2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide
2022.1.0 - CI Build

2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide, published by Centers for Disease Control and Prevention (CDC). This guide is not an authorized publication; it is the continuous build for version 2022.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/cqframework/opioid-cds-r4/ and changes regularly. See the Directory of published versions

: PlanDefinition - 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain: Recommendation #11 - XML Representation

Draft as of 2023-05-01

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<PlanDefinition xmlns="http://hl7.org/fhir">
  <id value="opioidcds-11"/>
  <meta>
    <profile
             value="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-recommendationdefinition"/>
    <profile
             value="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-publishableplandefinition"/>
  </meta>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
    <table class="grid dict">
        
        <tr>
            <th scope="row"><b>Id: </b></th>
            <td style="padding-left: 4px;">opioidcds-11</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Url: </b></th>
            <td style="padding-left: 4px;"><a href="PlanDefinition-opioidcds-11.html">PlanDefinition - 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain: Recommendation #11</a></td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Version: </b></th>
            <td style="padding-left: 4px;">2022.1.0</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Identifier: </b></th>
            <td style="padding-left: 4px;">
                
                
                <p style="margin-bottom: 5px;">
                    <b>value: </b> <span>cdc-opioid-guidance</span>
                </p>
                
            </td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Name: </b></th>
            <td style="padding-left: 4px;">CDC_opioid_11</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Title: </b></th>
            <td style="padding-left: 4px;">PlanDefinition - 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain: Recommendation #11</td>
        </tr>
        
        
        
        <tr>
            <th scope="row"><b>Status: </b></th>
            <td style="padding-left: 4px;">draft</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Experimental: </b></th>
            <td style="padding-left: 4px;">true</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Type: </b></th>
            <td style="padding-left: 4px;">
                
                    
                        
                        <p style="margin-bottom: 5px;">
                            <b>system: </b> <span><a href="http://hl7.org/fhir/R4/codesystem-plan-definition-type.html">http://terminology.hl7.org/CodeSystem/plan-definition-type</a></span>
                        </p>
                        
                        
                        <p style="margin-bottom: 5px;">
                            <b>code: </b> <span>eca-rule</span>
                        </p>
                        
                        
                        <p style="margin-bottom: 5px;">
                            <b>display: </b> <span>ECA Rule</span>
                        </p>
                        
                    
                
                
            </td>
        </tr>
        
        
        
        <tr>
            <th scope="row"><b>Date: </b></th>
            <td style="padding-left: 4px;">2023-05-01</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Publisher: </b></th>
            <td style="padding-left: 4px;">Centers for Disease Control and Prevention (CDC)</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Description: </b></th>
            <td style="padding-left: 4px;">Concurrently prescribing opioid medications with benzodiazepines increases the risk of harm for the patient.</td>
        </tr>
        
        
            <tr>
                <th scope="row"><a name="effective-data-requirements"> </a><b>Logic Definitions: </b></th>
                <td style="padding-left: 4px;">
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Get Summary</td>
                                
                                
                                    <td>0</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Get Summary&quot;:
  if &quot;Is Recommendation Applicable?&quot;
    then 'Avoid prescribing opioid pain medication and benzodiazepine concurrently whenever possible.'
  else null</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Opioid Analgesic with Ambulatory Misuse Potential Prescriptions</td>
                                
                                
                                    <td>1</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Opioid Analgesic with Ambulatory Misuse Potential Prescriptions&quot;:
  Common.&quot;Is Opioid Analgesic with Ambulatory Misuse Potential?&quot;( ContextPrescriptions )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential</td>
                                
                                
                                    <td>2</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential&quot;:
  exists( &quot;Opioid Analgesic with Ambulatory Misuse Potential Prescriptions&quot; )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>Active Ambulatory Benzodiazepine Rx</td>
                                
                                
                                    <td>3</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Active Ambulatory Benzodiazepine Rx&quot;:
    if Config.&quot;Can the implementing EHR support queries for past medications by date range?&quot; then
      (
        &quot;Get MedicationRequest Medication as Code&quot;(&quot;Get Active Ambulatory Medication Requests&quot;([MedicationRequest]))
      ) Rx
        where date from Rx.authoredOn 2 years or less on or before Today()
          and Rx.medication in &quot;Benzodiazepine medications&quot;
    else
         List&lt;FHIR.MedicationRequest&gt;{}</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Benzodiazepine Prescriptions</td>
                                
