PanCareSurPass Project HL7 FHIR Implementation Guide
1.0.0 - release 150

PanCareSurPass Project HL7 FHIR Implementation Guide, published by PanCareSurPass Project. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/pcsp/ and changes regularly. See the Directory of published versions

## Logical Model: FrontLineTreatment - JSON Profile

Active as of 2026-01-16

JSON representation of the FrontLineTreatment logical model.

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    {
      "resourceType" : "StructureDefinition",
      "id" : "FrontLineTreatment",
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: StructureDefinition FrontLineTreatment</b></p><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Minimum and Maximum # of times the element can appear in the instance\">Card.</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px; width: 100px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Additional information about the element\">Description &amp; Constraints</a><span style=\"float: right\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64, \" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment\" title=\"Front Line Treatment. The first treatment given for a disease. It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation. When used by itself, first-line therapy is the one accepted as the best treatment. If it does not cure the disease or it causes severe side effects, other treatment may be added or used instead. Also called induction therapy, primary therapy, and primary treatment.\">FrontLineTreatment</a><a name=\"FrontLineTreatment\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">*</span></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://build.fhir.org/types.html#Base\">Base</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Front Line Treatment</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.followedProtocol\" title=\"Followed Protocol\">followedProtocol</a><a name=\"FrontLineTreatment.followedProtocol\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Followed Protocol<br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.followedProtocol.type\" title=\"2 =&gt; Trial/protocol\n2 =&gt; Personalized\n3 =&gt; Guidelines\n-9922 =&gt; NK\">type</a><a name=\"FrontLineTreatment.followedProtocol.type\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Protocole type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.followedProtocol.name\" title=\"Protocole name\">name</a><a name=\"FrontLineTreatment.followedProtocol.name\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Protocole name</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.followedProtocol.description\" title=\"If a specific trial/protocol was used, please specify.  \nIn case of relapse/progression during front line treatment,please report both the name of the front line as well of the salvage treatment\nIf personalized, please specify.  \">description</a><a name=\"FrontLineTreatment.followedProtocol.description\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Protocol name or description</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.followedProtocol.arm\" title=\"If the trial was randomized, please define randomization arm\">arm</a><a name=\"FrontLineTreatment.followedProtocol.arm\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Group/Arm/Randomization</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.dateEOT\" title=\"It might be the date of first elective end of treatment, or that of the second (or further) end of treatment after the first one. If the date is unkown or partially missed insert the year at the best of your knowledge.\">dateEOT</a><a name=\"FrontLineTreatment.dateEOT\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#dateTime\">dateTime</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Date of end of treatment</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.isChemotherapy\" title=\"Chemotherapy ?\">isChemotherapy</a><a name=\"FrontLineTreatment.isChemotherapy\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Chemotherapy ?</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.isStemCellTransplantation\" title=\"Stem Cell transplantation ?\">isStemCellTransplantation</a><a name=\"FrontLineTreatment.isStemCellTransplantation\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Stem Cell transplantation ?</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.isRadiotherapy\" title=\"Radiotherapy ?\">isRadiotherapy</a><a name=\"FrontLineTreatment.isRadiotherapy\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Radiotherapy ?</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.isMajorSurgery\" title=\"Major Surgery ?\">isMajorSurgery</a><a name=\"FrontLineTreatment.isMajorSurgery\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Major Surgery ?</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.notForRelapse\" title=\"Details not provided for relapses after EOT\">notForRelapse</a><a name=\"FrontLineTreatment.notForRelapse\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Details not provided for relapses after EOT</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.notForRelapse.completeRemission\" title=\"Complete remission\">completeRemission</a><a name=\"FrontLineTreatment.notForRelapse.completeRemission\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Complete remission</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.notForRelapse.completeRemission.status\" title=\"Complete remission (Yes/No)\">status</a><a name=\"FrontLineTreatment.notForRelapse.completeRemission.status\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#dateTime\">dateTime</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Complete remission (Yes/No)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.notForRelapse.completeRemission.description\" title=\"Textual description in case of no remission\">description</a><a name=\"FrontLineTreatment.notForRelapse.completeRemission.description\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Textual description in case of no remission</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.notForRelapse.isProgressionRelapseDuringFLT\" title=\"Progression/relapse during frontline treatment ?\">isProgressionRelapseDuringFLT</a><a name=\"FrontLineTreatment.notForRelapse.isProgressionRelapseDuringFLT\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Progression/relapse during frontline treatment ?</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-FrontLineTreatment-definitions.html#FrontLineTreatment.notForRelapse.isProgressionRelapseAfterFLT\" title=\"Progression/relapse after first elective end of treatment ?\">isProgressionRelapseAfterFLT</a><a name=\"FrontLineTreatment.notForRelapse.isProgressionRelapseAfterFLT\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Progression/relapse after first elective end of treatment ?</td></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64, \" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
