{
  "resourceType" : "ValueSet",
  "id" : "imm-pat-pk-measurement-vs",
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ValueSet imm-pat-pk-measurement-vs</b></p><a name=\"imm-pat-pk-measurement-vs\"> </a><a name=\"hcimm-pat-pk-measurement-vs\"> </a><p>This value set includes codes based on the following rules:</p><ul><li>Include these codes as defined in <a href=\"http://loinc.org\"><code>http://loinc.org</code></a><span title=\"Version is not explicitly stated. No matching Code System found\"> version Not Stated (use latest from terminology server)</span><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td><a href=\"https://loinc.org/77348-1/\">77348-1</a></td><td>Tacrolimus [Mass/volume] in Blood --trough</td></tr><tr><td><a href=\"https://loinc.org/53828-0/\">53828-0</a></td><td>cycloSPORINE [Mass/volume] in Blood --trough</td></tr><tr><td><a href=\"https://loinc.org/115766-8/\">115766-8</a></td><td>Sirolimus --trough [Mass/volume] of Blood</td></tr><tr><td><a href=\"https://loinc.org/77349-9/\">77349-9</a></td><td>Everolimus [Mass/volume] in Blood by LC/MS/MS --trough</td></tr><tr><td><a href=\"https://loinc.org/72667-9/\">72667-9</a></td><td>Mycophenolate [Mass/volume] in Serum or Plasma --trough</td></tr><tr><td><a href=\"https://loinc.org/32997-9/\">32997-9</a></td><td>cycloSPORINE [Mass/volume] in Blood --2 hours post dose</td></tr><tr><td><a href=\"https://loinc.org/92727-7/\">92727-7</a></td><td>Tacrolimus [AUC] in Blood</td></tr><tr><td><a href=\"https://loinc.org/99413-7/\">99413-7</a></td><td>cycloSPORINE [AUC] in Blood</td></tr><tr><td><a href=\"https://loinc.org/115789-0/\">115789-0</a></td><td>Mycophenolate [AUC] of Blood</td></tr></table></li><li>Include these codes as defined in <a href=\"CodeSystem-imm-pat-pk-type-cs.html\"><code>https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-pat-pk-type-cs</code></a><span title=\"Version is not explicitly stated, which means it is fixed to the version provided in this specification\"> version &#x1F4E6;0.1.0-ci-build</span><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td><a href=\"CodeSystem-imm-pat-pk-type-cs.html#imm-pat-pk-type-cs-auc\">auc</a></td><td style=\"color: #cccccc\">Pharmacokinetic AUC</td><td>Area under the concentration-time curve (pharmacokinetic exposure).</td></tr></table></li></ul></div>"
  },
  "url" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ValueSet/imm-pat-pk-measurement-vs",
  "version" : "0.1.0-ci-build",
  "name" : "ImmPatPKMeasurementVS",
  "title" : "Immunosuppressant PK Measurement ValueSet",
  "status" : "draft",
  "experimental" : true,
  "date" : "2026-09-28T06:51:47+00:00",
  "publisher" : "Protect Child",
  "contact" : [{
    "name" : "Protect Child",
    "telecom" : [{
      "system" : "url",
      "value" : "https://protect-child.eu/"
    }]
  }],
  "description" : "LOINC codes for immunosuppressant pharmacokinetic measurements — trough (C0), 2 h post-dose (C2) and AUC — one per drug. ImmPatPKTypeCS#auc is retained for sirolimus and everolimus, for which LOINC has no AUC code.",
  "compose" : {
    "include" : [{
      "system" : "http://loinc.org",
      "concept" : [{
        "code" : "77348-1",
        "display" : "Tacrolimus [Mass/volume] in Blood --trough"
      },
      {
        "code" : "53828-0",
        "display" : "cycloSPORINE [Mass/volume] in Blood --trough"
      },
      {
        "code" : "115766-8",
        "display" : "Sirolimus --trough [Mass/volume] of Blood"
      },
      {
        "code" : "77349-9",
        "display" : "Everolimus [Mass/volume] in Blood by LC/MS/MS --trough"
      },
      {
        "code" : "72667-9",
        "display" : "Mycophenolate [Mass/volume] in Serum or Plasma --trough"
      },
      {
        "code" : "32997-9",
        "display" : "cycloSPORINE [Mass/volume] in Blood --2 hours post dose"
      },
      {
        "code" : "92727-7",
        "display" : "Tacrolimus [AUC] in Blood"
      },
      {
        "code" : "99413-7",
        "display" : "cycloSPORINE [AUC] in Blood"
      },
      {
        "code" : "115789-0",
        "display" : "Mycophenolate [AUC] of Blood"
      }]
    },
    {
      "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-pat-pk-type-cs",
      "concept" : [{
        "code" : "auc"
      }]
    }]
  }
}