                                
                                    <td>4</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Benzodiazepine Prescriptions&quot;:
  Common.&quot;Is Benzodiazepine?&quot;( ContextPrescriptions )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Patient Is Being Prescribed Benzodiazepine</td>
                                
                                
                                    <td>5</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Patient Is Being Prescribed Benzodiazepine&quot;:
  exists( &quot;Benzodiazepine Prescriptions&quot; )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>Active Ambulatory Opioid Rx</td>
                                
                                
                                    <td>6</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Active Ambulatory Opioid Rx&quot;:
    if Config.&quot;Can the implementing EHR support queries for past medications by date range?&quot; then
      (
        &quot;Get MedicationRequest Medication as Code&quot;(&quot;Get Active Ambulatory Medication Requests&quot;([MedicationRequest]))
      ) Rx
        where date from Rx.authoredOn 2 years or less on or before Today()
          and Rx.medication in &quot;Opioid analgesics with ambulatory misuse potential&quot;
    else
        List&lt;FHIR.MedicationRequest&gt;{}</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Patient Age Less Than 18</td>
                                
                                
                                    <td>7</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Patient Age Less Than 18&quot;:
  if (Config.&quot;Age Less than 18 Years Is Enabled&quot;) then
    AgeInYearsAt(Today()) &lt; 18
  else
    false</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Condition Positive for Sickle Cell</td>
                                
                                
                                    <td>8</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Condition Positive for Sickle Cell&quot;:
      if (Config.&quot;Sickle Cell Check Enabled&quot;) then
        exists(
            Common.&quot;Positive Sickle Cell Condition&quot;
        )  else
        false</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>US Core-Categorized Conditions</td>
                                
                                
                                    <td>9</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// 3. Medications indicating end of life
    /* or exists (
      &quot;Medications Indicating End of Life&quot;
    ) */
define &quot;US Core-Categorized Conditions&quot;:
  [Condition: category in &quot;Encounter Diagnosis Condition Category&quot;]
    union [Condition: category in &quot;Problem List Condition Category&quot;]
    union [Condition: category in &quot;US Core Health Concern Condition Category&quot;]</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Conditions Indicating End Of Life Present</td>
                                
                                
                                    <td>10</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Conditions Indicating End Of Life Present&quot;:
  exists (
    Common.&quot;US Core-Categorized Conditions&quot; LLEC
      where LLEC.code in Common.&quot;Limited life expectancy conditions&quot;
        and LLEC.clinicalStatus in Common.&quot;Active Condition&quot;
  )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>Service Requests</td>
                                
                                
                                    <td>11</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Service Requests&quot;:
   [ServiceRequest] SR
    return SR</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Palliative Care Lookback Period</td>
                                
                                
                                    <td>12</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">/*
**  Routine #1
**  Opioid Review Useful Routine
**
**  Definition              | Answer to Proceed   | Details                                      | Data (Terminology) Requirement
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Age &lt; 18 years?         | No                  | Calculate age from date of birth; exclude    | Date of birth
**                          |                     | patients with age less than 18 years at the  |
**                          |                     | time of the prescription                     |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Evidence of             | No                  | Look for documented findings consistent      | Sickle cell disease conditions
**  sickle cell disease?    |                     | with those listed in the sickle cell         |
**                          |                     | value set                                    |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Limited life            | No                  | Look for documented findings consistent      | Limited life expectancy conditions
**  expectancy conditions   |                     | with those listed in the limited life        |
**  present?                |                     | expectancy value set (terminal illness, bad  |
**                          |                     | prognosis, pre-terminal)                     |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Order for therapies     | No                  | Look for patients with an existing order for | Therapies indicating end of life care
**  indicating end of life  |                     | therapies indicating end of life care        |
**  care in past 90 days?   |                     | written within past 90 days                  |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Active cancer           | No                  | See sub-routine 3                            | See sub-routine 3
**  treatment?              |                     |                                              |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Conditions Likely       | No                  | Look for patients with active conditions in  | Conditions likely terminal for opioid
**  Terminal for opioid     |                     | the value set end-of-life-conditions         | prescribing
**  prescribing present?    |                     |                                              |
**  ------------------------------------------------------------------------------------------------------------------------------------
**
*/
define &quot;Palliative Care Lookback Period&quot;:
  Interval[Today() - 90 days, Today()]</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Order For Palliative Care In Past 90 Days</td>
                                
