# Additive/Preservative (2.5 - 2.0.0) - HL7 v2.5 Vocabulary v0.1.0

* [**Table of Contents**](toc.md)
* [**Artifacts Summary**](artifacts.md)
* **Additive/Preservative (2.5 - 2.0.0)**

## CodeSystem: Additive/Preservative (2.5 - 2.0.0) (Experimental) 

| | |
| :--- | :--- |
| *Official URL*:http://terminology.hl7.org/v2plusvocab/CodeSystem/additivePreservative | *Version*:2.0.0 |
| Active as of 2026-01-27 | *Computable Name*:AdditivePreservative |
| *Other Identifiers:*OID:2.16.840.1.113883.18.229 | |
| **Copyright/Legal**: HL7 Inc., 2026 | |

 
HL7-defined code system of concepts specifying any additive introduced to the specimen before or at the time of collection. These additives may be introduced in order to preserve, maintain or enhance the particular nature or component of the specimen. Used in HL7 Version 2.x messaging in the SPM and SAC segments. 

 This Code system is referenced in the content logical definition of the following value sets: 

* [Hl7VSadditivePreservative](ValueSet-hl7VSadditivePreservative.md)



## Resource Content

```json
{
  "resourceType" : "CodeSystem",
  "id" : "additivePreservative",
  "extension" : [
    {
      "url" : "http://terminology.hl7.org/v2plusvocab/StructureDefinition/codesystem-v2versionCreated",
      "valueString" : "2.5"
    },
    {
      "url" : "http://terminology.hl7.org/v2plusvocab/StructureDefinition/codesystem-versionHistory",
      "valueString" : "generate correct history somehow"
    },
    {
      "url" : "http://terminology.hl7.org/v2plusvocab/StructureDefinition/codesystem-tableNo",
      "valueString" : "0371"
    }
  ],
  "url" : "http://terminology.hl7.org/v2plusvocab/CodeSystem/additivePreservative",
  "identifier" : [
    {
      "system" : "urn:ietf:rfc:3986",
      "value" : "urn:oid:2.16.840.1.113883.18.229"
    }
  ],
  "version" : "2.0.0",
  "name" : "AdditivePreservative",
  "title" : "Additive/Preservative (2.5 - 2.0.0)",
  "status" : "active",
  "experimental" : true,
  "date" : "2026-01-27T19:23:43+00:00",
  "publisher" : "HL7/FO",
  "contact" : [
    {
      "name" : "HL7/FO",
      "telecom" : [
        {
          "system" : "url",
          "value" : "http://www.hl7.org"
        }
      ]
    }
  ],
  "description" : "HL7-defined code system of concepts specifying any additive introduced to the specimen before or at the time of collection.  These additives may be introduced in order to preserve, maintain or enhance the particular nature or component of the specimen.  Used in HL7 Version 2.x messaging in the SPM and SAC segments.",
  "copyright" : "HL7 Inc., 2026",
  "caseSensitive" : true,
  "compositional" : false,
  "content" : "complete",
  "property" : [
    {
      "code" : "versionIntroduced",
      "uri" : "http://terminology.hl7.org/v2plusvocab/CodeSystem/Property#versionIntroduced",
      "description" : "version when was this code introduced",
      "type" : "string"
    },
    {
      "code" : "versionDeprecated",
      "uri" : "http://terminology.hl7.org/v2plusvocab/CodeSystem/Property#versionDeprecated",
      "description" : "version when was this code deprecated",
      "type" : "string"
    },
    {
      "code" : "status",
      "uri" : "http://hl7.org/fhir/concept-properties#status",
      "description" : "A code that indicates the status of the concept. Typical values are active, experimental, deprecated, and retired",
      "type" : "code"
    },
    {
      "code" : "comment",
      "uri" : "http://terminology.hl7.org/v2plusvocab/CodeSystem/Property#comment",
      "description" : "A string that provides additional detail pertinent to the use or understanding of the concept",
      "type" : "string"
    },
    {
      "code" : "usage",
      "uri" : "http://terminology.hl7.org/v2plusvocab/CodeSystem/Property#usage",
      "description" : "usage notes for this code",
      "type" : "string"
    },
    {
      "code" : "modified",
      "uri" : "http://terminology.hl7.org/v2plusvocab/CodeSystem/Property#modified",
      "description" : "date of last modification",
      "type" : "dateTime"
    }
  ],
  "concept" : [
    {
      "code" : "ACDA",
      "display" : "ACD Solution A",
      "definition" : "ACD Solution A",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "ACDB",
      "display" : "ACD Solution B",
      "definition" : "ACD Solution B",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "ACET",
      "display" : "Acetic Acid",
      "definition" : "Acetic Acid",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "AMIES",
      "display" : "Amies transport medium",
      "definition" : "Amies transport medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "BACTM",
      "display" : "Bacterial Transport medium",
      "definition" : "Bacterial Transport medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "BF10",
      "display" : "Buffered 10% formalin",
      "definition" : "Buffered 10% formalin",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "BOR",
      "display" : "Borate Boric Acid",
      "definition" : "Borate Boric Acid",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.4"
        }
      ]
    },
    {
      "code" : "BOUIN",
      "display" : "Bouin's solution",
      "definition" : "Bouin's solution",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "BSKM",
      "display" : "Buffered skim milk",
      "definition" : "Buffered skim milk",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "C32",
      "display" : "3.2%  Citrate",
      "definition" : "3.2%  Citrate",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.4"
        }
      ]
    },
    {
      "code" : "C38",
      "display" : "3.8% Citrate",
      "definition" : "3.8% Citrate",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.4"
        }
      ]
    },
    {
      "code" : "CARS",
      "display" : "Carson's Modified 10% formalin",
      "definition" : "Carson's Modified 10% formalin",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "CARY",
      "display" : "Cary Blair Medium",
      "definition" : "Cary Blair Medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "CHLTM",
      "display" : "Chlamydia transport medium",
      "definition" : "Chlamydia transport medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "CTAD",
      "display" : "CTAD (this should be spelled out if not universally understood)",
      "definition" : "CTAD (this should be spelled out if not universally understood)",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "EDTK",