      },
      "url" : "http://hl7.eu/fhir/ig/pcsp/StructureDefinition/FrontLineTreatment",
      "version" : "1.0.0",
      "name" : "FrontLineTreatment",
      "title" : "Front Line Treatment",
      "status" : "active",
      "date" : "2026-01-16T12:01:48+00:00",
      "publisher" : "PanCareSurPass Project",
      "contact" : [
        {
          "name" : "PanCareSurPass Project",
          "telecom" : [
            {
              "system" : "url",
              "value" : "https://www.pancaresurpass.eu/"
            }
          ]
        },
        {
          "name" : "PanCareSurPass Project",
          "telecom" : [
            {
              "system" : "url",
              "value" : "https://www.pancaresurpass.eu/"
            }
          ]
        }
      ],
      "description" : "Front Line Treatment. The first treatment given for a disease. It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation. When used by itself, first-line therapy is the one accepted as the best treatment. If it does not cure the disease or it causes severe side effects, other treatment may be added or used instead. Also called induction therapy, primary therapy, and primary treatment.",
      "jurisdiction" : [
        {
          "coding" : [
            {
              "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
              "code" : "150",
              "display" : "Europe"
            }
          ]
        }
      ],
      "fhirVersion" : "4.0.1",
      "mapping" : [
        {
          "identity" : "fhir",
          "uri" : "hl7.org/fhir/r4",
          "name" : "FrontLineTreatment model to PCSP HL7 FHIR R4 Profiles"
        }
      ],
      "kind" : "logical",
      "abstract" : false,
      "type" : "http://hl7.eu/fhir/ig/pcsp/StructureDefinition/FrontLineTreatment",
      "baseDefinition" : "http://hl7.org/fhir/StructureDefinition/Base",
      "derivation" : "specialization",
      "snapshot" : {
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
            "valueString" : "4.0.1"
          }
        ],
        "element" : [
          {
            "id" : "FrontLineTreatment",
            "path" : "FrontLineTreatment",
            "short" : "Front Line Treatment",
            "definition" : "Front Line Treatment. The first treatment given for a disease. It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation. When used by itself, first-line therapy is the one accepted as the best treatment. If it does not cure the disease or it causes severe side effects, other treatment may be added or used instead. Also called induction therapy, primary therapy, and primary treatment.",
            "min" : 0,
            "max" : "*",
            "base" : {
              "path" : "Base",
              "min" : 0,
              "max" : "*"
            },
            "isModifier" : false,
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-flt-eu-pcsp')"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol",
            "path" : "FrontLineTreatment.followedProtocol",
            "short" : "Followed Protocol",
            "definition" : "Followed Protocol",
            "min" : 0,
            "max" : "*",
            "base" : {
              "path" : "FrontLineTreatment.followedProtocol",
              "min" : 0,
              "max" : "*"
            },
            "type" : [
              {
                "code" : "BackboneElement"
              }
            ],
            "constraint" : [
              {
                "key" : "ele-1",
                "severity" : "error",
                "human" : "All FHIR elements must have a @value or children",
                "expression" : "hasValue() or (children().count() > id.count())",
                "xpath" : "@value|f:*|h:div",
                "source" : "http://hl7.org/fhir/StructureDefinition/Element"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".instantiatesCanonical"
              },
              {
                "identity" : "fhir",
                "map" : "PlanDefinition.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/PlanDefinition-flt-eu-pcsp')"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.id",
            "path" : "FrontLineTreatment.followedProtocol.id",
            "representation" : [
              "xmlAttr"
            ],
            "short" : "Unique id for inter-element referencing",
            "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "Element.id",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                    "valueUrl" : "string"
                  }
                ],
                "code" : "http://hl7.org/fhirpath/System.String"
              }
            ],
            "isModifier" : false,
            "isSummary" : false,
            "mapping" : [
              {
                "identity" : "rim",
                "map" : "n/a"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.extension",
            "path" : "FrontLineTreatment.followedProtocol.extension",
            "slicing" : {
              "discriminator" : [
                {
                  "type" : "value",
                  "path" : "url"
                }
              ],
              "description" : "Extensions are always sliced by (at least) url",
              "rules" : "open"
            },
            "short" : "Additional content defined by implementations",
