HL7 FHIR Implementation Guide: Common Terminology Criteria (CTC) Adverse Events Release 1 - DRAFT
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HL7 FHIR Implementation Guide: Common Terminology Criteria (CTC) Adverse Events Release 1 - DRAFT, published by HL7 International Clinical Interoperability Council. This guide is not an authorized publication; it is the continuous build for version 0.0.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/standardhealth/fsh-ae/ and changes regularly. See the Directory of published versions

: ae-bundle-persona-2 - JSON Representation

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{
  "resourceType" : "Bundle",
  "id" : "ae-bundle-persona-2",
  "type" : "collection",
  "entry" : [
    {
      "fullUrl" : "http://example.org/PatientPersona2",
      "resource" : {
        "resourceType" : "Patient",
        "id" : "PatientPersona2",
        "meta" : {
          "profile" : [
            🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-patient"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Patient_PatientPersona2\"> </a><p><b>Generated Narrative: Patient</b><a name=\"PatientPersona2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Patient &quot;PatientPersona2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-patient.html\">Cancer Patient</a></p></div><p><b>identifier</b>: Medical Record Number/m456\u00a0(use:\u00a0USUAL)</p><p><b>name</b>: Marsha C. </p><p><b>gender</b>: female</p><p><b>birthDate</b>: 1955-02-20</p><p><b>address</b>: 456 Smith Lane Anytown MA 12345 US </p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Telecom</b></td></tr><tr><td style=\"display: none\">*</td><td>ph: 999-999-9999(HOME), <a href=\"mailto:marsha.c@example.com\">marsha.c@example.com</a></td></tr></table><h3>Communications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Language</b></td></tr><tr><td style=\"display: none\">*</td><td>English <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ietf3066.html\">Tags for the Identification of Languages</a>#en-US &quot;English (Region=United States)&quot;)</span></td></tr></table></div>"
        },
        "identifier" : [
          {
            "use" : "usual",
            "type" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
                  "code" : "MR",
                  "display" : "Medical Record Number"
                }
              ]
            },
            "system" : "http://hospital.example.org",
            "value" : "m456"
          }
        ],
        "name" : [
          {
            "family" : "C.",
            "given" : [
              "Marsha"
            ]
          }
        ],
        "gender" : "female",
        "birthDate" : "1955-02-20",
        "address" : [
          {
            "line" : [
              "456 Smith Lane"
            ],
            "city" : "Anytown",
            "state" : "MA",
            "postalCode" : "12345",
            "country" : "US"
          }
        ],
        "contact" : [
          {
            "telecom" : [
              {
                "system" : "phone",
                "value" : "999-999-9999",
                "use" : "home"
              },
              {
                "system" : "email",
                "value" : "marsha.c@example.com"
              }
            ]
          }
        ],
        "communication" : [
          {
            "language" : {
              "coding" : [
                {
                  "system" : "urn:ietf:bcp:47",
                  "code" : "en-US",
                  "display" : "English (Region=United States)"
                }
              ],
              "text" : "English"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "http://example.org/ctc-adverse-event-anemia1-persona-2",
      "resource" : {
        "resourceType" : "AdverseEvent",
        "id" : "ctc-adverse-event-anemia1-persona-2",
        "meta" : {
          "profile" : [
            🔗 "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctc-adverse-event"
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"AdverseEvent_ctc-adverse-event-anemia1-persona-2\"> </a><p><b>Generated Narrative: AdverseEvent</b><a name=\"ctc-adverse-event-anemia1-persona-2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource AdverseEvent &quot;ctc-adverse-event-anemia1-persona-2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ctc-adverse-event.html\">CTC Adverse Event</a></p></div><p><b>CTC Adverse Event Grade</b>: Moderate Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ctcae-grade-code-system.html\">CTCAE Grade Code System</a>#2)</span></p><p><b>Adverse Event Expectation</b>: Expected Adverse Event <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C41333)</span></p><p><b>Adverse Event Resolved Date</b>: 2020-12-21</p><p><b>actuality</b>: actual</p><p><b>event</b>: Hgb 9.0 per CBC results from 12/21/20 