Medication IG DE
1.0.3 - STU1

Medication IG DE, published by HL7 Deutschland e.V.. This guide is not an authorized publication; it is the continuous build for version 1.0.3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7germany/medication-ig-de-r4/ and changes regularly. See the Directory of published versions

## Data Type Profile: DosageDE - XML Profile

Active as of 2025-11-19

XML representation of the DosageDE data type profile.

Raw xml | Download

    <StructureDefinition xmlns="http://hl7.org/fhir">
      <id value="DosageDE"/>
      <text>
        <status value="extensions"/>
        <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: StructureDefinition DosageDE</b></p><a name="DosageDE"> </a><a name="hcDosageDE"> </a><table border="0" cellpadding="0" cellspacing="0" style="border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;"><tr style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top"><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="The logical name of the element">Name</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Information about the use of the element">Flags</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Minimum and Maximum # of times the element can appear in the instance">Card.</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px; width: 100px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Reference to the type of the element">Type</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Additional information about the element">Description &amp; Constraints</a><span style="float: right"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format"><img src="data:image/png;base64, " alt="doco" style="background-color: inherit"/></a></span></th></tr><tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_element.gif" alt="." style="background-color: white; background-color: inherit" title="Element" class="hierarchy"/> <a href="StructureDefinition-DosageDE-definitions.html#Dosage">Dosage</a><a name="Dosage"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a style="padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold; color: #301212; background-color: #fdf4f4;; padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold; color: #301212; background-color: #fdf4f4;" href="http://hl7.org/fhir/R4/conformance-rules.html#constraints" title="This element has or is affected by constraints ( DosageStructuredOrFreeTextWarning, DosageStructuredRequiresBoth, DosageDoseUnitSameCode, DosageWarnungViererschemaInText, FreeTextSingleDosageOnlyWarning )">C</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5">0</span><span style="opacity: 0.5">..</span><span style="opacity: 0.5">*</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#Dosage">Dosage</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5">How the medication is/was taken or should be taken</span><br class="constraint"/><span title="null" class="constraint">Constraints: </span><span style="font-weight:bold" title="Die Dosierungsangabe darf entweder nur als Freitext oder nur als vollständige strukturierte Information erfolgen — eine Mischung ist nicht erlaubt." class="constraint">DosageStructuredOrFreeTextWarning</span><span title="null" class="constraint">, </span><span style="font-weight:bold" title="Wenn eine strukturierte Dosierungsangabe erfolgt, müssen sowohl timing als auch doseAndRate angegeben werden." class="constraint">DosageStructuredRequiresBoth</span><span title="null" class="constraint">, </span><span style="font-weight:bold" title="Die Dosiereinheit muss über alle Dosierungen gleich sein." class="constraint">DosageDoseUnitSameCode</span><span title="null" class="constraint">, </span><span style="font-weight:bold" title="Hinweis: In Dosage.text wurde ein Viererschema (z. B. 1-1-1-1) erkannt. Bitte prüfen, ob dies strukturiert abgebildet werden kann." class="constraint">DosageWarnungViererschemaInText</span><span title="null" class="constraint">, </span><span style="font-weight:bold" title="Wenn eine Dosierung als reiner Freitext angegeben ist, soll nur genau ein Dosage-Element existieren." class="constraint">FreeTextSingleDosageOnlyWarning</span></td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_element.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Element" class="hierarchy"/> <a href="StructureDefinition-DosageDE-definitions.html#Dosage.text" title="Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Stück bei Bedarf'. Als Quelle dient hier ausschließlich der Arzt oder Apotheker">text</a><a name="Dosage.text"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element must be supported">S</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5">0</span><span style="opacity: 0.5">..</span><span style="opacity: 0.5">1</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a style="opacity: 0.5; opacity: 0.5" href="http://hl7.org/fhir/R4/datatypes.html#string">string</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Stück bei Bedarf'</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-DosageDE-definitions.html#Dosage.timing" title="Wann das Medikament verabreicht werden soll.">timing</a><a name="Dosage.timing"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element must be supported">S</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5">0</span><span style="opacity: 0.5">..</span><span style="opacity: 0.5">1</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="StructureDefinition-TimingDE.html" title="Timing">TimingDE</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Wann das Medikament verabreicht werden soll</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_element.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Element" class="hierarchy"/> <a href="StructureDefinition-DosageDE-definitions.html#Dosage.doseAndRate" title="Die verabreichte Menge des Medikaments.">doseAndRate</a><a name="Dosage.doseAndRate"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element must be supported">S</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5">0</span><span style="opacity: 0.5">..</span><span style="opacity: 0.5">*</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5">Element</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Menge des verabreichten Medikaments</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck003.