            "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
            "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
            "alias" : [
              "extensions",
              "user content"
            ],
            "min" : 0,
            "max" : "*",
            "base" : {
              "path" : "Element.extension",
              "min" : 0,
              "max" : "*"
            },
            "type" : [
              {
                "code" : "Extension"
              }
            ],
            "constraint" : [
              {
                "key" : "ele-1",
                "severity" : "error",
                "human" : "All FHIR elements must have a @value or children",
                "expression" : "hasValue() or (children().count() > id.count())",
                "xpath" : "@value|f:*|h:div",
                "source" : "http://hl7.org/fhir/StructureDefinition/Element"
              },
              {
                "key" : "ext-1",
                "severity" : "error",
                "human" : "Must have either extensions or value[x], not both",
                "expression" : "extension.exists() != value.exists()",
                "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
                "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
              }
            ],
            "isModifier" : false,
            "isSummary" : false,
            "mapping" : [
              {
                "identity" : "rim",
                "map" : "n/a"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.modifierExtension",
            "path" : "FrontLineTreatment.followedProtocol.modifierExtension",
            "short" : "Extensions that cannot be ignored even if unrecognized",
            "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
            "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
            "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
            "alias" : [
              "extensions",
              "user content",
              "modifiers"
            ],
            "min" : 0,
            "max" : "*",
            "base" : {
              "path" : "BackboneElement.modifierExtension",
              "min" : 0,
              "max" : "*"
            },
            "type" : [
              {
                "code" : "Extension"
              }
            ],
            "constraint" : [
              {
                "key" : "ele-1",
                "severity" : "error",
                "human" : "All FHIR elements must have a @value or children",
                "expression" : "hasValue() or (children().count() > id.count())",
                "xpath" : "@value|f:*|h:div",
                "source" : "http://hl7.org/fhir/StructureDefinition/Element"
              },
              {
                "key" : "ext-1",
                "severity" : "error",
                "human" : "Must have either extensions or value[x], not both",
                "expression" : "extension.exists() != value.exists()",
                "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
                "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
              }
            ],
            "isModifier" : true,
            "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
            "isSummary" : true,
            "mapping" : [
              {
                "identity" : "rim",
                "map" : "N/A"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.type",
            "path" : "FrontLineTreatment.followedProtocol.type",
            "short" : "Protocole type",
            "definition" : "2 => Trial/protocol\n2 => Personalized\n3 => Guidelines\n-9922 => NK",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.followedProtocol.type",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".type"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.name",
            "path" : "FrontLineTreatment.followedProtocol.name",
            "short" : "Protocole name",
            "definition" : "Protocole name",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.followedProtocol.name",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "string"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".title"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.description",
            "path" : "FrontLineTreatment.followedProtocol.description",
            "short" : "Protocol name or description",
            "definition" : "If a specific trial/protocol was used, please specify.  \nIn case of relapse/progression during front line treatment,please report both the name of the front line as well of the salvage treatment\nIf personalized, please specify.",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.followedProtocol.description",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "string"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".description"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.arm",
            "path" : "FrontLineTreatment.followedProtocol.arm",
            "short" : "Group/Arm/Randomization",
            "definition" : "If the trial was randomized, please define randomization arm",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.followedProtocol.arm",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "string"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/procedure-fltArm').valueString"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.dateEOT",
            "path" : "FrontLineTreatment.dateEOT",
            "short" : "Date of end of treatment",
            "definition" : "It might be the date of first elective end of treatment, or that of the second (or further) end of treatment after the first one. If the date is unkown or partially missed insert the year at the best of your knowledge.",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.dateEOT",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "dateTime"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.performedPeriod.end"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.isChemotherapy",
            "path" : "FrontLineTreatment.isChemotherapy",
            "short" : "Chemotherapy ?",
