurse-jane"/>
          </actor>
        </performer>
        <reasonReference>🔗 
          <reference value="Condition/KaitlynPrimaryCancerConditionEx1"/>
        </reasonReference>
        <request>🔗 
          <reference
                     value="MedicationRequest/medication-request-example-kadcyla"/>
        </request>
        <note>
          <authorReference>🔗 
            <reference value="Practitioner/practitioner-oncology-nurse-jane"/>
          </authorReference>
          <time value="2020-04-01"/>
          <text
                value="3.6mg administered by continuous infusion. Patient tolerated infusion without side effects."/>
        </note>
        <dosage>
          <route>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="47625008"/>
              <display value="Intravenous route (qualifier value)"/>
            </coding>
          </route>
          <dose>
            <value value="3.6"/>
            <unit value="mg"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="mg"/>
          </dose>
        </dosage>
      </MedicationAdministration>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/medication-administration-tucatinib"/>
    <resource>
      <MedicationAdministration>
        <id value="medication-administration-tucatinib"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-administration"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicationAdministration_medication-administration-tucatinib"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name="medication-administration-tucatinib"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicationAdministration &quot;medication-administration-tucatinib&quot; </p><p style="margin-bottom: 0px">Profile: <a href="http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-administration.html">Cancer-Related Medication Administration</a></p></div><p><b>status</b>: completed</p><p><b>medication</b>: tucatinib 150 MG Oral Tablet <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html">RxNorm</a>#2361290)</span></p><p><b>subject</b>: <a href="#Patient_patient-example-kaitlyn-b">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>effective</b>: 2020-04-01</p><h3>Performers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Actor</b></td></tr><tr><td style="display: none">*</td><td><a href="Practitioner-practitioner-oncology-nurse-jane.html">Practitioner/practitioner-oncology-nurse-jane</a> &quot; NURSE&quot;</td></tr></table><p><b>reasonReference</b>: <a href="#Condition_KaitlynPrimaryCancerConditionEx1">See above (Condition/KaitlynPrimaryCancerConditionEx1)</a></p><p><b>request</b>: <a href="#MedicationRequest_medication-request-example-tucatinib">See above (MedicationRequest/medication-request-example-tucatinib)</a></p><p><b>note</b>: Patient took 2 tablets (By Practitioner/practitioner-oncology-nurse-jane @2020-04-01)</p><h3>Dosages</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Route</b></td><td><b>Dose</b></td></tr><tr><td style="display: none">*</td><td>Oral route (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#26643006)</span></td><td>300 MG<span style="background: LightGoldenRodYellow"> (Details: UCUM code MG = 'MG')</span></td></tr></table></div>
        </text>
        <status value="completed"/>
        <medicationCodeableConcept>
          <coding>
            <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
            <code value="2361290"/>
            <display value="tucatinib 150 MG Oral Tablet"/>
          </coding>
        </medicationCodeableConcept>
        <subject>🔗 
          <reference value="Patient/patient-example-kaitlyn-b"/>
        </subject>
        <effectiveDateTime value="2020-04-01"/>
        <performer>
          <actor>🔗 
            <reference value="Practitioner/practitioner-oncology-nurse-jane"/>
          </actor>
        </performer>
        <reasonReference>🔗 
          <reference value="Condition/KaitlynPrimaryCancerConditionEx1"/>
        </reasonReference>
        <request>🔗 
          <reference
                     value="MedicationRequest/medication-request-example-tucatinib"/>
        </request>
        <note>
          <authorReference>🔗 
            <reference value="Practitioner/practitioner-oncology-nurse-jane"/>
          </authorReference>
          <time value="2020-04-01"/>
          <text value="Patient took 2 tablets"/>
        </note>
        <dosage>
          <route>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="26643006"/>
              <display value="Oral route (qualifier value)"/>
            </coding>
          </route>
          <dose>
            <value value="300"/>
            <unit value="MG"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="MG"/>
          </dose>
        </dosage>
      </MedicationAdministration>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/ctc-adverse-event-compass-ex1"/>
    <resource>
      <AdverseEvent>