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (MedDRA Am Engl[20.0]#10002272 &quot;Anemia&quot;)</span></p><p><b>subject</b>: <a href=\"#Patient_PatientPersona2\">See above (Patient/PatientPersona2)</a></p><p><b>encounter</b>: <a href=\"#Encounter_encounter-ae1-evaluation-persona2\">See above (Encounter/encounter-ae1-evaluation-persona2)</a></p><p><b>recorder</b>: <a href=\"Practitioner-us-core-practitioner-nancy-oncology-nurse.html\">Practitioner/us-core-practitioner-nancy-oncology-nurse</a> &quot; NURSE&quot;</p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_medadmin-doxorubicin-persona-2\">See above (MedicationAdministration/medadmin-doxorubicin-persona-2)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ProductRelatedness</b></td></tr><tr><td style=\"display: none\">*</td><td>probable</td></tr></table></blockquote><p><b>study</b>: <a href=\"ResearchStudy-clinical-trial-example-soc.html\">ResearchStudy/clinical-trial-example-soc</a></p></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/ctcae-grade",
            "valueCodeableConcept" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/us/ctcae/CodeSystem/ctcae-grade-code-system",
                  "code" : "2",
                  "display" : "Moderate Adverse Event"
                }
              ]
            }
          },
          {
            "url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-expectation",
            "valueCodeableConcept" : {
              "coding" : [
                {
                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                  "code" : "C41333",
                  "display" : "Expected Adverse Event"
                }
              ]
            }
          },
          {
            "url" : "http://hl7.org/fhir/us/ctcae/StructureDefinition/adverse-event-resolved-date",
            "valueDateTime" : "2020-12-21"
          }
        ],
        "actuality" : "actual",
        "event" : {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/MDRAE",
              "version" : "20.0",
              "code" : "10002272",
              "display" : "Anemia"
            }
          ],
          "text" : "Hgb 9.0 per CBC results from 12/21/20"
        },
        "subject" : {
          🔗 "reference" : "Patient/PatientPersona2"
        },
        "encounter" : {
          🔗 "reference" : "Encounter/encounter-ae1-evaluation-persona2"
        },
        "recorder" : {
          🔗 "reference" : "Practitioner/us-core-practitioner-nancy-oncology-nurse"
        },
        "suspectEntity" : [
          {
            "instance" : {
              🔗 "reference" : "MedicationAdministration/medadmin-doxorubicin-persona-2"
            },
            "causality" : [
              {
                "productRelatedness" : "probable"
              }
            ]
          }
        ],
        "study" : [
          {
            🔗 "reference" : "ResearchStudy/clinical-trial-example-soc"
          }
        ]
      }
    },
    {
      "fullUrl" : "http://example.org/primary-cancer-condition-persona-2",
      "resource" : {
        "resourceType" : "Condition",
        "id" : "primary-cancer-condition-persona-2",
        "meta" : {
          "profile" : [
            🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-primary-cancer-condition"
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_primary-cancer-condition-persona-2\"> </a><p><b>Generated Narrative: Condition</b><a name=\"primary-cancer-condition-persona-2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Condition &quot;primary-cancer-condition-persona-2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-primary-cancer-condition.html\">Primary Cancer Condition</a></p></div><p><b>Histology-Morphology-Behavior</b>: Invasive ductal carcinoma with an extensive intraductal component (morphologic abnormality) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#373395001)</span></p><p><b>clinicalStatus</b>: Active <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-condition-clinical.html\">Condition Clinical Status Codes</a>#active)</span></p><p><b>verificationStatus</b>: Confirmed <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-condition-ver-status.html\">ConditionVerificationStatus</a>#confirmed)</span></p><p><b>category</b>: Problem List Item <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-condition-category.html\">Condition Category Codes</a>#problem-list-item)</span></p><p><b>code</b>: Primary malignant neoplasm of female left breast (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#353431000119107)</span></p><p><b>subject</b>: <a href=\"#Patient_PatientPersona2\">See above (Patient/PatientPersona2)</a></p><p><b>onset</b>: 2020-09-25</p><p><b>asserter</b>: <a href=\"Practitioner-us-core-practitioner-owen-oncologist.html\">Practitioner/us-core-practitioner-owen-oncologist</a> &quot; ONCOLOGIST&quot;</p><h3>Stages</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Summary</b></td></tr><tr><td style=\"display: none\">*</td><td>3C <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (cancerstaging.org#3C)</span></td></tr></table></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-histology-morphology-behavior",