                                
                                    <td>13</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Order For Palliative Care In Past 90 Days&quot;:
  exists (
    Common.&quot;Service Requests&quot; SR
    where SR.status in { 'active', 'completed'}
      and SR.intent in {'proposal', 'plan,', 'directive', 'order', 'original-order', 'reflex-order', 'filler-order', 'instance-order'}
      and FHIRHelpers.ToDateTime(SR.authoredOn) during day of &quot;Palliative Care Lookback Period&quot;
      and SR.code in Common.&quot;Therapies indicating end of life care&quot;
  )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Is Active Cancer Treatment?</td>
                                
                                
                                    <td>14</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Is Active Cancer Treatment?&quot;:
  if (Config.&quot;Active Cancer Treatment Encounters Condition Is Enabled&quot;) then
      &quot;Has Two or More Encounters with Cancer Diagnosis During Encounter Period&quot;
    else
      false</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Conditions Including Cancer To Exclude Opioid Management Indicating End-Stage Disease Present</td>
                                
                                
                                    <td>15</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Conditions Including Cancer To Exclude Opioid Management Indicating End-Stage Disease Present&quot;:
  if (Config.&quot;End-Stage Disease Criteria Enabled&quot;) then
    exists (
      Common.&quot;US Core-Categorized Conditions&quot; EOLC
        where EOLC.code in Common.&quot;Conditions likely terminal for opioid prescribing&quot;
          and EOLC.clinicalStatus in Common.&quot;Active Condition&quot;
    )
  else
    false</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Is Opioid Review Useful?</td>
                                
                                
                                    <td>16</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Is Opioid Review Useful?&quot;:
  not &quot;Patient Age Less Than 18&quot;
    and not &quot;Condition Positive for Sickle Cell&quot;
    and not &quot;Conditions Indicating End Of Life Present&quot;
    and not &quot;Order For Palliative Care In Past 90 Days&quot;
    and not &quot;Is Active Cancer Treatment?&quot;
    and not &quot;Conditions Including Cancer To Exclude Opioid Management Indicating End-Stage Disease Present&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Inclusion Criteria</td>
                                
                                
                                    <td>17</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Inclusion Criteria&quot;:
  (
    (
      &quot;Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential&quot;
        and exists Common.&quot;Active Ambulatory Benzodiazepine Rx&quot;
    )
      or (
        &quot;Patient Is Being Prescribed Benzodiazepine&quot;
          and exists Common.&quot;Active Ambulatory Opioid Rx&quot;
      )
  )
    and Routines.&quot;Is Opioid Review Useful?&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>Conditions Indicating End of Life or With Limited Life Expectancy</td>
                                
                                
                                    <td>18</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Conditions Indicating End of Life or With Limited Life Expectancy&quot;:
  (
    &quot;US Core-Categorized Conditions&quot; C
      where C.code in &quot;Conditions likely terminal for opioid prescribing&quot;
        and C.clinicalStatus in &quot;Active Condition&quot;
  )
  union
  (
    &quot;US Core-Categorized Conditions&quot; C
      where C.code in &quot;Limited life expectancy conditions&quot;
        and C.clinicalStatus in &quot;Active Condition&quot;
  )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>Admitted/Referred/Discharged to Hospice Care</td>
                                
                                
                                    <td>19</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Admitted/Referred/Discharged to Hospice Care&quot;:
  (
    [Procedure: code in &quot;Hospice Procedure Codes&quot;] P
      where P.status.value in { 'in-progress', 'completed' }
  )
  union
  (
    &quot;Service Requests&quot; SR
      where SR.code in &quot;Hospice Procedure Codes&quot;
        and SR.status.value in { 'active', 'completed' }
  )
  union
  (
    if (Config.&quot;Hospice Findings Exclusion Enabled&quot;) then
      [Observation: code in &quot;Hospice Finding Codes&quot;] O
        where not (O.status.value in { 'unknown', 'entered-in-error', 'cancelled' })
    else
      {}
  )
  union
  (
    [Encounter] E
      where date from E.period.start 1 year or less on or before Today()
        and (
          if E.hospitalization.dischargeDisposition.coding is null
              or not exists (E.hospitalization.dischargeDisposition.coding)
            then false
          else E.hospitalization.dischargeDisposition in &quot;Hospice Disposition&quot;
        )
        and E.status.value in { 'planned', 'arrived', 'in-progress', 'finished', 'onleave' }
  )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>End of Life Assessment</td>
                                