        <id value="ctc-adverse-event-compass-ex1"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/ctcae/StructureDefinition/ctc-adverse-event"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="AdverseEvent_ctc-adverse-event-compass-ex1"> </a><p><b>Generated Narrative: AdverseEvent</b><a name="ctc-adverse-event-compass-ex1"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource AdverseEvent &quot;ctc-adverse-event-compass-ex1&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ctc-adverse-event.html">CTC Adverse Event</a></p></div><p><b>CTC Adverse Event Grade</b>: Mild Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ctcae-grade-code-system.html">CTCAE Grade Code System</a>#1)</span></p><blockquote><p><b>Adverse Event Participant</b></p><blockquote><p><b>url</b></p><code>function</code></blockquote><p><b>value</b>: authenticator <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-ParticipationType.html">ParticipationType</a>#AUTHEN)</span></p><blockquote><p><b>url</b></p><code>actor</code></blockquote><p><b>value</b>: <a href="Practitioner-us-core-practitioner-owen-oncologist.html">Practitioner/us-core-practitioner-owen-oncologist</a> &quot; ONCOLOGIST&quot;</p></blockquote><p><b>Adverse Event Expectation</b>: Expected Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C41333)</span></p><p><b>actuality</b>: actual</p><p><b>event</b>: Alanine aminotransferase (ALT) increased at 50 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (MedDRA Am Engl[20.3]#10001551 &quot;Alanine aminotransferase increased&quot;)</span></p><p><b>subject</b>: <a href="#Patient_patient-example-kaitlyn-b">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>date</b>: 2020-04-22</p><p><b>seriousness</b>: Non-serious Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C41336)</span></p><p><b>outcome</b>: Ongoing <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R4/codesystem-adverse-event-outcome.html">AdverseEventOutcome</a>#ongoing)</span></p><p><b>recorder</b>: <a href="Practitioner-us-core-practitioner-nancy-oncology-nurse.html">Practitioner/us-core-practitioner-nancy-oncology-nurse</a> &quot; NURSE&quot;</p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href="#MedicationAdministration_medication-administration-kadcyla">See above (MedicationAdministration/medication-administration-kadcyla)</a></p><h3>Causalities</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Assessment</b></td></tr><tr><td style="display: none">*</td><td>Adverse Event Probably Related to Intervention <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href="#MedicationAdministration_medication-administration-tucatinib">See above (MedicationAdministration/medication-administration-tucatinib)</a></p><h3>Causalities</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Assessment</b></td></tr><tr><td style="display: none">*</td><td>Adverse Event Probably Related to Intervention <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><p><b>study</b>: <a href="#ResearchStudy_clinical-trial-example-compass">See above (ResearchStudy/clinical-trial-example-compass)</a></p></div>
        </text>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/ctcae-grade">
          <valueCodeableConcept>
            <coding>
              <system
                      value="http://hl7.org/fhir/us/ctcae/CodeSystem/ctcae-grade-code-system"/>
              <code value="1"/>
            </coding>
          </valueCodeableConcept>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-participant">
          <extension url="function">
            <valueCodeableConcept>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/v3-ParticipationType"/>
                <code value="AUTHEN"/>
              </coding>
            </valueCodeableConcept>
          </extension>
          <extension url="actor">
            <valueReference>🔗 
              <reference
                         value="Practitioner/us-core-practitioner-owen-oncologist"/>
            </valueReference>
          </extension>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-expectation">
          <valueCodeableConcept>
            <coding>
              <system
                      value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
              <code value="C41333"/>
              <display value="Expected Adverse Event"/>
            </coding>
          </valueCodeableConcept>
        </extension>
        <actuality value="actual"/>
        <event>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/MDRAE"/>
            <version value="20.3"/>
            <code value="10001551"/>
            <display value="Alanine aminotransferase increased"/>
          </coding>
          <text value="Alanine aminotransferase (ALT) increased at 50"/>
        </event>
        <subject>🔗 
          <reference value="Patient/patient-example-kaitlyn-b"/>
        </subject>
        <date value="2020-04-22"/>
        <seriousness>
          <coding>
            <system
                    value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
            <code value="C41336"/>
            <display value="Non-serious Adverse Event"/>
          </coding>
        </seriousness>
        <outcome>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/adverse-event-outcome"/>
            <code value="ongoing"/>
          </coding>
        </outcome>
        <recorder>🔗 
          <reference
                     value="Practitioner/us-core-practitioner-nancy-oncology-nurse"/>
        </recorder>
        <suspectEntity>
          <instance>🔗 
            <reference
                       value="MedicationAdministration/medication-administration-kadcyla"/>
          </instance>
          <causality>
            <assessment>
              <coding>
                <system
                        value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                <code value="C53259"/>
              </coding>
              <text value="Adverse Event Probably Related to Intervention"/>
            </assessment>
          </causality>
        </suspectEntity>
        <suspectEntity>
          <instance>🔗 
            <reference
                       value="MedicationAdministration/medication-administration-tucatinib"/>
          </instance>
