@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/ImmunologicalDataExample2> a fhir:Observation ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:Resource.id [ fhir:value "ImmunologicalDataExample2"] ;
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/immunological-data" ;
       fhir:index 0 ;
       fhir:link <https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/immunological-data>
     ]
  ] ;
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ] ;
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Observation ImmunologicalDataExample2</b></p><a name=\"ImmunologicalDataExample2\"> </a><a name=\"hcImmunologicalDataExample2\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-immunological-data.html\">Immunological Data</a></p></div><p><b>identifier</b>: <a href=\"NamingSystem-NsProtectChildId.html\" title=\"Single identifier namespace for PROTECT-CHILD record business identifiers (patient, donor, visit, transplant, and all per-visit clinical/lab/medication/specimen/event records). The resource type distinguishes the kind of record. Identifiers follow one convention: TOKEN-CENTRE-SEQUENCE, for example REC-1-0001 (patient, centre 1, sequence 1) or LBR-1-0006 (lab result); study-wide catalogue entries such as lab tests are not centre-qualified and use TOKEN-SEQUENCE, for example LBT-0001. Identifiers carry no clinical meaning.\">ProtectChildId</a>/IMD-1-0002</p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/immunological-data-panel-cs immunological-data-panel}\">Immunological data panel</span></p><p><b>subject</b>: <a href=\"Patient-ExamplePatientTransplant1.html\">Anonymous Patient Female, DoB Unknown ( https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/protect-child-id#ProtectChildId#REC-1-0001)</a></p><p><b>encounter</b>: <a href=\"Encounter-VisitClinicalEventExample1.html\">Encounter: identifier = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/protect-child-id#ProtectChildId#VIS-1-0003; status = finished; class = ambulatory (ActCode#AMB); type = Clinical Event visit; period = 2023-11-15 --&gt; 2023-11-15</a></p><p><b>effective</b>: 2023-11-15</p><p><b>performer</b>: <a href=\"Organization-PCCenter1LaPaz.html\">Organization La Paz University Hospital</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs ihc-if-c4d}\">IHC/IF C4d result</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs c4d-result}\">C4d result detail</span></p><p><b>value</b>: C4d positive in the portal microvasculature, diffuse portal capillary staining</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs if-result}\">Immunofluorescence result</span></p><p><b>value</b>: Diffuse portal microvascular C4d staining; no immune-complex deposition</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs post-tx-dsa-class}\">Post-transplant anti-HLA DSA class</span></p><p><b>value</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dsa-class-cs class-i}\">Class I</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs mfi-category}\">MFI category</span></p><p><b>value</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/mfi-category-cs SR}\">SR (strong, &gt;4k)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs antibody-type}\">Antibody type specification</span></p><p><b>value</b>: Anti-HLA class I donor-specific antibody against B*44:03</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs anca}\">ANCA result</span></p><p><b>value</b>: false</p></blockquote></div>"
  ] ;
  fhir:Observation.identifier [
     fhir:index 0 ;
     fhir:Identifier.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/protect-child-id" ] ;
     fhir:Identifier.value [ fhir:value "IMD-1-0002" ]
  ] ;
  fhir:Observation.status [ fhir:value "final"] ;
  fhir:Observation.category [
     fhir:index 0 ;
     fhir:CodeableConcept.coding [
       fhir:index 0 ;
       fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ] ;
       fhir:Coding.code [ fhir:value "laboratory" ]
     ]
  ] ;
  fhir:Observation.code [
     fhir:CodeableConcept.coding [
       fhir:index 0 ;
       fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/immunological-data-panel-cs" ] ;
       fhir:Coding.code [ fhir:value "immunological-data-panel" ] ;
       fhir:Coding.display [ fhir:value "Immunological data panel" ]
     ]
  ] ;
  fhir:Observation.subject [
     fhir:link <https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Patient/ExamplePatientTransplant1> ;
     fhir:Reference.reference [ fhir:value "Patient/ExamplePatientTransplant1" ]
  ] ;
  fhir:Observation.encounter [
     fhir:link <https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Encounter/VisitClinicalEventExample1> ;
     fhir:Reference.reference [ fhir:value "Encounter/VisitClinicalEventExample1" ]
  ] ;
  fhir:Observation.effectiveDateTime [ fhir:value "2023-11-15"^^xsd:date] ;
  fhir:Observation.performer [
     fhir:index 0 ;
     fhir:link <https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Organization/PCCenter1LaPaz> ;
     fhir:Reference.reference [ fhir:value "Organization/PCCenter1LaPaz" ]
  ] ;
  fhir:Observation.component [
     fhir:index 0 ;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs" ] ;
         fhir:Coding.code [ fhir:value "ihc-if-c4d" ] ;
         fhir:Coding.display [ fhir:value "IHC/IF C4d result" ]
       ]
     ] ;
     fhir:Observation.component.valueBoolean [ fhir:value "true"^^xsd:boolean ]
  ], [
     fhir:index 1 ;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs" ] ;
         fhir:Coding.code [ fhir:value "c4d-result" ] ;
         fhir:Coding.display [ fhir:value "C4d result detail" ]
       ]
     ] ;
     fhir:Observation.component.valueString [ fhir:value "C4d positive in the portal microvasculature, diffuse portal capillary staining" ]
  ], [
     fhir:index 2 ;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs" ] ;
         fhir:Coding.code [ fhir:value "if-result" ] ;
         fhir:Coding.display [ fhir:value "Immunofluorescence result" ]
       ]
     ] ;
     fhir:Observation.component.valueString [ fhir:value "Diffuse portal microvascular C4d staining; no immune-complex deposition" ]
  ], [
     fhir:index 3 ;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs" ] ;
         fhir:Coding.code [ fhir:value "post-tx-dsa-class" ] ;
         fhir:Coding.display [ fhir:value "Post-transplant anti-HLA DSA class" ]
       ]
     ] ;
     fhir:Observation.component.valueCodeableConcept [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dsa-class-cs" ] ;
         fhir:Coding.code [ fhir:value "class-i" ] ;
         fhir:Coding.display [ fhir:value "Class I" ]
       ]
     ]
  ], [
     fhir:index 4 ;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs" ] ;
         fhir:Coding.code [ fhir:value "mfi-category" ] ;
         fhir:Coding.display [ fhir:value "MFI category" ]
       ]
     ] ;
     fhir:Observation.component.valueCodeableConcept [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/mfi-category-cs" ] ;
         fhir:Coding.code [ fhir:value "SR" ] ;
         fhir:Coding.display [ fhir:value "SR (strong, >4k)" ]
       ]
     ]
  ], [
     fhir:index 5 ;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs" ] ;
         fhir:Coding.code [ fhir:value "antibody-type" ] ;
         fhir:Coding.display [ fhir:value "Antibody type specification" ]
       ]
     ] ;
     fhir:Observation.component.valueString [ fhir:value "Anti-HLA class I donor-specific antibody against B*44:03" ]
  ], [
     fhir:index 6 ;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0 ;
         fhir:Coding.system [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs" ] ;
         fhir:Coding.code [ fhir:value "anca" ] ;
         fhir:Coding.display [ fhir:value "ANCA result" ]
       ]
     ] ;
     fhir:Observation.component.valueBoolean [ fhir:value "false"^^xsd:boolean ]
  ] .

# - ontology header ------------------------------------------------------------

<https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/ImmunologicalDataExample2.ttl> a owl:Ontology ;
  owl:imports fhir:fhir.ttl .

# -------------------------------------------------------------------------------------