2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide
2022.1.0 - CI Build

2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide, published by Centers for Disease Control and Prevention (CDC). This guide is not an authorized publication; it is the continuous build for version 2022.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/cqframework/opioid-cds-r4/ and changes regularly. See the Directory of published versions

: Recommendation #9 - Consider Patient's History of Controlled Substance Prescriptions - XML Representation

Draft as of 2025-08-06

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<PlanDefinition xmlns="http://hl7.org/fhir">
  <id value="opioidcds-09"/>
  <meta>
    <profile
             value="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-recommendationdefinition"/>
    <profile
             value="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-publishableplandefinition"/>
  </meta>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
    <table class="grid dict">
        
        <tr>
            <th scope="row"><b>Id: </b></th>
            <td style="padding-left: 4px;">opioidcds-09</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Url: </b></th>
            <td style="padding-left: 4px;"><a href="PlanDefinition-opioidcds-09.html">Recommendation #9 - Consider Patient's History of Controlled Substance Prescriptions</a></td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Version: </b></th>
            <td style="padding-left: 4px;">2022.1.0</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Identifier: </b></th>
            <td style="padding-left: 4px;">
                
                
                <p style="margin-bottom: 5px;">
                    <b>value: </b> <span>cdc-opioid-guidance</span>
                </p>
                
            </td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Name: </b></th>
            <td style="padding-left: 4px;">PlanDefinition_Recommendation_09_Order_Sign</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Title: </b></th>
            <td style="padding-left: 4px;">Recommendation #9 - Consider Patient's History of Controlled Substance Prescriptions</td>
        </tr>
        
        
        
        <tr>
            <th scope="row"><b>Status: </b></th>
            <td style="padding-left: 4px;">draft</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Experimental: </b></th>
            <td style="padding-left: 4px;">true</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Type: </b></th>
            <td style="padding-left: 4px;">
                
                    
                        
                        <p style="margin-bottom: 5px;">
                            <b>system: </b> <span><a href="http://terminology.hl7.org/6.5.0/CodeSystem-plan-definition-type.html">http://terminology.hl7.org/CodeSystem/plan-definition-type</a></span>
                        </p>
                        
                        
                        <p style="margin-bottom: 5px;">
                            <b>code: </b> <span>eca-rule</span>
                        </p>
                        
                        
                        <p style="margin-bottom: 5px;">
                            <b>display: </b> <span>ECA Rule</span>
                        </p>
                        
                    
                
                
            </td>
        </tr>
        
        
        
        <tr>
            <th scope="row"><b>Date: </b></th>
            <td style="padding-left: 4px;">2025-08-06</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Publisher: </b></th>
            <td style="padding-left: 4px;">Centers for Disease Control and Prevention (CDC)</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Description: </b></th>
            <td style="padding-left: 4px;">When prescribing initial opioid therapy for acute, subacute, or chronic pain, and periodically during opioid therapy for chronic pain, clinicians should review the patient's history of controlled substance prescriptions using state prescription drug monitoring program (PDMP) data to determine whether the patient is receiving opioid dosages or combinations that put the patient at high risk for overdose.</td>
        </tr>
        
        
            <tr>
                <th scope="row"><a name="effective-data-requirements"> </a><b>Logic Definitions: </b></th>
                <td style="padding-left: 4px;">
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC09</td>
                                
                                
                                    <td>Chronic Pain Opioid Analgesic with Ambulatory Misuse Potential Prescriptions</td>
                                
                                
                                    <td>0</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Chronic Pain Opioid Analgesic with Ambulatory Misuse Potential Prescriptions&quot;:
  ( Common.&quot;Is Opioid Analgesic with Ambulatory Misuse Potential?&quot;( ContextPrescriptions ) ) AmbulatoryOpioidPrescription
    where Routines.&quot;Is Subacute or Chronic Pain Prescription?&quot;( AmbulatoryOpioidPrescription )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC09</td>
                                
                                
                                    <td>Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential</td>
                                
                                
                                    <td>1</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential&quot;:
  exists( &quot;Chronic Pain Opioid Analgesic with Ambulatory Misuse Potential Prescriptions&quot; )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommonConfig</td>
                                
                                
                                    <td>Age Less than 18 Years Is Enabled</td>
                                
                                
                                    <td>2</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// CDC 2022 General Inclusion Criteria
define &quot;Age Less than 18 Years Is Enabled&quot;:
  true</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Patient Age Less Than 18</td>
                                
                                
                                    <td>3</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Patient Age Less Than 18&quot;:
  if (Config.&quot;Age Less than 18 Years Is Enabled&quot;) then
    AgeInYearsAt(Today()) &lt; 18
  else false</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommonConfig</td>
                                
                                
                                    <td>Sickle Cell Check Enabled</td>
                                
                                
                                    <td>4</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// Sickle Cell
define &quot;Sickle Cell Check Enabled&quot;:
  true</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommonConfig</td>
                                
                                
                                    <td>Sickle Cell Assumed Active</td>
                                
                                
                                    <td>5</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Sickle Cell Assumed Active&quot;:
  true</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>US Core-Categorized Conditions</td>
                                
                                
                                    <td>6</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// 3. Medications indicating end of life
    /* or exists (
      &quot;Medications Indicating End of Life&quot;
    ) */

define &quot;US Core-Categorized Conditions&quot;:
  [Condition: category in &quot;Encounter Diagnosis Condition Category&quot;]
    union [Condition: category in &quot;Problem List Condition Category&quot;]
    union [Condition: category in &quot;US Core Health Concern Condition Category&quot;]</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>Positive Sickle Cell Condition</td>
                                
                                
                                    <td>7</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Positive Sickle Cell Condition&quot;:
  if Config.&quot;Sickle Cell Check Enabled&quot; and not Config.&quot;Sickle Cell Assumed Active&quot;
    then (
      &quot;US Core-Categorized Conditions&quot; C
        where C.code in &quot;Sickle Cell Diseases&quot;
          and C.clinicalStatus in &quot;Active Condition&quot;
    ) else if Config.&quot;Sickle Cell Check Enabled&quot; and Config.&quot;Sickle Cell Assumed Active&quot;
        then (
          &quot;US Core-Categorized Conditions&quot; C
            where C.code in &quot;Sickle Cell Diseases&quot;
        )
      else null</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Condition Positive for Sickle Cell</td>
                                
                                
                                    <td>8</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Condition Positive for Sickle Cell&quot;:
  if (Config.&quot;Sickle Cell Check Enabled&quot;) then
    exists(
      Common.&quot;Positive Sickle Cell Condition&quot;
    ) 
  else false</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommonConfig</td>
                                
                                
                                    <td>Active Cancer Treatment Encounters Condition Is Enabled</td>
                                
                                
                                    <td>9</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// Active Cancer Treatment
define &quot;Active Cancer Treatment Encounters Condition Is Enabled&quot;:
  true</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Encounter Period</td>
                                
                                
                                    <td>10</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// End of Opioid Naive Routine

