HL7 FHIR Implementation Guide: Common Terminology Criteria (CTC) Adverse Events Release 1 - DRAFT
0.0.1 - DRAFT
HL7 FHIR Implementation Guide: Common Terminology Criteria (CTC) Adverse Events Release 1 - DRAFT, published by HL7 International Clinical Interoperability Council. This guide is not an authorized publication; it is the continuous build for version 0.0.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/standardhealth/fsh-ae/ and changes regularly. See the Directory of published versions
{
"resourceType" : "Bundle",
"id" : "ae-bundle-kaitlyn-compass-trial",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-patient-bundle"
]
},
"type" : "collection",
"entry" : [
{
"fullUrl" : "http://example.org/patient-example-kaitlyn-b",
"resource" : {
"resourceType" : "Patient",
"id" : "patient-example-kaitlyn-b",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-patient"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Patient_patient-example-kaitlyn-b\"> </a><p><b>Generated Narrative: Patient</b><a name=\"patient-example-kaitlyn-b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Patient "patient-example-kaitlyn-b" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-patient.html\">Cancer Patient</a></p></div><p><b>identifier</b>: Medical Record Number/m123\u00a0(use:\u00a0USUAL)</p><p><b>name</b>: Kaitlyn Bounce </p><p><b>gender</b>: female</p><p><b>birthDate</b>: 1985-02-20</p><p><b>address</b>: 123 Main St Anytown 12345 US </p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Telecom</b></td></tr><tr><td style=\"display: none\">*</td><td>ph: 545-123-4560(HOME), <a href=\"mailto:kaitlynb@example.com\">kaitlynb@example.com</a></td></tr></table><h3>Communications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Language</b></td></tr><tr><td style=\"display: none\">*</td><td>English <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ietf3066.html\">Tags for the Identification of Languages</a>#en-US "English (Region=United States)")</span></td></tr></table></div>"
},
"identifier" : [
{
"use" : "usual",
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
"code" : "MR",
"display" : "Medical Record Number"
}
]
},
"system" : "http://hospital.example.org",
"value" : "m123"
}
],
"name" : [
{
"family" : "Bounce",
"given" : [
"Kaitlyn"
]
}
],
"gender" : "female",
"birthDate" : "1985-02-20",
"address" : [
{
"line" : [
"123 Main St"
],
"city" : "Anytown",
"postalCode" : "12345",
"country" : "US"
}
],
"contact" : [
{
"telecom" : [
{
"system" : "phone",
"value" : "545-123-4560",
"use" : "home"
},
{
"system" : "email",
"value" : "kaitlynb@example.com"
}
]
}
],
"communication" : [
{
"language" : {
"coding" : [
{
"system" : "urn:ietf:bcp:47",
"code" : "en-US",
"display" : "English (Region=United States)"
}
],
"text" : "English"
}
}
]
}
},
{
"fullUrl" : "http://example.org/kaitlyn-primary-cancer-condition-ex1",
"resource" : {
"resourceType" : "Condition",
"id" : "KaitlynPrimaryCancerConditionEx1",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-primary-cancer-condition"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_KaitlynPrimaryCancerConditionEx1\"> </a><p><b>Generated Narrative: Condition</b><a name=\"KaitlynPrimaryCancerConditionEx1\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Condition "KaitlynPrimaryCancerConditionEx1" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-primary-cancer-condition.html\">Primary Cancer Condition</a></p></div><p><b>clinicalStatus</b>: Active <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-condition-clinical.html\">Condition Clinical Status Codes</a>#active)</span></p><p><b>verificationStatus</b>: Confirmed <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-condition-ver-status.html\">ConditionVerificationStatus</a>#confirmed)</span></p><p><b>category</b>: problem-list-item <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ([not stated]#problem-list-item)</span></p><p><b>code</b>: Malignant neoplasm of female left breast (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#353431000119107)</span></p><p><b>subject</b>: <a href=\"#Patient_patient-example-kaitlyn-b\">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>onset</b>: 2019-05-01</p><p><b>asserter</b>: <a href=\"Practitioner-PractitionerExample1.html\">Practitioner/PractitionerExample1</a> " ANYDOC"</p></div>"
