{
  "resourceType" : "Observation",
  "id" : "PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu",
  "meta" : {
    "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.1"]
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu</b></p><a name=\"PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu\"> </a><a name=\"hcPatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-mii-pr-mtb-immunohistochemistry.html\">MII PR MTB Immunohistochemistryversion: null2026.0.1)</a></p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v2-0074 GE}\">Genetik</span>, <span title=\"Codes:{http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs biomarker-category}\">A characterization of a given biomarker observation.</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 18474-7}, {http://snomed.info/sct 1234806008}\">HER2 Ag [Presence] in Tissue by Immune stain</span></p><p><b>subject</b>: <a href=\"Patient-PatientKimMusterperson.html\">Kim Musterperson  (no stated gender), DoB: 1956-03-14</a></p><p><b>value</b>: <span title=\"Codes:{http://loinc.org LA11842-4}\">2+</span></p><p><b>specimen</b>: <a href=\"Specimen-PatientKimMusterperson-AscitesSpecimen-2.html\">Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen)</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:3430}\">ERBB2</span></td></tr></table></div>"
  },
  "status" : "final",
  "category" : [{
    "coding" : [{
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      "code" : "laboratory"
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  {
    "coding" : [{
      "system" : "http://terminology.hl7.org/CodeSystem/v2-0074",
      "code" : "GE"
    }]
  },
  {
    "coding" : [{
      "system" : "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs",
      "code" : "biomarker-category"
    }]
  }],
  "code" : {
    "coding" : [{
      "system" : "http://loinc.org",
      "code" : "18474-7",
      "display" : "HER2 Ag [Presence] in Tissue by Immune stain"
    },
    {
      "system" : "http://snomed.info/sct",
      "code" : "1234806008",
      "display" : "Observation using immunohistochemistry (observable entity)"
    }]
  },
  "subject" : {
    "reference" : "Patient/PatientKimMusterperson"
  },
  "valueCodeableConcept" : {
    "coding" : [{
      "system" : "http://loinc.org",
      "code" : "LA11842-4",
      "display" : "2+"
    }]
  },
  "specimen" : {
    "reference" : "Specimen/PatientKimMusterperson-AscitesSpecimen-2"
  },
  "component" : [{
    "code" : {
      "coding" : [{
        "system" : "http://loinc.org",
        "code" : "48018-6",
        "display" : "Gene studied [ID]"
      }]
    },
    "valueCodeableConcept" : {
      "coding" : [{
        "system" : "http://www.genenames.org/geneId",
        "code" : "HGNC:3430",
        "display" : "ERBB2"
      }]
    }
  }]
}