/*
**  Routine #3
**  Active Cancer Treatment Routine
**
**  Definition                    | Answer to Proceed   | Details                                    | Data (Terminology) Requirement
**  ---------------------------------------------------------------------------------------------------------------------------------
**  Two office visits within the  | No                  | Look for a minimum of two distinct         | Office Visit
**  past 12 months                |                     | encounters within 12 months of the date    |
**                                |                     | of the current visit for which each of the |
**                                |                     | following is true:                         |
**                                |                     |   - the encounter diagnosis (primary or    |
**                                |                     |     secondary or co-morbidity diagnosis)   |
**                                |                     |     is listed in the CDC Malignant Cancer  |
**                                |                     |     Conditions value set                   |
**  ---------------------------------------------------------------------------------------------------------------------------------
**  Office visits with an         | No                  | The encounter is performed by an           | Oncology specialty
**  oncology specialist           |                     | oncologist as defined in the oncology      | designations (NUCC)
**  present                       |                     | specialty designations using the           |
**                                |                     | National Uniform Claim Committee           |
**                                |                     | (NUCC) classifications                     |
**  ---------------------------------------------------------------------------------------------------------------------------------
**  Office visits including CDC   | No                  | The encounter diagnosis (primary or        | CDC malignant cancer
**  malignant cancer              |                     | secondary or co-morbidity diagnosis)       | conditions
**  condition                     |                     | is listed in the CDC Malignant Cancer      |
**                                |                     | Conditions value set                       |
**  ----------------------------------------------------------------------------------------------------------------------------------
**
*/

define &quot;Encounter Period&quot;:
  Interval[Today() - 12 months, Today())</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>USCore Encounter Cancer Diagnoses</td>
                                
                                
                                    <td>11</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;USCore Encounter Cancer Diagnoses&quot;:
  [Condition: category in &quot;Encounter Diagnosis Condition Category&quot;] CancerDiagnoses
    where CancerDiagnoses.code in &quot;CDC malignant cancer conditions&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Encounters with Cancer Diagnosis During Encounter Period</td>
                                
                                
                                    <td>12</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// encounter-diagnosis, problem-list and health-concern Conditions
// define &quot;US Core-Categorized Cancer Diagnoses&quot;:
//   Common.&quot;US Core-Categorized Conditions&quot; C
//     where C.code in Common.&quot;CDC malignant cancer conditions&quot;

// define &quot;Encounters with Cancer Diagnosis During Encounter Period&quot;:
//   [Encounter] Encounter
//     with &quot;US Core-Categorized Cancer Diagnoses&quot; CancerDiagnosis
//     such that date from Encounter.period.&quot;start&quot;.value in day of &quot;Encounter Period&quot;
//       and EndsWith(CancerDiagnosis.encounter.reference, Encounter.id)

define &quot;Encounters with Cancer Diagnosis During Encounter Period&quot;:
  [Encounter] Encounters
    where date from Encounters.period.&quot;start&quot; in day of &quot;Encounter Period&quot;
      and exists (
        Common.&quot;USCore Encounter Cancer Diagnoses&quot; CancerDiagnoses
          where EndsWith(CancerDiagnoses.encounter.reference, Encounters.id)
      )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Number of Encounters with Cancer Diagnosis During Encounter Period</td>
                                
                                
                                    <td>13</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Number of Encounters with Cancer Diagnosis During Encounter Period&quot;:
  Count (&quot;Encounters with Cancer Diagnosis During Encounter Period&quot;)</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Has Two or More Encounters with Cancer Diagnosis During Encounter Period</td>
                                
                                
                                    <td>14</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Has Two or More Encounters with Cancer Diagnosis During Encounter Period&quot;:
  &quot;Number of Encounters with Cancer Diagnosis During Encounter Period&quot; &gt;= 2</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>USCore Problem List Cancer Diagnoses</td>
                                
                                
                                    <td>15</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;USCore Problem List Cancer Diagnoses&quot;:
  [Condition: category in &quot;Problem List Condition Category&quot;] CancerDiagnoses
    where CancerDiagnoses.code in &quot;CDC malignant cancer conditions&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Has Active Cancer Diagnosis on Problem List</td>
                                
                                
                                    <td>16</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Has Active Cancer Diagnosis on Problem List&quot;:
  exists (
    Common.&quot;USCore Problem List Cancer Diagnoses&quot; CancerDiagnoses
      where CancerDiagnoses.category in Common.&quot;Problem List Condition Category&quot;
        and exists(
          CancerDiagnoses.clinicalStatus.coding ClinicalStatus
            where ClinicalStatus.code ~ 'active'
        )
  )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Is Active Cancer Treatment?</td>
                                
                                
                                    <td>17</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Is Active Cancer Treatment?&quot;:
  if (Config.&quot;Active Cancer Treatment Encounters Condition Is Enabled&quot;) 
    then &quot;Has Two or More Encounters with Cancer Diagnosis During Encounter Period&quot;
      or &quot;Has Active Cancer Diagnosis on Problem List&quot;
  else false</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommonConfig</td>
                                
                                
                                    <td>End-Stage Disease Criteria Enabled</td>
                                
                                
                                    <td>18</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// CDC 2022 General Inclusion Criteria
define &quot;End-Stage Disease Criteria Enabled&quot;:
  true</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Conditions Likely Terminal for Opioid Prescribing</td>
                                
                                
                                    <td>19</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Conditions Likely Terminal for Opioid Prescribing&quot;:
  if (Config.&quot;End-Stage Disease Criteria Enabled&quot;) then
    exists (
      Common.&quot;US Core-Categorized Conditions&quot; EOLC
        where EOLC.code in Common.&quot;Conditions likely terminal for opioid prescribing&quot;
          // and EOLC.clinicalStatus in Common.&quot;Active Condition&quot;
    )
  else false</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>CDC 2022 Guideline General Inclusion Criteria</td>
                                
                                
                                    <td>20</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;CDC 2022 Guideline General Inclusion Criteria&quot;:
  not &quot;Patient Age Less Than 18&quot;
    and not &quot;Condition Positive for Sickle Cell&quot;
    and not &quot;Is Active Cancer Treatment?&quot;
    and not &quot;Conditions Likely Terminal for Opioid Prescribing&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommonConfig</td>
                                
                                
                                    <td>PDMP Data Not Reviewed in Past 90 Days Criteria Enabled</td>
                                
                                
                                    <td>21</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// Recommendation 9
define &quot;PDMP Data Not Reviewed in Past 90 Days Criteria Enabled&quot;:
  true</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC09</td>
                                
                                
                                    <td>Look Back 90 Days</td>
                                
                                
                                    <td>22</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Look Back 90 Days&quot;:
  Interval[Today() - 90 days, Today()]</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC09</td>
                                
                                
                                    <td>PDMP Data Not Reviewed in Past 90 Days</td>
                                
                                
                                    <td>23</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;PDMP Data Not Reviewed in Past 90 Days&quot;:
  Config.&quot;PDMP Data Not Reviewed in Past 90 Days Criteria Enabled&quot;
    and not (
      exists (
        [Procedure: Common.&quot;PDMP review procedure&quot;] P
          where P.status ~ 'completed'
            and P.performed during &quot;Look Back 90 Days&quot;
      )
      or exists (
        [Observation: Common.&quot;PDMP data reviewed finding&quot;] O
          where O.status in { 'final', 'amended' }
            and (
              if O.effective is FHIR.Period
                then (O.effective as FHIR.Period) during day of &quot;Look Back 90 Days&quot;
                else if O.effective is FHIR.dateTime
                  then date from O.effective in day of &quot;Look Back 90 Days&quot;
                  else false
          )
      )
    )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC09</td>
                                