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_slice.png" alt="." style="background-color: white; background-color: inherit" title="Slice Definition" class="hierarchy"/> <a style="font-style: italic; font-style: italic" href="StructureDefinition-DosageDE-definitions.html#Dosage.doseAndRate.dose[x]">Slices for dose[x]</a><a name="Dosage.doseAndRate.dose_x_"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="font-style: italic"/><span style="opacity: 0.5; font-style: italic">0</span><span style="opacity: 0.5; font-style: italic">..</span><span style="opacity: 0.5; font-style: italic">1</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a style="opacity: 0.5; font-style: italic; opacity: 0.5; font-style: italic" href="http://hl7.org/fhir/R4/datatypes.html#Range">Range</a><span style="opacity: 0.5; font-style: italic">, </span><a style="opacity: 0.5; font-style: italic; opacity: 0.5; font-style: italic" href="http://hl7.org/fhir/R4/datatypes.html#SimpleQuantity" title="Quantity">SimpleQuantity(4.0.1)</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5; font-style: italic">Amount of medication per dose</span><br style="font-style: italic"/><span style="font-weight:bold; font-style: italic">Slice: </span><span style="font-style: italic">Unordered, Open by type:$this</span></td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0024.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end_slicer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_slice_item.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Slice Item" class="hierarchy"/> <a href="StructureDefinition-DosageDE-definitions.html#Dosage.doseAndRate.dose[x]:doseQuantity" title="Slice doseQuantity: Menge des Medikaments pro Dosis.">dose[x]:doseQuantity</a><a name="Dosage.doseAndRate.dose_x_.2"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element must be supported">S</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#SimpleQuantity" title="Quantity">SimpleQuantity</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Menge des Medikaments pro Dosis<br class="binding"/><span style="font-weight:bold" title="null" class="binding">Binding: </span><a href="ValueSet-DosageDoseQuantityDE.html" title="http://ig.fhir.de/igs/medication/ValueSet/DosageDoseQuantityDE" class="binding">Dosage DoseQuantity ValueSet</a><span title="null" class="binding"> (</span><a href="http://hl7.org/fhir/R4/terminologies.html#required" title="To be conformant, the concept in this element SHALL be from the specified value set." class="binding">required</a><span title="null" class="binding">)</span></td></tr>
    <tr><td colspan="5" class="hierarchy"><br/><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format"><img src="data:image/png;base64, " alt="doco" style="background-color: inherit"/> Documentation for this format</a></td></tr></table></div>
      </text>
      <url value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
      <version value="1.0.3"/>
      <name value="DosageDE"/>
      <title value="Dosage DE"/>
      <status value="active"/>
      <date value="2025-11-19T15:42:47+00:00"/>
      <publisher value="HL7 Deutschland e.V."/>
      <contact>
        <name value="HL7 Deutschland e.V."/>
        <telecom>
          <system value="url"/>
          <value value="https://hl7.de"/>
        </telecom>
      </contact>
      <description
                   value="Gibt an, wie das Medikament eingenommen oder verabreicht wurde bzw. eingenommen oder verabreicht werden soll - entweder selbst vom Patienten eingenommen oder bei Fremdverabreichung von Dritten (z. B. Leistungserbringer, Angehörige) verabreicht."/>
      <fhirVersion value="4.0.1"/>
      <mapping>
        <identity value="rim"/>
        <uri value="http://hl7.org/v3"/>
        <name value="RIM Mapping"/>
      </mapping>
      <mapping>
        <identity value="v2"/>
        <uri value="http://hl7.org/v2"/>
        <name value="HL7 v2 Mapping"/>
      </mapping>
      <kind value="complex-type"/>
      <abstract value="false"/>
      <type value="Dosage"/>
      <baseDefinition value="http://hl7.org/fhir/StructureDefinition/Dosage"/>
      <derivation value="constraint"/>
      <snapshot>
        <extension
                   url="http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version">
          <valueString value="4.0.1"/>
        </extension>
        <element id="Dosage">
          <path value="Dosage"/>
          <short value="How the medication is/was taken or should be taken"/>
          <definition
                      value="Indicates how the medication is/was taken or should be taken by the patient."/>
          <min value="0"/>
          <max value="*"/>
          <base>
            <path value="Dosage"/>
            <min value="0"/>
            <max value="*"/>
          </base>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <constraint>
            <key value="DosageStructuredOrFreeTextWarning"/>
            <severity value="warning"/>
            <human
                   value="Die Dosierungsangabe darf entweder nur als Freitext oder nur als vollständige strukturierte Information erfolgen — eine Mischung ist nicht erlaubt."/>
            <expression
                        value="(%resource.ofType(MedicationRequest).dosageInstruction |
     ofType(MedicationDispense).dosageInstruction |
     ofType(MedicationStatement).dosage).all(
      (text.exists() and timing.empty() and doseAndRate.empty()) or
      (text.empty() and (timing.exists() or doseAndRate.exists()))
    )
    "/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
          <constraint>
            <key value="DosageStructuredRequiresBoth"/>
            <severity value="error"/>
            <human
                   value="Wenn eine strukturierte Dosierungsangabe erfolgt, müssen sowohl timing als auch doseAndRate angegeben werden."/>
            <expression
                        value="(%resource.ofType(MedicationRequest).dosageInstruction |
     ofType(MedicationDispense).dosageInstruction |
     ofType(MedicationStatement).dosage).all(
      (timing.exists() implies doseAndRate.exists()) and
      (doseAndRate.exists() implies timing.exists())
    )
    "/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
          <constraint>
            <key value="DosageDoseUnitSameCode"/>
            <severity value="error"/>
            <human
                   value="Die Dosiereinheit muss über alle Dosierungen gleich sein."/>
            <expression
                        value="(%resource.ofType(MedicationRequest).dosageInstruction | ofType(MedicationDispense).dosageInstruction | ofType(MedicationStatement).dosage).all(
    doseAndRate.exists() implies
      (