                                
                                    <td>20</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;End of Life Assessment&quot;:
    // 1. Conditions indicating end of life or with limited life expectancy
    exists (
      &quot;Conditions Indicating End of Life or With Limited Life Expectancy&quot;
    )
    // 2. Admitted/referred/discharged to hospice care
    or exists (
      &quot;Admitted/Referred/Discharged to Hospice Care&quot;
    )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Exclusion Criteria</td>
                                
                                
                                    <td>21</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Exclusion Criteria&quot;:
  Common.&quot;End of Life Assessment&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Is Recommendation Applicable?</td>
                                
                                
                                    <td>22</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Is Recommendation Applicable?&quot;:
  &quot;Inclusion Criteria&quot;
    and not &quot;Exclusion Criteria&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Get Detail</td>
                                
                                
                                    <td>23</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Get Detail&quot;:
  if &quot;Is Recommendation Applicable?&quot;
    then
      'Consider whether the benefits outweigh the risks of concurrently prescribing opioids and benzodiazepines, or other central nervous system depressant medications.

When co-prescribing risks outweigh benefits, consult the [2022 CDC Clinical Practice Guideline Recommendation 11](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=evidence%20type%3A%203).-,Implementation%20Considerations,-Although%20in%20some) for further guidance.

[For patients being treated for opioid use disorder who are also taking benzodiazepines or other medications that depress the central nervous system, the CDC recommends not withholding buprenorphine or methadone](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=gabapentin%20and%20pregabalin).-,Buprenorphine%20or%20methadone%20for%20opioid%20use%20disorder%20should%20not%20be%20withheld%20from%20patients%20taking%20benzodiazepines%20or%20other%20medications%20that%20depress%20the%20central%20nervous%20system.,-Clinicians%20should%20check).

If the decision is made to taper benzodiazepine medications, [the CDC recommends tapering benzodiazepines gradually prior to discontinuation](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=Clinicians%20should%20taper%20benzodiazepines%20gradually%20before%20discontinuation%20because%20abrupt%20withdrawal%20can%20be%20associated%20with%20rebound%20anxiety%2C%20hallucinations%2C%20seizures%2C%20delirium%20tremens%2C%20and%2C%20rarely%2C%20death.%20The%20rate%20of%20tapering%20should%20be%20individualized).'
  else null</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC11</td>
                                
                                
                                    <td>Get Indicator</td>
                                
                                
                                    <td>24</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Get Indicator&quot;:
  if &quot;Is Recommendation Applicable?&quot;
    then 'warning'
  else null</code></pre>
                        
                        <br/><br/>
                    
                </td>
            </tr>
        
        
        <tr>
          <th scope="row"><b>Knowledge Capability: </b></th>
          <td style="padding-left: 4px;">
            shareable computable executable publishable 
          </td>
        </tr>
        
        
        
        <tr>
            <th scope="row"><b>Use Context: </b></th>
            <td style="padding-left: 4px;">
                <table class="grid-dict">
                    <tr><th><b>code</b></th><th><b>value</b></th><th><b>display</b></th></tr>
                    
                      <tr>
                        <td>focus</td>
                        <td>182888003</td>
                        <td>Medication requested (situation)</td>
                      </tr>
                    
                      <tr>
                        <td>focus</td>
                        <td>82423001</td>
                        <td>Chronic pain (finding)</td>
                      </tr>
                    
                </table>
            </td>
        </tr>
        
        
        
        <tr>
            <th scope="row"><b>Purpose: </b></th>
            <td style="padding-left: 4px;"><div><p>The 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain is intended to improve communication between providers and patients about the risks and benefits of opioid therapy for chronic pain, improve the safety and effectiveness of pain treatment, and reduce the risks associated with long-term opioid therapy, including opioid use disorder and overdose. The Guideline is not intended for patients who are in active cancer treatment, palliative care, or end-of-life care.</p>
</div></td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Usage: </b></th>
            <td style="padding-left: 4px;">Clinicians should avoid prescribing opioid pain medication and benzodiazepines or other central nervous system depressant concurrently whenever possible.</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Copyright: </b></th>
            <td style="padding-left: 4px;"><div><p>© CDC 2016+.</p>
</div></td>
        </tr>
        
        
        
        
        
        
        <tr>
          <th scope="row"><b>Related Artifacts: </b></th>
          <td style="padding-left: 4px;">
            
            <p><b>Documentation</b></p>
            <ul>
              
                  <li>
                    <a href="https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm"> 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain</a>
                  </li>
              