                                
                                    <td>Inclusion Criteria</td>
                                
                                
                                    <td>24</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Inclusion Criteria&quot;:
  &quot;Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential&quot;
    and Routines.&quot;CDC 2022 Guideline General Inclusion Criteria&quot;
    and &quot;PDMP Data Not Reviewed in Past 90 Days&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC09</td>
                                
                                
                                    <td>Exclusion Criteria</td>
                                
                                
                                    <td>25</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Exclusion Criteria&quot;:
  false</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSREC09</td>
                                
                                
                                    <td>Is Recommendation Applicable?</td>
                                
                                
                                    <td>26</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define &quot;Is Recommendation Applicable?&quot;:
  &quot;Inclusion Criteria&quot;
    and not &quot;Exclusion Criteria&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>Is Opioid Analgesic with Ambulatory Misuse Potential?</td>
                                
                                
                                    <td>27</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function &quot;Is Opioid Analgesic with Ambulatory Misuse Potential?&quot;(value List&lt;MedicationRequest&gt;):
  (&quot;Get MedicationRequest Medication as Code&quot;(value)) Rx
    where Rx.medication in &quot;Opioid analgesics with ambulatory misuse potential&quot; 
      and Rx.category in &quot;Community&quot;</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>Get MedicationRequest Medication as Code</td>
                                
                                
                                    <td>28</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function &quot;Get MedicationRequest Medication as Code&quot;(value List&lt;MedicationRequest&gt;):
  value Rx
    let Med: 
      if Rx.medication is Reference then singleton from (
        [Medication] M
          where M.id = (Last(Split((Rx.medication as FHIR.Reference).reference, '/')))
      ) else null
    return 
      MedicationRequest {
        id: Rx.id,
        status: Rx.status,
        intent: Rx.intent,
        category: Rx.category,
        medication: if Rx.medication is Reference then Med.code else Rx.medication as CodeableConcept,
        subject: Rx.subject,
        authoredOn: Rx.authoredOn,
        recorder: Rx.recorder,
        dosageInstruction: Rx.dosageInstruction,
        dispenseRequest: Rx.dispenseRequest
      }</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>FHIRHelpers</td>
                                
                                
                                    <td>ToString</td>
                                
                                
                                    <td>29</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function ToString(value string): value.value</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>FHIRHelpers</td>
                                
                                
                                    <td>ToConcept</td>
                                
                                
                                    <td>30</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function ToConcept(concept FHIR.CodeableConcept):
    if concept is null then
        null
    else
        System.Concept {
            codes: concept.coding C return ToCode(C),
            display: concept.text.value
        }</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>FHIRHelpers</td>
                                
                                
                                    <td>ToCode</td>
                                
                                
                                    <td>31</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function ToCode(coding FHIR.Coding):
    if coding is null then
        null
    else
        System.Code {
          code: coding.code.value,
          system: coding.system.value,
          version: coding.version.value,
          display: coding.display.value
        }</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Is Subacute or Chronic Pain Prescription?</td>
                                
                                
                                    <td>32</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">// End of Active Cancer Treatment Routine

/*
**  Routine #4
**  For Subacute or Chronic Pain Routine
**
**  Definition                  | Answer to Proceed   | Details                                        | Data (Terminology) Requirement
**  -----------------------------------------------------------------------------------------------------------------------------------
**  Order for opioid analgesic  | Yes                 | Order for opioid analgesics with ambulatory    | Opioid analgesics with
**  with expected supply        |                     | misuse potential with a supply duration of &gt;=  | ambulatory misuse potential
**  duration &gt;= 28 days         |                     | 28 days                                        |
**                              |                     |                                                |
**                              |                     | - Subacute definition = order for opioid       |
**                              |                     |   analgesics with ambulatory misuse            |
**                              |                     |   potential with a supply duration of one to   |
**                              |                     |   two months.                                  |
**                              |                     | - Chronic pain definition = order for opioid   |
**                              |                     |   analgesics with ambulatory misuse            |
**                              |                     |   potential with a supply duration of &gt;= two   |
**                              |                     |   months.                                      |
**  -----------------------------------------------------------------------------------------------------------------------------------
**
*/

define function &quot;Is Subacute or Chronic Pain Prescription?&quot;(prescription FHIR.MedicationRequest):
  &quot;Is Subacute or Chronic Pain Using Expected Supply Duration&quot;(prescription)
    or &quot;Is Subacute or Chronic Pain Using Validity Period&quot;(prescription)</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Is Subacute or Chronic Pain Using Expected Supply Duration</td>
                                
                                
                                    <td>33</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function &quot;Is Subacute or Chronic Pain Using Expected Supply Duration&quot;(prescription FHIR.MedicationRequest):
  (
    prescription.dispenseRequest is not null
      and prescription.dispenseRequest.expectedSupplyDuration is not null
      and (
        Common.GetDurationInDays(prescription.dispenseRequest.expectedSupplyDuration) &gt;= 28 days 
      )
  )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSCommon</td>
                                
                                
                                    <td>GetDurationInDays</td>
                                
                                
                                    <td>34</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function GetDurationInDays(value FHIR.Duration):
  if value is null then null
  else
    case
      when value.code.value ~ 'a' then System.Quantity{ value: value.value.value * 365.0, unit: 'days' }
      when value.code.value ~ 'mo' then System.Quantity{ value: value.value.value * 30.0, unit: 'days' }
      when value.code.value ~ 'wk' then System.Quantity{ value: value.value.value * 7.0, unit: 'days' }
      when value.code.value ~ 'd' then System.Quantity{ value: value.value.value, unit: 'days' }
      when value.code.value ~ 'h' then System.Quantity{ value: value.value.value / 24.0, unit: 'days' }
      when value.code.value ~ 'min' then System.Quantity{ value: value.value.value / 60.0 / 24.0, unit: 'days' }
      when value.code.value ~ 's' then System.Quantity{ value: value.value.value / 60.0 / 60.0 / 24.0, unit: 'days' }
      when value.code.value ~ 'ms' then System.Quantity{ value: value.value.value / 60.0 / 60.0 / 24.0 / 1000.0, unit: 'days' }
      when value.code.value is null then Message(1000, true, 'Undefined', 'Error', 'Duration unit code is null')
      else Message(1000, true, 'Undefined', 'Error', 'Unsupported duration unit code: ' + value.code.value)
end</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>OpioidCDSRoutines</td>
                                
                                
                                    <td>Is Subacute or Chronic Pain Using Validity Period</td>
                                
                                
                                    <td>35</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function &quot;Is Subacute or Chronic Pain Using Validity Period&quot;(prescription FHIR.MedicationRequest):
  (
    prescription.dispenseRequest is not null
      and prescription.dispenseRequest.validityPeriod is not null
      and (
        days between prescription.dispenseRequest.validityPeriod.start and prescription.dispenseRequest.validityPeriod.end &gt;= 28 
      )
  )</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>FHIRHelpers</td>
                                