        %resource.dosageInstruction.doseAndRate.dose.ofType(Quantity).code |
        %resource.dosageInstruction.doseAndRate.dose.ofType(Range).low.code |
        %resource.dosageInstruction.doseAndRate.dose.ofType(Range).high.code
      ).distinct().count() = 1
    )"/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
          <constraint>
            <key value="DosageWarnungViererschemaInText"/>
            <severity value="warning"/>
            <human
                   value="Hinweis: In Dosage.text wurde ein Viererschema (z. B. 1-1-1-1) erkannt. Bitte prüfen, ob dies strukturiert abgebildet werden kann."/>
            <expression
                        value="text.exists() implies text.matches('.*\\d+\\s*[-–]\\s*\\d+\\s*[-–]\\s*\\d+\\s*[-–]\\d+.*').not()"/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
          <constraint>
            <key value="FreeTextSingleDosageOnlyWarning"/>
            <severity value="warning"/>
            <human
                   value="Wenn eine Dosierung als reiner Freitext angegeben ist, soll nur genau ein Dosage-Element existieren."/>
            <expression
                        value="(
      (%resource.ofType(MedicationRequest).dosageInstruction |
       %resource.ofType(MedicationDispense).dosageInstruction |
       %resource.ofType(MedicationStatement).dosage
      ).exists(text.exists() and timing.empty() and doseAndRate.empty())
    )
    implies
    (
      (%resource.ofType(MedicationRequest).dosageInstruction |
       %resource.ofType(MedicationDispense).dosageInstruction |
       %resource.ofType(MedicationStatement).dosage
      ).count() = 1
    )"/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
          <isModifier value="false"/>
          <mapping>
            <identity value="rim"/>
            <map value="n/a"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map
                 value=".outboundRelationship[typeCode=COMP].target[classCode=SBADM, moodCode=INT]"/>
          </mapping>
        </element>
        <element id="Dosage.id">
          <path value="Dosage.id"/>
          <representation value="xmlAttr"/>
          <short value="Unique id for inter-element referencing"/>
          <definition
                      value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Element.id"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
              <valueUrl value="string"/>
            </extension>
            <code value="http://hl7.org/fhirpath/System.String"/>
          </type>
          <isModifier value="false"/>
          <isSummary value="false"/>
          <mapping>
            <identity value="rim"/>
            <map value="n/a"/>
          </mapping>
        </element>
        <element id="Dosage.extension">
          <path value="Dosage.extension"/>
          <slicing>
            <discriminator>
              <type value="value"/>
              <path value="url"/>
            </discriminator>
            <description value="Extensions are always sliced by (at least) url"/>
            <rules value="open"/>
          </slicing>
          <short value="Additional content defined by implementations"/>
          <definition
                      value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
          <comment
                   value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
          <alias value="extensions"/>
          <alias value="user content"/>
          <min value="0"/>
          <max value="*"/>
          <base>
            <path value="Element.extension"/>
            <min value="0"/>
            <max value="*"/>
          </base>
          <type>
            <code value="Extension"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <constraint>
            <key value="ext-1"/>
            <severity value="error"/>
            <human value="Must have either extensions or value[x], not both"/>
            <expression value="extension.exists() != value.exists()"/>
            <xpath
                   value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Extension"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="false"/>
          <mapping>
            <identity value="rim"/>
            <map value="n/a"/>
          </mapping>
        </element>
        <element id="Dosage.modifierExtension">
          <path value="Dosage.modifierExtension"/>
          <short value="Extensions that cannot be ignored even if unrecognized"/>
          <definition
                      value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

    Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)."/>
          <comment
                   value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
          <requirements
                        value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)."/>
          <alias value="extensions"/>
          <alias value="user content"/>
          <alias value="modifiers"/>
          <min value="0"/>
          <max value="*"/>
          <base>
            <path value="BackboneElement.modifierExtension"/>
            <min value="0"/>
            <max value="*"/>
          </base>
          <type>
            <code value="Extension"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <constraint>
            <key value="ext-1"/>
            <severity value="error"/>
            <human value="Must have either extensions or value[x], not both"/>
            <expression value="extension.exists() != value.exists()"/>
            <xpath
                   value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Extension"/>
          </constraint>
          <isModifier value="true"/>
          <isModifierReason
                            value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="rim"/>
            <map value="N/A"/>
          </mapping>
        </element>
        <element id="Dosage.sequence">
          <path value="Dosage.sequence"/>
          <short value="The order of the dosage instructions"/>
          <definition
                      value="Indicates the order in which the dosage instructions should be applied or interpreted."/>
          <requirements
                        value="If the sequence number of multiple Dosages is the same, then it is implied that the instructions are to be treated as concurrent.  If the sequence number is different, then the Dosages are intended to be sequential."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.sequence"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="integer"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="v2"/>