          <causality>
            <assessment>
              <coding>
                <system
                        value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                <code value="C53259"/>
              </coding>
              <text value="Adverse Event Probably Related to Intervention"/>
            </assessment>
          </causality>
        </suspectEntity>
        <study>🔗 
          <reference value="ResearchStudy/clinical-trial-example-compass"/>
        </study>
      </AdverseEvent>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/ctc-adverse-event-compass-ex1a"/>
    <resource>
      <AdverseEvent>
        <id value="ctc-adverse-event-compass-ex1a"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/ctcae/StructureDefinition/ctc-adverse-event"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="AdverseEvent_ctc-adverse-event-compass-ex1a"> </a><p><b>Generated Narrative: AdverseEvent</b><a name="ctc-adverse-event-compass-ex1a"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource AdverseEvent &quot;ctc-adverse-event-compass-ex1a&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ctc-adverse-event.html">CTC Adverse Event</a></p></div><p><b>CTC Adverse Event Grade</b>: Severe Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ctcae-grade-code-system.html">CTCAE Grade Code System</a>#3)</span></p><blockquote><p><b>Adverse Event Participant</b></p><blockquote><p><b>url</b></p><code>function</code></blockquote><p><b>value</b>: authenticator <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-ParticipationType.html">ParticipationType</a>#AUTHEN)</span></p><blockquote><p><b>url</b></p><code>actor</code></blockquote><p><b>value</b>: <a href="Practitioner-us-core-practitioner-owen-oncologist.html">Practitioner/us-core-practitioner-owen-oncologist</a> &quot; ONCOLOGIST&quot;</p></blockquote><p><b>Adverse Event Expectation</b>: Expected Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C41333)</span></p><p><b>actuality</b>: actual</p><p><b>event</b>: Alanine aminotransferase (ALT) increased to 200 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (MedDRA Am Engl[20.3]#10001551 &quot;Alanine aminotransferase increased&quot;)</span></p><p><b>subject</b>: <a href="#Patient_patient-example-kaitlyn-b">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>date</b>: 2020-05-13</p><p><b>seriousness</b>: Non-serious Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C41336)</span></p><p><b>outcome</b>: Ongoing <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R4/codesystem-adverse-event-outcome.html">AdverseEventOutcome</a>#ongoing)</span></p><p><b>recorder</b>: <a href="Practitioner-us-core-practitioner-nancy-oncology-nurse.html">Practitioner/us-core-practitioner-nancy-oncology-nurse</a> &quot; NURSE&quot;</p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href="#MedicationAdministration_medication-administration-kadcyla">See above (MedicationAdministration/medication-administration-kadcyla)</a></p><h3>Causalities</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Assessment</b></td></tr><tr><td style="display: none">*</td><td>Adverse Event Probably Related to Intervention <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href="#MedicationAdministration_medication-administration-tucatinib">See above (MedicationAdministration/medication-administration-tucatinib)</a></p><h3>Causalities</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Assessment</b></td></tr><tr><td style="display: none">*</td><td>Adverse Event Probably Related to Intervention <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><p><b>study</b>: <a href="#ResearchStudy_clinical-trial-example-compass">See above (ResearchStudy/clinical-trial-example-compass)</a></p></div>
        </text>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/ctcae-grade">
          <valueCodeableConcept>
            <coding>
              <system
                      value="http://hl7.org/fhir/us/ctcae/CodeSystem/ctcae-grade-code-system"/>
              <code value="3"/>
            </coding>
          </valueCodeableConcept>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-participant">
          <extension url="function">
            <valueCodeableConcept>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/v3-ParticipationType"/>
                <code value="AUTHEN"/>
              </coding>
            </valueCodeableConcept>
          </extension>
          <extension url="actor">
            <valueReference>🔗 
              <reference
                         value="Practitioner/us-core-practitioner-owen-oncologist"/>
            </valueReference>
          </extension>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-expectation">
          <valueCodeableConcept>
            <coding>
              <system
                      value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
              <code value="C41333"/>
              <display value="Expected Adverse Event"/>
            </coding>
          </valueCodeableConcept>
        </extension>
        <actuality value="actual"/>
        <event>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/MDRAE"/>
            <version value="20.3"/>
            <code value="10001551"/>
            <display value="Alanine aminotransferase increased"/>
          </coding>
          <text value="Alanine aminotransferase (ALT) increased to 200"/>
        </event>
        <subject>🔗 
          <reference value="Patient/patient-example-kaitlyn-b"/>
        </subject>
        <date value="2020-05-13"/>
        <seriousness>
          <coding>