},
"clinicalStatus" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/condition-clinical",
"code" : "active",
"display" : "Active"
}
]
},
"verificationStatus" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/condition-ver-status",
"code" : "confirmed",
"display" : "Confirmed"
}
]
},
"category" : [
{
"coding" : [
{
"code" : "problem-list-item"
}
]
}
],
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "353431000119107",
"display" : "Malignant neoplasm of female left breast (disorder)"
}
]
},
"subject" : {
🔗 "reference" : "Patient/patient-example-kaitlyn-b"
},
"onsetDateTime" : "2019-05-01",
"asserter" : {
🔗 "reference" : "Practitioner/PractitionerExample1"
}
}
},
{
"fullUrl" : "http://example.org/medication-request-example-kadcyla",
"resource" : {
"resourceType" : "MedicationRequest",
"id" : "medication-request-example-kadcyla",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-request"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationRequest_medication-request-example-kadcyla\"> </a><p><b>Generated Narrative: MedicationRequest</b><a name=\"medication-request-example-kadcyla\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationRequest "medication-request-example-kadcyla" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-request.html\">Cancer-Related Medication Request</a></p></div><p><b>status</b>: active</p><p><b>intent</b>: order</p><p><b>medication</b>: KADCYLA <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#1371046)</span></p><p><b>subject</b>: <a href=\"#Patient_patient-example-kaitlyn-b\">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>authoredOn</b>: 2020-03-12</p><p><b>requester</b>: <a href=\"Practitioner-PractitionerExample1.html\">Practitioner/PractitionerExample1</a> " ANYDOC"</p><p><b>reasonReference</b>: <a href=\"#Condition_KaitlynPrimaryCancerConditionEx1\">See above (Condition/KaitlynPrimaryCancerConditionEx1)</a></p><blockquote><p><b>dosageInstruction</b></p><p><b>text</b>: Kadcyla IV at 3.6mg</p><p><b>timing</b>: Starting 2020-04-01, Once</p><p><b>route</b>: Intravenous route (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#47625008)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote><p><b>maxDosePerAdministration</b>: 1</p></blockquote></div>"
},
"status" : "active",
"intent" : "order",
"medicationCodeableConcept" : {
"coding" : [
{
"system" : "http://www.nlm.nih.gov/research/umls/rxnorm",
"code" : "1371046",
"display" : "KADCYLA"
}
]
},
"subject" : {
🔗 "reference" : "Patient/patient-example-kaitlyn-b"
},
"authoredOn" : "2020-03-12",
"requester" : {
🔗 "reference" : "Practitioner/PractitionerExample1"
},
"reasonReference" : [
{
🔗 "reference" : "Condition/KaitlynPrimaryCancerConditionEx1"
}
],
"dosageInstruction" : [
{
"text" : "Kadcyla IV at 3.6mg",
"timing" : {
"repeat" : {
"boundsPeriod" : {
"start" : "2020-04-01"
}
}
},
"route" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "47625008",
"display" : "Intravenous route (qualifier value)"
}
]
},
"doseAndRate" : [
{
"rateQuantity" : {
"value" : 3.6,
"unit" : "mg",
"system" : "http://unitsofmeasure.org",
"code" : "mg"
}
}
],
"maxDosePerAdministration" : {
"value" : 1
}
}
]
}
},
{
"fullUrl" : "http://example.org/medication-request-example-tucatinib",
"resource" : {
"resourceType" : "MedicationRequest",
"id" : "medication-request-example-tucatinib",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-request"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationRequest_medication-request-example-tucatinib\"> </a><p><b>Generated Narrative: MedicationRequest</b><a name=\"medication-request-example-tucatinib\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationRequest "medication-request-example-tucatinib" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-request.html\">Cancer-Related Medication Request</a></p></div><p><b>status</b>: active</p><p><b>intent</b>: order</p><p><b>medication</b>: tucatinib 150 MG Oral Tablet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#2361290)</span></p><p><b>subject</b>: <a href=\"#Patient_patient-example-kaitlyn-b\">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>authoredOn</b>: 2020-03-12</p><p><b>requester</b>: <a href=\"Practitioner-PractitionerExample1.html\">Practitioner/PractitionerExample1</a> " ANYDOC"</p><p><b>reasonReference</b>: <a href=\"#Condition_KaitlynPrimaryCancerConditionEx1\">See above (Condition/KaitlynPrimaryCancerConditionEx1)</a></p><blockquote><p><b>dosageInstruction</b></p><p><b>text</b>: oral twice a day every day</p><p><b>timing</b>: Starting 2020-04-01, Once</p><p><b>route</b>: Oral route (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#26643006)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote><p><b>maxDosePerAdministration</b>: 2</p></blockquote></div>"