            <map value="TQ1-1"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".text"/>
          </mapping>
        </element>
        <element id="Dosage.text">
          <path value="Dosage.text"/>
          <short
                 value="Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Stück bei Bedarf'"/>
          <definition
                      value="Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Stück bei Bedarf'. Als Quelle dient hier ausschließlich der Arzt oder Apotheker"/>
          <comment
                   value="Die Freitextdosierung sollte nur angegeben werden, wenn aufgrund der Komplexität keine strukturierte Dosierung möglich ist, um widersprüchliche Anweisungen zu vermeiden."/>
          <requirements
                        value="Free text dosage instructions can be used for cases where the instructions are too complex to code.  The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated.  If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing.  Additional information about administration or preparation of the medication should be included as text."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.text"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="string"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <mustSupport value="true"/>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="v2"/>
            <map value="RXO-6; RXE-21"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".text"/>
          </mapping>
        </element>
        <element id="Dosage.additionalInstruction">
          <path value="Dosage.additionalInstruction"/>
          <short
                 value="Supplemental instruction or warnings to the patient - e.g. &quot;with meals&quot;, &quot;may cause drowsiness&quot;"/>
          <definition
                      value="Supplemental instructions to the patient on how to take the medication  (e.g. &quot;with meals&quot; or&quot;take half to one hour before food&quot;) or warnings for the patient about the medication (e.g. &quot;may cause drowsiness&quot; or &quot;avoid exposure of skin to direct sunlight or sunlamps&quot;)."/>
          <comment
                   value="Information about administration or preparation of the medication (e.g. &quot;infuse as rapidly as possibly via intraperitoneal port&quot; or &quot;immediately following drug x&quot;) should be populated in dosage.text."/>
          <requirements
                        value="Additional instruction is intended to be coded, but where no code exists, the element could include text.  For example, &quot;Swallow with plenty of water&quot; which might or might not be coded."/>
          <min value="0"/>
          <max value="*"/>
          <base>
            <path value="Dosage.additionalInstruction"/>
            <min value="0"/>
            <max value="*"/>
          </base>
          <type>
            <code value="CodeableConcept"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <binding>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
              <valueString value="AdditionalInstruction"/>
            </extension>
            <strength value="example"/>
            <description
                         value="A coded concept identifying additional instructions such as &quot;take with water&quot; or &quot;avoid operating heavy machinery&quot;."/>
            <valueSet
                      value="http://hl7.org/fhir/ValueSet/additional-instruction-codes|4.0.1"/>
          </binding>
          <mapping>
            <identity value="v2"/>
            <map value="RXO-7"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".text"/>
          </mapping>
        </element>
        <element id="Dosage.patientInstruction">
          <path value="Dosage.patientInstruction"/>
          <short value="Patient or consumer oriented instructions"/>
          <definition
                      value="Instructions in terms that are understood by the patient or consumer."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.patientInstruction"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="string"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="v2"/>
            <map value="RXO-7"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".text"/>
          </mapping>
        </element>
        <element id="Dosage.timing">
          <path value="Dosage.timing"/>
          <short value="Wann das Medikament verabreicht werden soll"/>
          <definition value="Wann das Medikament verabreicht werden soll."/>
          <comment
                   value="Um widersprüchliche Anweisungen zu vermeiden, ist entweder Dosage.timing oder Dosage.text zu befüllen. Falls eine strukturierte Dosierung als Text abgebildet werden soll ist dafür die GeneratedDosageInstructionsMeta Extension zu verwenden."/>
          <requirements
                        value="The timing schedule for giving the medication to the patient. This  data type allows many different expressions. For example: &quot;Every 8 hours&quot;; &quot;Three times a day&quot;; &quot;1/2 an hour before breakfast for 10 days from 23-Dec 2011:&quot;; &quot;15 Oct 2013, 17 Oct 2013 and 1 Nov 2013&quot;.  Sometimes, a rate can imply duration when expressed as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.timing"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="Timing"/>
            <profile
                     value="http://ig.fhir.de/igs/medication/StructureDefinition/TimingDE"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <mustSupport value="true"/>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="rim"/>
            <map value=".effectiveTime"/>
          </mapping>
        </element>
        <element id="Dosage.asNeeded[x]">
          <path value="Dosage.asNeeded[x]"/>
          <short value="Take &quot;as needed&quot; (for x)"/>
          <definition
                      value="Indicates whether the Medication is only taken when needed within a specific dosing schedule (Boolean option), or it indicates the precondition for taking the Medication (CodeableConcept)."/>
          <comment
                   value="Can express &quot;as needed&quot; without a reason by setting the Boolean = True.  In this case the CodeableConcept is not populated.  Or you can express &quot;as needed&quot; with a reason by including the CodeableConcept.  In this case the Boolean is assumed to be True.  If you set the Boolean to False, then the dose is given according to the schedule and is not &quot;prn&quot; or &quot;as needed&quot;."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.asNeeded[x]"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="boolean"/>