            "valueCodeableConcept" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "373395001",
                  "display" : "Invasive ductal carcinoma with an extensive intraductal component (morphologic abnormality)"
                }
              ]
            }
          }
        ],
        "clinicalStatus" : {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/condition-clinical",
              "code" : "active"
            }
          ]
        },
        "verificationStatus" : {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/condition-ver-status",
              "code" : "confirmed"
            }
          ]
        },
        "category" : [
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/condition-category",
                "code" : "problem-list-item"
              }
            ]
          }
        ],
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.info/sct",
              "code" : "353431000119107",
              "display" : "Primary malignant neoplasm of female left breast (disorder)"
            }
          ]
        },
        "subject" : {
          🔗 "reference" : "Patient/PatientPersona2"
        },
        "onsetDateTime" : "2020-09-25",
        "asserter" : {
          🔗 "reference" : "Practitioner/us-core-practitioner-owen-oncologist"
        },
        "stage" : [
          {
            "summary" : {
              "coding" : [
                {
                  "system" : "http://cancerstaging.org",
                  "code" : "3C"
                }
              ]
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "http://example.org/medrequest-doxorubicin-persona-2",
      "resource" : {
        "resourceType" : "MedicationRequest",
        "id" : "medrequest-doxorubicin-persona-2",
        "meta" : {
          "profile" : [
            🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-request"
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationRequest_medrequest-doxorubicin-persona-2\"> </a><p><b>Generated Narrative: MedicationRequest</b><a name=\"medrequest-doxorubicin-persona-2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationRequest &quot;medrequest-doxorubicin-persona-2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-request.html\">Cancer-Related Medication Request</a></p></div><p><b>Treatment Intent</b>: Curative - procedure intent (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#373808002)</span></p><p><b>status</b>: active</p><p><b>intent</b>: order</p><p><b>category</b>: Outpatient <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-medicationrequest-category.html\">MedicationRequest Category Codes</a>#outpatient)</span></p><p><b>medication</b>: DOXOrubicin <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#3639)</span></p><p><b>subject</b>: <a href=\"#Patient_PatientPersona2\">See above (Patient/PatientPersona2)</a></p><p><b>authoredOn</b>: 2020-10-06</p><p><b>requester</b>: <a href=\"Practitioner-us-core-practitioner-owen-oncologist.html\">Practitioner/us-core-practitioner-owen-oncologist</a> &quot; ONCOLOGIST&quot;</p><p><b>reasonReference</b>: <a href=\"#Condition_primary-cancer-condition-persona-2\">See above (Condition/primary-cancer-condition-persona-2)</a></p><blockquote><p><b>dosageInstruction</b></p><p><b>text</b>: doxorubicin (60 mg/m² IV)</p><p><b>timing</b>: Starting 2018-04-01, Once</p><p><b>route</b>: Intravenous route (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#47625008)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote><p><b>maxDosePerPeriod</b>: 1/3 week<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code wk = 'wk')</span></p></blockquote></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-treatment-intent",
            "valueCodeableConcept" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "373808002",
                  "display" : "Curative - procedure intent (qualifier value)"
                }
              ]
            }
          }
        ],
        "status" : "active",
        "intent" : "order",
        "category" : [
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/medicationrequest-category",
                "code" : "outpatient"
              }
            ]
          }
        ],
        "medicationCodeableConcept" : {
          "coding" : [
            {
              "system" : "http://www.nlm.nih.gov/research/umls/rxnorm",
              "code" : "3639",
              "display" : "DOXOrubicin"
            }
          ]
        },
        "subject" : {
          🔗 "reference" : "Patient/PatientPersona2"