            "definition" : "Chemotherapy ?",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.isChemotherapy",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "MedicationAdministration.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/MedicationAdministration-eu-pcsp').exists()"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.isStemCellTransplantation",
            "path" : "FrontLineTreatment.isStemCellTransplantation",
            "short" : "Stem Cell transplantation ?",
            "definition" : "Stem Cell transplantation ?",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.isStemCellTransplantation",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-eu-pcsp').exists()"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.isRadiotherapy",
            "path" : "FrontLineTreatment.isRadiotherapy",
            "short" : "Radiotherapy ?",
            "definition" : "Radiotherapy ?",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.isRadiotherapy",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-radiotheraphy-eu-pcsp').exists()"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.isMajorSurgery",
            "path" : "FrontLineTreatment.isMajorSurgery",
            "short" : "Major Surgery ?",
            "definition" : "Major Surgery ?",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.isMajorSurgery",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-surgery-eu-pcsp').exists().not() [No Case, implicit]"
              },
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-surgery-eu-pcsp')..where(code = 'no-known-procedures').exists() [No Case, explicit]"
              },
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-surgery-eu-pcsp').where(code != 'no-known-procedures' or code != 'no-procedure-info').exists() [Yes Case]"
              },
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-surgery-eu-pcsp').where(code = 'no-procedure-info').exists() [Unk case]"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse",
            "path" : "FrontLineTreatment.notForRelapse",
            "short" : "Details not provided for relapses after EOT",
            "definition" : "Details not provided for relapses after EOT",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.notForRelapse",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "BackboneElement"
              }
            ],
            "constraint" : [
              {
                "key" : "ele-1",
                "severity" : "error",
                "human" : "All FHIR elements must have a @value or children",
                "expression" : "hasValue() or (children().count() > id.count())",
                "xpath" : "@value|f:*|h:div",
                "source" : "http://hl7.org/fhir/StructureDefinition/Element"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.id",
            "path" : "FrontLineTreatment.notForRelapse.id",
            "representation" : [
              "xmlAttr"
            ],
            "short" : "Unique id for inter-element referencing",
            "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "Element.id",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                    "valueUrl" : "string"
                  }
                ],
                "code" : "http://hl7.org/fhirpath/System.String"
              }
            ],
            "isModifier" : false,
            "isSummary" : false,
            "mapping" : [
              {
                "identity" : "rim",
                "map" : "n/a"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.extension",
            "path" : "FrontLineTreatment.notForRelapse.extension",
            "slicing" : {
              "discriminator" : [
                {
                  "type" : "value",
                  "path" : "url"
                }
              ],
              "description" : "Extensions are always sliced by (at least) url",
              "rules" : "open"
            },
            "short" : "Additional content defined by implementations",
            "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
            "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
            "alias" : [
              "extensions",
              "user content"
            ],
            "min" : 0,
            "max" : "*",
            "base" : {
              "path" : "Element.extension",
              "min" : 0,
              "max" : "*"
            },
            "type" : [
              {
                "code" : "Extension"
              }
            ],
            "constraint" : [
              {
                "key" : "ele-1",
                "severity" : "error",
                "human" : "All FHIR elements must have a @value or children",
                "expression" : "hasValue() or (children().count() > id.count())",
                "xpath" : "@value|f:*|h:div",
                "source" : "http://hl7.org/fhir/StructureDefinition/Element"
              },
              {
                "key" : "ext-1",
                "severity" : "error",
                "human" : "Must have either extensions or value[x], not both",
                "expression" : "extension.exists() != value.exists()",
                "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
                "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
              }
            ],
            "isModifier" : false,
            "isSummary" : false,
            "mapping" : [
              {
                "identity" : "rim",
                "map" : "n/a"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.modifierExtension",
            "path" : "FrontLineTreatment.notForRelapse.modifierExtension",
            "short" : "Extensions that cannot be ignored even if unrecognized",
            "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
            "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
            "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
            "alias" : [
              "extensions",
              "user content",
              "modifiers"
            ],
            "min" : 0,
            "max" : "*",
            "base" : {