},
"status" : "active",
"intent" : "order",
"medicationCodeableConcept" : {
"coding" : [
{
"system" : "http://www.nlm.nih.gov/research/umls/rxnorm",
"code" : "2361290",
"display" : "tucatinib 150 MG Oral Tablet"
}
]
},
"subject" : {
🔗 "reference" : "Patient/patient-example-kaitlyn-b"
},
"authoredOn" : "2020-03-12",
"requester" : {
🔗 "reference" : "Practitioner/PractitionerExample1"
},
"reasonReference" : [
{
🔗 "reference" : "Condition/KaitlynPrimaryCancerConditionEx1"
}
],
"dosageInstruction" : [
{
"text" : "oral twice a day every day",
"timing" : {
"repeat" : {
"boundsPeriod" : {
"start" : "2020-04-01"
}
}
},
"route" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "26643006",
"display" : "Oral route (qualifier value)"
}
]
},
"doseAndRate" : [
{
"rateQuantity" : {
"value" : 150,
"unit" : "MG",
"system" : "http://unitsofmeasure.org",
"code" : "MG"
}
}
],
"maxDosePerAdministration" : {
"value" : 2
}
}
]
}
},
{
"fullUrl" : "http://example.org/medication-administration-kadcyla",
"resource" : {
"resourceType" : "MedicationAdministration",
"id" : "medication-administration-kadcyla",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-administration"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationAdministration_medication-administration-kadcyla\"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name=\"medication-administration-kadcyla\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationAdministration "medication-administration-kadcyla" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-administration.html\">Cancer-Related Medication Administration</a></p></div><p><b>status</b>: completed</p><p><b>medication</b>: KADCYLA <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#1371046)</span></p><p><b>subject</b>: <a href=\"#Patient_patient-example-kaitlyn-b\">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>effective</b>: 2020-04-01</p><h3>Performers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Actor</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Practitioner-practitioner-oncology-nurse-jane.html\">Practitioner/practitioner-oncology-nurse-jane</a> " NURSE"</td></tr></table><p><b>reasonReference</b>: <a href=\"#Condition_KaitlynPrimaryCancerConditionEx1\">See above (Condition/KaitlynPrimaryCancerConditionEx1)</a></p><p><b>request</b>: <a href=\"#MedicationRequest_medication-request-example-kadcyla\">See above (MedicationRequest/medication-request-example-kadcyla)</a></p><p><b>note</b>: 3.6mg administered by continuous infusion. Patient tolerated infusion without side effects. (By Practitioner/practitioner-oncology-nurse-jane @2020-04-01)</p><h3>Dosages</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Route</b></td><td><b>Dose</b></td></tr><tr><td style=\"display: none\">*</td><td>Intravenous route (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#47625008)</span></td><td>3.6 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg = 'mg')</span></td></tr></table></div>"
},
"status" : "completed",
"medicationCodeableConcept" : {
"coding" : [
{
"system" : "http://www.nlm.nih.gov/research/umls/rxnorm",
"code" : "1371046",
"display" : "KADCYLA"
}
]
},
"subject" : {
🔗 "reference" : "Patient/patient-example-kaitlyn-b"
},
"effectiveDateTime" : "2020-04-01",
"performer" : [
{
"actor" : {
🔗 "reference" : "Practitioner/practitioner-oncology-nurse-jane"
}
}
],
"reasonReference" : [
{
🔗 "reference" : "Condition/KaitlynPrimaryCancerConditionEx1"
}
],
"request" : {
🔗 "reference" : "MedicationRequest/medication-request-example-kadcyla"
},
"note" : [
{
"authorReference" : {
🔗 "reference" : "Practitioner/practitioner-oncology-nurse-jane"
},
"time" : "2020-04-01",
"text" : "3.6mg administered by continuous infusion. Patient tolerated infusion without side effects."