        },
        "authoredOn" : "2020-10-06",
        "requester" : {
          🔗 "reference" : "Practitioner/us-core-practitioner-owen-oncologist"
        },
        "reasonReference" : [
          {
            🔗 "reference" : "Condition/primary-cancer-condition-persona-2"
          }
        ],
        "dosageInstruction" : [
          {
            "text" : "doxorubicin (60 mg/m² IV)",
            "timing" : {
              "repeat" : {
                "boundsPeriod" : {
                  "start" : "2018-04-01"
                }
              }
            },
            "route" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "47625008",
                  "display" : "Intravenous route (qualifier value)"
                }
              ]
            },
            "doseAndRate" : [
              {
                "rateQuantity" : {
                  "value" : 60,
                  "unit" : "mg/m2",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "mg/m2"
                }
              }
            ],
            "maxDosePerPeriod" : {
              "numerator" : {
                "value" : 1
              },
              "denominator" : {
                "value" : 3,
                "unit" : "week",
                "system" : "http://unitsofmeasure.org",
                "code" : "wk"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "http://example.org/medadmin-doxorubicin-persona-2",
      "resource" : {
        "resourceType" : "MedicationAdministration",
        "id" : "medadmin-doxorubicin-persona-2",
        "meta" : {
          "profile" : [
            🔗 "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-related-medication-administration"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationAdministration_medadmin-doxorubicin-persona-2\"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name=\"medadmin-doxorubicin-persona-2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationAdministration &quot;medadmin-doxorubicin-persona-2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/us/mcode/2021May/StructureDefinition-mcode-cancer-related-medication-administration.html\">Cancer-Related Medication Administration</a></p></div><p><b>status</b>: completed</p><p><b>category</b>: Outpatient <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-medicationrequest-category.html\">MedicationRequest Category Codes</a>#outpatient)</span></p><p><b>medication</b>: doxorubicin hydrochloride 20 MG per 10 ML Injection <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#1790099)</span></p><p><b>subject</b>: <a href=\"#Patient_PatientPersona2\">See above (Patient/PatientPersona2)</a></p><p><b>effective</b>: 2020-12-01</p><p><b>reasonReference</b>: <a href=\"#Condition_primary-cancer-condition-persona-2\">See above (Condition/primary-cancer-condition-persona-2)</a></p><p><b>request</b>: <a href=\"#MedicationRequest_medrequest-doxorubicin-persona-2\">See above (MedicationRequest/medrequest-doxorubicin-persona-2)</a></p><p><b>note</b>: doxorubicin (60 mg/m² IV), 105.96 mg in 50 ml 0.9% normal saline administered by continuous infusion. Patient tolerated infusion without side effects. (By Practitioner/us-core-practitioner-nancy-oncology-nurse @2020-12-01)</p><h3>Dosages</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Route</b></td><td><b>Dose</b></td></tr><tr><td style=\"display: none\">*</td><td>Intravenous route (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#47625008)</span></td><td>105.96 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg = 'mg')</span></td></tr></table></div>"
        },
        "status" : "completed",
        "category" : {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/medicationrequest-category",
              "code" : "outpatient"
            }
          ]
        },
        "medicationCodeableConcept" : {
          "coding" : [
            {
              "system" : "http://www.nlm.nih.gov/research/umls/rxnorm",
              "code" : "1790099",
              "display" : "doxorubicin hydrochloride 20 MG per 10 ML Injection"
            }
          ]
        },
        "subject" : {
          🔗 "reference" : "Patient/PatientPersona2"
        },
        "effectiveDateTime" : "2020-12-01",
        "reasonReference" : [
          {
            🔗 "reference" : "Condition/primary-cancer-condition-persona-2"
          }
        ],
        "request" : {
          🔗 "reference" : "MedicationRequest/medrequest-doxorubicin-persona-2"
        },
        "note" : [
          {
            "authorReference" : {
              🔗 "reference" : "Practitioner/us-core-practitioner-nancy-oncology-nurse"
            },
            "time" : "2020-12-01",
            "text" : "doxorubicin (60 mg/m² IV), 105.96 mg in 50 ml 0.9% normal saline administered by continuous infusion. Patient tolerated infusion without side effects."