            <system
                    value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
            <code value="C41336"/>
            <display value="Non-serious Adverse Event"/>
          </coding>
        </seriousness>
        <outcome>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/adverse-event-outcome"/>
            <code value="ongoing"/>
          </coding>
        </outcome>
        <recorder>🔗 
          <reference
                     value="Practitioner/us-core-practitioner-nancy-oncology-nurse"/>
        </recorder>
        <suspectEntity>
          <instance>🔗 
            <reference
                       value="MedicationAdministration/medication-administration-kadcyla"/>
          </instance>
          <causality>
            <assessment>
              <coding>
                <system
                        value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                <code value="C53259"/>
              </coding>
              <text value="Adverse Event Probably Related to Intervention"/>
            </assessment>
          </causality>
        </suspectEntity>
        <suspectEntity>
          <instance>🔗 
            <reference
                       value="MedicationAdministration/medication-administration-tucatinib"/>
          </instance>
          <causality>
            <assessment>
              <coding>
                <system
                        value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                <code value="C53259"/>
              </coding>
              <text value="Adverse Event Probably Related to Intervention"/>
            </assessment>
          </causality>
        </suspectEntity>
        <study>🔗 
          <reference value="ResearchStudy/clinical-trial-example-compass"/>
        </study>
      </AdverseEvent>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/ctc-adverse-event-compass-ex1b"/>
    <resource>
      <AdverseEvent>
        <id value="ctc-adverse-event-compass-ex1b"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/ctcae/StructureDefinition/ctc-adverse-event"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="AdverseEvent_ctc-adverse-event-compass-ex1b"> </a><p><b>Generated Narrative: AdverseEvent</b><a name="ctc-adverse-event-compass-ex1b"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource AdverseEvent &quot;ctc-adverse-event-compass-ex1b&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ctc-adverse-event.html">CTC Adverse Event</a></p></div><p><b>CTC Adverse Event Grade</b>: Mild Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ctcae-grade-code-system.html">CTCAE Grade Code System</a>#1)</span></p><blockquote><p><b>Adverse Event Participant</b></p><blockquote><p><b>url</b></p><code>function</code></blockquote><p><b>value</b>: authenticator <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-ParticipationType.html">ParticipationType</a>#AUTHEN)</span></p><blockquote><p><b>url</b></p><code>actor</code></blockquote><p><b>value</b>: <a href="Practitioner-us-core-practitioner-owen-oncologist.html">Practitioner/us-core-practitioner-owen-oncologist</a> &quot; ONCOLOGIST&quot;</p></blockquote><p><b>Adverse Event Expectation</b>: Expected Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C41333)</span></p><p><b>Adverse Event Resolved Date</b>: 2020-06-10</p><p><b>actuality</b>: actual</p><p><b>event</b>: Alanine aminotransferase (ALT) decreased to 60 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (MedDRA Am Engl[20.3]#10001551 &quot;Alanine aminotransferase increased&quot;)</span></p><p><b>subject</b>: <a href="#Patient_patient-example-kaitlyn-b">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>date</b>: 2020-05-20</p><p><b>seriousness</b>: Non-serious Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C41336)</span></p><p><b>outcome</b>: Resolved <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R4/codesystem-adverse-event-outcome.html">AdverseEventOutcome</a>#resolved)</span></p><p><b>recorder</b>: <a href="Practitioner-us-core-practitioner-nancy-oncology-nurse.html">Practitioner/us-core-practitioner-nancy-oncology-nurse</a> &quot; NURSE&quot;</p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href="#MedicationAdministration_medication-administration-kadcyla">See above (MedicationAdministration/medication-administration-kadcyla)</a></p><h3>Causalities</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Assessment</b></td></tr><tr><td style="display: none">*</td><td>Adverse Event Probably Related to Intervention <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href="#MedicationAdministration_medication-administration-tucatinib">See above (MedicationAdministration/medication-administration-tucatinib)</a></p><h3>Causalities</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Assessment</b></td></tr><tr><td style="display: none">*</td><td>Adverse Event Probably Related to Intervention <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><p><b>study</b>: <a href="#ResearchStudy_clinical-trial-example-compass">See above (ResearchStudy/clinical-trial-example-compass)</a></p></div>
        </text>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/ctcae-grade">
          <valueCodeableConcept>
            <coding>
              <system
                      value="http://hl7.org/fhir/us/ctcae/CodeSystem/ctcae-grade-code-system"/>
              <code value="1"/>
            </coding>
          </valueCodeableConcept>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-participant">
          <extension url="function">