                  <li>
                    <a href="https://www.cdc.gov/drugoverdose/pdf/calculating_total_daily_dose-a.pdf"> MME Conversion Tables</a>
                  </li>
              
            </ul>
            
            
            
            
            
            
            
          </td>
        </tr>
        

        
        <tr>
          <th scope="row"><b>Libraries: </b></th>
          <td style="padding-left: 4px;">
            <table class="grid-dict">
              
                <tr><td><a href="Library-OpioidCDSREC11.html">Library - Recommendation #11 - Concurrent Use of Opioids and Benzodiazepines</a></td></tr>
              
            </table>
          </td>
        </tr>
        

        
        <tr>
          <th scope="row"><b>Actions: </b></th>
          <td style="padding-left: 4px;">
            <table class="grid-dict">
              
                <tr>
                  <td>
                    <b> Existing patient has concurrent opioid and benzodiazepine prescriptions.:</b> Checking if the trigger prescription meets the inclusion criteria for recommendation #11 workflow.<br/>
                    <b>When:</b> <i>Named Event:</i> order-select<br/>
                    <b>If:</b> <i>Applicability:</i> Check whether the existing patient is using opioids concurrently with benzodiazepines. <i>(Is Recommendation Applicable?)</i><br/>
                    <b>Then:</b>
                    
                      <table class="grid-dict">
                        
                          <tr>
                            <td>
                              <b> :</b> Document - Will modify prescription<br/>
                              
                              
                              <b>Then:</b>
                              
                                
                                
                              
                            </td>
                          </tr>
                        
                          <tr>
                            <td>
                              <b> :</b> Snooze* - Benefits outweigh risks, snooze 3 months<br/>
                              
                              
                              <b>Then:</b>
                              
                                
                                
                              
                            </td>
                          </tr>
                        
                          <tr>
                            <td>
                              <b> :</b> Snooze* - N/A see comment, snooze 3 months<br/>
                              
                              
                              <b>Then:</b>
                              
                                
                                