          }
        ],
        "dosage" : {
          "route" : {
            "coding" : [
              {
                "system" : "http://snomed.info/sct",
                "code" : "47625008",
                "display" : "Intravenous route (qualifier value)"
              }
            ]
          },
          "dose" : {
            "value" : 105.96,
            "unit" : "mg",
            "system" : "http://unitsofmeasure.org",
            "code" : "mg"
          }
        }
      }
    },
    {
      "fullUrl" : "http://example.org/diagnosticreport-cbc-201-1-persona2",
      "resource" : {
        "resourceType" : "DiagnosticReport",
        "id" : "201",
        "meta" : {
          "tag" : [
            {
              "system" : "http://example.org/fhir/CodeSystem/workflow-codes",
              "code" : "01",
              "display" : "Needs Review"
            }
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_201\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"201\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport &quot;201&quot; </p><p style=\"margin-bottom: 0px\">Tag: <span title=\"{http://example.org/fhir/CodeSystem/workflow-codes http://example.org/fhir/CodeSystem/workflow-codes}\">http://example.org/fhir/CodeSystem/workflow-codes</span></p></div><p><b>identifier</b>: <code>http://acme.com/lab/reports</code>/5234342</p><p><b>status</b>: final</p><p><b>category</b>: Hematology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v2-0074.html\">diagnosticServiceSectionId</a>#HM)</span></p><p><b>code</b>: Complete Blood Count <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#58410-2 &quot;CBC panel - Blood by Automated count&quot;)</span></p><p><b>subject</b>: <a href=\"#Patient_PatientPersona2\">See above (Patient/PatientPersona2)</a></p><p><b>effective</b>: 2020-12-21 08:30:00+1100</p><p><b>issued</b>: Dec 21, 2020, 12:45:33\u202fAM</p><p><b>result</b>: </p><ul><li><a href=\"Observation-r201-1.html\">Observation/r201-1</a></li><li><a href=\"Observation-r201-2.html\">Observation/r201-2</a></li><li><a href=\"Observation-r201-3.html\">Observation/r201-3</a></li><li><a href=\"Observation-r201-4.html\">Observation/r201-4</a></li><li><a href=\"Observation-r201-5.html\">Observation/r201-5</a></li><li><a href=\"Observation-r201-6.html\">Observation/r201-6</a></li><li><a href=\"Observation-r201-7.html\">Observation/r201-7</a></li><li><a href=\"Observation-r201-8.html\">Observation/r201-8</a></li><li><a href=\"Observation-r201-9.html\">Observation/r201-9</a></li><li><a href=\"Observation-r201-10.html\">Observation/r201-10</a></li><li><a href=\"Observation-r201-11.html\">Observation/r201-11</a></li><li><a href=\"Observation-r201-12.html\">Observation/r201-12</a></li><li><a href=\"Observation-r201-13.html\">Observation/r201-13</a></li><li><a href=\"Observation-r201-14.html\">Observation/r201-14</a></li><li><a href=\"Observation-r201-15.html\">Observation/r201-15</a></li><li><a href=\"Observation-r201-16.html\">Observation/r201-16</a></li><li><a href=\"Observation-r201-17.html\">Observation/r201-17</a></li></ul></div>"
        },
        "identifier" : [
          {
            "system" : "http://acme.com/lab/reports",
            "value" : "5234342"
          }
        ],
        "status" : "final",
        "category" : [
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/v2-0074",
                "code" : "HM"
              }
            ]
          }
        ],
        "code" : {
          "coding" : [
            {
              "system" : "http://loinc.org",
              "code" : "58410-2",
              "display" : "CBC panel - Blood by Automated count"
            }
          ],
          "text" : "Complete Blood Count"
        },
