Code | Display | Comments |
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1.1 | RT to a vol exposing the thyroid gland | |
1.2 | TBI | |
1.3 | MIBG therapy (I-131 MIBG therapy) | |
2.1 | RT >= 10 Gy to a vol exposing the breasts | |
2.2 | OR upper abdominal field radiation that can extend above the diaphragm likely exposing breast tissue at a young age | |
3.1 | RT >= 35 Gy to a vol exposing the heart | |
3.2 | Anthracyclines (doxorubicin isotoxic equivalents)>= 250 mg/m2 | |
3.3 | RT >= 15 Gy to a vol exposing the heart AND Anthracyclines (doxorubicin isotoxic equivalents)>= 100 mg/m2 | |
4.1 | Alkylating agents | |
4.2 | RT to a vol exposing the testes | |
5.1 | RT between 15 and 35 Gy to a vol exposing the heart | RT >=12 Gy to a vol exposing the testicles | - display changed from left to right
- definition changed from left to right
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6.1 | RT to a vol exposing the testes or pelvis | | |
6.3 | Surgery to the spinal cord, sympathetic nerves or pelvis | |
6.4 | Hypogonadal | |
7.2 | RT to a vol exposing the ovaries | |
8.1 | RT >= 30 Gy to a vol exposing the head or the brain | |
8.2 | Cisplatin (with or without carboplatin > 1500 mg/m2) | |
9.1 | RT to a vol exposing the pancreas | |
10.2 | HSCT | |
11.1 | RT to a volume exposing the hypothalamus or pituatary gland | |
11.3 | Hypothalamic or pituitary tumour | |
11.4 | Neurosurgery of the hypothalamus or pituitary gland | |
12.1 | RT to a vol exposing the kidneys, heart and associated large vessels | |
12.3 | Nephrectomy | |
12.4 | Ifosfamide | |
12.5 | Platinium based chemotherapy | |
12.6 | Nitrosureas | |
12.7 | Immunosuppressives treatment and prolonged steroids as anticancer treatment (at least 4 weeks, continuously) | |
13.1 | Cranial and/or spinal RT | |
13.3 | Methotrexate | |
13.4 | Gonadal failure | |
13.5 | Growth hormone deficiency | |
13.6 | Prolonged (at least 4 weeks, continuously) corticosteroids as anti-cancer treatment | |
14.3 | High dose RT | |
15.1 | Radiotherapy to a vol exposing the HP region >= 30 Gy | |
15.2 | Surgery near or within the HP region | |
15.3 | CNS tumours near or within the HP region | |
16.1 | Radiotherapy to a vol exposing the HP region< 30 Gy | |
16.2 | Hydrocephalus or cerebrospinal fluid shunt (Risk factor for GHD) | Hydrocephalus or cerebrospinal fluid shunt(Risk factor for GHD) | - display changed from left to right
- definition changed from left to right
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17.1 | Radiotherapy to a vol exposing the HP region | |
17.3 | Surgery near or within the HP region | | |
18.1 | Radiotherapy to a vol exposing the HP region | | |
18.3 | Surgery near or within the HP region | | |
19.1 | RT to a vol exposing the thyroid gland | | |
19.3 | Radioiodine therapy (I-131 ablation therapy) | |
19.5 | Allogenic HSCT | |
19.6 | Total thyroidectomy | |
20.1 | RT to a vol exposing the head, brain or neck | |
21.1 | History of a central nervous system tumor | |
21.2 | RT to a vol exposing the brain ANY DOSE | RT to a vol exposing the brain ANY DOSE | - display changed from left to right
- definition changed from left to right
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21.4 | Brain surgery | |
21.5 | High dose cytarabine IV (intravenous) | |
21.6 | High dose MTX IV | |
21.7 | Any Chemotherapy IT (intrathecal) | |
22.1 | Vinca-Alkaloids | |
22.2 | Cisplatin or carboplatin | |