          </type>
          <type>
            <code value="CodeableConcept"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <binding>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
              <valueString value="MedicationAsNeededReason"/>
            </extension>
            <strength value="example"/>
            <description
                         value="A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose.  For example &quot;pain&quot;, &quot;30 minutes prior to sexual intercourse&quot;, &quot;on flare-up&quot; etc."/>
            <valueSet
                      value="http://hl7.org/fhir/ValueSet/medication-as-needed-reason|4.0.1"/>
          </binding>
          <mapping>
            <identity value="v2"/>
            <map value="TQ1-9"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map
                 value=".outboundRelationship[typeCode=PRCN].target[classCode=OBS, moodCode=EVN, code=&quot;as needed&quot;].value=boolean or codable concept"/>
          </mapping>
        </element>
        <element id="Dosage.site">
          <path value="Dosage.site"/>
          <short value="Body site to administer to"/>
          <definition value="Body site to administer to."/>
          <comment
                   value="If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension [bodySite](http://hl7.org/fhir/R4/extension-bodysite.html).  May be a summary code, or a reference to a very precise definition of the location, or both."/>
          <requirements
                        value="A coded specification of the anatomic site where the medication first enters the body."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.site"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="CodeableConcept"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <binding>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
              <valueString value="MedicationAdministrationSite"/>
            </extension>
            <strength value="example"/>
            <description
                         value="A coded concept describing the site location the medicine enters into or onto the body."/>
            <valueSet
                      value="http://hl7.org/fhir/ValueSet/approach-site-codes|4.0.1"/>
          </binding>
          <mapping>
            <identity value="v2"/>
            <map value="RXR-2"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".approachSiteCode"/>
          </mapping>
        </element>
        <element id="Dosage.route">
          <path value="Dosage.route"/>
          <short value="How drug should enter body"/>
          <definition value="How drug should enter body."/>
          <requirements
                        value="A code specifying the route or physiological path of administration of a therapeutic agent into or onto a patient's body."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.route"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="CodeableConcept"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <binding>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
              <valueString value="RouteOfAdministration"/>
            </extension>
            <strength value="example"/>
            <description
                         value="A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject."/>
            <valueSet value="http://hl7.org/fhir/ValueSet/route-codes|4.0.1"/>
          </binding>
          <mapping>
            <identity value="v2"/>
            <map value="RXR-1"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".routeCode"/>
          </mapping>
        </element>
        <element id="Dosage.method">
          <path value="Dosage.method"/>
          <short value="Technique for administering medication"/>
          <definition value="Technique for administering medication."/>
          <comment
                   value="Terminologies used often pre-coordinate this term with the route and or form of administration."/>
          <requirements
                        value="A coded value indicating the method by which the medication is introduced into or onto the body. Most commonly used for injections.  For examples, Slow Push; Deep IV."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.method"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="CodeableConcept"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <binding>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
              <valueString value="MedicationAdministrationMethod"/>
            </extension>
            <strength value="example"/>
            <description
                         value="A coded concept describing the technique by which the medicine is administered."/>
            <valueSet
                      value="http://hl7.org/fhir/ValueSet/administration-method-codes|4.0.1"/>
          </binding>
          <mapping>
            <identity value="v2"/>
            <map value="RXR-4"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".doseQuantity"/>
          </mapping>
        </element>
        <element id="Dosage.doseAndRate">
          <path value="Dosage.doseAndRate"/>
          <short value="Menge des verabreichten Medikaments"/>
          <definition value="Die verabreichte Menge des Medikaments."/>
          <min value="0"/>
          <max value="*"/>
          <base>
            <path value="Dosage.doseAndRate"/>
            <min value="0"/>
            <max value="*"/>
          </base>
          <type>
            <code value="Element"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <mustSupport value="true"/>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="v2"/>
            <map value="TQ1-2"/>
          </mapping>
        </element>
        <element id="Dosage.doseAndRate.id">
          <path value="Dosage.doseAndRate.id"/>
          <representation value="xmlAttr"/>
          <short value="Unique id for inter-element referencing"/>
          <definition
                      value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Element.id"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
              <valueUrl value="string"/>
            </extension>
            <code value="http://hl7.org/fhirpath/System.String"/>
          </type>
          <isModifier value="false"/>
          <isSummary value="false"/>