              "path" : "BackboneElement.modifierExtension",
              "min" : 0,
              "max" : "*"
            },
            "type" : [
              {
                "code" : "Extension"
              }
            ],
            "constraint" : [
              {
                "key" : "ele-1",
                "severity" : "error",
                "human" : "All FHIR elements must have a @value or children",
                "expression" : "hasValue() or (children().count() > id.count())",
                "xpath" : "@value|f:*|h:div",
                "source" : "http://hl7.org/fhir/StructureDefinition/Element"
              },
              {
                "key" : "ext-1",
                "severity" : "error",
                "human" : "Must have either extensions or value[x], not both",
                "expression" : "extension.exists() != value.exists()",
                "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
                "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
              }
            ],
            "isModifier" : true,
            "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
            "isSummary" : true,
            "mapping" : [
              {
                "identity" : "rim",
                "map" : "N/A"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.completeRemission",
            "path" : "FrontLineTreatment.notForRelapse.completeRemission",
            "short" : "Complete remission",
            "definition" : "Complete remission",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.notForRelapse.completeRemission",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "BackboneElement"
              }
            ],
            "constraint" : [
              {
                "key" : "ele-1",
                "severity" : "error",
                "human" : "All FHIR elements must have a @value or children",
                "expression" : "hasValue() or (children().count() > id.count())",
                "xpath" : "@value|f:*|h:div",
                "source" : "http://hl7.org/fhir/StructureDefinition/Element"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "outcome"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.completeRemission.id",
            "path" : "FrontLineTreatment.notForRelapse.completeRemission.id",
            "representation" : [
              "xmlAttr"
            ],
            "short" : "Unique id for inter-element referencing",
            "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "Element.id",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                    "valueUrl" : "string"
                  }
                ],
                "code" : "http://hl7.org/fhirpath/System.String"
              }
            ],
            "isModifier" : false,
            "isSummary" : false,
            "mapping" : [
              {
                "identity" : "rim",
                "map" : "n/a"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.completeRemission.extension",
            "path" : "FrontLineTreatment.notForRelapse.completeRemission.extension",
            "slicing" : {
              "discriminator" : [
                {
                  "type" : "value",
                  "path" : "url"
                }
              ],
              "description" : "Extensions are always sliced by (at least) url",
              "rules" : "open"
            },
            "short" : "Additional content defined by implementations",
            "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
            "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
            "alias" : [
              "extensions",
              "user content"
            ],
            "min" : 0,
            "max" : "*",
            "base" : {
              "path" : "Element.extension",
              "min" : 0,
              "max" : "*"
            },
            "type" : [
              {
                "code" : "Extension"
              }
            ],
            "constraint" : [
              {
                "key" : "ele-1",
                "severity" : "error",
                "human" : "All FHIR elements must have a @value or children",
                "expression" : "hasValue() or (children().count() > id.count())",
                "xpath" : "@value|f:*|h:div",
                "source" : "http://hl7.org/fhir/StructureDefinition/Element"
              },
              {
                "key" : "ext-1",
                "severity" : "error",
                "human" : "Must have either extensions or value[x], not both",
                "expression" : "extension.exists() != value.exists()",
                "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
                "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
              }
            ],
            "isModifier" : false,
            "isSummary" : false,
            "mapping" : [
              {
                "identity" : "rim",
                "map" : "n/a"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.completeRemission.modifierExtension",
            "path" : "FrontLineTreatment.notForRelapse.completeRemission.modifierExtension",
            "short" : "Extensions that cannot be ignored even if unrecognized",
            "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
            "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
            "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
            "alias" : [
              "extensions",
              "user content",
              "modifiers"
            ],
            "min" : 0,
            "max" : "*",
            "base" : {
              "path" : "BackboneElement.modifierExtension",
              "min" : 0,
              "max" : "*"
            },
            "type" : [
              {
                "code" : "Extension"
              }
            ],
            "constraint" : [
              {
                "key" : "ele-1",
                "severity" : "error",
                "human" : "All FHIR elements must have a @value or children",
                "expression" : "hasValue() or (children().count() > id.count())",