        "subject" : {
          🔗 "reference" : "Patient/PatientPersona2"
        },
        "effectiveDateTime" : "2020-12-21T08:30:00+11:00",
        "issued" : "2020-12-21T11:45:33+11:00",
        "result" : [
          {
            🔗 "reference" : "Observation/r201-1"
          },
          {
            🔗 "reference" : "Observation/r201-2"
          },
          {
            🔗 "reference" : "Observation/r201-3"
          },
          {
            🔗 "reference" : "Observation/r201-4"
          },
          {
            🔗 "reference" : "Observation/r201-5"
          },
          {
            🔗 "reference" : "Observation/r201-6"
          },
          {
            🔗 "reference" : "Observation/r201-7"
          },
          {
            🔗 "reference" : "Observation/r201-8"
          },
          {
            🔗 "reference" : "Observation/r201-9"
          },
          {
            🔗 "reference" : "Observation/r201-10"
          },
          {
            🔗 "reference" : "Observation/r201-11"
          },
          {
            🔗 "reference" : "Observation/r201-12"
          },
          {
            🔗 "reference" : "Observation/r201-13"
          },
          {
            🔗 "reference" : "Observation/r201-14"
          },
          {
            🔗 "reference" : "Observation/r201-15"
          },
          {
            🔗 "reference" : "Observation/r201-16"
          },
          {
            🔗 "reference" : "Observation/r201-17"
          }
        ]
      }
    },
    {
      "fullUrl" : "http://example.org/diagnosticreport-cbc-202-1-persona2",
      "resource" : {
        "resourceType" : "DiagnosticReport",
        "id" : "202",
        "meta" : {
          "tag" : [
            {
              "system" : "http://example.org/fhir/CodeSystem/workflow-codes",
              "code" : "01",
              "display" : "Needs Review"
            }
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_202\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"202\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport &quot;202&quot; </p><p style=\"margin-bottom: 0px\">Tag: <span title=\"{http://example.org/fhir/CodeSystem/workflow-codes http://example.org/fhir/CodeSystem/workflow-codes}\">http://example.org/fhir/CodeSystem/workflow-codes</span></p></div><p><b>identifier</b>: <code>http://acme.com/lab/reports</code>/5234342</p><p><b>status</b>: final</p><p><b>category</b>: Hematology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v2-0074.html\">diagnosticServiceSectionId</a>#HM)</span></p><p><b>code</b>: Complete Blood Count <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#58410-2 &quot;CBC panel - Blood by Automated count&quot;)</span></p><p><b>subject</b>: <a href=\"#Patient_PatientPersona2\">See above (Patient/PatientPersona2)</a></p><p><b>effective</b>: 2020-12-29 08:30:00+1100</p><p><b>issued</b>: Dec 29, 2020, 12:45:33\u202fAM</p><p><b>result</b>: </p><ul><li><a href=\"Observation-r202-1.html\">Observation/r202-1</a></li><li><a href=\"Observation-r202-2.html\">Observation/r202-2</a></li><li><a href=\"Observation-r202-3.html\">Observation/r202-3</a></li><li><a href=\"Observation-r202-4.html\">Observation/r202-4</a></li><li><a href=\"Observation-r202-5.html\">Observation/r202-5</a></li><li><a href=\"Observation-r202-6.html\">Observation/r202-6</a></li><li><a href=\"Observation-r202-7.html\">Observation/r202-7</a></li><li><a href=\"Observation-r202-8.html\">Observation/r202-8</a></li><li><a href=\"Observation-r202-9.html\">Observation/r202-9</a></li><li><a href=\"Observation-r202-10.html\">Observation/r202-10</a></li><li><a href=\"Observation-r202-11.html\">Observation/r202-11</a></li><li><a href=\"Observation-r202-12.html\">Observation/r202-12</a></li><li><a href=\"Observation-r202-13.html\">Observation/r202-13</a></li><li><a href=\"Observation-r202-14.html\">Observation/r202-14</a></li><li><a href=\"Observation-r202-15.html\">Observation/r202-15</a></li><li><a href=\"Observation-r202-16.html\">Observation/r202-16</a></li><li><a href=\"Observation-r202-17.html\">Observation/r202-17</a></li></ul></div>"