}
],
"dosage" : {
"route" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "47625008",
"display" : "Intravenous route (qualifier value)"
}
]
},
"dose" : {
"value" : 3.6,
"unit" : "mg",
"system" : "http://unitsofmeasure.org",
"code" : "mg"
}
}
}
},
{
"fullUrl" : "http://example.org/medication-administration-tucatinib",
"resource" : {
"resourceType" : "MedicationAdministration",
"id" : "medication-administration-tucatinib",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-administration"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationAdministration_medication-administration-tucatinib\"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name=\"medication-administration-tucatinib\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationAdministration "medication-administration-tucatinib" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-administration.html\">Cancer-Related Medication Administration</a></p></div><p><b>status</b>: completed</p><p><b>medication</b>: tucatinib 150 MG Oral Tablet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#2361290)</span></p><p><b>subject</b>: <a href=\"#Patient_patient-example-kaitlyn-b\">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>effective</b>: 2020-04-01</p><h3>Performers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Actor</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Practitioner-practitioner-oncology-nurse-jane.html\">Practitioner/practitioner-oncology-nurse-jane</a> " NURSE"</td></tr></table><p><b>reasonReference</b>: <a href=\"#Condition_KaitlynPrimaryCancerConditionEx1\">See above (Condition/KaitlynPrimaryCancerConditionEx1)</a></p><p><b>request</b>: <a href=\"#MedicationRequest_medication-request-example-tucatinib\">See above (MedicationRequest/medication-request-example-tucatinib)</a></p><p><b>note</b>: Patient took 2 tablets (By Practitioner/practitioner-oncology-nurse-jane @2020-04-01)</p><h3>Dosages</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Route</b></td><td><b>Dose</b></td></tr><tr><td style=\"display: none\">*</td><td>Oral route (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#26643006)</span></td><td>300 MG<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code MG = 'MG')</span></td></tr></table></div>"
},
"status" : "completed",
"medicationCodeableConcept" : {
"coding" : [
{
"system" : "http://www.nlm.nih.gov/research/umls/rxnorm",
"code" : "2361290",
"display" : "tucatinib 150 MG Oral Tablet"
}
]
},
"subject" : {
🔗 "reference" : "Patient/patient-example-kaitlyn-b"
},
"effectiveDateTime" : "2020-04-01",
"performer" : [
{
"actor" : {
🔗 "reference" : "Practitioner/practitioner-oncology-nurse-jane"
}
}
],
"reasonReference" : [
{
🔗 "reference" : "Condition/KaitlynPrimaryCancerConditionEx1"
}
],
"request" : {
🔗 "reference" : "MedicationRequest/medication-request-example-tucatinib"
},
"note" : [
{
"authorReference" : {
🔗 "reference" : "Practitioner/practitioner-oncology-nurse-jane"
},
"time" : "2020-04-01",
"text" : "Patient took 2 tablets"
}
],
"dosage" : {
"route" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "26643006",
"display" : "Oral route (qualifier value)"
}
]
},
"dose" : {
"value" : 300,
"unit" : "MG",
"system" : "http://unitsofmeasure.org",
"code" : "MG"
}
}
}
},
{
"fullUrl" : "http://example.org/ctc-adverse-event-compass-ex1",
"resource" : {
"resourceType" : "AdverseEvent",
"id" : "ctc-adverse-event-compass-ex1",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctc-adverse-event"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"AdverseEvent_ctc-adverse-event-compass-ex1\"> </a><p><b>Generated Narrative: AdverseEvent</b><a name=\"ctc-adverse-event-compass-ex1\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource AdverseEvent "ctc-adverse-event-compass-ex1" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ctc-adverse-event.html\">CTC Adverse Event</a></p></div><p><b>CTC Adverse Event Grade</b>: Mild Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ctcae-grade-code-system.html\">CTCAE Grade Code System</a>#1)</span></p><blockquote><p><b>Adverse Event Participant</b></p><blockquote><p><b>url</b></p><code>function</code></blockquote><p><b>value</b>: authenticator <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ParticipationType.html\">ParticipationType</a>#AUTHEN)</span></p><blockquote><p><b>url</b></p><code>actor</code></blockquote><p><b>value</b>: <a href=\"Practitioner-us-core-practitioner-owen-oncologist.html\">Practitioner/us-core-practitioner-owen-oncologist</a> " ONCOLOGIST"</p></blockquote><p><b>Adverse Event Expectation</b>: Expected Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C41333)</span></p><p><b>actuality</b>: actual</p><p><b>event</b>: Alanine aminotransferase (ALT) increased at 50 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (MedDRA Am Engl[20.3]#10001551 "Alanine aminotransferase increased")</span></p><p><b>subject</b>: <a href=\"#Patient_patient-example-kaitlyn-b\">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>date</b>: 2020-04-22</p><p><b>seriousness</b>: Non-serious Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C41336)</span></p><p><b>outcome</b>: Ongoing <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R4/codesystem-adverse-event-outcome.html\">AdverseEventOutcome</a>#ongoing)</span></p><p><b>recorder</b>: <a href=\"Practitioner-us-core-practitioner-nancy-oncology-nurse.html\">Practitioner/us-core-practitioner-nancy-oncology-nurse</a> " NURSE"</p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_medication-administration-kadcyla\">See above (MedicationAdministration/medication-administration-kadcyla)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Assessment</b></td></tr><tr><td style=\"display: none\">*</td><td>Adverse Event Probably Related to Intervention <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_medication-administration-tucatinib\">See above (MedicationAdministration/medication-administration-tucatinib)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Assessment</b></td></tr><tr><td style=\"display: none\">*</td><td>Adverse Event Probably Related to Intervention <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><p><b>study</b>: <a href=\"#ResearchStudy_clinical-trial-example-compass\">See above (ResearchStudy/clinical-trial-example-compass)</a></p></div>"
},
"extension" : [
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctcae-grade",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/us/ctcae/CodeSystem/ctcae-grade-code-system",
"code" : "1"
}
]
}
},
{
"extension" : [
{
"url" : "function",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/v3-ParticipationType",
"code" : "AUTHEN"
}
]
}
},
{
"url" : "actor",
"valueReference" : {
🔗 "reference" : "Practitioner/us-core-practitioner-owen-oncologist"
}
}
],
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-participant"
},
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-expectation",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C41333",
"display" : "Expected Adverse Event"
}
]
}
}
],
"actuality" : "actual",
"event" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/MDRAE",
"version" : "20.3",
"code" : "10001551",
"display" : "Alanine aminotransferase increased"
}
],
"text" : "Alanine aminotransferase (ALT) increased at 50"
},
"subject" : {
🔗 "reference" : "Patient/patient-example-kaitlyn-b"
},
"date" : "2020-04-22",
"seriousness" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C41336",
"display" : "Non-serious Adverse Event"
}
]
},
"outcome" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/adverse-event-outcome",
"code" : "ongoing"
}
]
},
"recorder" : {
🔗 "reference" : "Practitioner/us-core-practitioner-nancy-oncology-nurse"
},
"suspectEntity" : [
{
"instance" : {
🔗 "reference" : "MedicationAdministration/medication-administration-kadcyla"
},
"causality" : [
{
"assessment" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C53259"
}
],
"text" : "Adverse Event Probably Related to Intervention"
}
}
]
},
{
"instance" : {
🔗 "reference" : "MedicationAdministration/medication-administration-tucatinib"
},
"causality" : [
{
"assessment" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C53259"
}
],
"text" : "Adverse Event Probably Related to Intervention"
}
}
]
}
],
"study" : [
{
🔗 "reference" : "ResearchStudy/clinical-trial-example-compass"
}
]
}
},
{
"fullUrl" : "http://example.org/ctc-adverse-event-compass-ex1a",
"resource" : {
"resourceType" : "AdverseEvent",
"id" : "ctc-adverse-event-compass-ex1a",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctc-adverse-event"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"AdverseEvent_ctc-adverse-event-compass-ex1a\"> </a><p><b>Generated Narrative: AdverseEvent</b><a name=\"ctc-adverse-event-compass-ex1a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource AdverseEvent "ctc-adverse-event-compass-ex1a" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ctc-adverse-event.html\">CTC Adverse Event</a></p></div><p><b>CTC Adverse Event Grade</b>: Severe Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ctcae-grade-code-system.html\">CTCAE Grade Code System</a>#3)</span></p><blockquote><p><b>Adverse Event Participant</b></p><blockquote><p><b>url</b></p><code>function</code></blockquote><p><b>value</b>: authenticator <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ParticipationType.html\">ParticipationType</a>#AUTHEN)</span></p><blockquote><p><b>url</b></p><code>actor</code></blockquote><p><b>value</b>: <a href=\"Practitioner-us-core-practitioner-owen-oncologist.html\">Practitioner/us-core-practitioner-owen-oncologist</a> " ONCOLOGIST"</p></blockquote><p><b>Adverse Event Expectation</b>: Expected Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C41333)</span></p><p><b>actuality</b>: actual</p><p><b>event</b>: Alanine