23.1 | RT to a vol exposing the lens | |
24.1 | RT to a vol exposing the eye and orbit | |
24.3 | Radioiodine therapy (I-131 ablation therapy) | | |
25.1 | RT to a vol exposing the craniofacial area, especially after high doses and at a young age | |
25.3 | Surgery to the face, especially at a young age | |
26.1 | Surgery of the spine | |
26.2 | Surgery of the chest (Does not include CVC pose) | |
26.3 | RT to a vol exposing the spine | |
26.4 | Spinal or paraspinal malignancies | |
27.1 | Cyclophosphamide | |
27.3 | RT to a vol exposing the bladder | |
27.5 | Cystectomy | |
27.6 | Hysterectomy | |
27.7 | Pelvic surgery | |
27.8 | Spinal cord surgery | |
28.1 | RT to a vol exposing the uterus only female | |
29.1 | RT to a vol exposing the oral cavity or salivary glands | |
29.4 | Chemotherapy | |
30.1 | RT to a vol exposing the gastro-intestinal tract | RT to a vol exposing the gastro-intestinal tract | - display changed from left to right
- definition changed from left to right
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30.3 | Oesophageal surgery | |
30.4 | Abdominal surgery | |
30.5 | With a history of chronic GVHD | |
31.1 | Anthracyclines (doxorubicin isotoxic equivalents) <100 mg/m2 | |
32.1 | RT to a vol exposing the lungs | |
32.3 | Bleomycin | |
32.4 | Busulfan | |
32.5 | BCNU Carmustine | BCNU Carmustine | - display changed from left to right
- definition changed from left to right
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32.6 | CCNU Lomustine | CCNU Lomustine | - display changed from left to right
- definition changed from left to right
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32.7 | Thoracic surgery | |
33.1 | Cisplatin Any dose | |
33.3 | Carboplatin Any dose | |
34.1 | RT to a volume exposing the liver | |
34.3 | HSCT (irrespective of GVHD) | |
34.5 | Mercaptopurine Thioguanine | |
34.6 | Dactinomycin | |
34.8 | Chronic viral hepatitis | |
34.9 | Sinusoidal obstruction syndrome | |
34.10 | Chronic GVHD | |
34.11 | Liver surgery | |
35.2 | Multiple red blood cell transfusions | |
36.1 | Splenectomy | |
36.2 | RT >= 10 Gy to a vol exposing the spleen | |
36.4 | Autologus HSCT conditioned with TBI | |
37.1 | Hereditary cancer sd | |
38.1 | Any RT including TBI | Any RT including TBI (predominantly in the RT field) | - display changed from left to right
- definition changed from left to right
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39.1 | RT to a vol exposing the colon and rectum | |
40.1 | RT to a vol exposing the oral cavity | |
41.2 | Anthracyclines and/or Mitoxantrone | |
41.3 | Epipodophyllotoxins or autologous | |
41.4 | Autologous haematopoietic stem cell transplant | |
42.1 | Ciclofosfamide, Ifosfamide (particularly if they have a history of severe hemorrhagic cystitis) | |
42.2 | RT to a vol exposing the bladder | | |
44.1 | RT to a vol exposing the lungs | | |
45.1 | RT to a vol exposing the head or brain | |
46.2 | Anthracyclines (doxorubicin isotoxic equivalents) between 100 and 250 mg/m2 | |
47.1 | RT to a vol exposing the kidney or urinary tract | |
4.3 | | Including TBI | |
13.7 | | HSCT, especially with an history of GVHD | |
17.5 | | hydrocephalus or cerebrospinal fluid shunt | |
33.2 | | Ifosfamide Any dose | |
35.1 | | HSCT (irrespective of GVHD) | |
36.3 | | Allogenic HSCT (with or without TBI) | |
38.2 | | HSCT Especially with a history of skin GvHD | |
46.1 | | RT between 15 and 35 Gy to a vol exposing the heart | |