                "xpath" : "@value|f:*|h:div",
                "source" : "http://hl7.org/fhir/StructureDefinition/Element"
              },
              {
                "key" : "ext-1",
                "severity" : "error",
                "human" : "Must have either extensions or value[x], not both",
                "expression" : "extension.exists() != value.exists()",
                "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
                "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
              }
            ],
            "isModifier" : true,
            "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
            "isSummary" : true,
            "mapping" : [
              {
                "identity" : "rim",
                "map" : "N/A"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.completeRemission.status",
            "path" : "FrontLineTreatment.notForRelapse.completeRemission.status",
            "short" : "Complete remission (Yes/No)",
            "definition" : "Complete remission (Yes/No)",
            "min" : 1,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.notForRelapse.completeRemission.status",
              "min" : 1,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "dateTime"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "outcome.coding"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.completeRemission.description",
            "path" : "FrontLineTreatment.notForRelapse.completeRemission.description",
            "short" : "Textual description in case of no remission",
            "definition" : "Textual description in case of no remission",
            "min" : 1,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.notForRelapse.completeRemission.description",
              "min" : 1,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "outcome.text"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.isProgressionRelapseDuringFLT",
            "path" : "FrontLineTreatment.notForRelapse.isProgressionRelapseDuringFLT",
            "short" : "Progression/relapse during frontline treatment ?",
            "definition" : "Progression/relapse during frontline treatment ?",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.notForRelapse.isProgressionRelapseDuringFLT",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Condition.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Condition-primaryCancer-eu-pcsp').where( (extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/condition-previousStatus').valueCode = #replaspe or #recurrence) and  ( onsetDateTime < Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-flt-eu-pcsp').performedPeriod.end) ).exists()"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.isProgressionRelapseAfterFLT",
            "path" : "FrontLineTreatment.notForRelapse.isProgressionRelapseAfterFLT",
            "short" : "Progression/relapse after first elective end of treatment ?",
            "definition" : "Progression/relapse after first elective end of treatment ?",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "FrontLineTreatment.notForRelapse.isProgressionRelapseAfterFLT",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Condition.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Condition-primaryCancer-eu-pcsp').where( (extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/condition-previousStatus').valueCode = #replaspe or #recurrence) and  ( onsetDateTime >= Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-flt-eu-pcsp').performedPeriod.end) ).exists()"
              }
            ]
          }
        ]
      },
      "differential" : {
        "element" : [
          {
            "id" : "FrontLineTreatment",
            "path" : "FrontLineTreatment",
            "short" : "Front Line Treatment",
            "definition" : "Front Line Treatment. The first treatment given for a disease. It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation. When used by itself, first-line therapy is the one accepted as the best treatment. If it does not cure the disease or it causes severe side effects, other treatment may be added or used instead. Also called induction therapy, primary therapy, and primary treatment.",
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-flt-eu-pcsp')"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol",
            "path" : "FrontLineTreatment.followedProtocol",
            "short" : "Followed Protocol",
            "definition" : "Followed Protocol",
            "min" : 0,
            "max" : "*",
            "type" : [
              {
                "code" : "BackboneElement"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".instantiatesCanonical"
              },
              {
                "identity" : "fhir",
                "map" : "PlanDefinition.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/PlanDefinition-flt-eu-pcsp')"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.type",
            "path" : "FrontLineTreatment.followedProtocol.type",
            "short" : "Protocole type",
            "definition" : "2 => Trial/protocol\n2 => Personalized\n3 => Guidelines\n-9922 => NK",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".type"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.name",
            "path" : "FrontLineTreatment.followedProtocol.name",
            "short" : "Protocole name",
            "definition" : "Protocole name",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "string"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".title"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.description",
            "path" : "FrontLineTreatment.followedProtocol.description",
            "short" : "Protocol name or description",
            "definition" : "If a specific trial/protocol was used, please specify.  \nIn case of relapse/progression during front line treatment,please report both the name of the front line as well of the salvage treatment\nIf personalized, please specify.  ",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "string"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".description"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.followedProtocol.arm",