        },
        "identifier" : [
          {
            "system" : "http://acme.com/lab/reports",
            "value" : "5234342"
          }
        ],
        "status" : "final",
        "category" : [
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/v2-0074",
                "code" : "HM"
              }
            ]
          }
        ],
        "code" : {
          "coding" : [
            {
              "system" : "http://loinc.org",
              "code" : "58410-2",
              "display" : "CBC panel - Blood by Automated count"
            }
          ],
          "text" : "Complete Blood Count"
        },
        "subject" : {
          🔗 "reference" : "Patient/PatientPersona2"
        },
        "effectiveDateTime" : "2020-12-29T08:30:00+11:00",
        "issued" : "2020-12-29T11:45:33+11:00",
        "result" : [
          {
            🔗 "reference" : "Observation/r202-1"
          },
          {
            🔗 "reference" : "Observation/r202-2"
          },
          {
            🔗 "reference" : "Observation/r202-3"
          },
          {
            🔗 "reference" : "Observation/r202-4"
          },
          {
            🔗 "reference" : "Observation/r202-5"
          },
          {
            🔗 "reference" : "Observation/r202-6"
          },
          {
            🔗 "reference" : "Observation/r202-7"
          },
          {
            🔗 "reference" : "Observation/r202-8"
          },
          {
            🔗 "reference" : "Observation/r202-9"
          },
          {
            🔗 "reference" : "Observation/r202-10"
          },
          {
            🔗 "reference" : "Observation/r202-11"
          },
          {
            🔗 "reference" : "Observation/r202-12"
          },
          {
            🔗 "reference" : "Observation/r202-13"
          },
          {
            🔗 "reference" : "Observation/r202-14"
          },
          {
            🔗 "reference" : "Observation/r202-15"
          },
          {
            🔗 "reference" : "Observation/r202-16"
          },
          {
            🔗 "reference" : "Observation/r202-17"
          }
        ]
      }
    },
    {
      "fullUrl" : "http://example.org/encounter-ae1-evaluation-persona2",
      "resource" : {
        "resourceType" : "Encounter",
        "id" : "encounter-ae1-evaluation-persona2",
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Encounter_encounter-ae1-evaluation-persona2\"> </a><p><b>Generated Narrative: Encounter</b><a name=\"encounter-ae1-evaluation-persona2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Encounter &quot;encounter-ae1-evaluation-persona2&quot; </p></div><p><b>status</b>: finished</p><p><b>class</b>: ambulatory (Details: http://terminology.hl7.org/CodeSystem/v3-ActCode code AMB = 'ambulatory', stated as 'ambulatory')</p><p><b>subject</b>: <a href=\"#Patient_PatientPersona2\">See above (Patient/PatientPersona2)</a></p><p><b>period</b>: 2020-12-01 --&gt; 2020-12-01</p></div>"
        },
        "status" : "finished",
        "class" : {
          "system" : "http://terminology.hl7.org/CodeSystem/v3-ActCode",
          "code" : "AMB",
          "display" : "ambulatory"
        },
        "subject" : {
          🔗 "reference" : "Patient/PatientPersona2"
        },
        "period" : {
          "start" : "2020-12-01",
          "end" : "2020-12-01"
        }
      }
    }
  ]
}