          <mapping>
            <identity value="rim"/>
            <map value="n/a"/>
          </mapping>
        </element>
        <element id="Dosage.doseAndRate.extension">
          <path value="Dosage.doseAndRate.extension"/>
          <slicing>
            <discriminator>
              <type value="value"/>
              <path value="url"/>
            </discriminator>
            <description value="Extensions are always sliced by (at least) url"/>
            <rules value="open"/>
          </slicing>
          <short value="Additional content defined by implementations"/>
          <definition
                      value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
          <comment
                   value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
          <alias value="extensions"/>
          <alias value="user content"/>
          <min value="0"/>
          <max value="*"/>
          <base>
            <path value="Element.extension"/>
            <min value="0"/>
            <max value="*"/>
          </base>
          <type>
            <code value="Extension"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <constraint>
            <key value="ext-1"/>
            <severity value="error"/>
            <human value="Must have either extensions or value[x], not both"/>
            <expression value="extension.exists() != value.exists()"/>
            <xpath
                   value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Extension"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="false"/>
          <mapping>
            <identity value="rim"/>
            <map value="n/a"/>
          </mapping>
        </element>
        <element id="Dosage.doseAndRate.type">
          <path value="Dosage.doseAndRate.type"/>
          <short value="The kind of dose or rate specified"/>
          <definition
                      value="The kind of dose or rate specified, for example, ordered or calculated."/>
          <requirements
                        value="If the type is not populated, assume to be &quot;ordered&quot;."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.doseAndRate.type"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="CodeableConcept"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <binding>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
              <valueString value="DoseAndRateType"/>
            </extension>
            <strength value="example"/>
            <description value="The kind of dose or rate specified."/>
            <valueSet value="http://hl7.org/fhir/ValueSet/dose-rate-type|4.0.1"/>
          </binding>
          <mapping>
            <identity value="v2"/>
            <map value="RXO-21; RXE-23"/>
          </mapping>
        </element>
        <element id="Dosage.doseAndRate.dose[x]">
          <path value="Dosage.doseAndRate.dose[x]"/>
          <slicing>
            <discriminator>
              <type value="type"/>
              <path value="$this"/>
            </discriminator>
            <ordered value="false"/>
            <rules value="open"/>
          </slicing>
          <short value="Amount of medication per dose"/>
          <definition value="Amount of medication per dose."/>
          <comment
                   value="Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours."/>
          <requirements
                        value="The amount of therapeutic or other substance given at one administration event."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.doseAndRate.dose[x]"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="Range"/>
          </type>
          <type>
            <code value="Quantity"/>
            <profile
                     value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="v2"/>
            <map value="RXO-2, RXE-3"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".doseQuantity"/>
          </mapping>
        </element>
        <element id="Dosage.doseAndRate.dose[x]:doseQuantity">
          <path value="Dosage.doseAndRate.dose[x]"/>
          <sliceName value="doseQuantity"/>
          <short value="Menge des Medikaments pro Dosis"/>
          <definition value="Menge des Medikaments pro Dosis."/>
          <comment
                   value="Beachten Sie, dass dies die Menge des angegebenen Medikaments angibt, nicht die Menge für die einzelnen Wirkstoffe. Jede Wirkstoffmenge kann in der Medication-Ressource kommuniziert werden. Zum Beispiel, wenn man angeben möchte, dass eine Tablette 375 mg enthält und die Dosis eine Tablette beträgt, kann man die Medication-Ressource verwenden, um zu dokumentieren, dass die Tablette aus 375 mg des Wirkstoffs XYZ besteht. Alternativ, wenn die Dosis 375 mg beträgt, muss man möglicherweise nur angeben, dass es sich um eine Tablette handelt. Bei einer Infusion wie Dopamin, bei der 400 mg Dopamin in 500 ml einer Infusionslösung gemischt werden, würde dies alles in der Medication-Ressource kommuniziert werden. Wenn die Verabreichung nicht als sofortig vorgesehen ist (Rate ist vorhanden oder Timing hat eine Dauer), kann dies angegeben werden, um die Gesamtmenge anzugeben, die über den im Zeitplan angegebenen Zeitraum verabreicht werden soll, z. B. 500 ml in der Dosis, wobei Timing verwendet wird, um anzugeben, dass dies über 4 Stunden erfolgen soll."/>
          <requirements
                        value="The amount of therapeutic or other substance given at one administration event."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.doseAndRate.dose[x]"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="Quantity"/>
            <profile
                     value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <mustSupport value="true"/>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <binding>
            <strength value="required"/>
            <valueSet
                      value="http://ig.fhir.de/igs/medication/ValueSet/DosageDoseQuantityDE"/>
          </binding>
          <mapping>
            <identity value="v2"/>
            <map value="RXO-2, RXE-3"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".doseQuantity"/>
          </mapping>
        </element>
        <element id="Dosage.doseAndRate.rate[x]">
          <path value="Dosage.doseAndRate.rate[x]"/>
          <short value="Amount of medication per unit of time"/>
          <definition value="Amount of medication per unit of time."/>
          <comment
                   value="It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate.