      "display" : "Potassium/K EDTA",
      "definition" : "Potassium/K EDTA",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.4"
        }
      ]
    },
    {
      "code" : "EDTK15",
      "display" : "Potassium/K EDTA 15%",
      "definition" : "Potassium/K EDTA 15%",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "EDTK75",
      "display" : "Potassium/K EDTA 7.5%",
      "definition" : "Potassium/K EDTA 7.5%",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "EDTN",
      "display" : "Sodium/Na EDTA",
      "definition" : "Sodium/Na EDTA",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.4"
        }
      ]
    },
    {
      "code" : "ENT",
      "display" : "Enteric bacteria transport medium",
      "definition" : "Enteric bacteria transport medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "ENT+",
      "display" : "Enteric plus",
      "definition" : "Enteric plus",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "F10",
      "display" : "10% Formalin",
      "definition" : "10% Formalin",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "FDP",
      "display" : "Thrombin NIH; soybean trypsin inhibitor (Fibrin Degradation Products)",
      "definition" : "Thrombin NIH; soybean trypsin inhibitor (Fibrin Degradation Products)",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "FL10",
      "display" : "Sodium Fluoride, 10mg",
      "definition" : "Sodium Fluoride, 10mg",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "FL100",
      "display" : "Sodium Fluoride, 100mg",
      "definition" : "Sodium Fluoride, 100mg",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "HCL6",
      "display" : "6N HCL",
      "definition" : "6N HCL",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.4"
        }
      ]
    },
    {
      "code" : "HEPA",
      "display" : "Ammonium heparin",
      "definition" : "Ammonium heparin",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "HEPL",
      "display" : "Lithium/Li  Heparin",
      "definition" : "Lithium/Li  Heparin",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.4"
        }
      ]
    },
    {
      "code" : "HEPN",
      "display" : "Sodium/Na  Heparin",
      "definition" : "Sodium/Na  Heparin",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.4"
        }
      ]
    },
    {
      "code" : "HNO3",
      "display" : "Nitric Acid",
      "definition" : "Nitric Acid",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "JKM",
      "display" : "Jones Kendrick Medium",
      "definition" : "Jones Kendrick Medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "KARN",
      "display" : "Karnovsky's fixative",
      "definition" : "Karnovsky's fixative",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "KOX",
      "display" : "Potassium Oxalate",
      "definition" : "Potassium Oxalate",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "LIA",
      "display" : "Lithium iodoacetate",
      "definition" : "Lithium iodoacetate",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "M4",
      "display" : "M4",
      "definition" : "M4",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "M4RT",
      "display" : "M4-RT",
      "definition" : "M4-RT",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "M5",
      "display" : "M5",
      "definition" : "M5",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "MICHTM",
      "display" : "Michel's transport medium",
      "definition" : "Michel's transport medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "MMDTM",
      "display" : "MMD transport medium",
      "definition" : "MMD transport medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "NAF",
      "display" : "Sodium Fluoride",
      "definition" : "Sodium Fluoride",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "NAPS",
      "display" : "Sodium polyanethol sulfonate 0.35% in 0.85% sodium chloride",
      "definition" : "Sodium polyanethol sulfonate 0.35% in 0.85% sodium chloride",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "NONE",
      "display" : "None",
      "definition" : "None",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "PAGE",
      "display" : "Pages's Saline",
      "definition" : "Pages's Saline",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "PHENOL",
      "display" : "Phenol",
      "definition" : "Phenol",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "PVA",
      "display" : "PVA (polyvinylalcohol)",
      "definition" : "PVA (polyvinylalcohol)",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "RLM",
      "display" : "Reagan Lowe Medium",
      "definition" : "Reagan Lowe Medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "SILICA",
      "display" : "Siliceous earth, 12 mg",
      "definition" : "Siliceous earth, 12 mg",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "SPS",
      "display" : "SPS(this should be spelled out if not universally understood)",
      "definition" : "SPS(this should be spelled out if not universally understood)",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "SST",
      "display" : "Serum Separator Tube (Polymer Gel)",
      "definition" : "Serum Separator Tube (Polymer Gel)",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "STUTM",
      "display" : "Stuart transport medium",
      "definition" : "Stuart transport medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "THROM",
      "display" : "Thrombin",
      "definition" : "Thrombin",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "THYMOL",
      "display" : "Thymol",
      "definition" : "Thymol",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "THYO",
      "display" : "Thyoglycollate broth",
      "definition" : "Thyoglycollate broth",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "TOLU",
      "display" : "Toluene",
      "definition" : "Toluene",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "URETM",
      "display" : "Ureaplasma transport medium",
      "definition" : "Ureaplasma transport medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "VIRTM",
      "display" : "Viral Transport medium",
      "definition" : "Viral Transport medium",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    },
    {
      "code" : "WEST",
      "display" : "Buffered Citrate (Westergren Sedimentation Rate)",
      "definition" : "Buffered Citrate (Westergren Sedimentation Rate)",
      "property" : [
        {
          "code" : "versionIntroduced",
          "valueString" : "2.5"
        }
      ]
    }
  ]
}

```
