/* Instance: MII-EXA-MTB-Immunohistochemistry-PDL1 InstanceOf: MII_PR_MTB_Immunohistochemistry_PDL1 Usage: #example Title: "Beispiel PDL1 Immunohistochemie" Description: "Beispiel fuer PDL1 Immunhistochemie mit Berechnung der relvanten Scores" * meta.profile = "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunhistochemistry-pdl1" * status = #final * category[labCategory] = $fhir-observation-category#laboratory "Laboratory" * code = $SCT#1234806008 "Observation using immunohistochemistry (observable entity)" * subject = Reference(Patient/example) * encounter = Reference(Encounter/example) * valueQuantity = 2.61 $UCUM#% * specimen = Reference(Specimen/example) * component[gene-studied].valueCodeableConcept = $HGNC#HGNC:17635 "PD-L1" // eigentlich CD274 * component[tps-score].code = $NCIT#C184941 "PD-L1 Tumor Proportion Score" * component[tps-score].valueQuantity = 5 $UCUM#% "TPS Score" * component[cps-score].code = $NCIT#C176582 "PD-L1 Combined Positive Score" * component[cps-score].valueQuantity = 10 $UCUM#% "CPS Score" * component[ips-score].code = $NCIT#C184941 "PD-L1 Tumor Proportion Score" * component[ics-score].valueQuantity = 15 $UCUM#% "ICS Score" * component[tc-score].code = $LNC#83053-9 "Cells.programmed cell death ligand 1/Viable tumor cells in Tissue by Immune stain" * component[tc-score].valueQuantity = 20 $UCUM#% "TC Score" */