                              
                            </td>
                          </tr>
                        
                      </table>
                    
                  </td>
                </tr>
              
            </table>
          </td>
        </tr>
        
    </table>
</div>
  </text>
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      </relatedArtifact>
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        <resource
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      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
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        <resource
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      <parameter>
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        <type value="MedicationRequest"/>
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        <max value="1"/>
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      </parameter>
      <parameter>
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      </parameter>
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        <max value="1"/>
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      </parameter>
      <parameter>
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        <max value="1"/>
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      </parameter>
      <dataRequirement>
        <type value="Medication"/>
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      <dataRequirement>
        <type value="ServiceRequest"/>
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        <mustSupport value="intent"/>
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        <codeFilter>
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        <type value="ServiceRequest"/>
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        <mustSupport value="status.value"/>
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      (
        &quot;Get MedicationRequest Medication as Code&quot;(&quot;Get Active Ambulatory Medication Requests&quot;([MedicationRequest]))
      ) Rx
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      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Palliative Care Lookback Period"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="/*
**  Routine #1
**  Opioid Review Useful Routine
**
**  Definition              | Answer to Proceed   | Details                                      | Data (Terminology) Requirement
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Age &lt; 18 years?         | No                  | Calculate age from date of birth; exclude    | Date of birth
**                          |                     | patients with age less than 18 years at the  |
**                          |                     | time of the prescription                     |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Evidence of             | No                  | Look for documented findings consistent      | Sickle cell disease conditions
**  sickle cell disease?    |                     | with those listed in the sickle cell         |
**                          |                     | value set                                    |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Limited life            | No                  | Look for documented findings consistent      | Limited life expectancy conditions
**  expectancy conditions   |                     | with those listed in the limited life        |
**  present?                |                     | expectancy value set (terminal illness, bad  |
**                          |                     | prognosis, pre-terminal)                     |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Order for therapies     | No                  | Look for patients with an existing order for | Therapies indicating end of life care
**  indicating end of life  |                     | therapies indicating end of life care        |
**  care in past 90 days?   |                     | written within past 90 days                  |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Active cancer           | No                  | See sub-routine 3                            | See sub-routine 3
**  treatment?              |                     |                                              |
**  ------------------------------------------------------------------------------------------------------------------------------------
**  Conditions Likely       | No                  | Look for patients with active conditions in  | Conditions likely terminal for opioid
**  Terminal for opioid     |                     | the value set end-of-life-conditions         | prescribing
**  prescribing present?    |                     |                                              |
**  ------------------------------------------------------------------------------------------------------------------------------------
**
*/
define &quot;Palliative Care Lookback Period&quot;:
  Interval[Today() - 90 days, Today()]"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="12"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Order For Palliative Care In Past 90 Days"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Order For Palliative Care In Past 90 Days&quot;:
  exists (
    Common.&quot;Service Requests&quot; SR
    where SR.status in { 'active', 'completed'}
      and SR.intent in {'proposal', 'plan,', 'directive', 'order', 'original-order', 'reflex-order', 'filler-order', 'instance-order'}
      and FHIRHelpers.ToDateTime(SR.authoredOn) during day of &quot;Palliative Care Lookback Period&quot;
      and SR.code in Common.&quot;Therapies indicating end of life care&quot;
  )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="13"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Is Active Cancer Treatment?"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Is Active Cancer Treatment?&quot;:
  if (Config.&quot;Active Cancer Treatment Encounters Condition Is Enabled&quot;) then
      &quot;Has Two or More Encounters with Cancer Diagnosis During Encounter Period&quot;
    else
      false"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="14"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Conditions Including Cancer To Exclude Opioid Management Indicating End-Stage Disease Present"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Conditions Including Cancer To Exclude Opioid Management Indicating End-Stage Disease Present&quot;:
  if (Config.&quot;End-Stage Disease Criteria Enabled&quot;) then
    exists (
      Common.&quot;US Core-Categorized Conditions&quot; EOLC
        where EOLC.code in Common.&quot;Conditions likely terminal for opioid prescribing&quot;
          and EOLC.clinicalStatus in Common.&quot;Active Condition&quot;
    )
  else
    false"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="15"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Is Opioid Review Useful?"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Is Opioid Review Useful?&quot;:
  not &quot;Patient Age Less Than 18&quot;
    and not &quot;Condition Positive for Sickle Cell&quot;
    and not &quot;Conditions Indicating End Of Life Present&quot;
    and not &quot;Order For Palliative Care In Past 90 Days&quot;
    and not &quot;Is Active Cancer Treatment?&quot;
    and not &quot;Conditions Including Cancer To Exclude Opioid Management Indicating End-Stage Disease Present&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="16"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC11"/>
    </extension>
    <extension url="name">
      <valueString value="Inclusion Criteria"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Inclusion Criteria&quot;:
  (
    (
      &quot;Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential&quot;
        and exists Common.&quot;Active Ambulatory Benzodiazepine Rx&quot;
    )
      or (
        &quot;Patient Is Being Prescribed Benzodiazepine&quot;
          and exists Common.&quot;Active Ambulatory Opioid Rx&quot;
      )
  )
    and Routines.&quot;Is Opioid Review Useful?&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="17"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Conditions Indicating End of Life or With Limited Life Expectancy"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Conditions Indicating End of Life or With Limited Life Expectancy&quot;:
  (
    &quot;US Core-Categorized Conditions&quot; C
      where C.code in &quot;Conditions likely terminal for opioid prescribing&quot;
        and C.clinicalStatus in &quot;Active Condition&quot;
  )
  union
  (
    &quot;US Core-Categorized Conditions&quot; C
      where C.code in &quot;Limited life expectancy conditions&quot;
        and C.clinicalStatus in &quot;Active Condition&quot;
  )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="18"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString value="Admitted/Referred/Discharged to Hospice Care"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Admitted/Referred/Discharged to Hospice Care&quot;:
  (
    [Procedure: code in &quot;Hospice Procedure Codes&quot;] P
      where P.status.value in { 'in-progress', 'completed' }
  )
  union
  (
    &quot;Service Requests&quot; SR
      where SR.code in &quot;Hospice Procedure Codes&quot;
        and SR.status.value in { 'active', 'completed' }
  )
  union
  (
    if (Config.&quot;Hospice Findings Exclusion Enabled&quot;) then
      [Observation: code in &quot;Hospice Finding Codes&quot;] O
        where not (O.status.value in { 'unknown', 'entered-in-error', 'cancelled' })
    else
      {}
  )
  union
  (
    [Encounter] E
      where date from E.period.start 1 year or less on or before Today()
        and (
          if E.hospitalization.dischargeDisposition.coding is null
              or not exists (E.hospitalization.dischargeDisposition.coding)
            then false
          else E.hospitalization.dischargeDisposition in &quot;Hospice Disposition&quot;
        )
        and E.status.value in { 'planned', 'arrived', 'in-progress', 'finished', 'onleave' }
  )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="19"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString value="End of Life Assessment"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;End of Life Assessment&quot;:
    // 1. Conditions indicating end of life or with limited life expectancy
    exists (
      &quot;Conditions Indicating End of Life or With Limited Life Expectancy&quot;
    )
    // 2. Admitted/referred/discharged to hospice care
    or exists (
      &quot;Admitted/Referred/Discharged to Hospice Care&quot;
    )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="20"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC11"/>
    </extension>
    <extension url="name">
      <valueString value="Exclusion Criteria"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Exclusion Criteria&quot;:
  Common.&quot;End of Life Assessment&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="21"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC11"/>
    </extension>
    <extension url="name">
      <valueString value="Is Recommendation Applicable?"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Is Recommendation Applicable?&quot;:
  &quot;Inclusion Criteria&quot;
    and not &quot;Exclusion Criteria&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="22"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC11"/>
    </extension>
    <extension url="name">
      <valueString value="Get Detail"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Get Detail&quot;:
  if &quot;Is Recommendation Applicable?&quot;
    then
      'Consider whether the benefits outweigh the risks of concurrently prescribing opioids and benzodiazepines, or other central nervous system depressant medications.