            <valueCodeableConcept>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/v3-ParticipationType"/>
                <code value="AUTHEN"/>
              </coding>
            </valueCodeableConcept>
          </extension>
          <extension url="actor">
            <valueReference>🔗 
              <reference
                         value="Practitioner/us-core-practitioner-owen-oncologist"/>
            </valueReference>
          </extension>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-expectation">
          <valueCodeableConcept>
            <coding>
              <system
                      value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
              <code value="C41333"/>
              <display value="Expected Adverse Event"/>
            </coding>
          </valueCodeableConcept>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-resolved-date">
          <valueDateTime value="2020-06-10"/>
        </extension>
        <actuality value="actual"/>
        <event>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/MDRAE"/>
            <version value="20.3"/>
            <code value="10001551"/>
            <display value="Alanine aminotransferase increased"/>
          </coding>
          <text value="Alanine aminotransferase (ALT) decreased to 60"/>
        </event>
        <subject>🔗 
          <reference value="Patient/patient-example-kaitlyn-b"/>
        </subject>
        <date value="2020-05-20"/>
        <seriousness>
          <coding>
            <system
                    value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
            <code value="C41336"/>
            <display value="Non-serious Adverse Event"/>
          </coding>
        </seriousness>
        <outcome>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/adverse-event-outcome"/>
            <code value="resolved"/>
          </coding>
        </outcome>
        <recorder>🔗 
          <reference
                     value="Practitioner/us-core-practitioner-nancy-oncology-nurse"/>
        </recorder>
        <suspectEntity>
          <instance>🔗 
            <reference
                       value="MedicationAdministration/medication-administration-kadcyla"/>
          </instance>
          <causality>
            <assessment>
              <coding>
                <system
                        value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                <code value="C53259"/>
              </coding>
              <text value="Adverse Event Probably Related to Intervention"/>
            </assessment>
          </causality>
        </suspectEntity>
        <suspectEntity>
          <instance>🔗 
            <reference
                       value="MedicationAdministration/medication-administration-tucatinib"/>
          </instance>
          <causality>
            <assessment>
              <coding>
                <system
                        value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                <code value="C53259"/>
              </coding>
              <text value="Adverse Event Probably Related to Intervention"/>
            </assessment>
          </causality>
        </suspectEntity>
        <study>🔗 
          <reference value="ResearchStudy/clinical-trial-example-compass"/>
        </study>
      </AdverseEvent>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/ctc-adverse-event-compass-ex2"/>
    <resource>
      <AdverseEvent>
        <id value="ctc-adverse-event-compass-ex2"/>
        <meta>
          <profile
                   value="http://hl7.org/fhir/us/ctcae/StructureDefinition/ctc-adverse-event"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="AdverseEvent_ctc-adverse-event-compass-ex2"> </a><p><b>Generated Narrative: AdverseEvent</b><a name="ctc-adverse-event-compass-ex2"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource AdverseEvent &quot;ctc-adverse-event-compass-ex2&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ctc-adverse-event.html">CTC Adverse Event</a></p></div><p><b>CTC Adverse Event Grade</b>: Mild Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ctcae-grade-code-system.html">CTCAE Grade Code System</a>#1)</span></p><blockquote><p><b>Adverse Event Participant</b></p><blockquote><p><b>url</b></p><code>function</code></blockquote><p><b>value</b>: authenticator <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-ParticipationType.html">ParticipationType</a>#AUTHEN)</span></p><blockquote><p><b>url</b></p><code>actor</code></blockquote><p><b>value</b>: <a href="Practitioner-us-core-practitioner-owen-oncologist.html">Practitioner/us-core-practitioner-owen-oncologist</a> &quot; ONCOLOGIST&quot;</p></blockquote><p><b>Adverse Event Expectation</b>: Expected Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C41333)</span></p><p><b>Adverse Event Resolved Date</b>: 2021-01-21</p><p><b>actuality</b>: actual</p><p><b>event</b>: Nausea <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (MedDRA Am Engl[20.3]#10028813)</span></p><p><b>subject</b>: <a href="#Patient_patient-example-kaitlyn-b">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>date</b>: 2020-05-25</p><p><b>seriousness</b>: Non-serious Adverse Event <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C41336)</span></p><p><b>outcome</b>: Ongoing <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R4/codesystem-adverse-event-outcome.html">AdverseEventOutcome</a>#ongoing)</span></p><p><b>recorder</b>: <a