aminotransferase (ALT) increased to 200 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (MedDRA Am Engl[20.3]#10001551 "Alanine aminotransferase increased")</span></p><p><b>subject</b>: <a href=\"#Patient_patient-example-kaitlyn-b\">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>date</b>: 2020-05-13</p><p><b>seriousness</b>: Non-serious Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C41336)</span></p><p><b>outcome</b>: Ongoing <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R4/codesystem-adverse-event-outcome.html\">AdverseEventOutcome</a>#ongoing)</span></p><p><b>recorder</b>: <a href=\"Practitioner-us-core-practitioner-nancy-oncology-nurse.html\">Practitioner/us-core-practitioner-nancy-oncology-nurse</a> " NURSE"</p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_medication-administration-kadcyla\">See above (MedicationAdministration/medication-administration-kadcyla)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Assessment</b></td></tr><tr><td style=\"display: none\">*</td><td>Adverse Event Probably Related to Intervention <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_medication-administration-tucatinib\">See above (MedicationAdministration/medication-administration-tucatinib)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Assessment</b></td></tr><tr><td style=\"display: none\">*</td><td>Adverse Event Probably Related to Intervention <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><p><b>study</b>: <a href=\"#ResearchStudy_clinical-trial-example-compass\">See above (ResearchStudy/clinical-trial-example-compass)</a></p></div>"
},
"extension" : [
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctcae-grade",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/us/ctcae/CodeSystem/ctcae-grade-code-system",
"code" : "3"
}
]
}
},
{
"extension" : [
{
"url" : "function",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/v3-ParticipationType",
"code" : "AUTHEN"
}
]
}
},
{
"url" : "actor",
"valueReference" : {
🔗 "reference" : "Practitioner/us-core-practitioner-owen-oncologist"
}
}
],
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-participant"
},
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-expectation",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C41333",
"display" : "Expected Adverse Event"
}
]
}
}
],
"actuality" : "actual",
"event" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/MDRAE",
"version" : "20.3",
"code" : "10001551",
"display" : "Alanine aminotransferase increased"
}
],
"text" : "Alanine aminotransferase (ALT) increased to 200"
},
"subject" : {
🔗 "reference" : "Patient/patient-example-kaitlyn-b"
},
"date" : "2020-05-13",
"seriousness" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C41336",
"display" : "Non-serious Adverse Event"
}
]
},
"outcome" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/adverse-event-outcome",
"code" : "ongoing"
}
]
},
"recorder" : {
🔗 "reference" : "Practitioner/us-core-practitioner-nancy-oncology-nurse"
},
"suspectEntity" : [
{
"instance" : {
🔗 "reference" : "MedicationAdministration/medication-administration-kadcyla"
},
"causality" : [
{
"assessment" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C53259"
}
],
"text" : "Adverse Event Probably Related to Intervention"
}
}
]
},
{
"instance" : {
🔗 "reference" : "MedicationAdministration/medication-administration-tucatinib"
},
"causality" : [
{
"assessment" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C53259"
}
],
"text" : "Adverse Event Probably Related to Intervention"
}
}
]
}
],
"study" : [
{
🔗 "reference" : "ResearchStudy/clinical-trial-example-compass"
}
]
}
},
{
"fullUrl" : "http://example.org/ctc-adverse-event-compass-ex1b",
"resource" : {
"resourceType" : "AdverseEvent",
"id" : "ctc-adverse-event-compass-ex1b",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctc-adverse-event"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"AdverseEvent_ctc-adverse-event-compass-ex1b\"> </a><p><b>Generated Narrative: AdverseEvent</b><a name=\"ctc-adverse-event-compass-ex1b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource AdverseEvent "ctc-adverse-event-compass-ex1b" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ctc-adverse-event.html\">CTC Adverse Event</a></p></div><p><b>CTC Adverse Event Grade</b>: Mild Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ctcae-grade-code-system.html\">CTCAE Grade Code System</a>#1)</span></p><blockquote><p><b>Adverse Event Participant</b></p><blockquote><p><b>url</b></p><code>function</code></blockquote><p><b>value</b>: authenticator <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ParticipationType.html\">ParticipationType</a>#AUTHEN)</span></p><blockquote><p><b>url</b></p><code>actor</code></blockquote><p><b>value</b>: <a href=\"Practitioner-us-core-practitioner-owen-oncologist.html\">Practitioner/us-core-practitioner-owen-oncologist</a> " ONCOLOGIST"</p></blockquote><p><b>Adverse