    It is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity.  The rateQuantity approach requires systems to have the capability to parse UCUM grammer where ml/hour is included rather than a specific ratio where the time is specified as the denominator.  Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour."/>
          <requirements
                        value="Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr.  May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours.   Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours.  Sometimes, a rate can imply duration when expressed as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.doseAndRate.rate[x]"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="Ratio"/>
          </type>
          <type>
            <code value="Range"/>
          </type>
          <type>
            <code value="Quantity"/>
            <profile
                     value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="v2"/>
            <map value="RXE22, RXE23, RXE-24"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".rateQuantity"/>
          </mapping>
        </element>
        <element id="Dosage.maxDosePerPeriod">
          <path value="Dosage.maxDosePerPeriod"/>
          <short value="Upper limit on medication per unit of time"/>
          <definition value="Upper limit on medication per unit of time."/>
          <comment
                   value="This is intended for use as an adjunct to the dosage when there is an upper cap.  For example &quot;2 tablets every 4 hours to a maximum of 8/day&quot;."/>
          <requirements
                        value="The maximum total quantity of a therapeutic substance that may be administered to a subject over the period of time.  For example, 1000mg in 24 hours."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.maxDosePerPeriod"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="Ratio"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="v2"/>
            <map value="RXO-23, RXE-19"/>
          </mapping>
          <mapping>
            <identity value="rim"/>
            <map value=".maxDoseQuantity"/>
          </mapping>
        </element>
        <element id="Dosage.maxDosePerAdministration">
          <path value="Dosage.maxDosePerAdministration"/>
          <short value="Upper limit on medication per administration"/>
          <definition value="Upper limit on medication per administration."/>
          <comment
                   value="This is intended for use as an adjunct to the dosage when there is an upper cap.  For example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum 2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration of 2 mg."/>
          <requirements
                        value="The maximum total quantity of a therapeutic substance that may be administered to a subject per administration."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.maxDosePerAdministration"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="Quantity"/>
            <profile
                     value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="rim"/>
            <map value="not supported"/>
          </mapping>
        </element>
        <element id="Dosage.maxDosePerLifetime">
          <path value="Dosage.maxDosePerLifetime"/>
          <short value="Upper limit on medication per lifetime of the patient"/>
          <definition
                      value="Upper limit on medication per lifetime of the patient."/>
          <requirements
                        value="The maximum total quantity of a therapeutic substance that may be administered per lifetime of the subject."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="Dosage.maxDosePerLifetime"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="Quantity"/>
            <profile
                     value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1"/>
          </type>
          <constraint>
            <key value="ele-1"/>
            <severity value="error"/>
            <human value="All FHIR elements must have a @value or children"/>
            <expression
                        value="hasValue() or (children().count() &gt; id.count())"/>
            <xpath value="@value|f:*|h:div"/>
            <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
          </constraint>
          <isModifier value="false"/>
          <isSummary value="true"/>
          <mapping>
            <identity value="rim"/>
            <map value="not supported"/>
          </mapping>
        </element>
      </snapshot>
      <differential>
        <element id="Dosage">
          <path value="Dosage"/>
          <constraint>
            <key value="DosageStructuredOrFreeTextWarning"/>
            <severity value="warning"/>
            <human
                   value="Die Dosierungsangabe darf entweder nur als Freitext oder nur als vollständige strukturierte Information erfolgen — eine Mischung ist nicht erlaubt."/>
            <expression
                        value="(%resource.ofType(MedicationRequest).dosageInstruction |
     ofType(MedicationDispense).dosageInstruction |
     ofType(MedicationStatement).dosage).all(
      (text.exists() and timing.empty() and doseAndRate.empty()) or
      (text.empty() and (timing.exists() or doseAndRate.exists()))
    )
    "/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
          <constraint>
            <key value="DosageStructuredRequiresBoth"/>
            <severity value="error"/>
            <human
                   value="Wenn eine strukturierte Dosierungsangabe erfolgt, müssen sowohl timing als auch doseAndRate angegeben werden."/>
            <expression
                        value="(%resource.ofType(MedicationRequest).dosageInstruction |
     ofType(MedicationDispense).dosageInstruction |
     ofType(MedicationStatement).dosage).all(
      (timing.exists() implies doseAndRate.exists()) and
      (doseAndRate.exists() implies timing.exists())
    )
    "/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
          <constraint>
            <key value="DosageDoseUnitSameCode"/>