                                
                                    <td>ToDateTime</td>
                                
                                
                                    <td>36</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function ToDateTime(value dateTime): value.value</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>FHIRHelpers</td>
                                
                                
                                    <td>ToString</td>
                                
                                
                                    <td>37</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function ToString(value ProcedureStatus): value.value</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>FHIRHelpers</td>
                                
                                
                                    <td>ToInterval</td>
                                
                                
                                    <td>38</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function ToInterval(period FHIR.Period):
    if period is null then
        null
    else
        if period.&quot;start&quot; is null then
            Interval(period.&quot;start&quot;.value, period.&quot;end&quot;.value]
        else
            Interval[period.&quot;start&quot;.value, period.&quot;end&quot;.value]</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>FHIRHelpers</td>
                                
                                
                                    <td>ToString</td>
                                
                                
                                    <td>39</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function ToString(value ObservationStatus): value.value</code></pre>
                        
                        <br/><br/>
                    
                        <table class="grid-dict">
                            <tr><th><b>Library Name</b></th><th><b>Name</b></th><th><b>sequence</b></th></tr>
                            <tr>
                                
                                    <td>FHIRHelpers</td>
                                
                                
                                    <td>ToDateTime</td>
                                
                                
                                    <td>40</td>
                                
                            </tr>
                        </table>
                        
                            <pre style="max-width: 990px;"><code class="language-cql">define function ToDateTime(value instant): value.value</code></pre>
                        
                        <br/><br/>
                    
                </td>
            </tr>
        
        
        <tr>
          <th scope="row"><b>Knowledge Capability: </b></th>
          <td style="padding-left: 4px;">
            shareable computable executable publishable 
          </td>
        </tr>
        
        
        
        <tr>
            <th scope="row"><b>Use Context: </b></th>
            <td style="padding-left: 4px;">
                <table class="grid-dict">
                    <tr><th><b>code</b></th><th><b>value</b></th><th><b>display</b></th></tr>
                    
                      <tr>
                        <td>focus</td>
                        <td>182888003</td>
                        <td>Medication requested (situation)</td>
                      </tr>
                    
                      <tr>
                        <td>focus</td>
                        <td>82423001</td>
                        <td>Chronic pain (finding)</td>
                      </tr>
                    
                      <tr>
                        <td>focus</td>
                        <td>274663001</td>
                        <td>Acute pain (finding)</td>
                      </tr>
                    
                      <tr>
                        <td>focus</td>
                        <td/>
                        <td/>
                      </tr>
                    
                </table>
            </td>
        </tr>
        
        
        
        <tr>
            <th scope="row"><b>Purpose: </b></th>
            <td style="padding-left: 4px;"><div><p>The 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain is intended to improve communication between clinicians and patients about the benefits and risks of pain treatments, including opioid therapy; improve the effectiveness and safety of pain treatment; mitigate pain; improve function and quality of life for patients with pain; and reduce risks associated with opioid pain therapy, including opioid use disorder, overdose, and death. The recommendations do not apply to pain related to sickle cell disease or cancer or to patients receiving palliative or end-of-life care.</p>
</div></td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Usage: </b></th>
            <td style="padding-left: 4px;">At a minimum, during long-term opioid therapy, PDMP data should be reviewed before an initial opioid prescription and then every 3 months or more frequently.</td>
        </tr>
        
        
        <tr>
            <th scope="row"><b>Copyright: </b></th>
            <td style="padding-left: 4px;"><div><p>© CDC 2016+.</p>
</div></td>
        </tr>
        
        
        
        
        
        
        <tr>
          <th scope="row"><b>Related Artifacts: </b></th>
          <td style="padding-left: 4px;">
            
            <p><b>Documentation</b></p>
            <ul>
              
                  <li>
                    <a href="https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm"> 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain</a>
                  </li>
              
            </ul>
            
            
            
            
            
            
            
          </td>
        </tr>
        

        
        <tr>
          <th scope="row"><b>Libraries: </b></th>
          <td style="padding-left: 4px;">
            <table class="grid-dict">
              
                <tr><td><a href="Library-OpioidCDSREC09.html">Library - Recommendation #9 - Consider Patient's History of Controlled Substance Prescriptions</a></td></tr>
              
            </table>
          </td>
        </tr>
        

        
        <tr>
          <th scope="row"><b>Actions: </b></th>
          <td style="padding-left: 4px;">
            <table class="grid-dict">
              
                <tr>
                  <td>
                    <b> Before Ordering Opioids, Review PDMP Data:</b> Review PDMP data for this patient before completing an opioid order.

For guidance about utilizing PDMP information to improve patient safety, see [Recommendation 9 of the 2022 CDC Clinical Practice Guideline](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=Clinicians%20should%20take,see%20Recommendation%2010).).

[CDC advises not to dismiss patients from your practice on the basis of PDMP information](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=Clinicians%20should%20not%20dismiss,Recommendations%208%20and%2012%5D).)<br/>
                    <b>When:</b> <i>Named Event:</i> order-sign<br/>
                    <b>If:</b> <i>Applicability:</i> Check whether the current order is for an opioid with ambulatory misuse potential, if the 2022 CDC guideline general inclusion criteria is met or there exists evidence of a prescription drug monitoring program (PDMP) review procedure or finding occurred in the past 90 days. <i>(Is Recommendation Applicable?)</i><br/>
                    <b>Then:</b>
                    
                      <table class="grid-dict">
                        
                          <tr>
                            <td>
                              <b> :</b> Access Data - Launch app to review PDMP data<br/>
                              
                              
                              <b>Then:</b>
                              
                                
                                
                              
                            </td>
                          </tr>
                        
                          <tr>
                            <td>
                              <b> :</b> Document - PDMP data reviewed, snooze 3 months<br/>
                              
                              
                              <b>Then:</b>
                              
                                
                                
                              
                            </td>
                          </tr>
                        
                          <tr>
                            <td>
                              <b> :</b> Snooze* - N/A see comment, snooze 3 months<br/>
                              
                              
                              <b>Then:</b>
                              
                                
                                