Event Expectation</b>: Expected Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C41333)</span></p><p><b>Adverse Event Resolved Date</b>: 2020-06-10</p><p><b>actuality</b>: actual</p><p><b>event</b>: Alanine aminotransferase (ALT) decreased to 60 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (MedDRA Am Engl[20.3]#10001551 "Alanine aminotransferase increased")</span></p><p><b>subject</b>: <a href=\"#Patient_patient-example-kaitlyn-b\">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>date</b>: 2020-05-20</p><p><b>seriousness</b>: Non-serious Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C41336)</span></p><p><b>outcome</b>: Resolved <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R4/codesystem-adverse-event-outcome.html\">AdverseEventOutcome</a>#resolved)</span></p><p><b>recorder</b>: <a href=\"Practitioner-us-core-practitioner-nancy-oncology-nurse.html\">Practitioner/us-core-practitioner-nancy-oncology-nurse</a> " NURSE"</p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_medication-administration-kadcyla\">See above (MedicationAdministration/medication-administration-kadcyla)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Assessment</b></td></tr><tr><td style=\"display: none\">*</td><td>Adverse Event Probably Related to Intervention <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_medication-administration-tucatinib\">See above (MedicationAdministration/medication-administration-tucatinib)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Assessment</b></td></tr><tr><td style=\"display: none\">*</td><td>Adverse Event Probably Related to Intervention <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><p><b>study</b>: <a href=\"#ResearchStudy_clinical-trial-example-compass\">See above (ResearchStudy/clinical-trial-example-compass)</a></p></div>"
},
"extension" : [
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctcae-grade",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/us/ctcae/CodeSystem/ctcae-grade-code-system",
"code" : "1"
}
]
}
},
{
"extension" : [
{
"url" : "function",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/v3-ParticipationType",
"code" : "AUTHEN"
}
]
}
},
{
"url" : "actor",
"valueReference" : {
🔗 "reference" : "Practitioner/us-core-practitioner-owen-oncologist"
}
}
],
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-participant"
},
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-expectation",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C41333",
"display" : "Expected Adverse Event"
}
]
}
},
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-resolved-date",
"valueDateTime" : "2020-06-10"
}
],
"actuality" : "actual",
"event" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/MDRAE",
"version" : "20.3",
"code" : "10001551",
"display" : "Alanine aminotransferase increased"
}
],
"text" : "Alanine aminotransferase (ALT) decreased to 60"
},
"subject" : {
🔗 "reference" : "Patient/patient-example-kaitlyn-b"
},
"date" : "2020-05-20",
"seriousness" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C41336",
"display" : "Non-serious Adverse Event"
}
]
},
"outcome" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/adverse-event-outcome",
"code" : "resolved"
}
]
},
"recorder" : {
🔗 "reference" : "Practitioner/us-core-practitioner-nancy-oncology-nurse"
},
"suspectEntity" : [
{
"instance" : {
🔗 "reference" : "MedicationAdministration/medication-administration-kadcyla"
},
"causality" : [
{
"assessment" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C53259"
}
],
"text" : "Adverse Event Probably Related to Intervention"
}
}
]
},
{
"instance" : {
🔗 "reference" : "MedicationAdministration/medication-administration-tucatinib"
},
"causality" : [
{
"assessment" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C53259"
}
],
"text" : "Adverse Event Probably Related to Intervention"
}
}
]
}
],
"study" : [
{
🔗 "reference" : "ResearchStudy/clinical-trial-example-compass"
}
]
}
},
{
"fullUrl" : "http://example.org/ctc-adverse-event-compass-ex2",
"resource" : {
"resourceType" : "AdverseEvent",
"id" : "ctc-adverse-event-compass-ex2",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctc-adverse-event"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"AdverseEvent_ctc-adverse-event-compass-ex2\"> </a><p><b>Generated Narrative: AdverseEvent</b><a name=\"ctc-adverse-event-compass-ex2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource AdverseEvent "ctc-adverse-event-compass-ex2" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ctc-adverse-event.html\">CTC Adverse Event</a></p></div><p><b>CTC Adverse Event Grade</b>: Mild Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ctcae-grade-code-system.html\">CTCAE Grade Code System</a>#1)</span></p><blockquote><p><b>Adverse Event Participant</b></p><blockquote><p><b>url</b></p><code>function</code></blockquote><p><b>value</b>: authenticator <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ParticipationType.html\">ParticipationType</a>#AUTHEN)</span></p><blockquote><p><b>url</b></p><code>actor</code></blockquote><p><b>value</b>: <a href=\"Practitioner-us-core-practitioner-owen-oncologist.html\">Practitioner/us-core-practitioner-owen-oncologist</a> " ONCOLOGIST"</p></blockquote><p><b>Adverse Event Expectation</b>: Expected Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C41333)</span></p><p><b>Adverse Event Resolved Date</b>: 2021-01-21</p><p><b>actuality</b>: actual</p><p><b>event</b>: Nausea <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (MedDRA Am Engl[20.3]#10028813)</span></p><p><b>subject</b>: <a href=\"#Patient_patient-example-kaitlyn-b\">See above (Patient/patient-example-kaitlyn-b)</a></p><p><b>date</b>: 2020-05-25</p><p><b>seriousness</b>: Non-serious Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C41336)</span></p><p><b>outcome</b>: Ongoing <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R4/codesystem-adverse-event-outcome.html\">AdverseEventOutcome</a>#ongoing)</span></p><p><b>recorder</b>: <a href=\"Practitioner-us-core-practitioner-nancy-oncology-nurse.html\">Practitioner/us-core-practitioner-nancy-oncology-nurse</a> " NURSE"</p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_medication-administration-kadcyla\">See above (MedicationAdministration/medication-administration-kadcyla)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Assessment</b></td></tr><tr><td style=\"display: none\">*</td><td>Adverse Event Possibly Related to Intervention <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C53258)</span></td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_medication-administration-tucatinib\">See above (MedicationAdministration/medication-administration-tucatinib)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Assessment</b></td></tr><tr><td style=\"display: none\">*</td><td>Adverse Event Probably Related to Intervention <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C53259)</span></td></tr></table></blockquote><p><b>study</b>: <a href=\"#ResearchStudy_clinical-trial-example-compass\">See above (ResearchStudy/clinical-trial-example-compass)</a></p></div>"
},
"extension" : [
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctcae-grade",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/us/ctcae/CodeSystem/ctcae-grade-code-system",
"code" : "1"
}
]
}
},
{
"extension" : [
{
"url" : "function",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/v3-ParticipationType",
"code" : "AUTHEN"
}
]
}
},
{
"url" : "actor",
"valueReference" : {
🔗 "reference" : "Practitioner/us-core-practitioner-owen-oncologist"
}
}
],
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-participant"
},
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-expectation",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C41333",
"display" : "Expected Adverse Event"
}
]
}
},
{
"url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-resolved-date",
"valueDateTime" : "2021-01-21"
}
],
"actuality" : "actual",
"event" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/MDRAE",
"version" : "20.3",
"code" : "10028813",
"display" : "Nausea"
}
],
"text" : "Nausea"
},
"subject" : {
🔗 "reference" : "Patient/patient-example-kaitlyn-b"
},
"date" : "2020-05-25",
"seriousness" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C41336",
"display" : "Non-serious Adverse Event"
}
]
},
"outcome" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/adverse-event-outcome",
"code" : "ongoing"
}
]
},
"recorder" : {
🔗 "reference" : "Practitioner/us-core-practitioner-nancy-oncology-nurse"
},
"suspectEntity" : [
{
"instance" : {
🔗 "reference" : "MedicationAdministration/medication-administration-kadcyla"
},
"causality" : [
{
"assessment" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C53258"
}
],
"text" : "Adverse Event Possibly Related to Intervention"
}
}
]
},
{
"instance" : {
🔗 "reference" : "MedicationAdministration/medication-administration-tucatinib"
},
"causality" : [
{
"assessment" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C53259"
}
],
"text" : "Adverse Event Probably Related to Intervention"
}
}
]
}
],
"study" : [
{
🔗 "reference" : "ResearchStudy/clinical-trial-example-compass"
}
]
}
},
{
"fullUrl" : "http://example.org/clinical-trial-example-compass",
"resource" : {
"resourceType" : "ResearchStudy",
"id" : "clinical-trial-example-compass",
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ResearchStudy_clinical-trial-example-compass\"> </a><p><b>Generated Narrative: ResearchStudy</b><a name=\"clinical-trial-example-compass\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ResearchStudy "clinical-trial-example-compass" </p></div><p><b>title</b>: Alliance COMPASS Trial A011801</p><p><b>status</b>: active</p></div>"
},
"title" : "Alliance COMPASS Trial A011801",
"status" : "active"
}
}
]
}