href="Practitioner-us-core-practitioner-nancy-oncology-nurse.html">Practitioner/us-core-practitioner-nancy-oncology-nurse</a> &quot; NURSE&quot;</p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href="#MedicationAdministration_medication-administration-kadcyla">See above (MedicationAdministration/medication-administration-kadcyla)</a></p><h3>Causalities</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Assessment</b></td></tr><tr><td style="display: none">*</td><td>Adverse Event Possibly Related to Intervention <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C53258)</span></td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href="#MedicationAdministration_medication-administration-tucatinib">See above (MedicationAdministration/medication-administration-tucatinib)</a></p><h3>Causalities</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Assessment</b></td></tr><tr><td style="display: none">*</td><td>Adverse Event Probably Related to Intervention <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><p><b>study</b>: <a href="#ResearchStudy_clinical-trial-example-compass">See above (ResearchStudy/clinical-trial-example-compass)</a></p></div>
        </text>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/ctcae-grade">
          <valueCodeableConcept>
            <coding>
              <system
                      value="http://hl7.org/fhir/us/ctcae/CodeSystem/ctcae-grade-code-system"/>
              <code value="1"/>
            </coding>
          </valueCodeableConcept>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-participant">
          <extension url="function">
            <valueCodeableConcept>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/v3-ParticipationType"/>
                <code value="AUTHEN"/>
              </coding>
            </valueCodeableConcept>
          </extension>
          <extension url="actor">
            <valueReference>🔗 
              <reference
                         value="Practitioner/us-core-practitioner-owen-oncologist"/>
            </valueReference>
          </extension>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-expectation">
          <valueCodeableConcept>
            <coding>
              <system
                      value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
              <code value="C41333"/>
              <display value="Expected Adverse Event"/>
            </coding>
          </valueCodeableConcept>
        </extension>
        <extension
                   url="http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-resolved-date">
          <valueDateTime value="2021-01-21"/>
        </extension>
        <actuality value="actual"/>
        <event>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/MDRAE"/>
            <version value="20.3"/>
            <code value="10028813"/>
            <display value="Nausea"/>
          </coding>
          <text value="Nausea"/>
        </event>
        <subject>🔗 
          <reference value="Patient/patient-example-kaitlyn-b"/>
        </subject>
        <date value="2020-05-25"/>
        <seriousness>
          <coding>
            <system
                    value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
            <code value="C41336"/>
            <display value="Non-serious Adverse Event"/>
          </coding>
        </seriousness>
        <outcome>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/adverse-event-outcome"/>
            <code value="ongoing"/>
          </coding>
        </outcome>
        <recorder>🔗 
          <reference
                     value="Practitioner/us-core-practitioner-nancy-oncology-nurse"/>
        </recorder>
        <suspectEntity>
          <instance>🔗 
            <reference
                       value="MedicationAdministration/medication-administration-kadcyla"/>
          </instance>
          <causality>
            <assessment>
              <coding>
                <system
                        value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                <code value="C53258"/>
              </coding>
              <text value="Adverse Event Possibly Related to Intervention"/>
            </assessment>
          </causality>
        </suspectEntity>
        <suspectEntity>
          <instance>🔗 
            <reference
                       value="MedicationAdministration/medication-administration-tucatinib"/>
          </instance>
          <causality>
            <assessment>
              <coding>
                <system
                        value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                <code value="C53259"/>
              </coding>
              <text value="Adverse Event Probably Related to Intervention"/>
            </assessment>
          </causality>
        </suspectEntity>
        <study>🔗 
          <reference value="ResearchStudy/clinical-trial-example-compass"/>
        </study>
      </AdverseEvent>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://example.org/clinical-trial-example-compass"/>
    <resource>
      <ResearchStudy>
        <id value="clinical-trial-example-compass"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="ResearchStudy_clinical-trial-example-compass"> </a><p><b>Generated Narrative: ResearchStudy</b><a name="clinical-trial-example-compass"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ResearchStudy &quot;clinical-trial-example-compass&quot; </p></div><p><b>title</b>: Alliance COMPASS Trial A011801</p><p><b>status</b>: active</p></div>
        </text>
        <title value="Alliance COMPASS Trial A011801"/>
        <status value="active"/>
      </ResearchStudy>
    </resource>
  </entry>
</Bundle>