            "path" : "FrontLineTreatment.followedProtocol.arm",
            "short" : "Group/Arm/Randomization",
            "definition" : "If the trial was randomized, please define randomization arm",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "string"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : ".extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/procedure-fltArm').valueString"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.dateEOT",
            "path" : "FrontLineTreatment.dateEOT",
            "short" : "Date of end of treatment",
            "definition" : "It might be the date of first elective end of treatment, or that of the second (or further) end of treatment after the first one. If the date is unkown or partially missed insert the year at the best of your knowledge.",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "dateTime"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.performedPeriod.end"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.isChemotherapy",
            "path" : "FrontLineTreatment.isChemotherapy",
            "short" : "Chemotherapy ?",
            "definition" : "Chemotherapy ?",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "MedicationAdministration.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/MedicationAdministration-eu-pcsp').exists()"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.isStemCellTransplantation",
            "path" : "FrontLineTreatment.isStemCellTransplantation",
            "short" : "Stem Cell transplantation ?",
            "definition" : "Stem Cell transplantation ?",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-eu-pcsp').exists()"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.isRadiotherapy",
            "path" : "FrontLineTreatment.isRadiotherapy",
            "short" : "Radiotherapy ?",
            "definition" : "Radiotherapy ?",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-radiotheraphy-eu-pcsp').exists()"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.isMajorSurgery",
            "path" : "FrontLineTreatment.isMajorSurgery",
            "short" : "Major Surgery ?",
            "definition" : "Major Surgery ?",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-surgery-eu-pcsp').exists().not() [No Case, implicit]"
              },
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-surgery-eu-pcsp')..where(code = 'no-known-procedures').exists() [No Case, explicit]"
              },
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-surgery-eu-pcsp').where(code != 'no-known-procedures' or code != 'no-procedure-info').exists() [Yes Case]"
              },
              {
                "identity" : "fhir",
                "map" : "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-surgery-eu-pcsp').where(code = 'no-procedure-info').exists() [Unk case]"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse",
            "path" : "FrontLineTreatment.notForRelapse",
            "short" : "Details not provided for relapses after EOT",
            "definition" : "Details not provided for relapses after EOT",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "BackboneElement"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.completeRemission",
            "path" : "FrontLineTreatment.notForRelapse.completeRemission",
            "short" : "Complete remission",
            "definition" : "Complete remission",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "BackboneElement"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "outcome"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.completeRemission.status",
            "path" : "FrontLineTreatment.notForRelapse.completeRemission.status",
            "short" : "Complete remission (Yes/No)",
            "definition" : "Complete remission (Yes/No)",
            "min" : 1,
            "max" : "1",
            "type" : [
              {
                "code" : "dateTime"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "outcome.coding"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.completeRemission.description",
            "path" : "FrontLineTreatment.notForRelapse.completeRemission.description",
            "short" : "Textual description in case of no remission",
            "definition" : "Textual description in case of no remission",
            "min" : 1,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "outcome.text"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.isProgressionRelapseDuringFLT",
            "path" : "FrontLineTreatment.notForRelapse.isProgressionRelapseDuringFLT",
            "short" : "Progression/relapse during frontline treatment ?",
            "definition" : "Progression/relapse during frontline treatment ?",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Condition.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Condition-primaryCancer-eu-pcsp').where( (extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/condition-previousStatus').valueCode = #replaspe or #recurrence) and  ( onsetDateTime < Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-flt-eu-pcsp').performedPeriod.end) ).exists()"
              }
            ]
          },
          {
            "id" : "FrontLineTreatment.notForRelapse.isProgressionRelapseAfterFLT",
            "path" : "FrontLineTreatment.notForRelapse.isProgressionRelapseAfterFLT",
            "short" : "Progression/relapse after first elective end of treatment ?",
            "definition" : "Progression/relapse after first elective end of treatment ?",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ],
            "mapping" : [
              {
                "identity" : "fhir",
                "map" : "Condition.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Condition-primaryCancer-eu-pcsp').where( (extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/condition-previousStatus').valueCode = #replaspe or #recurrence) and  ( onsetDateTime >= Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-flt-eu-pcsp').performedPeriod.end) ).exists()"
              }
            ]
          }
        ]
      }
    }