                              
                            </td>
                          </tr>
                        
                      </table>
                    
                  </td>
                </tr>
              
            </table>
          </td>
        </tr>
        
    </table>
</div>
  </text>
  <contained>
    <Library>
      <id value="effective-data-requirements"/>
      <name value="EffectiveDataRequirements"/>
      <status value="active"/>
      <type>
        <coding>
          <system value="http://terminology.hl7.org/CodeSystem/library-type"/>
          <code value="module-definition"/>
        </coding>
      </type>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Common"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/Library/OpioidCDSCommon|2022.1.0"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library FHIRHelpers"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/Library/FHIRHelpers|4.0.1"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Routines"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/Library/OpioidCDSRoutines|2022.1.0"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Config"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/Library/OpioidCDSCommonConfig|2022.1.0"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display
                 value="Value set Opioid analgesics with ambulatory misuse potential"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/opioid-analgesics-with-ambulatory-misuse-potential"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set Community"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/medicationrequest-category-community"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set Encounter Diagnosis Condition Category"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/condition-encounter-diagnosis-category"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set Problem List Condition Category"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/condition-problem-list-category"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set US Core Health Concern Condition Category"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/condition-us-core-health-concern-category"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set Sickle Cell Diseases"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/sickle-cell-diseases"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set Active Condition"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/condition-clinical-status-active"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set CDC malignant cancer conditions"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/cdc-malignant-cancer-conditions"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display
                 value="Value set Conditions likely terminal for opioid prescribing"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/conditions-likely-terminal-for-opioid-prescribing"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set PDMP review procedure"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/pdmp-review-procedure"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set PDMP data reviewed finding"/>
        <resource
                  value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/pdmp-data-reviewed-finding"/>
      </relatedArtifact>
      <parameter>
        <name value="ContextPrescriptions"/>
        <use value="in"/>
        <min value="0"/>
        <max value="*"/>
        <type value="MedicationRequest"/>
      </parameter>
      <parameter>
        <name value="Is Recommendation Applicable?"/>
        <use value="out"/>
        <min value="0"/>
        <max value="1"/>
        <type value="boolean"/>
      </parameter>
      <dataRequirement>
        <type value="Medication"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Medication"/>
        <mustSupport value="id"/>
        <mustSupport value="code"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Patient"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Patient"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Condition"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Condition"/>
        <mustSupport value="category"/>
        <mustSupport value="code"/>
        <mustSupport value="clinicalStatus"/>
        <codeFilter>
          <path value="category"/>
          <valueSet
                    value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/condition-us-core-health-concern-category"/>
        </codeFilter>
      </dataRequirement>
      <dataRequirement>
        <type value="Condition"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Condition"/>
        <mustSupport value="category"/>
        <mustSupport value="code"/>
        <mustSupport value="clinicalStatus"/>
        <mustSupport value="encounter"/>
        <mustSupport value="encounter.reference"/>
        <codeFilter>
          <path value="category"/>
          <valueSet
                    value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/condition-encounter-diagnosis-category"/>
        </codeFilter>
      </dataRequirement>
      <dataRequirement>
        <type value="Condition"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Condition"/>
        <mustSupport value="category"/>
        <mustSupport value="code"/>
        <mustSupport value="clinicalStatus"/>
        <mustSupport value="clinicalStatus.coding"/>
        <codeFilter>
          <path value="category"/>
          <valueSet
                    value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/condition-problem-list-category"/>
        </codeFilter>
      </dataRequirement>
      <dataRequirement>
        <type value="Encounter"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Encounter"/>
        <mustSupport value="period"/>
        <mustSupport value="period.start"/>
        <mustSupport value="id"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Procedure"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Procedure"/>
        <mustSupport value="code"/>
        <mustSupport value="status"/>
        <mustSupport value="performed"/>
        <codeFilter>
          <path value="code"/>
          <valueSet
                    value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/pdmp-review-procedure"/>
        </codeFilter>
      </dataRequirement>
      <dataRequirement>
        <type value="Observation"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Observation"/>
        <mustSupport value="code"/>
        <mustSupport value="status"/>
        <mustSupport value="effective"/>
        <codeFilter>
          <path value="code"/>
          <valueSet
                    value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/pdmp-data-reviewed-finding"/>
        </codeFilter>
      </dataRequirement>
    </Library>
  </contained>
  <extension
             url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
    <valueCode value="shareable"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
    <valueCode value="computable"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
    <valueCode value="executable"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
    <valueCode value="publishable"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC09"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Chronic Pain Opioid Analgesic with Ambulatory Misuse Potential Prescriptions"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Chronic Pain Opioid Analgesic with Ambulatory Misuse Potential Prescriptions&quot;:
  ( Common.&quot;Is Opioid Analgesic with Ambulatory Misuse Potential?&quot;( ContextPrescriptions ) ) AmbulatoryOpioidPrescription
    where Routines.&quot;Is Subacute or Chronic Pain Prescription?&quot;( AmbulatoryOpioidPrescription )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="0"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC09"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential&quot;:
  exists( &quot;Chronic Pain Opioid Analgesic with Ambulatory Misuse Potential Prescriptions&quot; )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="1"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommonConfig"/>
    </extension>
    <extension url="name">
      <valueString value="Age Less than 18 Years Is Enabled"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="// CDC 2022 General Inclusion Criteria
define &quot;Age Less than 18 Years Is Enabled&quot;:
  true"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="2"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Patient Age Less Than 18"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Patient Age Less Than 18&quot;:
  if (Config.&quot;Age Less than 18 Years Is Enabled&quot;) then
    AgeInYearsAt(Today()) &lt; 18
  else false"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="3"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommonConfig"/>
    </extension>
    <extension url="name">
      <valueString value="Sickle Cell Check Enabled"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="// Sickle Cell
define &quot;Sickle Cell Check Enabled&quot;:
  true"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="4"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommonConfig"/>
    </extension>
    <extension url="name">
      <valueString value="Sickle Cell Assumed Active"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Sickle Cell Assumed Active&quot;:
  true"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="5"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString value="US Core-Categorized Conditions"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="// 3. Medications indicating end of life
    /* or exists (
      &quot;Medications Indicating End of Life&quot;
    ) */

define &quot;US Core-Categorized Conditions&quot;:
  [Condition: category in &quot;Encounter Diagnosis Condition Category&quot;]
    union [Condition: category in &quot;Problem List Condition Category&quot;]
    union [Condition: category in &quot;US Core Health Concern Condition Category&quot;]"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="6"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString value="Positive Sickle Cell Condition"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Positive Sickle Cell Condition&quot;:
  if Config.&quot;Sickle Cell Check Enabled&quot; and not Config.&quot;Sickle Cell Assumed Active&quot;
    then (
      &quot;US Core-Categorized Conditions&quot; C
        where C.code in &quot;Sickle Cell Diseases&quot;
          and C.clinicalStatus in &quot;Active Condition&quot;
    ) else if Config.&quot;Sickle Cell Check Enabled&quot; and Config.&quot;Sickle Cell Assumed Active&quot;
        then (
          &quot;US Core-Categorized Conditions&quot; C
            where C.code in &quot;Sickle Cell Diseases&quot;
        )
      else null"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="7"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Condition Positive for Sickle Cell"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Condition Positive for Sickle Cell&quot;:
  if (Config.&quot;Sickle Cell Check Enabled&quot;) then
    exists(
      Common.&quot;Positive Sickle Cell Condition&quot;
    ) 
  else false"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="8"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommonConfig"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Active Cancer Treatment Encounters Condition Is Enabled"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="// Active Cancer Treatment
define &quot;Active Cancer Treatment Encounters Condition Is Enabled&quot;:
  true"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="9"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Encounter Period"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="// End of Opioid Naive Routine

