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Order for opioid analgesics with ambulatory misuse potential?	Yes	Trigger based on a new prescription (order) for opioid analgesics with ambulatory misuse potential - ideally the prescription should be selected prior to being committed to the system	Opioid analgesics with ambulatory misuse potential	MedicationRequest	MedicationRequest.medication, and MedicationRequest.category
Order for benzodiazepine or other central nervous system depressant medications?	Yes	Trigger based on a new prescription (order) for opioids or benzodiazepines or other central nervous system depressant in the relevant value sets - ideally the prescription should be selected prior to being committed to the system	Benzodiazepine or other central nervous system depressant medications	MedicationRequest	MedicationRequest.medication, and MedicationRequest.category
Receiving both opioid with ambulatory use potential and benzodiazepine or other central nervous system depressant ?	Yes	New prescription is for an opioid and existing use of benzodiazepine or other central nervous system depressant evident, OR New prescription is for benzodiazepine or other central nervous system depressant and existing use of opioids evident	Opioid analgesics with ambulatory misuse potential Benzodiazepine or other central nervous system depressant medications	MedicationRequest	MedicationRequest.medication, and MedicationRequest.category