            <severity value="error"/>
            <human
                   value="Die Dosiereinheit muss über alle Dosierungen gleich sein."/>
            <expression
                        value="(%resource.ofType(MedicationRequest).dosageInstruction | ofType(MedicationDispense).dosageInstruction | ofType(MedicationStatement).dosage).all(
    doseAndRate.exists() implies
      (
        %resource.dosageInstruction.doseAndRate.dose.ofType(Quantity).code |
        %resource.dosageInstruction.doseAndRate.dose.ofType(Range).low.code |
        %resource.dosageInstruction.doseAndRate.dose.ofType(Range).high.code
      ).distinct().count() = 1
    )"/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
          <constraint>
            <key value="DosageWarnungViererschemaInText"/>
            <severity value="warning"/>
            <human
                   value="Hinweis: In Dosage.text wurde ein Viererschema (z. B. 1-1-1-1) erkannt. Bitte prüfen, ob dies strukturiert abgebildet werden kann."/>
            <expression
                        value="text.exists() implies text.matches('.*\\d+\\s*[-–]\\s*\\d+\\s*[-–]\\s*\\d+\\s*[-–]\\d+.*').not()"/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
          <constraint>
            <key value="FreeTextSingleDosageOnlyWarning"/>
            <severity value="warning"/>
            <human
                   value="Wenn eine Dosierung als reiner Freitext angegeben ist, soll nur genau ein Dosage-Element existieren."/>
            <expression
                        value="(
      (%resource.ofType(MedicationRequest).dosageInstruction |
       %resource.ofType(MedicationDispense).dosageInstruction |
       %resource.ofType(MedicationStatement).dosage
      ).exists(text.exists() and timing.empty() and doseAndRate.empty())
    )
    implies
    (
      (%resource.ofType(MedicationRequest).dosageInstruction |
       %resource.ofType(MedicationDispense).dosageInstruction |
       %resource.ofType(MedicationStatement).dosage
      ).count() = 1
    )"/>
            <source
                    value="http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE"/>
          </constraint>
        </element>
        <element id="Dosage.text">
          <path value="Dosage.text"/>
          <short
                 value="Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Stück bei Bedarf'"/>
          <definition
                      value="Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Stück bei Bedarf'. Als Quelle dient hier ausschließlich der Arzt oder Apotheker"/>
          <comment
                   value="Die Freitextdosierung sollte nur angegeben werden, wenn aufgrund der Komplexität keine strukturierte Dosierung möglich ist, um widersprüchliche Anweisungen zu vermeiden."/>
          <mustSupport value="true"/>
        </element>
        <element id="Dosage.timing">
          <path value="Dosage.timing"/>
          <short value="Wann das Medikament verabreicht werden soll"/>
          <definition value="Wann das Medikament verabreicht werden soll."/>
          <comment
                   value="Um widersprüchliche Anweisungen zu vermeiden, ist entweder Dosage.timing oder Dosage.text zu befüllen. Falls eine strukturierte Dosierung als Text abgebildet werden soll ist dafür die GeneratedDosageInstructionsMeta Extension zu verwenden."/>
          <type>
            <code value="Timing"/>
            <profile
                     value="http://ig.fhir.de/igs/medication/StructureDefinition/TimingDE"/>
          </type>
          <mustSupport value="true"/>
        </element>
        <element id="Dosage.doseAndRate">
          <path value="Dosage.doseAndRate"/>
          <short value="Menge des verabreichten Medikaments"/>
          <definition value="Die verabreichte Menge des Medikaments."/>
          <mustSupport value="true"/>
        </element>
        <element id="Dosage.doseAndRate.dose[x]">
          <path value="Dosage.doseAndRate.dose[x]"/>
          <slicing>
            <discriminator>
              <type value="type"/>
              <path value="$this"/>
            </discriminator>
            <ordered value="false"/>
            <rules value="open"/>
          </slicing>
        </element>
        <element id="Dosage.doseAndRate.dose[x]:doseQuantity">
          <path value="Dosage.doseAndRate.dose[x]"/>
          <sliceName value="doseQuantity"/>
          <short value="Menge des Medikaments pro Dosis"/>
          <definition value="Menge des Medikaments pro Dosis."/>
          <comment
                   value="Beachten Sie, dass dies die Menge des angegebenen Medikaments angibt, nicht die Menge für die einzelnen Wirkstoffe. Jede Wirkstoffmenge kann in der Medication-Ressource kommuniziert werden. Zum Beispiel, wenn man angeben möchte, dass eine Tablette 375 mg enthält und die Dosis eine Tablette beträgt, kann man die Medication-Ressource verwenden, um zu dokumentieren, dass die Tablette aus 375 mg des Wirkstoffs XYZ besteht. Alternativ, wenn die Dosis 375 mg beträgt, muss man möglicherweise nur angeben, dass es sich um eine Tablette handelt. Bei einer Infusion wie Dopamin, bei der 400 mg Dopamin in 500 ml einer Infusionslösung gemischt werden, würde dies alles in der Medication-Ressource kommuniziert werden. Wenn die Verabreichung nicht als sofortig vorgesehen ist (Rate ist vorhanden oder Timing hat eine Dauer), kann dies angegeben werden, um die Gesamtmenge anzugeben, die über den im Zeitplan angegebenen Zeitraum verabreicht werden soll, z. B. 500 ml in der Dosis, wobei Timing verwendet wird, um anzugeben, dass dies über 4 Stunden erfolgen soll."/>
          <min value="0"/>
          <max value="1"/>
          <type>
            <code value="Quantity"/>
            <profile
                     value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/>
          </type>
          <mustSupport value="true"/>
          <binding>
            <strength value="required"/>
            <valueSet
                      value="http://ig.fhir.de/igs/medication/ValueSet/DosageDoseQuantityDE"/>
          </binding>
        </element>
      </differential>
    </StructureDefinition>