/*
**  Routine #3
**  Active Cancer Treatment Routine
**
**  Definition                    | Answer to Proceed   | Details                                    | Data (Terminology) Requirement
**  ---------------------------------------------------------------------------------------------------------------------------------
**  Two office visits within the  | No                  | Look for a minimum of two distinct         | Office Visit
**  past 12 months                |                     | encounters within 12 months of the date    |
**                                |                     | of the current visit for which each of the |
**                                |                     | following is true:                         |
**                                |                     |   - the encounter diagnosis (primary or    |
**                                |                     |     secondary or co-morbidity diagnosis)   |
**                                |                     |     is listed in the CDC Malignant Cancer  |
**                                |                     |     Conditions value set                   |
**  ---------------------------------------------------------------------------------------------------------------------------------
**  Office visits with an         | No                  | The encounter is performed by an           | Oncology specialty
**  oncology specialist           |                     | oncologist as defined in the oncology      | designations (NUCC)
**  present                       |                     | specialty designations using the           |
**                                |                     | National Uniform Claim Committee           |
**                                |                     | (NUCC) classifications                     |
**  ---------------------------------------------------------------------------------------------------------------------------------
**  Office visits including CDC   | No                  | The encounter diagnosis (primary or        | CDC malignant cancer
**  malignant cancer              |                     | secondary or co-morbidity diagnosis)       | conditions
**  condition                     |                     | is listed in the CDC Malignant Cancer      |
**                                |                     | Conditions value set                       |
**  ----------------------------------------------------------------------------------------------------------------------------------
**
*/

define &quot;Encounter Period&quot;:
  Interval[Today() - 12 months, Today())"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="10"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString value="USCore Encounter Cancer Diagnoses"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;USCore Encounter Cancer Diagnoses&quot;:
  [Condition: category in &quot;Encounter Diagnosis Condition Category&quot;] CancerDiagnoses
    where CancerDiagnoses.code in &quot;CDC malignant cancer conditions&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="11"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Encounters with Cancer Diagnosis During Encounter Period"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="// encounter-diagnosis, problem-list and health-concern Conditions
// define &quot;US Core-Categorized Cancer Diagnoses&quot;:
//   Common.&quot;US Core-Categorized Conditions&quot; C
//     where C.code in Common.&quot;CDC malignant cancer conditions&quot;

// define &quot;Encounters with Cancer Diagnosis During Encounter Period&quot;:
//   [Encounter] Encounter
//     with &quot;US Core-Categorized Cancer Diagnoses&quot; CancerDiagnosis
//     such that date from Encounter.period.&quot;start&quot;.value in day of &quot;Encounter Period&quot;
//       and EndsWith(CancerDiagnosis.encounter.reference, Encounter.id)

define &quot;Encounters with Cancer Diagnosis During Encounter Period&quot;:
  [Encounter] Encounters
    where date from Encounters.period.&quot;start&quot; in day of &quot;Encounter Period&quot;
      and exists (
        Common.&quot;USCore Encounter Cancer Diagnoses&quot; CancerDiagnoses
          where EndsWith(CancerDiagnoses.encounter.reference, Encounters.id)
      )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="12"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Number of Encounters with Cancer Diagnosis During Encounter Period"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Number of Encounters with Cancer Diagnosis During Encounter Period&quot;:
  Count (&quot;Encounters with Cancer Diagnosis During Encounter Period&quot;)"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="13"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Has Two or More Encounters with Cancer Diagnosis During Encounter Period"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Has Two or More Encounters with Cancer Diagnosis During Encounter Period&quot;:
  &quot;Number of Encounters with Cancer Diagnosis During Encounter Period&quot; &gt;= 2"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="14"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString value="USCore Problem List Cancer Diagnoses"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;USCore Problem List Cancer Diagnoses&quot;:
  [Condition: category in &quot;Problem List Condition Category&quot;] CancerDiagnoses
    where CancerDiagnoses.code in &quot;CDC malignant cancer conditions&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="15"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Has Active Cancer Diagnosis on Problem List"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Has Active Cancer Diagnosis on Problem List&quot;:
  exists (
    Common.&quot;USCore Problem List Cancer Diagnoses&quot; CancerDiagnoses
      where CancerDiagnoses.category in Common.&quot;Problem List Condition Category&quot;
        and exists(
          CancerDiagnoses.clinicalStatus.coding ClinicalStatus
            where ClinicalStatus.code ~ 'active'
        )
  )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="16"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Is Active Cancer Treatment?"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Is Active Cancer Treatment?&quot;:
  if (Config.&quot;Active Cancer Treatment Encounters Condition Is Enabled&quot;) 
    then &quot;Has Two or More Encounters with Cancer Diagnosis During Encounter Period&quot;
      or &quot;Has Active Cancer Diagnosis on Problem List&quot;
  else false"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="17"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommonConfig"/>
    </extension>
    <extension url="name">
      <valueString value="End-Stage Disease Criteria Enabled"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="// CDC 2022 General Inclusion Criteria
define &quot;End-Stage Disease Criteria Enabled&quot;:
  true"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="18"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Conditions Likely Terminal for Opioid Prescribing"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Conditions Likely Terminal for Opioid Prescribing&quot;:
  if (Config.&quot;End-Stage Disease Criteria Enabled&quot;) then
    exists (
      Common.&quot;US Core-Categorized Conditions&quot; EOLC
        where EOLC.code in Common.&quot;Conditions likely terminal for opioid prescribing&quot;
          // and EOLC.clinicalStatus in Common.&quot;Active Condition&quot;
    )
  else false"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="19"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="CDC 2022 Guideline General Inclusion Criteria"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;CDC 2022 Guideline General Inclusion Criteria&quot;:
  not &quot;Patient Age Less Than 18&quot;
    and not &quot;Condition Positive for Sickle Cell&quot;
    and not &quot;Is Active Cancer Treatment?&quot;
    and not &quot;Conditions Likely Terminal for Opioid Prescribing&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="20"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommonConfig"/>
    </extension>
    <extension url="name">
      <valueString
                   value="PDMP Data Not Reviewed in Past 90 Days Criteria Enabled"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="// Recommendation 9
define &quot;PDMP Data Not Reviewed in Past 90 Days Criteria Enabled&quot;:
  true"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="21"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC09"/>
    </extension>
    <extension url="name">
      <valueString value="Look Back 90 Days"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Look Back 90 Days&quot;:
  Interval[Today() - 90 days, Today()]"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="22"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC09"/>
    </extension>
    <extension url="name">
      <valueString value="PDMP Data Not Reviewed in Past 90 Days"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;PDMP Data Not Reviewed in Past 90 Days&quot;:
  Config.&quot;PDMP Data Not Reviewed in Past 90 Days Criteria Enabled&quot;
    and not (
      exists (
        [Procedure: Common.&quot;PDMP review procedure&quot;] P
          where P.status ~ 'completed'
            and P.performed during &quot;Look Back 90 Days&quot;
      )
      or exists (
        [Observation: Common.&quot;PDMP data reviewed finding&quot;] O
          where O.status in { 'final', 'amended' }
            and (
              if O.effective is FHIR.Period
                then (O.effective as FHIR.Period) during day of &quot;Look Back 90 Days&quot;
                else if O.effective is FHIR.dateTime
                  then date from O.effective in day of &quot;Look Back 90 Days&quot;
                  else false
          )
      )
    )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="23"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC09"/>
    </extension>
    <extension url="name">
      <valueString value="Inclusion Criteria"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Inclusion Criteria&quot;:
  &quot;Patient Is Being Prescribed Opioid Analgesic with Ambulatory Misuse Potential&quot;
    and Routines.&quot;CDC 2022 Guideline General Inclusion Criteria&quot;
    and &quot;PDMP Data Not Reviewed in Past 90 Days&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="24"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC09"/>
    </extension>
    <extension url="name">
      <valueString value="Exclusion Criteria"/>
    </extension>
    <extension url="statement">
      <valueString value="define &quot;Exclusion Criteria&quot;:
  false"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="25"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSREC09"/>
    </extension>
    <extension url="name">
      <valueString value="Is Recommendation Applicable?"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define &quot;Is Recommendation Applicable?&quot;:
  &quot;Inclusion Criteria&quot;
    and not &quot;Exclusion Criteria&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="26"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Is Opioid Analgesic with Ambulatory Misuse Potential?"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function &quot;Is Opioid Analgesic with Ambulatory Misuse Potential?&quot;(value List&lt;MedicationRequest&gt;):
  (&quot;Get MedicationRequest Medication as Code&quot;(value)) Rx
    where Rx.medication in &quot;Opioid analgesics with ambulatory misuse potential&quot; 
      and Rx.category in &quot;Community&quot;"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="27"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString value="Get MedicationRequest Medication as Code"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function &quot;Get MedicationRequest Medication as Code&quot;(value List&lt;MedicationRequest&gt;):
  value Rx
    let Med: 
      if Rx.medication is Reference then singleton from (
        [Medication] M
          where M.id = (Last(Split((Rx.medication as FHIR.Reference).reference, '/')))
      ) else null
    return 
      MedicationRequest {
        id: Rx.id,
        status: Rx.status,
        intent: Rx.intent,
        category: Rx.category,
        medication: if Rx.medication is Reference then Med.code else Rx.medication as CodeableConcept,
        subject: Rx.subject,
        authoredOn: Rx.authoredOn,
        recorder: Rx.recorder,
        dosageInstruction: Rx.dosageInstruction,
        dispenseRequest: Rx.dispenseRequest
      }"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="28"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="FHIRHelpers"/>
    </extension>
    <extension url="name">
      <valueString value="ToString"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function ToString(value string): value.value"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="29"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="FHIRHelpers"/>
    </extension>
    <extension url="name">
      <valueString value="ToConcept"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function ToConcept(concept FHIR.CodeableConcept):
    if concept is null then
        null
    else
        System.Concept {
            codes: concept.coding C return ToCode(C),
            display: concept.text.value
        }"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="30"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="FHIRHelpers"/>
    </extension>
    <extension url="name">
      <valueString value="ToCode"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function ToCode(coding FHIR.Coding):
    if coding is null then
        null
    else
        System.Code {
          code: coding.code.value,
          system: coding.system.value,
          version: coding.version.value,
          display: coding.display.value
        }"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="31"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Is Subacute or Chronic Pain Prescription?"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="// End of Active Cancer Treatment Routine