When co-prescribing risks outweigh benefits, consult the [2022 CDC Clinical Practice Guideline Recommendation 11](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=evidence%20type%3A%203).-,Implementation%20Considerations,-Although%20in%20some) for further guidance.

[For patients being treated for opioid use disorder who are also taking benzodiazepines or other medications that depress the central nervous system, the CDC recommends not withholding buprenorphine or methadone](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=gabapentin%20and%20pregabalin).-,Buprenorphine%20or%20methadone%20for%20opioid%20use%20disorder%20should%20not%20be%20withheld%20from%20patients%20taking%20benzodiazepines%20or%20other%20medications%20that%20depress%20the%20central%20nervous%20system.,-Clinicians%20should%20check).

If the decision is made to taper benzodiazepine medications, [the CDC recommends tapering benzodiazepines gradually prior to discontinuation](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=Clinicians%20should%20taper%20benzodiazepines%20gradually%20before%20discontinuation%20because%20abrupt%20withdrawal%20can%20be%20associated%20with%20rebound%20anxiety%2C%20hallucinations%2C%20seizures%2C%20delirium%20tremens%2C%20and%2C%20rarely%2C%20death.%20The%20rate%20of%20tapering%20should%20be%20individualized).'
  else null"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="23"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/cqfm-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC11"/>
    </extension>
    <extension url="name">
      <valueString value="Get Indicator"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Get Indicator&quot;:
  if &quot;Is Recommendation Applicable?&quot;
    then 'warning'
  else null"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="24"/>
    </extension>
  </extension>
  <extension
             url="http://fhir.org/guides/cdc/opioid-cds/StructureDefinition/effectiveDataRequirements" id="effective-data-requirements">
    <valueReference>
      <reference value="#effective-data-requirements"/>
    </valueReference>
  </extension>
  <url
       value="http://fhir.org/guides/cdc/opioid-cds/PlanDefinition/opioidcds-11"/>
  <identifier>
    <use value="official"/>
    <value value="cdc-opioid-guidance"/>
  </identifier>
  <version value="2022.1.0"/>
  <name value="CDC_opioid_11"/>
  <title
         value="PlanDefinition - 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain: Recommendation #11"/>
  <type>
    <coding>
      <system
              value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
      <code value="eca-rule"/>
      <display value="ECA Rule"/>
    </coding>
  </type>
  <status value="draft"/>
  <experimental value="true"/>
  <date value="2023-05-01"/>
  <publisher value="Centers for Disease Control and Prevention (CDC)"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="https://www.cdc.gov"/>
    </telecom>
  </contact>
  <description
               value="Concurrently prescribing opioid medications with benzodiazepines increases the risk of harm for the patient."/>
  <useContext>
    <code>
      <system
              value="http://terminology.hl7.org/CodeSystem/usage-context-type"/>
      <code value="focus"/>
      <display value="Clinical Focus"/>
    </code>
    <valueCodeableConcept>
      <coding>
        <system value="http://snomed.info/sct"/>
        <code value="182888003"/>
        <display value="Medication requested (situation)"/>
      </coding>
    </valueCodeableConcept>
  </useContext>
  <useContext>
    <code>
      <system
              value="http://terminology.hl7.org/CodeSystem/usage-context-type"/>
      <code value="focus"/>
      <display value="Clinical Focus"/>
    </code>
    <valueCodeableConcept>
      <coding>
        <system value="http://snomed.info/sct"/>
        <code value="82423001"/>
        <display value="Chronic pain (finding)"/>
      </coding>
    </valueCodeableConcept>
  </useContext>
  <purpose
           value="The 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain is intended to improve communication between providers and patients about the risks and benefits of opioid therapy for chronic pain, improve the safety and effectiveness of pain treatment, and reduce the risks associated with long-term opioid therapy, including opioid use disorder and overdose. The Guideline is not intended for patients who are in active cancer treatment, palliative care, or end-of-life care."/>
  <usage
         value="Clinicians should avoid prescribing opioid pain medication and benzodiazepines or other central nervous system depressant concurrently whenever possible."/>
  <copyright value="© CDC 2016+."/>
  <topic>
    <text value="Opioid Prescribing"/>
  </topic>
  <author>
    <name value="Kensaku Kawamoto, MD, PhD, MHS"/>
  </author>
  <author>
    <name value="Bryn Rhodes"/>
  </author>
  <author>
    <name value="Floyd Eisenberg, MD, MPH"/>
  </author>
  <author>
    <name value="Robert McClure, MD, MPH"/>
  </author>
  <relatedArtifact>
    <type value="documentation"/>
    <display
             value="2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain"/>
    <url value="https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm"/>
    <document>
      <url value="https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm"/>
    </document>
  </relatedArtifact>
  <relatedArtifact>
    <type value="documentation"/>
    <display value="MME Conversion Tables"/>
    <url
         value="https://www.cdc.gov/drugoverdose/pdf/calculating_total_daily_dose-a.pdf"/>
    <document>
      <url
           value="https://www.cdc.gov/drugoverdose/pdf/calculating_total_daily_dose-a.pdf"/>
    </document>
  </relatedArtifact>
  <library
           value="http://fhir.org/guides/cdc/opioid-cds/Library/OpioidCDSREC11"/>
  <action>
    <extension
               url="http://hl7.org/fhir/StructureDefinition/cqf-strengthOfRecommendation">
      <valueCodeableConcept>
        <coding>
          <system
                  value="http://terminology.hl7.org/CodeSystem/recommendation-strength"/>
          <code value="weak"/>
          <display value="Weak"/>
        </coding>
      </valueCodeableConcept>
    </extension>
    <extension
               url="http://hl7.org/fhir/StructureDefinition/cqf-qualityOfEvidence">
      <valueCodeableConcept>
        <coding>
          <system
                  value="http://terminology.hl7.org/CodeSystem/evidence-quality"/>
          <code value="low"/>
          <display value="Low quality"/>
        </coding>
      </valueCodeableConcept>
    </extension>
    <title
           value="Existing patient has concurrent opioid and benzodiazepine prescriptions."/>
    <description
                 value="Checking if the trigger prescription meets the inclusion criteria for recommendation #11 workflow."/>
    <trigger>
      <type value="named-event"/>
      <name value="order-select"/>
    </trigger>
    <condition>
      <kind value="applicability"/>
      <expression>
        <description
                     value="Check whether the existing patient is using opioids concurrently with benzodiazepines."/>
        <language value="text/cql.identifier"/>
        <expression value="Is Recommendation Applicable?"/>
      </expression>
    </condition>
    <groupingBehavior value="visual-group"/>
    <selectionBehavior value="any"/>
    <dynamicValue>
      <path value="action.description"/>
      <expression>
        <language value="text/cql.identifier"/>
        <expression value="Get Detail"/>
      </expression>
    </dynamicValue>
    <dynamicValue>
      <path value="action.title"/>
      <expression>
        <language value="text/cql.identifier"/>
        <expression value="Get Summary"/>
      </expression>
    </dynamicValue>
    <dynamicValue>
      <path value="action.extension"/>
      <expression>
        <language value="text/cql.identifier"/>
        <expression value="Get Indicator"/>
      </expression>
    </dynamicValue>
    <action>
      <description value="Document - Will modify prescription"/>
    </action>
    <action>
      <description
                   value="Snooze* - Benefits outweigh risks, snooze 3 months"/>
    </action>
    <action>
      <description value="Snooze* - N/A see comment, snooze 3 months"/>
    </action>
  </action>
</PlanDefinition>