{
  "resourceType" : "Observation",
  "id" : "ImmunologicalDataExample2",
  "meta" : {
    "profile" : ["https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/immunological-data"]
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Observation ImmunologicalDataExample2</b></p><a name=\"ImmunologicalDataExample2\"> </a><a name=\"hcImmunologicalDataExample2\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-immunological-data.html\">Immunological Data</a></p></div><p><b>identifier</b>: <a href=\"NamingSystem-NsProtectChildId.html\" title=\"Single identifier namespace for PROTECT-CHILD record business identifiers (patient, donor, visit, transplant, and all per-visit clinical/lab/medication/specimen/event records). The resource type distinguishes the kind of record. Identifiers follow one convention: TOKEN-CENTRE-SEQUENCE, for example REC-1-0001 (patient, centre 1, sequence 1) or LBR-1-0006 (lab result); study-wide catalogue entries such as lab tests are not centre-qualified and use TOKEN-SEQUENCE, for example LBT-0001. Identifiers carry no clinical meaning.\">ProtectChildId</a>/IMD-1-0002</p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/immunological-data-panel-cs immunological-data-panel}\">Immunological data panel</span></p><p><b>subject</b>: <a href=\"Patient-ExamplePatientTransplant1.html\">Anonymous Patient Female, DoB Unknown ( https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/protect-child-id#ProtectChildId#REC-1-0001)</a></p><p><b>encounter</b>: <a href=\"Encounter-VisitClinicalEventExample1.html\">Encounter: identifier = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/protect-child-id#ProtectChildId#VIS-1-0003; status = finished; class = ambulatory (ActCode#AMB); type = Clinical Event visit; period = 2023-11-15 --&gt; 2023-11-15</a></p><p><b>effective</b>: 2023-11-15</p><p><b>performer</b>: <a href=\"Organization-PCCenter1LaPaz.html\">Organization La Paz University Hospital</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs ihc-if-c4d}\">IHC/IF C4d result</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs c4d-result}\">C4d result detail</span></p><p><b>value</b>: C4d positive in the portal microvasculature, diffuse portal capillary staining</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs if-result}\">Immunofluorescence result</span></p><p><b>value</b>: Diffuse portal microvascular C4d staining; no immune-complex deposition</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs post-tx-dsa-class}\">Post-transplant anti-HLA DSA class</span></p><p><b>value</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dsa-class-cs class-i}\">Class I</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs mfi-category}\">MFI category</span></p><p><b>value</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/mfi-category-cs SR}\">SR (strong, &gt;4k)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs antibody-type}\">Antibody type specification</span></p><p><b>value</b>: Anti-HLA class I donor-specific antibody against B*44:03</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs anca}\">ANCA result</span></p><p><b>value</b>: false</p></blockquote></div>"
  },
  "identifier" : [{
    "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/protect-child-id",
    "value" : "IMD-1-0002"
  }],
  "status" : "final",
  "category" : [{
    "coding" : [{
      "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
      "code" : "laboratory"
    }]
  }],
  "code" : {
    "coding" : [{
      "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/immunological-data-panel-cs",
      "code" : "immunological-data-panel",
      "display" : "Immunological data panel"
    }]
  },
  "subject" : {
    "reference" : "Patient/ExamplePatientTransplant1"
  },
  "encounter" : {
    "reference" : "Encounter/VisitClinicalEventExample1"
  },
  "effectiveDateTime" : "2023-11-15",
  "performer" : [{
    "reference" : "Organization/PCCenter1LaPaz"
  }],
  "component" : [{
    "code" : {
      "coding" : [{
        "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
        "code" : "ihc-if-c4d",
        "display" : "IHC/IF C4d result"
      }]
    },
    "valueBoolean" : true
  },
  {
    "code" : {
      "coding" : [{
        "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
        "code" : "c4d-result",
        "display" : "C4d result detail"
      }]
    },
    "valueString" : "C4d positive in the portal microvasculature, diffuse portal capillary staining"
  },
  {
    "code" : {
      "coding" : [{
        "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
        "code" : "if-result",
        "display" : "Immunofluorescence result"
      }]
    },
    "valueString" : "Diffuse portal microvascular C4d staining; no immune-complex deposition"
  },
  {
    "code" : {
      "coding" : [{
        "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
        "code" : "post-tx-dsa-class",
        "display" : "Post-transplant anti-HLA DSA class"
      }]
    },
    "valueCodeableConcept" : {
      "coding" : [{
        "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dsa-class-cs",
        "code" : "class-i",
        "display" : "Class I"
      }]
    }
  },
  {
    "code" : {
      "coding" : [{
        "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
        "code" : "mfi-category",
        "display" : "MFI category"
      }]
    },
    "valueCodeableConcept" : {
      "coding" : [{
        "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/mfi-category-cs",
        "code" : "SR",
        "display" : "SR (strong, >4k)"
      }]
    }
  },
  {
    "code" : {
      "coding" : [{
        "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
        "code" : "antibody-type",
        "display" : "Antibody type specification"
      }]
    },
    "valueString" : "Anti-HLA class I donor-specific antibody against B*44:03"
  },
  {
    "code" : {
      "coding" : [{
        "system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
        "code" : "anca",
        "display" : "ANCA result"
      }]
    },
    "valueBoolean" : false
  }]
}