/*
**  Routine #4
**  For Subacute or Chronic Pain Routine
**
**  Definition                  | Answer to Proceed   | Details                                        | Data (Terminology) Requirement
**  -----------------------------------------------------------------------------------------------------------------------------------
**  Order for opioid analgesic  | Yes                 | Order for opioid analgesics with ambulatory    | Opioid analgesics with
**  with expected supply        |                     | misuse potential with a supply duration of &gt;=  | ambulatory misuse potential
**  duration &gt;= 28 days         |                     | 28 days                                        |
**                              |                     |                                                |
**                              |                     | - Subacute definition = order for opioid       |
**                              |                     |   analgesics with ambulatory misuse            |
**                              |                     |   potential with a supply duration of one to   |
**                              |                     |   two months.                                  |
**                              |                     | - Chronic pain definition = order for opioid   |
**                              |                     |   analgesics with ambulatory misuse            |
**                              |                     |   potential with a supply duration of &gt;= two   |
**                              |                     |   months.                                      |
**  -----------------------------------------------------------------------------------------------------------------------------------
**
*/

define function &quot;Is Subacute or Chronic Pain Prescription?&quot;(prescription FHIR.MedicationRequest):
  &quot;Is Subacute or Chronic Pain Using Expected Supply Duration&quot;(prescription)
    or &quot;Is Subacute or Chronic Pain Using Validity Period&quot;(prescription)"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="32"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString
                   value="Is Subacute or Chronic Pain Using Expected Supply Duration"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function &quot;Is Subacute or Chronic Pain Using Expected Supply Duration&quot;(prescription FHIR.MedicationRequest):
  (
    prescription.dispenseRequest is not null
      and prescription.dispenseRequest.expectedSupplyDuration is not null
      and (
        Common.GetDurationInDays(prescription.dispenseRequest.expectedSupplyDuration) &gt;= 28 days 
      )
  )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="33"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSCommon"/>
    </extension>
    <extension url="name">
      <valueString value="GetDurationInDays"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function GetDurationInDays(value FHIR.Duration):
  if value is null then null
  else
    case
      when value.code.value ~ 'a' then System.Quantity{ value: value.value.value * 365.0, unit: 'days' }
      when value.code.value ~ 'mo' then System.Quantity{ value: value.value.value * 30.0, unit: 'days' }
      when value.code.value ~ 'wk' then System.Quantity{ value: value.value.value * 7.0, unit: 'days' }
      when value.code.value ~ 'd' then System.Quantity{ value: value.value.value, unit: 'days' }
      when value.code.value ~ 'h' then System.Quantity{ value: value.value.value / 24.0, unit: 'days' }
      when value.code.value ~ 'min' then System.Quantity{ value: value.value.value / 60.0 / 24.0, unit: 'days' }
      when value.code.value ~ 's' then System.Quantity{ value: value.value.value / 60.0 / 60.0 / 24.0, unit: 'days' }
      when value.code.value ~ 'ms' then System.Quantity{ value: value.value.value / 60.0 / 60.0 / 24.0 / 1000.0, unit: 'days' }
      when value.code.value is null then Message(1000, true, 'Undefined', 'Error', 'Duration unit code is null')
      else Message(1000, true, 'Undefined', 'Error', 'Unsupported duration unit code: ' + value.code.value)
end"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="34"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="OpioidCDSRoutines"/>
    </extension>
    <extension url="name">
      <valueString value="Is Subacute or Chronic Pain Using Validity Period"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function &quot;Is Subacute or Chronic Pain Using Validity Period&quot;(prescription FHIR.MedicationRequest):
  (
    prescription.dispenseRequest is not null
      and prescription.dispenseRequest.validityPeriod is not null
      and (
        days between prescription.dispenseRequest.validityPeriod.start and prescription.dispenseRequest.validityPeriod.end &gt;= 28 
      )
  )"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="35"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="FHIRHelpers"/>
    </extension>
    <extension url="name">
      <valueString value="ToDateTime"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function ToDateTime(value dateTime): value.value"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="36"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="FHIRHelpers"/>
    </extension>
    <extension url="name">
      <valueString value="ToString"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function ToString(value ProcedureStatus): value.value"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="37"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="FHIRHelpers"/>
    </extension>
    <extension url="name">
      <valueString value="ToInterval"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function ToInterval(period FHIR.Period):
    if period is null then
        null
    else
        if period.&quot;start&quot; is null then
            Interval(period.&quot;start&quot;.value, period.&quot;end&quot;.value]
        else
            Interval[period.&quot;start&quot;.value, period.&quot;end&quot;.value]"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="38"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="FHIRHelpers"/>
    </extension>
    <extension url="name">
      <valueString value="ToString"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function ToString(value ObservationStatus): value.value"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="39"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
    <extension url="libraryName">
      <valueString value="FHIRHelpers"/>
    </extension>
    <extension url="name">
      <valueString value="ToDateTime"/>
    </extension>
    <extension url="statement">
      <valueString
                   value="define function ToDateTime(value instant): value.value"/>
    </extension>
    <extension url="displaySequence">
      <valueInteger value="40"/>
    </extension>
  </extension>
  <extension
             url="http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-effectiveDataRequirements" id="effective-data-requirements">
    <valueCanonical value="#effective-data-requirements"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-softwaresystem">
    <valueReference>🔗 
      <reference value="Device/cqf-tooling"/>
    </valueReference>
  </extension>
  <url
       value="http://fhir.org/guides/cdc/opioid-cds/PlanDefinition/opioidcds-09"/>
  <identifier>
    <use value="official"/>
    <value value="cdc-opioid-guidance"/>
  </identifier>
  <version value="2022.1.0"/>
  <name value="PlanDefinition_Recommendation_09_Order_Sign"/>
  <title
         value="Recommendation #9 - Consider Patient's History of Controlled Substance Prescriptions"/>
  <type>
    <coding>
      <system
              value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
      <code value="eca-rule"/>
      <display value="ECA Rule"/>
    </coding>
  </type>
  <status value="draft"/>
  <experimental value="true"/>
  <date value="2025-08-06"/>
  <publisher value="Centers for Disease Control and Prevention (CDC)"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="https://www.cdc.gov"/>
    </telecom>
  </contact>
  <description
               value="When prescribing initial opioid therapy for acute, subacute, or chronic pain, and periodically during opioid therapy for chronic pain, clinicians should review the patient's history of controlled substance prescriptions using state prescription drug monitoring program (PDMP) data to determine whether the patient is receiving opioid dosages or combinations that put the patient at high risk for overdose."/>
  <useContext>
    <code>
      <system
              value="http://terminology.hl7.org/CodeSystem/usage-context-type"/>
      <code value="focus"/>
      <display value="Clinical Focus"/>
    </code>
    <valueCodeableConcept>
      <coding>
        <system value="http://snomed.info/sct"/>
        <code value="182888003"/>
        <display value="Medication requested (situation)"/>
      </coding>
    </valueCodeableConcept>
  </useContext>
  <useContext>
    <code>
      <system
              value="http://terminology.hl7.org/CodeSystem/usage-context-type"/>
      <code value="focus"/>
      <display value="Clinical Focus"/>
    </code>
    <valueCodeableConcept>
      <coding>
        <system value="http://snomed.info/sct"/>
        <code value="82423001"/>
        <display value="Chronic pain (finding)"/>
      </coding>
    </valueCodeableConcept>
  </useContext>
  <useContext>
    <code>
      <system
              value="http://terminology.hl7.org/CodeSystem/usage-context-type"/>
      <code value="focus"/>
      <display value="Clinical Focus"/>
    </code>
    <valueCodeableConcept>
      <coding>
        <system value="http://snomed.info/sct"/>
        <code value="274663001"/>
        <display value="Acute pain (finding)"/>
      </coding>
    </valueCodeableConcept>
  </useContext>
  <useContext>
    <code>
      <system
              value="http://terminology.hl7.org/CodeSystem/usage-context-type"/>
      <code value="focus"/>
      <display value="Clinical Focus"/>
    </code>
    <valueCodeableConcept>
      <text value="Subacute pain"/>
    </valueCodeableConcept>
  </useContext>
  <purpose
           value="The 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain is intended to improve communication between clinicians and patients about the benefits and risks of pain treatments, including opioid therapy; improve the effectiveness and safety of pain treatment; mitigate pain; improve function and quality of life for patients with pain; and reduce risks associated with opioid pain therapy, including opioid use disorder, overdose, and death. The recommendations do not apply to pain related to sickle cell disease or cancer or to patients receiving palliative or end-of-life care."/>
  <usage
         value="At a minimum, during long-term opioid therapy, PDMP data should be reviewed before an initial opioid prescription and then every 3 months or more frequently."/>
  <copyright value="© CDC 2016+."/>
  <topic>
    <text value="Opioid Prescribing"/>
  </topic>
  <author>
    <name value="Kensaku Kawamoto, MD, PhD, MHS"/>
  </author>
  <author>
    <name value="Bryn Rhodes"/>
  </author>
  <author>
    <name value="Floyd Eisenberg, MD, MPH"/>
  </author>
  <author>
    <name value="Robert McClure, MD, MPH"/>
  </author>
  <relatedArtifact>
    <type value="documentation"/>
    <display
             value="2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain"/>
    <url value="https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm"/>
    <document>
      <url value="https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm"/>
    </document>
  </relatedArtifact>
  <library
           value="http://fhir.org/guides/cdc/opioid-cds/Library/OpioidCDSREC09"/>
  <action>
    <extension
               url="http://hl7.org/fhir/StructureDefinition/cqf-strengthOfRecommendation">
      <valueCodeableConcept>
        <coding>
          <system
                  value="http://terminology.hl7.org/CodeSystem/recommendation-strength"/>
          <code value="weak"/>
          <display value="Weak"/>
        </coding>
      </valueCodeableConcept>
    </extension>
    <extension
               url="http://hl7.org/fhir/StructureDefinition/cqf-qualityOfEvidence">
      <valueCodeableConcept>
        <coding>
          <system
                  value="http://terminology.hl7.org/CodeSystem/evidence-quality"/>
          <code value="very-low"/>
          <display value="Very low quality"/>
        </coding>
      </valueCodeableConcept>
    </extension>
    <title value="Before Ordering Opioids, Review PDMP Data"/>
    <description
                 value="Review PDMP data for this patient before completing an opioid order.

For guidance about utilizing PDMP information to improve patient safety, see [Recommendation 9 of the 2022 CDC Clinical Practice Guideline](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=Clinicians%20should%20take,see%20Recommendation%2010).).

[CDC advises not to dismiss patients from your practice on the basis of PDMP information](https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm#:~:text=Clinicians%20should%20not%20dismiss,Recommendations%208%20and%2012%5D).)"/>
    <priority value="urgent"/>
    <trigger>
      <type value="named-event"/>
      <name value="order-sign"/>
    </trigger>
    <condition>
      <kind value="applicability"/>
      <expression>
        <description
                     value="Check whether the current order is for an opioid with ambulatory misuse potential, if the 2022 CDC guideline general inclusion criteria is met or there exists evidence of a prescription drug monitoring program (PDMP) review procedure or finding occurred in the past 90 days."/>
        <language value="text/cql.identifier"/>
        <expression value="Is Recommendation Applicable?"/>
      </expression>
    </condition>
    <groupingBehavior value="visual-group"/>
    <selectionBehavior value="any"/>
    <action>
      <description value="Access Data - Launch app to review PDMP data"/>
    </action>
    <action>
      <description value="Document - PDMP data reviewed, snooze 3 months"/>
    </action>
    <action>
      <description value="Snooze* - N/A see comment, snooze 3 months"/>
    </action>
  </action>
</PlanDefinition>